Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_K08
(494 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8N122|RPTOR_HUMAN Regulatory associated protein of mTOR... 96 4e-20
sp|Q8K4Q0|RPTOR_MOUSE Regulatory associated protein of mTOR... 95 8e-20
sp|P87141|MIP1_SCHPO WD-repeat protein mip1 82 9e-16
sp|P38873|YHY6_YEAST Hypothetical 175.8 kDa Trp-Asp repeats... 81 2e-15
sp|Q00808|HETE1_PODAN Vegetatible incompatibility protein H... 48 1e-05
sp|O02482|UNC37_CAEEL Transcription factor unc-37 (Uncoordi... 48 1e-05
sp|Q9C1X1|PWP2_SCHPO Periodic tryptophan protein 2 homolog 47 2e-05
sp|Q10051|PRP19_CAEEL PRP19/PSO4 homolog 43 4e-04
sp|Q6PE01|WDR57_MOUSE WD-repeat protein 57 41 0.001
sp|Q96DI7|WDR57_HUMAN WD-repeat protein 57 (Prp8-binding pr... 41 0.002
>sp|Q8N122|RPTOR_HUMAN Regulatory associated protein of mTOR (Raptor) (P150 target of
rapamycin (TOR)-scaffold protein)
Length = 1335
Score = 96.3 bits (238), Expect = 4e-20
Identities = 46/139 (33%), Positives = 81/139 (58%), Gaps = 1/139 (0%)
Frame = +1
Query: 1 QDPDIVTAWIALPDQICSNRPSGLITHWSQVMGQLTISGDVKYIRLWDSVQEGKISDMNT 180
++P++VTAW L D + + R +G++ W Q G L SGDV+ +R+WD+ +E K+ D+ T
Sbjct: 1104 KNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDREMKVQDIPT 1163
Query: 181 NSESCVSTIDRSQDGRLIVAGFGDGHIKMFDIRAPPNECVVNAGIGDVGWIHKIAYSDLT 360
++SCV+++ LIVAG GDG I+++D R +EC V W+ K +
Sbjct: 1164 GADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWVVKASLQKRP 1223
Query: 361 N-QVYSIGIDGELTTWSLR 414
+ + S+ ++G++ + R
Sbjct: 1224 DGHIVSVSVNGDVRIFDPR 1242
>sp|Q8K4Q0|RPTOR_MOUSE Regulatory associated protein of mTOR (Raptor) (P150 target of
rapamycin (TOR)-scaffold protein)
Length = 1335
Score = 95.1 bits (235), Expect = 8e-20
Identities = 47/134 (35%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Frame = +1
Query: 1 QDPDIVTAWIALPDQICSNRPSGLITHWSQVMGQLTISGDVKYIRLWDSVQEGKISDMNT 180
++P++VTAW L D + + R +G++ W Q G L SGDV+ +R+WD+ +E K+ D+ T
Sbjct: 1104 KNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMSSGDVRIVRIWDTDRETKVQDIPT 1163
Query: 181 NSESCVSTIDRSQDGRLIVAGFGDGHIKMFDIRAPPNECVVNAGIGDVGWIHKIAY--SD 354
++SCV+++ LIVAG GDG I+++D R +EC V W+ K AY
Sbjct: 1164 GADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHTAWVVK-AYLQKH 1222
Query: 355 LTNQVYSIGIDGEL 396
+ S+ ++G++
Sbjct: 1223 PEGHIVSVSVNGDV 1236
>sp|P87141|MIP1_SCHPO WD-repeat protein mip1
Length = 1313
Score = 81.6 bits (200), Expect = 9e-16
Identities = 45/155 (29%), Positives = 83/155 (53%), Gaps = 2/155 (1%)
Frame = +1
Query: 10 DIVTAWIALPDQICSNRPSGLITHWSQVMGQLTISGDVKYIRLWDSVQEGKISDMNTNSE 189
++VT+W +L D + +R + L+ W Q G L ++GDV+ IR+WD+ +E +++ S
Sbjct: 1073 ELVTSWNSLSDLVFGDRNASLLMSWQQNCGHLLVAGDVRVIRIWDASKEICYANLPVRSS 1132
Query: 190 SCVSTIDRSQDG-RLIVAGFGDGHIKMFDIRAPPNECVVNAGIGDVGWIHKI-AYSDLTN 363
+ ++++ G +IVAGF DG ++++D R P + + + I + S
Sbjct: 1133 NSITSLTSDLVGCNIIVAGFSDGVLRVYDKRLPARDSLTDVWKEHSSEIVNVEMQSSGMR 1192
Query: 364 QVYSIGIDGELTTWSLRHRHAPKTFITPSRRPVSL 468
++ S DGE+ W +R H+ +TF T + SL
Sbjct: 1193 ELISASSDGEVKLWDIRMNHSLQTFSTDNSGLTSL 1227
>sp|P38873|YHY6_YEAST Hypothetical 175.8 kDa Trp-Asp repeats containing protein in
GND1-IKI1 intergenic region
Length = 1541
Score = 80.9 bits (198), Expect = 2e-15
Identities = 51/160 (31%), Positives = 83/160 (51%), Gaps = 13/160 (8%)
Frame = +1
Query: 1 QDPD---IVTAWIALPDQICSNRPSGLITHWSQVMGQLTISGDVKYIRLWDSVQEGKISD 171
QD D IV+AW L D + + R +GL+T W Q+ G L +GDVK IR+WD+ E D
Sbjct: 1271 QDVDTFKIVSAWRGLTDMLLTPRSTGLLTEWLQIRGSLLTTGDVKVIRVWDAHTETVEVD 1330
Query: 172 MNTNSESCVSTIDRSQ-DGRLIVAGFGDGHIKMFDIRAPPNECVV---NAGIGDVG-WIH 336
+ + S ++++ Q G + VAGF DG ++++D R P + ++ AG G WI+
Sbjct: 1331 IPAKTSSLITSLTADQLAGNIFVAGFADGSLRVYDRRLDPRDSMIRRWRAGNDKQGVWIN 1390
Query: 337 KI-----AYSDLTNQVYSIGIDGELTTWSLRHRHAPKTFI 441
+ Y +L S +G + W +R ++F+
Sbjct: 1391 NVHLQRGGYRELV----SGATNGVVELWDIRSEDPVESFV 1426
>sp|Q00808|HETE1_PODAN Vegetatible incompatibility protein HET-E-1
Length = 1356
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/104 (32%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Frame = +1
Query: 97 GQLTISG-DVKYIRLWDSVQEGKISDMNTNSESCVSTIDRSQDGRLIVAGFGDGHIKMFD 273
GQ SG D I++WD+V + + +S V ++ S DG+ + +G DG IK++D
Sbjct: 1063 GQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDS-VWSVAFSPDGQRVASGSIDGTIKIWD 1121
Query: 274 IRAPPNECVVNAGIGDVGWIHKIAYSDLTNQVYSIGIDGELTTW 405
A C G GW+H +A+S +V S IDG + W
Sbjct: 1122 --AASGTCTQTLE-GHGGWVHSVAFSPDGQRVASGSIDGTIKIW 1162
Score = 29.3 bits (64), Expect = 5.3
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Frame = +1
Query: 97 GQLTISGDV-KYIRLWDSVQEGKISDMNTNSESCVSTIDRSQDGRLIVAGFGDGHIKMFD 273
GQ SG K I++WD+ G + V ++ S DG+ + +G D IK++D
Sbjct: 1189 GQRVASGSSDKTIKIWDTAS-GTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWD 1247
Query: 274 IRAPPNECVVNAG 312
+ +N G
Sbjct: 1248 TASGTCTQTLNVG 1260
>sp|O02482|UNC37_CAEEL Transcription factor unc-37 (Uncoordinated protein 37)
Length = 612
Score = 48.1 bits (113), Expect = 1e-05
Identities = 31/106 (29%), Positives = 51/106 (48%)
Frame = +1
Query: 103 LTISGDVKYIRLWDSVQEGKISDMNTNSESCVSTIDRSQDGRLIVAGFGDGHIKMFDIRA 282
L I G+ + LWD E K D+ T+S++C + + S D +L+ A DG+I ++DI
Sbjct: 389 LLIGGEASTVALWDLTTETKTLDLETDSQACYA-LAMSPDEKLLFACLADGNILIYDIH- 446
Query: 283 PPNECVVNAGIGDVGWIHKIAYSDLTNQVYSIGIDGELTTWSLRHR 420
N+ V G + S +++S G+D + W L R
Sbjct: 447 --NKVKVGTLPGHQDGASCLDLSKDGTKLWSGGLDNSVRCWDLAQR 490
>sp|Q9C1X1|PWP2_SCHPO Periodic tryptophan protein 2 homolog
Length = 854
Score = 47.4 bits (111), Expect = 2e-05
Identities = 35/138 (25%), Positives = 61/138 (44%)
Frame = +1
Query: 40 DQICSNRPSGLITHWSQVMGQLTISGDVKYIRLWDSVQEGKISDMNTNSESCVSTIDRSQ 219
D + N I S +GQL + W+ E + ++ ++ +ST+ S
Sbjct: 300 DTLTVNSTGDWIAIGSSKLGQLLV---------WEWQSESYVLKQQSHYDA-LSTLQYSS 349
Query: 220 DGRLIVAGFGDGHIKMFDIRAPPNECVVNAGIGDVGWIHKIAYSDLTNQVYSIGIDGELT 399
DG+ I+ G DG IK++D+ + C+V + + +S N ++S +DG +
Sbjct: 350 DGQRIITGADDGKIKVWDMNS--GFCIVTF-TQHTSAVSGLCFSKRGNVLFSSSLDGSVR 406
Query: 400 TWSLRHRHAPKTFITPSR 453
W L +TF PSR
Sbjct: 407 AWDLIRYRNFRTFTAPSR 424
>sp|Q10051|PRP19_CAEEL PRP19/PSO4 homolog
Length = 492
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/94 (27%), Positives = 46/94 (48%)
Frame = +1
Query: 184 SESCVSTIDRSQDGRLIVAGFGDGHIKMFDIRAPPNECVVNAGIGDVGWIHKIAYSDLTN 363
S+ V +I+ DG + G D +K++D++ N+ V A G + IA+S+
Sbjct: 337 SQIAVHSIEFHPDGLIFGTGAADAVVKIWDLK---NQTVAAAFPGHTAAVRSIAFSENGY 393
Query: 364 QVYSIGIDGELTTWSLRHRHAPKTFITPSRRPVS 465
+ + DGE+ W LR KTF ++P++
Sbjct: 394 YLATGSEDGEVKLWDLRKLKNLKTFANEEKQPIN 427
>sp|Q6PE01|WDR57_MOUSE WD-repeat protein 57
Length = 358
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/112 (22%), Positives = 52/112 (46%)
Frame = +1
Query: 79 HWSQVMGQLTISGDVKYIRLWDSVQEGKISDMNTNSESCVSTIDRSQDGRLIVAGFGDGH 258
H++ L + K + +WDS ++ + ++ S + +L+ G DG
Sbjct: 117 HYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGT 176
Query: 259 IKMFDIRAPPNECVVNAGIGDVGWIHKIAYSDLTNQVYSIGIDGELTTWSLR 414
+K++DIR + V + + + ++D ++Q+ S GID ++ W LR
Sbjct: 177 VKLWDIR---KKAAVQT-FQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR 224
>sp|Q96DI7|WDR57_HUMAN WD-repeat protein 57 (Prp8-binding protein) (hPRP8BP) (U5
snRNP-specific 40 kDa protein) (38 kDa splicing factor)
Length = 357
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/112 (21%), Positives = 52/112 (46%)
Frame = +1
Query: 79 HWSQVMGQLTISGDVKYIRLWDSVQEGKISDMNTNSESCVSTIDRSQDGRLIVAGFGDGH 258
H++ L + K + +WDS ++ + ++ S + +L+ G DG
Sbjct: 116 HYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGT 175
Query: 259 IKMFDIRAPPNECVVNAGIGDVGWIHKIAYSDLTNQVYSIGIDGELTTWSLR 414
+K++DIR + + + + + ++D ++Q+ S GID ++ W LR
Sbjct: 176 VKLWDIR---KKAAIQT-FQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR 223
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,950,886
Number of Sequences: 369166
Number of extensions: 1379464
Number of successful extensions: 3467
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3255
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3448
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3069744620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)