Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_K19
(892 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q11073|YT45_CAEEL Hypothetical protein B0416.5 in chromo... 131 3e-30
sp|P60815|FLVC2_RAT Feline leukemia virus subgroup C recept... 102 1e-21
sp|Q91X85|FLVC2_MOUSE Feline leukemia virus subgroup C rece... 101 3e-21
sp|Q9UPI3|FLVC2_HUMAN Feline leukemia virus subgroup C rece... 99 2e-20
sp|Q9Y5Y0|FLVC1_HUMAN Feline leukemia virus subgroup C rece... 94 4e-19
sp|Q9N1F2|FLVC1_FELCA Feline leukemia virus subgroup C rece... 91 3e-18
sp|Q9ES43|FLVC1_MUSDU Feline leukemia virus subgroup C rece... 91 4e-18
sp|O01735|YC91_CAEEL Hypothetical transporter C09D4.1 88 3e-17
sp|P38298|YPC1_YEAST Alkaline ceramidase YPC1 36 0.13
sp|P76470|YFAV_ECOLI Inner membrane transport protein yfaV 35 0.22
>sp|Q11073|YT45_CAEEL Hypothetical protein B0416.5 in chromosome X
Length = 507
Score = 131 bits (329), Expect = 3e-30
Identities = 78/275 (28%), Positives = 128/275 (46%), Gaps = 3/275 (1%)
Frame = +1
Query: 4 TNGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCIL 183
TN + WI YA + + + Y +LS+V+ + TI +G+ +W +GLR ++
Sbjct: 58 TNTMSWIGYAPSGNYVNSFYGESSAA--WLSMVYMMCTIPVGMFAMWAGREWGLRTAVLI 115
Query: 184 CGWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQR 363
GW N + AV+R++ S +V + R+ I M GQ + +IA P MF P K+A WFP QR
Sbjct: 116 AGWANGIGAVIRVISSLDFVPQDLRFPICMTGQGIAAIAYPFIMFLPTKVAGSWFPDTQR 175
Query: 364 ALATTIGAMGNPVGILLGSLLPPFLI---EYTMFNXXXXXXXXXXXXXXXPTLXXXXXXX 534
A+AT+IG M NP+G+L+ +L+ P ++ E+ ++ T
Sbjct: 176 AIATSIGVMSNPLGVLMANLISPAIVKSPEHVIW-LNIFTCVPSLIAMLIATFGVNRSEP 234
Query: 535 XXXXXXXXDRPLDGVTFPEQLRRCLRNLSFLILSITFGMGLGLFTALSTLFEQIFCPFGY 714
+P + F ++ C + ++IL I G G+G+F L T+ ++ CP GY
Sbjct: 235 KIPPTFSASKP--QMDFVSGMKSCFSSKQYIILLIVMGGGIGMFNCLYTVMLELLCPSGY 292
Query: 715 PDTXXXXXXXXXXXXXXXXXXXXXXXXDRTKAFSE 819
+ DRTK + E
Sbjct: 293 SNFFSGVCAALMIVGGVFGAAASSIFVDRTKLYEE 327
>sp|P60815|FLVC2_RAT Feline leukemia virus subgroup C receptor-related protein 2
(Calcium-chelate transporter) (CCT)
Length = 546
Score = 102 bits (254), Expect = 1e-21
Identities = 67/242 (27%), Positives = 115/242 (47%), Gaps = 12/242 (4%)
Frame = +1
Query: 7 NGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCILC 186
N WI Y S+++ + Y V I++LS+ + + I L LPV W ++ FGLR I
Sbjct: 115 NAFQWIQYGSINNIFMNFYGVSAFAIDWLSMCYMLTYIPLLLPVAWMLEKFGLRTIAITG 174
Query: 187 GWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQRA 366
LN L A ++L + ++ + + M GQV+ S+AQ + P+++AS+WF +N+ +
Sbjct: 175 SALNCLGAWVKLGSLEPHL-----FPVTMVGQVICSVAQVFILGMPSRIASVWFGANEVS 229
Query: 367 LATTIGAMGNPVGILLGSLLPPFLI------EYTMFNXXXXXXXXXXXXXXXPTLXXXXX 528
A ++ GN +GI +G L+PP L+ E ++ L
Sbjct: 230 TACSMAVFGNQLGIAIGFLVPPVLVPNIKDQEKLAYHISIMFYIIGGVATLLFILVIIVF 289
Query: 529 XXXXXXXXXXDRPLD------GVTFPEQLRRCLRNLSFLILSITFGMGLGLFTALSTLFE 690
+ L ++ + R +NL+F++L IT+G+ G F ALSTL
Sbjct: 290 KEKPKYPPSRAQSLSYALATTDASYLSSIVRLFKNLNFVLLVITYGLNAGAFYALSTLLN 349
Query: 691 QI 696
++
Sbjct: 350 RM 351
>sp|Q91X85|FLVC2_MOUSE Feline leukemia virus subgroup C receptor-related protein 2
(Calcium-chelate transporter) (CCT)
Length = 551
Score = 101 bits (251), Expect = 3e-21
Identities = 66/242 (27%), Positives = 115/242 (47%), Gaps = 12/242 (4%)
Frame = +1
Query: 7 NGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCILC 186
N WI Y S+++ + Y V I++LS+ + + I L LPV W ++ FGLR I
Sbjct: 121 NAFQWIQYGSINNIFMNFYGVSAFAIDWLSMCYMLTYIPLLLPVAWMLEKFGLRTIAITG 180
Query: 187 GWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQRA 366
LN L A ++L + ++ + + M GQV+ S+AQ + P+++AS+WF +++ +
Sbjct: 181 SALNCLGAWVKLGSLEPHL-----FPVTMVGQVICSVAQVFILGMPSRIASVWFGADEVS 235
Query: 367 LATTIGAMGNPVGILLGSLLPPFLI------EYTMFNXXXXXXXXXXXXXXXPTLXXXXX 528
A ++ GN +GI +G L+PP L+ E ++ L
Sbjct: 236 TACSVAVFGNQLGIAIGFLVPPVLVPNIKDPEKLAYHISIMFYIIGGVATFLFILVIIVF 295
Query: 529 XXXXXXXXXXDRPLD------GVTFPEQLRRCLRNLSFLILSITFGMGLGLFTALSTLFE 690
+ L ++ + R +NL+F++L IT+G+ G F ALSTL
Sbjct: 296 KEKPKHPPSRAQSLSYALATTDASYLSSIVRLFKNLNFVLLVITYGLNAGAFYALSTLLN 355
Query: 691 QI 696
++
Sbjct: 356 RM 357
>sp|Q9UPI3|FLVC2_HUMAN Feline leukemia virus subgroup C receptor-related protein 2
(Calcium-chelate transporter) (CCT)
Length = 526
Score = 99.0 bits (245), Expect = 2e-20
Identities = 67/242 (27%), Positives = 117/242 (48%), Gaps = 12/242 (4%)
Frame = +1
Query: 7 NGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCILC 186
N WI Y S+++ + Y V I++LS+ + + I L LPV W ++ FGLR +
Sbjct: 98 NSFQWIQYGSINNIFMHFYGVSAFAIDWLSMCYMLTYIPLLLPVAWLLEKFGLRTIALTG 157
Query: 187 GWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQRA 366
LN L A ++L GS + + + + GQ++ S+AQ + P+++AS+WF +N+ +
Sbjct: 158 SALNCLGAWVKL-GS----LKPHLFPVTVVGQLICSVAQVFILGMPSRIASVWFGANEVS 212
Query: 367 LATTIGAMGNPVGILLGSLLPPFLI------EYTMFNXXXXXXXXXXXXXXXPTLXXXXX 528
A ++ GN +GI +G L+PP L+ + ++ L
Sbjct: 213 TACSVAVFGNQLGIAIGFLVPPVLVPNIEDRDELAYHISIMFYIIGGVATLLLILVIIVF 272
Query: 529 XXXXXXXXXXDRPLD-GVTFPE-----QLRRCLRNLSFLILSITFGMGLGLFTALSTLFE 690
+ L +T P+ + R +NL+F++L IT+G+ G F ALSTL
Sbjct: 273 KEKPKYPPSRAQSLSYALTSPDASYLGSIARLFKNLNFVLLVITYGLNAGAFYALSTLLN 332
Query: 691 QI 696
++
Sbjct: 333 RM 334
>sp|Q9Y5Y0|FLVC1_HUMAN Feline leukemia virus subgroup C receptor-related protein 1 (Feline
leukemia virus subgroup C receptor) (hFLVCR)
Length = 555
Score = 94.4 bits (233), Expect = 4e-19
Identities = 63/247 (25%), Positives = 109/247 (44%), Gaps = 13/247 (5%)
Frame = +1
Query: 7 NGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCILC 186
N WI Y+ +S+ Y V + I++LS+V+ + + L P W +D GLR T +L
Sbjct: 121 NAFQWIQYSIISNVFEGFYGVTLLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLG 180
Query: 187 GWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQRA 366
LN L A ++ ++ + + M GQ + S+AQ + P+++AS+WF + +
Sbjct: 181 SGLNCLGAWIKCGSVQ-----QHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVS 235
Query: 367 LATTIGAMGNPVGILLGSLLPPFLIE-------------YTMFNXXXXXXXXXXXXXXXP 507
A +GN +G +G LLPP L+ TMF
Sbjct: 236 TACATAVLGNQLGTAVGFLLPPVLVPNTQNDTNLLACNISTMFYGTSAVATLLFILTAIA 295
Query: 508 TLXXXXXXXXXXXXXXXDRPLDGVTFPEQLRRCLRNLSFLILSITFGMGLGLFTALSTLF 687
D P + ++ + +R +N+ F++L IT+G+ G F ++STL
Sbjct: 296 FKEKPRYPPSQAQAALQDSPPEEYSYKKSIRNLFKNIPFVLLLITYGIMTGAFYSVSTLL 355
Query: 688 EQIFCPF 708
Q+ +
Sbjct: 356 NQMILTY 362
>sp|Q9N1F2|FLVC1_FELCA Feline leukemia virus subgroup C receptor-related protein 1
Length = 560
Score = 91.3 bits (225), Expect = 3e-18
Identities = 63/247 (25%), Positives = 107/247 (43%), Gaps = 13/247 (5%)
Frame = +1
Query: 7 NGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCILC 186
N WI Y+ +S+ Y V I++LS+V+ + + L P W +D GLR T +L
Sbjct: 121 NAFQWIQYSVISNVFEGFYGVSSLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLG 180
Query: 187 GWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQRA 366
LN L A ++ ++ + + M GQ + S+AQ + P+++AS+WF + +
Sbjct: 181 SGLNCLGAWVKCASVQ-----QHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVS 235
Query: 367 LATTIGAMGNPVGILLGSLLPPFLIE-------------YTMFNXXXXXXXXXXXXXXXP 507
A +GN +G +G LLPP L+ TMF
Sbjct: 236 TACATAVLGNQLGAAIGFLLPPVLVPNTQNNTDLLACNISTMFYGTSSVATFLCFLTIIA 295
Query: 508 TLXXXXXXXXXXXXXXXDRPLDGVTFPEQLRRCLRNLSFLILSITFGMGLGLFTALSTLF 687
+ P ++ + +R RN+ F++L IT+G+ G F ++STL
Sbjct: 296 FKEKPQYPPSQAQAALQNSPPAKYSYKKSIRNLFRNVPFVLLLITYGIITGAFYSVSTLL 355
Query: 688 EQIFCPF 708
Q+ +
Sbjct: 356 NQMILTY 362
>sp|Q9ES43|FLVC1_MUSDU Feline leukemia virus subgroup C receptor-related protein 1
Length = 560
Score = 90.9 bits (224), Expect = 4e-18
Identities = 67/259 (25%), Positives = 109/259 (42%), Gaps = 25/259 (9%)
Frame = +1
Query: 7 NGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCILC 186
N WI Y+S+S+ Y+V IN+LS+V+ V + L P W +D GLR T +L
Sbjct: 114 NAFQWIQYSSISNVFEDFYEVSPLHINWLSMVYMVAYVPLIFPATWLLDTRGLRLTALLG 173
Query: 187 GWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQRA 366
LN L A ++ GS + + + M GQ++ S+AQ + P+ +AS+WF + +
Sbjct: 174 SGLNCLGAWVK-CGS----VQRHLFWVTMLGQILCSVAQVFILGLPSPVASVWFGPKEVS 228
Query: 367 LATTIGAMGNPVGILLGSLLPPFLIE-------------------------YTMFNXXXX 471
A +GN +G +G LLPP L+ TMF
Sbjct: 229 TACATAVLGNQLGTAVGFLLPPVLVPALGTQNNTGLLAHTQNNTDLLAHNINTMFYGTAF 288
Query: 472 XXXXXXXXXXXPTLXXXXXXXXXXXXXXXDRPLDGVTFPEQLRRCLRNLSFLILSITFGM 651
D P + ++ + RN+ F++L +++G+
Sbjct: 289 ISTFLFFLTVIAFKEKPPLPPSQAQAILRDSPPEEYSYKSSIWNLCRNIPFVLLLVSYGI 348
Query: 652 GLGLFTALSTLFEQIFCPF 708
G F ++STL QI +
Sbjct: 349 MTGAFYSISTLLNQIILTY 367
>sp|O01735|YC91_CAEEL Hypothetical transporter C09D4.1
Length = 586
Score = 88.2 bits (217), Expect = 3e-17
Identities = 58/242 (23%), Positives = 111/242 (45%), Gaps = 11/242 (4%)
Frame = +1
Query: 4 TNGILWISYASVSDQILTLYDVQIDLINYLSLVFPVITIVLGLPVIWGIDHFGLRATCIL 183
+NG WI Y+ +++ I Y V +++ S+++ + I+ +P W +D +GLR + +L
Sbjct: 163 SNGAQWIQYSIIANIISDYYKVSFQAVDWTSMIYMLTYILFFIPAAWLLDKWGLRLSVLL 222
Query: 184 CGWLNLLSAVLRLVGSDFYVRTEYRYKIAMAGQVVGSIAQPLAMFSPAKLASLWFPSNQR 363
N + A ++L+ + + + GQ + +Q + P +LA++WF ++
Sbjct: 223 GALGNCVGAWIKLLSTH-----PDSFWVTFVGQTIVGASQMFTLGIPPRLAAVWFGPDEV 277
Query: 364 ALATTIGAMGNPVGILLGSLLPPFL-----IEYTMF--NXXXXXXXXXXXXXXXPTLXXX 522
+ A +G GN +GI +G +LPP + +E+ + N +
Sbjct: 278 SRACALGVFGNQLGIAVGFVLPPLIVSNGSVEHVTYDLNTLFLGSAVLNTSILALVICFF 337
Query: 523 XXXXXXXXXXXXDRPLDGVTFPEQ----LRRCLRNLSFLILSITFGMGLGLFTALSTLFE 690
L+ TF LR+ + + F+IL IT+G+ G+F A+STL
Sbjct: 338 TARPAVPPSLAQVNALEEKTFDNNFWGTLRKLMTSRDFVILFITYGINTGVFYAISTLLS 397
Query: 691 QI 696
Q+
Sbjct: 398 QM 399
>sp|P38298|YPC1_YEAST Alkaline ceramidase YPC1
Length = 316
Score = 36.2 bits (82), Expect = 0.13
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Frame = +3
Query: 549 HFCRPPTRWRHISRAIAEMPAQSLI-PHSLHHIRDGIGIVHRSVDLV*ADLLSIWISRHF 725
H+C + W H+ R+I +P L+ PH HI G+GI V L ++++ +S ++
Sbjct: 217 HYC---SFWVHVRRSILALPLGVLLEPHGWWHILTGMGIYFYIVSLEHLRVITLNVSCNY 273
Query: 726 CWHLRWS--SDRVWTG 767
+ RW + +W G
Sbjct: 274 QFIWRWKVFPELIWKG 289
>sp|P76470|YFAV_ECOLI Inner membrane transport protein yfaV
Length = 429
Score = 35.4 bits (80), Expect = 0.22
Identities = 37/119 (31%), Positives = 48/119 (40%), Gaps = 4/119 (3%)
Frame = +1
Query: 100 VFPVITIVLGLPVIWGIDHFGLRA----TCILCGWLNLLSAVLRLVGSDFYVRTEYRYKI 267
+F V+ LG+P + G R T +L G+L+ A VRT R
Sbjct: 59 IFFVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWADTEAKFLIVRTLLR--A 116
Query: 268 AMAGQVVGSIAQPLAMFSPAKLASLWFPSNQRALATTIGAMGNPVGILLGSLLPPFLIE 444
A AG G I L S WFP RA + MG P+ + LGS L L+E
Sbjct: 117 AEAGFFPGMIY----------LTSQWFPQRNRASIMGLFYMGAPLALTLGSPLSGALLE 165
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,107,592
Number of Sequences: 369166
Number of extensions: 2199784
Number of successful extensions: 7356
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6873
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7341
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)