Planarian EST Database


Dr_sW_011_M22

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_011_M22
         (567 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9BUL8|PDC10_HUMAN  Programmed cell death protein 10 (TF-...   135   5e-32
sp|Q8VE70|PDC10_MOUSE  Programmed cell death protein 10 (TF-...   135   7e-32
sp|Q6NX65|PDC10_RAT  Programmed cell death protein 10             135   7e-32
sp|Q8AVR4|PDC10_XENLA  Programmed cell death protein 10           135   9e-32
sp|Q6DF07|PDC10_XENTR  Programmed cell death protein 10           134   1e-31
sp|Q6PHH3|PDC10_BRARE  Programmed cell death protein 10           134   1e-31
sp|Q5ZIV5|PDC10_CHICK  Programmed cell death protein 10           134   2e-31
sp|O42649|SMC3_SCHPO  Structural maintenance of chromosome 3...    35   0.13 
sp|Q9Y446|PKP3_HUMAN  Plakophilin-3                                34   0.29 
sp|Q15075|EEA1_HUMAN  Early endosome antigen 1 (Endosome-ass...    33   0.49 
>sp|Q9BUL8|PDC10_HUMAN Programmed cell death protein 10 (TF-1 cell apoptosis-related
           protein 15) (Cerebral cavernous malformations 3 protein)
          Length = 212

 Score =  135 bits (341), Expect = 5e-32
 Identities = 78/176 (44%), Positives = 112/176 (63%)
 Frame = +3

Query: 39  VFEPVFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLR 218
           V  PVF +LE+ +LS   TL+ +F K E++ PG +Q+ ++ IL K  +E  V+ +E+ LR
Sbjct: 25  VMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVE--VNFTESLLR 82

Query: 219 MASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKNLL 398
           MA+      +    +  +  L  KA  LK++LS+IPDEI+DR  FL TIK+IASAIK LL
Sbjct: 83  MAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELL 142

Query: 399 DCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLL 566
           D V+ V        ++ +LE  K++FVKYSK FS+TLK +F+D K   V+ SAN L
Sbjct: 143 DTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRL 197
>sp|Q8VE70|PDC10_MOUSE Programmed cell death protein 10 (TF-1 cell apoptosis-related
           protein 15)
          Length = 212

 Score =  135 bits (340), Expect = 7e-32
 Identities = 78/176 (44%), Positives = 112/176 (63%)
 Frame = +3

Query: 39  VFEPVFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLR 218
           V  PVF +LE+ +LS   TL+ +F K E++ PG +Q+ ++ IL K  +E  V+ +E+ LR
Sbjct: 25  VMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVE--VNFTESLLR 82

Query: 219 MASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKNLL 398
           MA+      +    +  +  L  KA  LK++LS+IPDEI+DR  FL TIK+IASAIK LL
Sbjct: 83  MAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELL 142

Query: 399 DCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLL 566
           D V+ V        ++ +LE  K++FVKYSK FS+TLK +F+D K   V+ SAN L
Sbjct: 143 DTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFISANRL 197
>sp|Q6NX65|PDC10_RAT Programmed cell death protein 10
          Length = 210

 Score =  135 bits (340), Expect = 7e-32
 Identities = 78/176 (44%), Positives = 112/176 (63%)
 Frame = +3

Query: 39  VFEPVFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLR 218
           V  PVF +LE+ +LS   TL+ +F K E++ PG +Q+ ++ IL K  +E  V+ +E+ LR
Sbjct: 23  VMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVE--VNFTESLLR 80

Query: 219 MASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKNLL 398
           MA+      +    +  +  L  KA  LK++LS+IPDEI+DR  FL TIK+IASAIK LL
Sbjct: 81  MAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELL 140

Query: 399 DCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLL 566
           D V+ V        ++ +LE  K++FVKYSK FS+TLK +F+D K   V+ SAN L
Sbjct: 141 DTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFISANRL 195
>sp|Q8AVR4|PDC10_XENLA Programmed cell death protein 10
          Length = 212

 Score =  135 bits (339), Expect = 9e-32
 Identities = 78/176 (44%), Positives = 111/176 (63%)
 Frame = +3

Query: 39  VFEPVFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLR 218
           V  PVF +LE+ +LS   TL+ +F K E++ PG +Q+ +  IL K  +E  V+ +E+ LR
Sbjct: 25  VMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIITKILEKKSVE--VNFTESLLR 82

Query: 219 MASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKNLL 398
           MA+      +    +  +  L  KA  LK++LS+IPDEI+DR  FL TIK+IASAIK LL
Sbjct: 83  MAADDVEEYMVERPEPEFQELNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELL 142

Query: 399 DCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLL 566
           D V+ V        ++ +LE  K++FVKYSK FS+TLK +F+D K   V+ SAN L
Sbjct: 143 DTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKALNVFISANRL 197
>sp|Q6DF07|PDC10_XENTR Programmed cell death protein 10
          Length = 212

 Score =  134 bits (338), Expect = 1e-31
 Identities = 78/176 (44%), Positives = 110/176 (62%)
 Frame = +3

Query: 39  VFEPVFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLR 218
           V  PVF +LE  +LS   TL+ +F K E++ PG +Q+ +  IL K  +E  V+ +E+ LR
Sbjct: 25  VMYPVFNELEHVNLSAAQTLRAAFIKAEKENPGLTQDIITKILEKKSVE--VNFTESLLR 82

Query: 219 MASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKNLL 398
           MA+      +    +  +  L  KA  LK++LS+IPDEI+DR  FL TIK+IASAIK LL
Sbjct: 83  MAADDVEEYMVERPEPEFQELNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELL 142

Query: 399 DCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLL 566
           D V+ V        ++ +LE  K++FVKYSK FS+TLK +F+D K   V+ SAN L
Sbjct: 143 DTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKALNVFISANRL 197
>sp|Q6PHH3|PDC10_BRARE Programmed cell death protein 10
          Length = 205

 Score =  134 bits (338), Expect = 1e-31
 Identities = 76/176 (43%), Positives = 114/176 (64%)
 Frame = +3

Query: 39  VFEPVFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLR 218
           V  PVF +LE  +LS   TL+ +F K E++ PG +Q+ ++ IL K  +E  ++ +E+ LR
Sbjct: 18  VMYPVFNELESVNLSAAQTLRAAFKKAEKENPGLTQDIIMKILEKKNVE--INFTESLLR 75

Query: 219 MASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKNLL 398
           MA+      + +  ++ +  L  +A  LK++LS+IPDEI+DR  FL TIK+IASAIK LL
Sbjct: 76  MAADDVEEYMIDRPEREFQDLNERARALKQILSKIPDEINDRVRFLQTIKDIASAIKELL 135

Query: 399 DCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLL 566
           D V+ V        ++ +LE  K++FVK+SK FS+TLK +F+D K   V+ASAN L
Sbjct: 136 DTVNNVFKKYQYQ-NRRALEHQKKEFVKHSKSFSDTLKTYFKDGKAINVFASANRL 190
>sp|Q5ZIV5|PDC10_CHICK Programmed cell death protein 10
          Length = 212

 Score =  134 bits (337), Expect = 2e-31
 Identities = 77/176 (43%), Positives = 112/176 (63%)
 Frame = +3

Query: 39  VFEPVFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLR 218
           V  PVF +LE+ +LS   TL+ +F K E++ PG +Q+ ++ IL K  ++  V+ +E+ LR
Sbjct: 25  VMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVD--VNFTESLLR 82

Query: 219 MASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKNLL 398
           MA+      +    +  +  L  KA  LK++LS+IPDEI+DR  FL TIK+IASAIK LL
Sbjct: 83  MAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELL 142

Query: 399 DCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLL 566
           D V+ V        ++ +LE  K++FVKYSK FS+TLK +F+D K   V+ SAN L
Sbjct: 143 DTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFISANRL 197
>sp|O42649|SMC3_SCHPO Structural maintenance of chromosome 3 (Cohesin complex Psm3 subunit)
          Length = 1194

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 2/113 (1%)
 Frame = +3

Query: 171  KLGLENEVDMSETFLRMASMAETGVVRNMRKQIYNL--LESKAHTLKEVLSRIPDEISDR 344
            ++G +N +D SE            V R++ K    L  ++S +  L+E + RI  EISD+
Sbjct: 835  EIGSDNRIDESEL---------NSVKRSLLKYENKLQIIKSSSSGLEEQMQRINSEISDK 885

Query: 345  RSFLDTIKEIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSN 503
            R+ L++++E+            EV T +  D        AKR  +   K+  N
Sbjct: 886  RNELESLEELQ----------HEVATRIEQDAKINERNAAKRSLLLARKKECN 928
>sp|Q9Y446|PKP3_HUMAN Plakophilin-3
          Length = 797

 Score = 33.9 bits (76), Expect = 0.29
 Identities = 23/122 (18%), Positives = 55/122 (45%), Gaps = 6/122 (4%)
 Frame = +3

Query: 51  VFEKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENE------VDMSETF 212
           ++ +L Q+   + HT + +   ++    G  +    G+L++L LE E      +D   T 
Sbjct: 610 LYNRLLQRCELNRHTTEAAAGALQNITAGDRR--WAGVLSRLALEQERILNPLLDRVRTA 667

Query: 213 LRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIKEIASAIKN 392
                 + TG++RN+ +   N  E     +  ++ ++P  + ++    + +  I + + N
Sbjct: 668 DHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNN 727

Query: 393 LL 398
           L+
Sbjct: 728 LV 729
>sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-associated protein p162) (Zinc
            finger FYVE domain-containing protein 2)
          Length = 1411

 Score = 33.1 bits (74), Expect = 0.49
 Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 1/136 (0%)
 Frame = +3

Query: 57   EKLEQKSLSHTHTLKQSFAKVEQQYPGFSQNFLIGILNKLGLENEVDMSETFLRMASMAE 236
            EK EQ+   + + LKQS  + ++Q         I +L K  LEN++    T       AE
Sbjct: 951  EKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAE 1010

Query: 237  TGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRS-FLDTIKEIASAIKNLLDCVSE 413
                    K+  ++L++     +E   ++  +   R S  L T +++ S  + L     +
Sbjct: 1011 --------KEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQED 1062

Query: 414  VITHLPTDGHKTSLEQ 461
            +I++    G++  L Q
Sbjct: 1063 LISNRNQIGNQNKLIQ 1078
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,557,459
Number of Sequences: 369166
Number of extensions: 1306831
Number of successful extensions: 3511
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3416
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3490
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4127973360
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)