Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_L09
(854 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BJ64|CHDH_MOUSE Choline dehydrogenase, mitochondrial p... 239 5e-63
sp|Q8NE62|CHDH_HUMAN Choline dehydrogenase, mitochondrial p... 234 2e-61
sp|Q985M5|BETA_RHILO Choline dehydrogenase (CHD) (CDH) 223 7e-58
sp|Q8G1Z8|BETA_BRUSU Choline dehydrogenase (CHD) (CDH) 214 2e-55
sp|Q8YFY2|BETA_BRUME Choline dehydrogenase (CHD) (CDH) 212 1e-54
sp|Q8X6C6|BETA_ECO57 Choline dehydrogenase (CHD) (CDH) 200 5e-51
sp|Q8UH55|BETA_AGRT5 Choline dehydrogenase (CHD) (CDH) 198 1e-50
sp|P17444|BETA_ECOLI Choline dehydrogenase (CHD) (CDH) 198 2e-50
sp|Q8FKI9|BETA_ECOL6 Choline dehydrogenase (CHD) (CDH) 198 2e-50
sp|Q88CW6|BETA_PSEPK Choline dehydrogenase (CHD) (CDH) 196 7e-50
>sp|Q8BJ64|CHDH_MOUSE Choline dehydrogenase, mitochondrial precursor (CHD) (CDH)
Length = 596
Score = 239 bits (611), Expect = 5e-63
Identities = 119/229 (51%), Positives = 158/229 (68%)
Frame = +1
Query: 16 EWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQVIVSQ 195
EW +G G T HL +G FIRS V HPDIQFHF PS ++DHGR+ + +YQV V
Sbjct: 369 EWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRKPTQQEAYQVHVGT 428
Query: 196 MRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFRGEEF 375
MR+ S G + L+S +PR HP+ PNY S E D + + ++L+REI Q A FRG+E
Sbjct: 429 MRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKEL 488
Query: 376 SPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRVVDAS 555
PG +Q+DK++D F++ + YHP+ TCKMG +SD + VVD+Q +V+GV+NLRVVDAS
Sbjct: 489 QPGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDAS 548
Query: 556 VMPSIVSGNTNAPTMMIAEKAADMILGKTPLPKLNGVPVWKPKHPNNQR 702
+MPS+VSGN NAPT+MIAEKAAD+I G L N VPV+KP+ + QR
Sbjct: 549 IMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKN-VPVYKPQTLDTQR 596
>sp|Q8NE62|CHDH_HUMAN Choline dehydrogenase, mitochondrial precursor (CHD) (CDH)
Length = 594
Score = 234 bits (598), Expect = 2e-61
Identities = 120/229 (52%), Positives = 153/229 (66%)
Frame = +1
Query: 16 EWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQVIVSQ 195
EW +G G T HL +G FIRS+ V HPDIQFHF PS ++DHGR + +YQV V
Sbjct: 367 EWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHGRVPTQQEAYQVHVGP 426
Query: 196 MRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFRGEEF 375
MR S G + L+S +P+ HP+ PNY S E D + + +KL REI Q A FRG+E
Sbjct: 427 MRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRGKEL 486
Query: 376 SPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRVVDAS 555
PG IQ+DK++D F++ + YHP+ TCKMG SD + VVD Q RV+GV+NLRVVDAS
Sbjct: 487 QPGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDAS 546
Query: 556 VMPSIVSGNTNAPTMMIAEKAADMILGKTPLPKLNGVPVWKPKHPNNQR 702
+MPS+VSGN NAPT+MIAEKAAD+I G+ L VPV+KP+ QR
Sbjct: 547 IMPSMVSGNLNAPTIMIAEKAADIIKGQPALWD-KDVPVYKPRTLATQR 594
>sp|Q985M5|BETA_RHILO Choline dehydrogenase (CHD) (CDH)
Length = 550
Score = 223 bits (567), Expect = 7e-58
Identities = 108/226 (47%), Positives = 147/226 (65%)
Frame = +1
Query: 7 VDKEWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQVI 186
+ +W KSG G T H + AF+RS A V +PDIQ+HF P+ + G+ A H +Q
Sbjct: 319 IGAQWLFFKSGLGATNHFEAAAFVRSRAGVDYPDIQYHFIPAAVRYDGKAAAKSHGFQAH 378
Query: 187 VSQMRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFRG 366
V MRS+S+GSV+L+S DP+ P+ NY S D+ E + I+L REI QSAFD FRG
Sbjct: 379 VGPMRSKSRGSVTLRSPDPKAKPVIRFNYMSHPDDWTEFRHCIRLTREIFGQSAFDAFRG 438
Query: 367 EEFSPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRVV 546
+E SPG +Q+D +D+FI++ E YHP TCKMG D ++VVD +CRV+GVD LRV
Sbjct: 439 QEISPGSHVQSDDDLDVFIRDHAESAYHPCGTCKMGRADDVTSVVDPECRVIGVDGLRVA 498
Query: 547 DASVMPSIVSGNTNAPTMMIAEKAADMILGKTPLPKLNGVPVWKPK 684
D+S+ P + +GN NAP++M EKA+D ILG+TPL N P P+
Sbjct: 499 DSSIFPRVTNGNLNAPSIMTGEKASDHILGRTPLAPSNQEPWINPR 544
>sp|Q8G1Z8|BETA_BRUSU Choline dehydrogenase (CHD) (CDH)
Length = 549
Score = 214 bits (546), Expect = 2e-55
Identities = 104/227 (45%), Positives = 146/227 (64%)
Frame = +1
Query: 4 QVDKEWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQV 183
++ EW K+G G T H S AF+RS+A V +PDIQ+HF P + G+ A H +Q
Sbjct: 317 RIGVEWLLFKTGDGATNHFESAAFVRSKAGVEYPDIQYHFLPVAIRYDGKAAAQSHGFQA 376
Query: 184 IVSQMRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFR 363
V MRS+S+GSV+L+S +PR P+ NY S E D+ + + ++L REI Q+AFD +R
Sbjct: 377 HVGPMRSKSRGSVTLRSANpreKPVIKFNYMSHEDDWADFRHCVRLTREIFGQAAFDPYR 436
Query: 364 GEEFSPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRV 543
G E PG +QTD ++D FI+ E +HP TCKMG+ D VVD +CRV+GV+ LRV
Sbjct: 437 GAEIQPGAHVQTDDEIDNFIREHVESAFHPCGTCKMGAVDDPMAVVDPECRVIGVEGLRV 496
Query: 544 VDASVMPSIVSGNTNAPTMMIAEKAADMILGKTPLPKLNGVPVWKPK 684
D+S+ P I +GN N P++M+ EKA+D ILG+TPL + N P P+
Sbjct: 497 ADSSIFPRITNGNLNGPSIMVGEKASDHILGRTPLARSNQEPWINPR 543
>sp|Q8YFY2|BETA_BRUME Choline dehydrogenase (CHD) (CDH)
Length = 549
Score = 212 bits (539), Expect = 1e-54
Identities = 103/227 (45%), Positives = 145/227 (63%)
Frame = +1
Query: 4 QVDKEWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQV 183
++ EW K+G G T H S AF+RS+A V +PDIQ+HF P + G+ A H +Q
Sbjct: 317 RIGVEWLLFKTGDGATNHFESAAFVRSKAGVEYPDIQYHFLPVAIRYDGKAAAQSHGFQA 376
Query: 184 IVSQMRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFR 363
V MRS+S+GSV+L+S +PR P+ NY S E D+ + + ++L REI Q+AFD +R
Sbjct: 377 HVGPMRSKSRGSVTLRSANpreKPVIKFNYMSHEDDWADFRHCVRLTREIFGQAAFDPYR 436
Query: 364 GEEFSPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRV 543
G E PG +QTD ++D FI+ E +HP TCKMG+ D VVD +CRV+GV+ LRV
Sbjct: 437 GAEIQPGAHVQTDDEIDNFIREHVESAFHPCGTCKMGAVDDPMAVVDPECRVIGVEGLRV 496
Query: 544 VDASVMPSIVSGNTNAPTMMIAEKAADMILGKTPLPKLNGVPVWKPK 684
D+S+ P I +GN N P++M+ EKA+ ILG+TPL + N P P+
Sbjct: 497 ADSSIFPRITNGNLNGPSIMVGEKASGHILGRTPLARSNQEPWINPR 543
>sp|Q8X6C6|BETA_ECO57 Choline dehydrogenase (CHD) (CDH)
Length = 562
Score = 200 bits (508), Expect = 5e-51
Identities = 104/230 (45%), Positives = 142/230 (61%), Gaps = 7/230 (3%)
Frame = +1
Query: 4 QVDKEWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQV 183
++ EW +G G + H +G FIRS + P+IQ+HF P + +G EH +Q
Sbjct: 325 KIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQC 384
Query: 184 IVSQMRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFR 363
V MRS S+G V ++S DP HP NY S E+D+ E + I++ REI+ Q A D++R
Sbjct: 385 HVGSMRSPSRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYR 444
Query: 364 GEEFSPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRV 543
G E SPG + QTD+Q+D F++N E +HP TCKMG D +VVD + RV G++ LRV
Sbjct: 445 GREISPGTECQTDEQLDEFVRNHAETAFHPCGTCKMG--YDEMSVVDGEGRVHGLEGLRV 502
Query: 544 VDASVMPSIVSGNTNAPTMMIAEKAADMILGKTPLPK-------LNGVPV 672
VDAS+MP I++GN NA T+MI EK ADMI GK LP+ NG+PV
Sbjct: 503 VDASIMPQIITGNLNATTIMIGEKMADMIRGKEALPRSTAGYFVANGMPV 552
>sp|Q8UH55|BETA_AGRT5 Choline dehydrogenase (CHD) (CDH)
Length = 549
Score = 198 bits (504), Expect = 1e-50
Identities = 97/223 (43%), Positives = 137/223 (61%)
Frame = +1
Query: 16 EWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQVIVSQ 195
+W K G G + + AF+RS + PDIQ+HF P + G+ A H +Q V
Sbjct: 321 QWLLSKGGLGASNQFEACAFLRSAPGLKQPDIQYHFLPVAISYDGKAAAKSHGFQAHVGY 380
Query: 196 MRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFRGEEF 375
S+S+G+V+L+S DP P+ NY S D+ + + ++L REI Q AFD+FRG E
Sbjct: 381 NLSKSRGNVTLRSADPHDDPVIRFNYMSHPEDWEKFRHCVRLTREIFGQKAFDDFRGPEI 440
Query: 376 SPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRVVDAS 555
PG++I+TD+Q+D F++ E YHP TC+MG +D VVD +CRV+GV+ LRV D+S
Sbjct: 441 QPGENIETDEQIDAFLREHLESAYHPCGTCRMGDRNDPMAVVDPECRVIGVEGLRVADSS 500
Query: 556 VMPSIVSGNTNAPTMMIAEKAADMILGKTPLPKLNGVPVWKPK 684
+ P + GN N P++M EKAAD ILGKTPLP+ N P P+
Sbjct: 501 IFPHVTYGNLNGPSIMTGEKAADHILGKTPLPRSNQEPWVNPR 543
>sp|P17444|BETA_ECOLI Choline dehydrogenase (CHD) (CDH)
Length = 556
Score = 198 bits (503), Expect = 2e-50
Identities = 103/230 (44%), Positives = 142/230 (61%), Gaps = 7/230 (3%)
Frame = +1
Query: 4 QVDKEWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQV 183
++ EW +G G + H +G FIRS + P+IQ+HF P + +G EH +Q
Sbjct: 325 KIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQC 384
Query: 184 IVSQMRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFR 363
V MRS S+G V ++S DP HP NY S E+D+ E + I++ REI+ Q A D++R
Sbjct: 385 HVGSMRSPSRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYR 444
Query: 364 GEEFSPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRV 543
G E SPG + QTD+Q+D F++N E +HP TCKMG D +VVD + RV G++ LRV
Sbjct: 445 GREISPGVECQTDEQLDEFVRNHAETAFHPCGTCKMG--YDEMSVVDGEGRVHGLEGLRV 502
Query: 544 VDASVMPSIVSGNTNAPTMMIAEKAADMILGKTPLPK-------LNGVPV 672
VDAS+MP I++GN NA T+MI EK ADMI G+ LP+ NG+PV
Sbjct: 503 VDASIMPQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPV 552
>sp|Q8FKI9|BETA_ECOL6 Choline dehydrogenase (CHD) (CDH)
Length = 556
Score = 198 bits (503), Expect = 2e-50
Identities = 104/230 (45%), Positives = 141/230 (61%), Gaps = 7/230 (3%)
Frame = +1
Query: 4 QVDKEWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQV 183
++ EW +G G + H +G FIRS + P+IQ+HF P + +G EH +Q
Sbjct: 325 RIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQC 384
Query: 184 IVSQMRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFR 363
V MRS S+G V ++S DP HP NY S E+D+ E + I++ REI+ Q A D++R
Sbjct: 385 HVGSMRSPSRGHVRIKSRDPHQHPGILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYR 444
Query: 364 GEEFSPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRV 543
G E SPG + QTD+Q+D F++N E +HP TCKMG D VVD + RV G++ LRV
Sbjct: 445 GREISPGVECQTDEQLDEFVRNHAETAFHPCGTCKMG--YDEMAVVDGEGRVHGLEGLRV 502
Query: 544 VDASVMPSIVSGNTNAPTMMIAEKAADMILGKTPLPK-------LNGVPV 672
VDAS+MP I++GN NA T+MI EK ADMI GK LP+ NG+PV
Sbjct: 503 VDASIMPQIITGNLNATTIMIGEKIADMIRGKEALPRSTAGYFVANGMPV 552
>sp|Q88CW6|BETA_PSEPK Choline dehydrogenase (CHD) (CDH)
Length = 565
Score = 196 bits (498), Expect = 7e-50
Identities = 97/216 (44%), Positives = 139/216 (64%)
Frame = +1
Query: 7 VDKEWDEHKSGWGTTVHLTSGAFIRSEAKVHHPDIQFHFFPSLLLDHGRQEASEHSYQVI 186
+ EW + +G G + +G FIR+ + P+IQ+HF P + +G EH +Q
Sbjct: 328 IGAEWMFNGTGIGASNQFEAGGFIRTRPEFKWPNIQYHFLPVAINYNGSNGVKEHGFQAH 387
Query: 187 VSQMRSQSKGSVSLQSYDPRVHPIYDPNYCSLERDFWELKAGIKLAREILFQSAFDEFRG 366
+ MRS ++G + ++S DPR HP NY S E+D+ E + GI+L REI+ Q A D +RG
Sbjct: 388 MGSMRSPARGRIQVKSKDPRQHPSILFNYMSTEQDWQEFRDGIRLTREIMAQPALDPYRG 447
Query: 367 EEFSPGKDIQTDKQMDLFIKNFGEHIYHPTSTCKMGSTSDNSTVVDSQCRVVGVDNLRVV 546
E SPG D+QTD+Q+D FI+ E +HP+ +CKMG +D+ VVD + RV G+ LRVV
Sbjct: 448 REISPGADVQTDEQLDKFIREHAETAFHPSCSCKMG--TDDMAVVDGEGRVHGMKGLRVV 505
Query: 547 DASVMPSIVSGNTNAPTMMIAEKAADMILGKTPLPK 654
DAS+MP I++GN NA T+MIAEK +D I G+ PLP+
Sbjct: 506 DASIMPLIITGNLNATTIMIAEKISDKIRGRKPLPR 541
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,211,161
Number of Sequences: 369166
Number of extensions: 1980346
Number of successful extensions: 5651
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5333
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5624
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)