Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_N08
(752 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P40227|TCPZ_HUMAN T-complex protein 1, zeta subunit (TCP... 289 5e-78
sp|O77622|TCPZ_RABIT T-complex protein 1, zeta subunit (TCP... 288 8e-78
sp|P80317|TCPZ_MOUSE T-complex protein 1, zeta subunit (TCP... 288 1e-77
sp|Q5RCD2|TCPZ_PONPY T-complex protein 1, zeta subunit (TCP... 283 3e-76
sp|Q92526|TCPW_HUMAN T-complex protein 1, zeta-2 subunit (T... 275 1e-73
sp|Q61390|TCPW_MOUSE T-complex protein 1, zeta-2 subunit (T... 263 4e-70
sp|P46550|TCPZ_CAEEL T-complex protein 1, zeta subunit (TCP... 254 1e-67
sp|O94515|TCPZ_SCHPO T-complex protein 1, zeta subunit (TCP... 233 5e-61
sp|P39079|TCPZ_YEAST T-complex protein 1, zeta subunit (TCP... 199 7e-51
sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome s... 147 4e-35
>sp|P40227|TCPZ_HUMAN T-complex protein 1, zeta subunit (TCP-1-zeta) (CCT-zeta)
(CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence
related protein 2)
Length = 531
Score = 289 bits (740), Expect = 5e-78
Identities = 149/245 (60%), Positives = 189/245 (77%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
I++RV+K+I LKRKVC V+INQKGIDPFSLD L+KEGI+ LRRAKRR
Sbjct: 267 IEDRVKKIIELKRKVCGDSDKGF-------VVINQKGIDPFSLDALSKEGIVALRRAKRR 319
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERL+LACGG A+NS D+LSPDCLG AGLVYEYTLG+EKFTF+E+C NP+SVTLLIKGP
Sbjct: 320 NMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGP 379
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSETLTGRVTYGVEA 555
NKHTLTQIKDAV DGL+AVKNAIDD CV+PGAGA E+A L+K+ ++ GR GV+A
Sbjct: 380 NKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQA 439
Query: 556 FARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPMKP 735
FA LL+IP++LAQNSGFD+++ VK+ E + +G++ +G++L++GEPM
Sbjct: 440 FADALLIIPKVLAQNSGFDLQETLVKIQAE---------HSESGQL-VGVDLNTGEPMVA 489
Query: 736 HDAGI 750
+ G+
Sbjct: 490 AEVGV 494
>sp|O77622|TCPZ_RABIT T-complex protein 1, zeta subunit (TCP-1-zeta) (CCT-zeta)
Length = 531
Score = 288 bits (738), Expect = 8e-78
Identities = 146/245 (59%), Positives = 189/245 (77%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
I++RV+K++ LK+KVC V+INQKGIDPFSLD LAKEGI+ LRRAKRR
Sbjct: 267 IEDRVKKIVELKKKVCGDSDKGF-------VVINQKGIDPFSLDALAKEGIVALRRAKRR 319
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERL+LACGG +NS+D+L+PDCLG AGLVYEYTLG+EKFTF+E+C NP+SVTLL+KGP
Sbjct: 320 NMERLTLACGGVPLNSLDDLNPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLVKGP 379
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSETLTGRVTYGVEA 555
NKHTLTQIKDA+ DGL+AVKNAIDD CV+PGAGA E+A L+KY ++ GR GV+A
Sbjct: 380 NKHTLTQIKDAIRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKYKSSVKGRAQLGVQA 439
Query: 556 FARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPMKP 735
FA LL+IP++LAQNSGFD+++ VK+ E + +G++ +G++L++GEPM
Sbjct: 440 FADALLIIPKVLAQNSGFDLQETLVKIRTE---------HSESGQL-VGVDLNTGEPMVA 489
Query: 736 HDAGI 750
+ GI
Sbjct: 490 AEVGI 494
>sp|P80317|TCPZ_MOUSE T-complex protein 1, zeta subunit (TCP-1-zeta) (CCT-zeta)
(CCT-zeta-1)
Length = 531
Score = 288 bits (737), Expect = 1e-77
Identities = 147/245 (60%), Positives = 188/245 (76%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
I++RV+K+I LK+KVC V+INQKGIDPFSLD LAKEGI+ LRRAKRR
Sbjct: 267 IEDRVKKIIELKKKVCGDSDKGF-------VVINQKGIDPFSLDALAKEGIVALRRAKRR 319
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERL+LACGG A+NS D+L+PDCLG AGLVYEYTLG+EKFTF+E+C NP+SVTLL+KGP
Sbjct: 320 NMERLTLACGGIALNSFDDLNPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLVKGP 379
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSETLTGRVTYGVEA 555
NKHTLTQIKDA+ DGL+AVKNAIDD CV+PGAGA E+A L+KY ++ GR GV+A
Sbjct: 380 NKHTLTQIKDAIRDGLRAVKNAIDDGCVVPGAGAVEVALAEALIKYKPSVKGRAQLGVQA 439
Query: 556 FARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPMKP 735
FA LL+IP++LAQNSGFD+++ VK+ E + +G++ +G++L +GEPM
Sbjct: 440 FADALLIIPKVLAQNSGFDLQETLVKVQAE---------HSESGQL-VGVDLSTGEPMVA 489
Query: 736 HDAGI 750
+ G+
Sbjct: 490 AEMGV 494
>sp|Q5RCD2|TCPZ_PONPY T-complex protein 1, zeta subunit (TCP-1-zeta) (CCT-zeta)
Length = 531
Score = 283 bits (725), Expect = 3e-76
Identities = 147/245 (60%), Positives = 188/245 (76%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
I++RV+K+I LKRKVC V+INQKGIDPFSLD L+KEGI+ LRRAKRR
Sbjct: 267 IEDRVKKIIELKRKVCGDSDKGF-------VVINQKGIDPFSLDALSKEGIVALRRAKRR 319
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERL+LACGG A+NS D+LSPD LG AGLVYEYTLG+EKFTF+E+C NP+SVTLLIKGP
Sbjct: 320 NMERLTLACGGVALNSFDDLSPDQLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGP 379
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSETLTGRVTYGVEA 555
NKHTLTQIKDAV DGL+AV+NAIDD CV+PGAGA E+A L+K+ ++ GR GV+A
Sbjct: 380 NKHTLTQIKDAVRDGLRAVRNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQA 439
Query: 556 FARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPMKP 735
FA LL+IP++LAQNSGFD+++ VK+ E + +G++ +G++L++GEPM
Sbjct: 440 FADALLIIPKVLAQNSGFDLQETLVKIQAE---------HSESGQL-VGVDLNTGEPMVA 489
Query: 736 HDAGI 750
+ G+
Sbjct: 490 AEVGV 494
>sp|Q92526|TCPW_HUMAN T-complex protein 1, zeta-2 subunit (TCP-1-zeta-2) (CCT-zeta-2)
(TCP-1-zeta-like) (CCT-zeta-like) (Testis-specific
Tcp20) (Testis-specific protein TSA303)
Length = 530
Score = 275 bits (703), Expect = 1e-73
Identities = 140/245 (57%), Positives = 181/245 (73%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
I++RV+K+I LK KVC V+INQKGIDPFSLD LAK GI+ LRRAKRR
Sbjct: 267 IEDRVQKIIDLKDKVCAQSNKGF-------VVINQKGIDPFSLDSLAKHGIVALRRAKRR 319
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERLSLACGG A+NS ++L+ DCLG AGLVYEYTLG+EKFTF+EEC NP SVTLL+KGP
Sbjct: 320 NMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGP 379
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSETLTGRVTYGVEA 555
NKHTLTQ+KDA+ DGL+A+KNAI+D C++PGAGA E+A L+ Y ++ GR GV+A
Sbjct: 380 NKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQA 439
Query: 556 FARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPMKP 735
FA LL+IP++LAQN+G+D ++ VK+ E + + +G++L++GEPM
Sbjct: 440 FADALLIIPKVLAQNAGYDPQETLVKVQAE----------HVESKQLVGVDLNTGEPMVA 489
Query: 736 HDAGI 750
DAG+
Sbjct: 490 ADAGV 494
>sp|Q61390|TCPW_MOUSE T-complex protein 1, zeta-2 subunit (TCP-1-zeta-2) (CCT-zeta-2)
(Cctz-2)
Length = 531
Score = 263 bits (672), Expect = 4e-70
Identities = 135/245 (55%), Positives = 179/245 (73%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
I++RV+K+I LK+KVC V+INQKGIDP SL++LAK I+ LRRAKRR
Sbjct: 267 IEDRVQKIIDLKQKVCAESNKGF-------VVINQKGIDPVSLEMLAKHNIVALRRAKRR 319
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
N+ERL+LACGG A+NS + LS +CLG AGLV+EY LG+EKFTF+E+C NP SVTLL+KGP
Sbjct: 320 NLERLTLACGGLAVNSFEGLSEECLGHAGLVFEYALGEEKFTFIEDCVNPLSVTLLVKGP 379
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSETLTGRVTYGVEA 555
NKHTL QIKDA+ DGL+AVKNAI+D CV+PGAGA E+A L+ Y + GRV G++A
Sbjct: 380 NKHTLIQIKDALRDGLRAVKNAIEDGCVVPGAGAVEVAIAEALVNYKHRVQGRVRLGIQA 439
Query: 556 FARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPMKP 735
FA LL+IP++LAQNSG+D+++ +K+ + + E LG++L++GEPM
Sbjct: 440 FADALLIIPKVLAQNSGYDLQETLIKIQTKHAESKE----------LLGIDLNTGEPMAA 489
Query: 736 HDAGI 750
+AGI
Sbjct: 490 AEAGI 494
>sp|P46550|TCPZ_CAEEL T-complex protein 1, zeta subunit (TCP-1-zeta) (CCT-zeta)
Length = 539
Score = 254 bits (650), Expect = 1e-67
Identities = 138/240 (57%), Positives = 173/240 (72%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
I RV K+I LK+KV V+INQKGIDP SLDLLA EGIL LRRAKRR
Sbjct: 267 ITRRVHKIIELKKKVIDNSPDGKNKGF---VVINQKGIDPPSLDLLASEGILALRRAKRR 323
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERL LA GG A+NSVD+L+P+ LG AGLVYE++LG+EK+TF+EEC+ P+SVTLLIKGP
Sbjct: 324 NMERLQLAVGGEAVNSVDDLTPEDLGWAGLVYEHSLGEEKYTFIEECRAPKSVTLLIKGP 383
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSETLTGRVTYGVEA 555
NKHT+TQIKDA++DGL+AV N I DK V+PGA AFE+AA++ L K E L GR G EA
Sbjct: 384 NKHTITQIKDAIHDGLRAVFNTIVDKAVLPGAAAFEIAAYVMLKKDVENLKGRAKLGAEA 443
Query: 556 FARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPMKP 735
FA+ LLVIP+ LA N G+D ++ VKL+ E +IA+GL+L++G ++P
Sbjct: 444 FAQALLVIPKTLAVNGGYDAQETLVKLIEE--------KTAAGPDIAVGLDLETGGAVEP 495
>sp|O94515|TCPZ_SCHPO T-complex protein 1, zeta subunit (TCP-1-zeta) (CCT-zeta)
Length = 535
Score = 233 bits (593), Expect = 5e-61
Identities = 127/247 (51%), Positives = 167/247 (67%), Gaps = 2/247 (0%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
+D ++RK++ LK++VC V+INQKGIDP SLD+LAK GI+ LRRAKRR
Sbjct: 265 VDNKLRKIVELKKEVCERDPTANF------VIINQKGIDPLSLDVLAKNGIMALRRAKRR 318
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERL LACGG A NSVD+L+P+ LG AG VYE TLG+EK+TFVE+ K+P+S T+LI GP
Sbjct: 319 NMERLQLACGGVAQNSVDDLNPEVLGWAGSVYERTLGEEKYTFVEDVKDPKSATILIHGP 378
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFEL--AAHLDLMKYSETLTGRVTYGV 549
N +T+ QI+DA DGL+AVKNA++D C+I GAGAFE+ AAHL ++ + G+ GV
Sbjct: 379 NTYTIQQIQDATRDGLRAVKNAVEDNCLIVGAGAFEVACAAHLRNKFAAKEVKGKAKMGV 438
Query: 550 EAFARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEPM 729
A+A LL+IP+ LA NS +D +D V L E + G K+ GL+L +G P
Sbjct: 439 YAYADALLIIPKTLAANSSYDTQDAIVALQEE-----ASEGYKV------GLDLKTGMPF 487
Query: 730 KPHDAGI 750
P GI
Sbjct: 488 DPEVEGI 494
>sp|P39079|TCPZ_YEAST T-complex protein 1, zeta subunit (TCP-1-zeta) (CCT-zeta)
Length = 546
Score = 199 bits (506), Expect = 7e-51
Identities = 114/248 (45%), Positives = 153/248 (61%), Gaps = 3/248 (1%)
Frame = +1
Query: 16 IDERVRKVIALKRKVCXXXXXXXXXXXXXXVMINQKGIDPFSLDLLAKEGILGLRRAKRR 195
+D +++K+I LK +VC V+INQKGIDP SLD+ AK IL LRRAKRR
Sbjct: 270 VDAKLKKIIDLKNEVCGMDPDKGF------VIINQKGIDPMSLDVFAKHNILALRRAKRR 323
Query: 196 NMERLSLACGGYAINSVDELSPDCLGMAGLVYEYTLGDEKFTFVEECKNPQSVTLLIKGP 375
NMERL L GG A NSV++LSP LG +GLVY+ T+G+EKFT+V E +P+S T+LIKG
Sbjct: 324 NMERLQLVTGGEAQNSVEDLSPQILGFSGLVYQETIGEEKFTYVTENTDPKSCTILIKGS 383
Query: 376 NKHTLTQIKDAVNDGLKAVKNAIDDKCVIPGAGAFELAAHLDLMKYSET---LTGRVTYG 546
+ L Q KDAV DGL+AV N + DK +IPGAGAF +A L + G+ G
Sbjct: 384 THYALAQTKDAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTG 443
Query: 547 VEAFARGLLVIPRILAQNSGFDVKDCEVKLLHEIRKLLEANGNKITGEIALGLNLDSGEP 726
+EAFA LLVIP+ L +NSGFD D + E+ +++ + +G++L+ G+
Sbjct: 444 IEAFAEALLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRY-----VGVDLNIGDS 498
Query: 727 MKPHDAGI 750
P GI
Sbjct: 499 CDPTIEGI 506
>sp|O28045|THSA_ARCFU Thermosome alpha subunit (Thermosome subunit 1) (Chaperonin alpha
subunit)
Length = 545
Score = 147 bits (370), Expect = 4e-35
Identities = 84/215 (39%), Positives = 128/215 (59%)
Frame = +1
Query: 106 VMINQKGIDPFSLDLLAKEGILGLRRAKRRNMERLSLACGGYAINSVDELSPDCLGMAGL 285
V+ QKGID + LAK GIL +RR K+ ++E+++ ACG I + E++ LG A L
Sbjct: 290 VVFCQKGIDDLAQYYLAKAGILAVRRVKQSDIEKIAKACGAKIITDLREITSADLGEAEL 349
Query: 286 VYEYTLGDEKFTFVEECKNPQSVTLLIKGPNKHTLTQIKDAVNDGLKAVKNAIDDKCVIP 465
V E +GDEK F+E CKNP++VT+LI+G ++H + +++ ++ D +K VK A++ V+
Sbjct: 350 VEERKVGDEKMVFIEGCKNPKAVTILIRGGSEHVVDEVERSLQDAIKVVKTALESGKVVA 409
Query: 466 GAGAFELAAHLDLMKYSETLTGRVTYGVEAFARGLLVIPRILAQNSGFDVKDCEVKLLHE 645
G GA E+ L + ++ TL GR EAFA L VIPR LA+NSG D + +L E
Sbjct: 410 GGGAPEIEVALKIRDWAPTLGGREQLAAEAFASALEVIPRALAENSGLD----PIDILVE 465
Query: 646 IRKLLEANGNKITGEIALGLNLDSGEPMKPHDAGI 750
+RK E G+ G+++ SGE + G+
Sbjct: 466 LRKAHE------EGKTTYGVDVFSGEVACMKERGV 494
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,849,754
Number of Sequences: 369166
Number of extensions: 1465157
Number of successful extensions: 4127
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4003
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4086
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6873311200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)