Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_L15
(659 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O02649|CH60_DROME 60 kDa heat shock protein, mitochondri... 320 2e-87
sp|P18687|CH60_CRIGR 60 kDa heat shock protein, mitochondri... 316 3e-86
sp|P10809|CH60_HUMAN 60 kDa heat shock protein, mitochondri... 316 4e-86
sp|P63039|CH60_RAT 60 kDa heat shock protein, mitochondrial... 315 7e-86
sp|Q5NVM5|CH60_PONPY 60 kDa heat shock protein, mitochondri... 314 1e-85
sp|Q9VMN5|CH60C_DROME Probable 60 kDa heat shock protein ho... 306 3e-83
sp|P50140|CH60_CAEEL Chaperonin homolog HSP60, mitochondria... 297 1e-80
sp|P25420|CH63_HELVI 63 kDa chaperonin, mitochondrial precu... 266 4e-71
sp|O74261|HSP60_CANAL Heat shock protein 60, mitochondrial ... 260 2e-69
sp|P19882|HSP60_YEAST Heat shock protein 60, mitochondrial ... 251 9e-67
>sp|O02649|CH60_DROME 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1)
Length = 573
Score = 320 bits (820), Expect = 2e-87
Identities = 156/218 (71%), Positives = 194/218 (88%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD++IG+LISEAMKKVG+DG ITVKDGKTL DELEVIEGMKFDRGYISPY
Sbjct: 164 IAQVATISANGDQAIGNLISEAMKKVGRDGVITVKDGKTLTDELEVIEGMKFDRGYISPY 223
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FIN+ KGAK EFQDA +L SEKKISS+QS+IP LE+ + Q+KPL+I+AED+DGEAL+ LV
Sbjct: 224 FINSSKGAKVEFQDALLLLSEKKISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTLV 283
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
+NRLK+GLQV AVKAPGFGDNRK+TL DMA ++GGIVFGD+AD K+E+V++ DLG+ E
Sbjct: 284 VNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGE 343
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
++ITKDDTL++KGKG + D+ +R ++I+D+I +TSEY
Sbjct: 344 VVITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEY 381
>sp|P18687|CH60_CRIGR 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1)
Length = 573
Score = 316 bits (810), Expect = 3e-86
Identities = 150/218 (68%), Positives = 188/218 (86%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD+ IG++IS+AMKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPY
Sbjct: 168 IAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPY 227
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FINT KG KCEFQDA++L SEKKISS+QS++P LE+ + +KPL+I+AEDVDGEAL+ LV
Sbjct: 228 FINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLV 287
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
LNRLK+GLQV AVKAPGFGDNRKN L+DMA +TGG VFG+E +E+VQ HDLG+ E
Sbjct: 288 LNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGE 347
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
+++TKDD +++KGKG + I+KRI EI +++ ++TSEY
Sbjct: 348 VIVTKDDAMLLKGKGEKAQIEKRIQEITEQLEITTSEY 385
>sp|P10809|CH60_HUMAN 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1) (P60 lymphocyte
protein) (HuCHA60)
Length = 573
Score = 316 bits (809), Expect = 4e-86
Identities = 152/218 (69%), Positives = 189/218 (86%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD+ IG++IS+AMKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPY
Sbjct: 168 IAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPY 227
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FINT KG KCEFQDA++L SEKKISSIQS++P LE+ + +KPL+I+AEDVDGEAL+ LV
Sbjct: 228 FINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLV 287
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
LNRLK+GLQV AVKAPGFGDNRKN L+DMA +TGG VFG+E T +E+VQ HDLG+ E
Sbjct: 288 LNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGE 347
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
+++TKDD +++KGKG + I+KRI EI +++ ++TSEY
Sbjct: 348 VIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEY 385
>sp|P63039|CH60_RAT 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1) (HSP-65)
sp|P63038|CH60_MOUSE 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
(Mitochondrial matrix protein P1) (HSP-65)
Length = 573
Score = 315 bits (807), Expect = 7e-86
Identities = 150/218 (68%), Positives = 188/218 (86%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD+ IG++IS+AMKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPY
Sbjct: 168 IAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPY 227
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FINT KG KCEFQDA++L SEKKISS+QS++P LE+ + +KPL+I+AEDVDGEAL+ LV
Sbjct: 228 FINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLV 287
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
LNRLK+GLQV AVKAPGFGDNRKN L+DMA +TGG VFG+E +E+VQ HDLG+ E
Sbjct: 288 LNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGE 347
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
+++TKDD +++KGKG + I+KRI EI +++ ++TSEY
Sbjct: 348 VIVTKDDAMLLKGKGDKAHIEKRIQEITEQLDITTSEY 385
>sp|Q5NVM5|CH60_PONPY 60 kDa heat shock protein, mitochondrial precursor (Hsp60) (60 kDa
chaperonin) (CPN60) (Heat shock protein 60) (HSP-60)
Length = 573
Score = 314 bits (804), Expect = 1e-85
Identities = 150/218 (68%), Positives = 189/218 (86%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD+ IG++IS+AMKKVG+ G ITVKDGKTL+DELE+IEGMKFDRGYISPY
Sbjct: 168 IAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPY 227
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FINT KG KCEFQDA++L SEKKISS+QS++P LE+ + +KPL+I+AEDVDGEAL+ LV
Sbjct: 228 FINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLV 287
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
LNRLK+GLQV AVKAPGFGDNRKN L+DMA +TGG VFG+E T +E+VQ HDLG+ E
Sbjct: 288 LNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGE 347
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
+++TKDD ++++GKG + I+KRI EI +++ ++TSEY
Sbjct: 348 VIVTKDDAMLLEGKGDKAQIEKRIQEIIEQLDVTTSEY 385
>sp|Q9VMN5|CH60C_DROME Probable 60 kDa heat shock protein homolog 2, mitochondrial
precursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat
shock protein 60) (HSP-60)
Length = 576
Score = 306 bits (784), Expect = 3e-83
Identities = 145/218 (66%), Positives = 186/218 (85%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
I QVATISANGD+S+G+LISEA+KKVG+DG ITVKDGKTL DELEVIEGMKFDRGYISPY
Sbjct: 168 ICQVATISANGDKSVGNLISEAIKKVGRDGVITVKDGKTLCDELEVIEGMKFDRGYISPY 227
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FINT KGAK EFQDA +LF EKKI S S++P LE+ + Q+KPL+I+AED++ EAL+ LV
Sbjct: 228 FINTSKGAKVEFQDALLLFCEKKIKSAPSIVPALELANAQRKPLVIIAEDLEAEALSTLV 287
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
+NRLK+GLQVCAVKAPGFGDNRK L DMA +TGGIVFGDEA+ ++E++++ D GR E
Sbjct: 288 VNRLKVGLQVCAVKAPGFGDNRKENLMDMAVATGGIVFGDEANMVRLEDIKMSDFGRVGE 347
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
++++KDDT+++KGKG + +++KR++ +R+ I STS Y
Sbjct: 348 VVVSKDDTMLLKGKGQKAEVEKRVEGLREAIKESTSSY 385
>sp|P50140|CH60_CAEEL Chaperonin homolog HSP60, mitochondrial precursor (Heat shock
protein 60) (HSP-60)
Length = 568
Score = 297 bits (761), Expect = 1e-80
Identities = 143/218 (65%), Positives = 182/218 (83%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD +G+LIS+AMKKVG G ITVKDGKTL+DELE+IEGMKFDRGYISPY
Sbjct: 159 IAQVATISANGDTVVGNLISDAMKKVGTTGVITVKDGKTLNDELELIEGMKFDRGYISPY 218
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FI + KGAK E++ A +L SEKKIS +Q ++P LE+ ++ ++PL+I+AEDVDGEALT LV
Sbjct: 219 FITSAKGAKVEYEKALVLLSEKKISQVQDIVPALELANKLRRPLVIIAEDVDGEALTTLV 278
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
LNRLK+GLQV A+KAPGFGDNRKNTL+DM +TG +FGD+++ KIE++ +DLG E
Sbjct: 279 LNRLKVGLQVVAIKAPGFGDNRKNTLKDMGIATGATIFGDDSNLIKIEDITANDLGEVDE 338
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
+ ITKDDTL+++G+G Q +I+KRI+ I DEI STS+Y
Sbjct: 339 VTITKDDTLLLRGRGDQTEIEKRIEHITDEIEQSTSDY 376
>sp|P25420|CH63_HELVI 63 kDa chaperonin, mitochondrial precursor (p63)
Length = 569
Score = 266 bits (680), Expect = 4e-71
Identities = 130/218 (59%), Positives = 170/218 (77%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
I QVATISANGD SIG LI+ AM +VGK+G ITVKDGKTL DELE+IEGMKFDRGY+SPY
Sbjct: 171 IEQVATISANGDESIGKLIAAAMNRVGKNGVITVKDGKTLEDELEIIEGMKFDRGYVSPY 230
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FIN++KG K E+ DA +L+SEKKI ++P LE+ + QKKPL+I+AED DGE L+ LV
Sbjct: 231 FINSNKGPKVEYNDALVLYSEKKIYYASQVVPALELANSQKKPLVIIAEDYDGEPLSVLV 290
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
+N+LK+GL V AVKAPGFG+ R N L DMA +TGG VF D+ + ++E+ Q G+ E
Sbjct: 291 VNKLKIGLPVVAVKAPGFGEYRTNALLDMAAATGG-VFEDDTNLVRLEDCQAESFGQVGE 349
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTSEY 659
++ITKD TL++KGKG +I++RID+I++E+ +TS Y
Sbjct: 350 VIITKDSTLLLKGKGDPNEIKQRIDQIKEELETATSNY 387
>sp|O74261|HSP60_CANAL Heat shock protein 60, mitochondrial precursor (60 kDa chaperonin)
(Protein Cpn60)
Length = 566
Score = 260 bits (665), Expect = 2e-69
Identities = 133/219 (60%), Positives = 172/219 (78%), Gaps = 1/219 (0%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD+ IGDL++ AM+KVGK+G ITVK+GKTL DELEV EGMKFDRG+ISPY
Sbjct: 160 IAQVATISANGDKHIGDLLANAMEKVGKEGVITVKEGKTLEDELEVTEGMKFDRGFISPY 219
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FI K K EF++ IL SEKKISSIQ ++P LE+++Q ++PLLI+AEDVDGEAL A +
Sbjct: 220 FITNTKTGKVEFENPLILLSEKKISSIQDILPSLELSNQTRRPLLIIAEDVDGEALAACI 279
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
LN+L+ +QVCAVKAPGFGDNRKNTL D+A +GG VF +E D K EN + LG A
Sbjct: 280 LNKLRGQVQVCAVKAPGFGDNRKNTLGDIAILSGGTVFTEELD-IKPENATIEQLGSAGA 338
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIA-LSTSEY 659
+ ITK+DT+++ G+G + +++ R ++IR IA + T+EY
Sbjct: 339 VTITKEDTVLLNGEGSKDNLEARCEQIRSVIADVHTTEY 377
>sp|P19882|HSP60_YEAST Heat shock protein 60, mitochondrial precursor (Stimulator factor I
66 kDa component) (P66) (CPN60)
Length = 572
Score = 251 bits (642), Expect = 9e-67
Identities = 122/216 (56%), Positives = 168/216 (77%)
Frame = +3
Query: 6 IAQVATISANGDRSIGDLISEAMKKVGKDGTITVKDGKTLHDELEVIEGMKFDRGYISPY 185
IAQVATISANGD +G L++ AM+KVGK+G IT+++G+TL DELEV EGM+FDRG+ISPY
Sbjct: 165 IAQVATISANGDSHVGKLLASAMEKVGKEGVITIREGRTLEDELEVTEGMRFDRGFISPY 224
Query: 186 FINTDKGAKCEFQDAFILFSEKKISSIQSLIPVLEMTHQQKKPLLIVAEDVDGEALTALV 365
FI K +K EF+ +L SEKKISSIQ ++P LE+++Q ++PLLI+AEDVDGEAL A +
Sbjct: 225 FITDPKSSKVEFEKPLLLLSEKKISSIQDILPALEISNQSRRPLLIIAEDVDGEALAACI 284
Query: 366 LNRLKLGLQVCAVKAPGFGDNRKNTLRDMATSTGGIVFGDEADTYKIENVQLHDLGRAQE 545
LN+L+ ++VCAVKAPGFGDNRKNT+ D+A TGG VF +E D K E + +LG
Sbjct: 285 LNKLRGQVKVCAVKAPGFGDNRKNTIGDIAVLTGGTVFTEELD-LKPEQCTIENLGSCDS 343
Query: 546 ILITKDDTLVMKGKGLQKDIQKRIDEIRDEIALSTS 653
I +TK+DT+++ G G ++ IQ+RI++I+ I ++T+
Sbjct: 344 ITVTKEDTVILNGSGPKEAIQERIEQIKGSIDITTT 379
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,633,126
Number of Sequences: 369166
Number of extensions: 1386789
Number of successful extensions: 4975
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4569
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4683
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5511356910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)