Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_O05
(846 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y5A9|YTHD2_HUMAN YTH domain protein 2 (High-glucose-re... 257 2e-68
sp|P59326|YTHD1_MOUSE YTH domain protein 1 (Dermatomyositis... 252 1e-66
sp|Q9BYJ9|YTHD1_HUMAN YTH domain protein 1 (Dermatomyositis... 247 3e-65
sp|Q9QY02|YT521_RAT Putative splicing factor YT521 (RA301-b... 64 7e-10
sp|Q96MU7|YT521_HUMAN Putative splicing factor YT521 63 9e-10
sp|P46265|TBB5_ORYSA Tubulin beta-5 chain (Beta-5 tubulin) 32 2.2
sp|P75072|Y042_MYCPN Hypothetical protein MPN042 (B01_orf672) 32 2.2
sp|Q9ZPP0|TBB1_ELEIN Tubulin beta-1 chain (Beta-1 tubulin) 32 2.2
sp|O52271|RPOB_RICPR DNA-directed RNA polymerase beta chain... 32 2.9
sp|Q9RH43|RPOB_RICMA DNA-directed RNA polymerase beta chain... 32 2.9
>sp|Q9Y5A9|YTHD2_HUMAN YTH domain protein 2 (High-glucose-regulated protein 8) (NY-REN-2
antigen) (CLL-associated antigen KW-14)
Length = 579
Score = 257 bits (657), Expect = 2e-68
Identities = 119/168 (70%), Positives = 140/168 (83%)
Frame = +2
Query: 92 DLDTNLKNAKFFVIKSYSEDDVYRSIKYQIWCSTETGNRRLDNAYSNSGGEIPIYLFFSV 271
D D NLK+ + F+IKSYSEDD++RSIKY IWCSTE GN+RLD AY + G+ P+YL FSV
Sbjct: 402 DFDWNLKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSV 461
Query: 272 NGSGHFCGVAEMVSPVDYKTRATVWAQGKWKGQFRVRWIFVKDVPNSQLRHIRIETNENK 451
NGSGHFCGVAEM S VDY T A VW+Q KWKG+F VRWIFVKDVPNSQLRHIR+E NENK
Sbjct: 462 NGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENK 521
Query: 452 PVTNSRDVTEIPLEKGRQVLKIIANFKATSSIYDDFDHYEQRELSESN 595
PVTNSRD E+PLEK +QVLKIIA++K T+SI+DDF HYE+R+ E +
Sbjct: 522 PVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEES 569
>sp|P59326|YTHD1_MOUSE YTH domain protein 1 (Dermatomyositis associated with cancer
putative autoantigen 1 homolog) (DACA-1 homolog)
Length = 559
Score = 252 bits (643), Expect = 1e-66
Identities = 114/166 (68%), Positives = 139/166 (83%)
Frame = +2
Query: 92 DLDTNLKNAKFFVIKSYSEDDVYRSIKYQIWCSTETGNRRLDNAYSNSGGEIPIYLFFSV 271
+ D NLK+ + F+IKSYSEDD++RSIKY IWCSTE GN+RLD A+ + + P+YL FSV
Sbjct: 381 EFDWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKGPVYLLFSV 440
Query: 272 NGSGHFCGVAEMVSPVDYKTRATVWAQGKWKGQFRVRWIFVKDVPNSQLRHIRIETNENK 451
NGSGHFCGVAEM SPVDY T A VW+Q KWKG+F V+WIFVKDVPN+QLRHIR+E N+NK
Sbjct: 441 NGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWIFVKDVPNNQLRHIRLENNDNK 500
Query: 452 PVTNSRDVTEIPLEKGRQVLKIIANFKATSSIYDDFDHYEQRELSE 589
PVTNSRD E+PLEK +QVLKIIA++K T+SI+DDF HYE+R+ E
Sbjct: 501 PVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEE 546
>sp|Q9BYJ9|YTHD1_HUMAN YTH domain protein 1 (Dermatomyositis associated with cancer
putative autoantigen 1) (DACA-1)
Length = 559
Score = 247 bits (630), Expect = 3e-65
Identities = 112/166 (67%), Positives = 139/166 (83%)
Frame = +2
Query: 92 DLDTNLKNAKFFVIKSYSEDDVYRSIKYQIWCSTETGNRRLDNAYSNSGGEIPIYLFFSV 271
+ + NLK+ + F+IKSYSEDD++RSIKY IWCSTE GN+RLD+A+ + P+YL FSV
Sbjct: 381 EFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSV 440
Query: 272 NGSGHFCGVAEMVSPVDYKTRATVWAQGKWKGQFRVRWIFVKDVPNSQLRHIRIETNENK 451
NGSGHFCGVAEM SPVDY T A VW+Q KWKG+F V+WIFVKDVPN+QLRHIR+E N+NK
Sbjct: 441 NGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNK 500
Query: 452 PVTNSRDVTEIPLEKGRQVLKIIANFKATSSIYDDFDHYEQRELSE 589
PVTNSRD E+PLEK +QVLKII+++K T+SI+DDF HYE+R+ E
Sbjct: 501 PVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEE 546
>sp|Q9QY02|YT521_RAT Putative splicing factor YT521 (RA301-binding protein)
Length = 738
Score = 63.5 bits (153), Expect = 7e-10
Identities = 45/145 (31%), Positives = 77/145 (53%), Gaps = 7/145 (4%)
Frame = +2
Query: 95 LDTNLKNAKFFVIKSYSEDDVYRSIKYQIWCSTETGNRRLDNAYSNSGGEIPIYLFFSVN 274
L + L++A+FF+IKS + ++V + +W + ++L+ A+ ++ I L FSV
Sbjct: 351 LKSVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVI---LIFSVR 407
Query: 275 GSGHFCGVAEMVS-------PVDYKTRATVWAQGKWKGQFRVRWIFVKDVPNSQLRHIRI 433
SG F G A + S P+ + A + A+ G F++ WI +++P ++ H+
Sbjct: 408 ESGKFQGFARLSSESHHGGSPIHWVLPAGMSAK-MLGGVFKIDWICRRELPFTKSAHLTN 466
Query: 434 ETNENKPVTNSRDVTEIPLEKGRQV 508
NE+KPV RD EI LE G Q+
Sbjct: 467 PWNEHKPVKIGRDGQEIELECGTQL 491
>sp|Q96MU7|YT521_HUMAN Putative splicing factor YT521
Length = 727
Score = 63.2 bits (152), Expect = 9e-10
Identities = 44/141 (31%), Positives = 75/141 (53%), Gaps = 7/141 (4%)
Frame = +2
Query: 107 LKNAKFFVIKSYSEDDVYRSIKYQIWCSTETGNRRLDNAYSNSGGEIPIYLFFSVNGSGH 286
L++A+FF+IKS + ++V + +W + ++L+ A+ ++ I L FSV SG
Sbjct: 352 LQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARSVI---LIFSVRESGK 408
Query: 287 FCGVAEMVS-------PVDYKTRATVWAQGKWKGQFRVRWIFVKDVPNSQLRHIRIETNE 445
F G A + S P+ + A + A+ G F++ WI +++P ++ H+ NE
Sbjct: 409 FQGFARLSSESHHGGSPIHWVLPAGMSAK-MLGGVFKIDWICRRELPFTKSAHLTNPWNE 467
Query: 446 NKPVTNSRDVTEIPLEKGRQV 508
+KPV RD EI LE G Q+
Sbjct: 468 HKPVKIGRDGQEIELECGTQL 488
>sp|P46265|TBB5_ORYSA Tubulin beta-5 chain (Beta-5 tubulin)
Length = 447
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 3/51 (5%)
Frame = +2
Query: 35 ENNNSSQIV--INNKINASLCDLDTN-LKNAKFFVIKSYSEDDVYRSIKYQ 178
+N NSS V I N + +S+CD+ N LK A F+ S S +++R + Q
Sbjct: 334 QNKNSSYFVEWIPNNVKSSVCDIPPNGLKMASTFIGNSTSIQEMFRRVSEQ 384
>sp|P75072|Y042_MYCPN Hypothetical protein MPN042 (B01_orf672)
Length = 672
Score = 32.0 bits (71), Expect = 2.2
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 7/102 (6%)
Frame = +2
Query: 353 GKWKGQFRVRWIFVKDVPNSQLRHIRIET-------NENKPVTNSRDVTEIPLEKGRQVL 511
G W+G+F+V + F VP+ + HI++ T E K + + +I E L
Sbjct: 575 GYWRGKFKVTYSFDGVVPSWKYGHIQVRTPQYSFNKQEQKILFVPHAIQKIAAEGSN--L 632
Query: 512 KIIANFKATSSIYDDFDHYEQRELSESNQ*VFKIMYKI*TKN 637
+I F + D+F+HY +L++ V ++Y I T++
Sbjct: 633 DLINPFLKDQKL-DEFEHYHP-DLTKPLDLVAYLLYAITTRS 672
>sp|Q9ZPP0|TBB1_ELEIN Tubulin beta-1 chain (Beta-1 tubulin)
Length = 445
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 3/51 (5%)
Frame = +2
Query: 35 ENNNSSQIV--INNKINASLCDLDTN-LKNAKFFVIKSYSEDDVYRSIKYQ 178
+N NSS V I N + +S+CD+ N LK A F+ S S +++R + Q
Sbjct: 334 QNKNSSYFVEWIPNNVKSSVCDIPPNGLKMASTFIGNSTSIQEMFRRVSEQ 384
>sp|O52271|RPOB_RICPR DNA-directed RNA polymerase beta chain (RNAP beta subunit)
(Transcriptase beta chain) (RNA polymerase beta subunit)
Length = 1374
Score = 31.6 bits (70), Expect = 2.9
Identities = 14/52 (26%), Positives = 26/52 (50%)
Frame = +2
Query: 428 RIETNENKPVTNSRDVTEIPLEKGRQVLKIIANFKATSSIYDDFDHYEQREL 583
RI+ N + S +VT + ++ + +++I+ K I DD DH R +
Sbjct: 419 RIKMNSRLELNISEEVTVLTIDDIKNIVRILVELKDGKGIIDDIDHLGNRRV 470
>sp|Q9RH43|RPOB_RICMA DNA-directed RNA polymerase beta chain (RNAP beta subunit)
(Transcriptase beta chain) (RNA polymerase beta subunit)
Length = 1373
Score = 31.6 bits (70), Expect = 2.9
Identities = 16/63 (25%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = +2
Query: 398 DVPNSQLRHI-RIETNENKPVTNSRDVTEIPLEKGRQVLKIIANFKATSSIYDDFDHYEQ 574
DV L + RI+ N + S +VT + ++ + +++++ K I DD DH
Sbjct: 408 DVDRYDLSEVGRIKMNSRLELNISEEVTVLTIDDIKNIVRVLVELKDGKGIIDDIDHLGN 467
Query: 575 REL 583
R +
Sbjct: 468 RRV 470
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,998,359
Number of Sequences: 369166
Number of extensions: 1814448
Number of successful extensions: 5020
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4458
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4841
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)