Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_K05
(931 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8IVD9|NUDC3_HUMAN NudC domain containing protein 3 115 2e-25
sp|Q8R1N4|NUDC3_MOUSE NudC domain containing protein 3 111 3e-24
sp|Q63525|NUDC_RAT Nuclear migration protein nudC (Nuclear ... 87 5e-17
sp|O35685|NUDC_MOUSE Nuclear migration protein nudC (Nuclea... 87 9e-17
sp|Q9Y266|NUDC_HUMAN Nuclear migration protein nudC (Nuclea... 82 2e-15
sp|Q5ZIN1|NUDC_CHICK Nuclear migration protein nudC (Nuclea... 82 2e-15
sp|P17624|NUDC_EMENI Nuclear movement protein nudC 69 2e-11
sp|P13395|SPTCA_DROME Spectrin alpha chain 34 0.51
sp|P40010|NUG1_YEAST Nuclear GTP-binding protein NUG1 (Nucl... 33 1.1
sp|O51446|RL6_BORBU 50S ribosomal protein L6 32 3.3
>sp|Q8IVD9|NUDC3_HUMAN NudC domain containing protein 3
Length = 361
Score = 115 bits (287), Expect = 2e-25
Identities = 61/176 (34%), Positives = 98/176 (55%)
Frame = +1
Query: 367 ESYNGSVGDCYTWSQMIGELDIRIKVPIIXXXXXXXXXXXXXXHINVSYTFQNEVIPVID 546
+SYNG+V + YTWSQ +L++R+ VP I V+ +N +++
Sbjct: 180 DSYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGECVLME 239
Query: 547 KELSWDIKKNEVFWSFDPKENKILISVEKVQERWWEALFVGDVTINTRKIDCSRPMSDLD 726
+L+ I WS +P + +L+++ KV E WW A+ G+ I+ KI+ R M+ +D
Sbjct: 240 GKLTHKINTESSLWSLEPGKC-VLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVD 298
Query: 727 DEAQAKIHKLMHDNRQKQLGLPTSDQQKINDALKKAWDLEGSPFKGKDFDLSNIDI 894
+E QA + +L D QK G P S + K+++ LKK WD EGSPF+G+ FD + +I
Sbjct: 299 EEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNI 354
Score = 64.7 bits (156), Expect = 4e-10
Identities = 28/57 (49%), Positives = 39/57 (68%)
Frame = +3
Query: 33 EKYDNILLDVIQQVNNLPNFLDIIFGFLRRRTDLYYLMNNNQQNMGFPPGKAEKLIL 203
E YD LL ++Q V N+ +FL ++FGFL R+TD Y L+ + MGFPPG A+ L+L
Sbjct: 7 ELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVL 63
>sp|Q8R1N4|NUDC3_MOUSE NudC domain containing protein 3
Length = 363
Score = 111 bits (277), Expect = 3e-24
Identities = 59/176 (33%), Positives = 96/176 (54%)
Frame = +1
Query: 367 ESYNGSVGDCYTWSQMIGELDIRIKVPIIXXXXXXXXXXXXXXHINVSYTFQNEVIPVID 546
+SYNG++ + Y WSQ +L++R+ VP I V+ +N +++
Sbjct: 182 DSYNGAIRENYIWSQDYTDLEVRVPVPKHVMKGKQVSVALSSGTIRVAMVEENGERVLME 241
Query: 547 KELSWDIKKNEVFWSFDPKENKILISVEKVQERWWEALFVGDVTINTRKIDCSRPMSDLD 726
+L+ I WS +P +L+++ KV E WW A+ G+ I+ KI+ R M+ +D
Sbjct: 242 GKLTHKINTESSLWSLEPGRC-VLVNLSKVGEYWWSAILEGEEPIDIDKINKERSMATVD 300
Query: 727 DEAQAKIHKLMHDNRQKQLGLPTSDQQKINDALKKAWDLEGSPFKGKDFDLSNIDI 894
+E QA + +L D QK G P S + K+++ LKK WD EGSPF+G+ FD + +I
Sbjct: 301 EEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNI 356
Score = 64.7 bits (156), Expect = 4e-10
Identities = 28/57 (49%), Positives = 39/57 (68%)
Frame = +3
Query: 33 EKYDNILLDVIQQVNNLPNFLDIIFGFLRRRTDLYYLMNNNQQNMGFPPGKAEKLIL 203
E YD LL ++Q V N+ +FL ++FGFL R+TD Y L+ + MGFPPG A+ L+L
Sbjct: 7 ELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVL 63
>sp|Q63525|NUDC_RAT Nuclear migration protein nudC (Nuclear distribution protein C
homolog) (c15)
Length = 332
Score = 87.4 bits (215), Expect = 5e-17
Identities = 54/158 (34%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = +1
Query: 376 NGSVGDCYTWSQMIGELDIRIKVPI-IXXXXXXXXXXXXXXHINVSYTFQNEVIPVIDKE 552
NG+ Y W+Q + ELD+ + + H+ V Q PVID E
Sbjct: 166 NGADLPNYRWTQTLSELDLAVPFRVSFRLKGKDVVVDIQRRHLRVGLKGQ---APVIDGE 222
Query: 553 LSWDIKKNEVFWSFDPKENKILISVEKVQE-RWWEALFVGDVTINTRKIDCSRP-MSDLD 726
L ++K E W + + + + +EK+ + WW L D INT+KI+ +SDLD
Sbjct: 223 LYNEVKVEESSWLIEDGK-VVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLD 281
Query: 727 DEAQAKIHKLMHDNRQKQLGLPTSDQQKINDALKKAWD 840
E ++ + K+M+D RQK +GLPTSD+QK + LKK D
Sbjct: 282 SETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 319
Score = 32.0 bits (71), Expect = 2.5
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +3
Query: 33 EKYDNILLDVIQQ-VNNLPNFLDIIFGFLRRRTDLYYLMNNNQQNMGFPPGKAEKLI 200
E++D +LL + QQ + ++ F FLRR+TD + +G G AEKLI
Sbjct: 8 ERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLI 55
>sp|O35685|NUDC_MOUSE Nuclear migration protein nudC (Nuclear distribution protein C
homolog) (Silica-induced gene 92 protein) (SIG-92)
Length = 332
Score = 86.7 bits (213), Expect = 9e-17
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Frame = +1
Query: 376 NGSVGDCYTWSQMIGELDIRIKVPI-IXXXXXXXXXXXXXXHINVSYTFQNEVIPVIDKE 552
NG+ Y W+Q + ELD+ + + H+ V Q PV+D E
Sbjct: 166 NGADLPNYRWTQTLAELDLAVPFRVSFRLKGKDVVVDIQRRHLRVGLKGQP---PVVDGE 222
Query: 553 LSWDIKKNEVFWSFDPKENKILISVEKVQE-RWWEALFVGDVTINTRKIDCSRP-MSDLD 726
L ++K E W + + + + +EK+ + WW L D INT+KI+ +SDLD
Sbjct: 223 LYNEVKVEESSWLIEDGK-VVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLD 281
Query: 727 DEAQAKIHKLMHDNRQKQLGLPTSDQQKINDALKKAWD 840
E ++ + K+M+D RQK +GLPTSD+QK + LKK D
Sbjct: 282 SETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 319
Score = 32.0 bits (71), Expect = 2.5
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +3
Query: 33 EKYDNILLDVIQQ-VNNLPNFLDIIFGFLRRRTDLYYLMNNNQQNMGFPPGKAEKLI 200
E++D +LL + QQ + ++ F FLRR+TD + +G G AEKLI
Sbjct: 8 ERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLI 55
>sp|Q9Y266|NUDC_HUMAN Nuclear migration protein nudC (Nuclear distribution protein C
homolog)
Length = 331
Score = 82.4 bits (202), Expect = 2e-15
Identities = 52/158 (32%), Positives = 80/158 (50%), Gaps = 3/158 (1%)
Frame = +1
Query: 376 NGSVGDCYTWSQMIGELDIRIKVPI-IXXXXXXXXXXXXXXHINVSYTFQNEVIPVIDKE 552
NG+ Y W+Q + ELD+ + + H+ V Q +I D E
Sbjct: 165 NGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAII---DGE 221
Query: 553 LSWDIKKNEVFWSFDPKENKILISVEKVQE-RWWEALFVGDVTINTRKIDCSRP-MSDLD 726
L ++K E W + + + + +EK+ + WW L D INT+KI+ +SDLD
Sbjct: 222 LYNEVKVEESSWLIEDGK-VVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLD 280
Query: 727 DEAQAKIHKLMHDNRQKQLGLPTSDQQKINDALKKAWD 840
E ++ + K+M+D RQK +GLPTSD+QK + LKK D
Sbjct: 281 SETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 318
Score = 32.0 bits (71), Expect = 2.5
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = +3
Query: 33 EKYDNILLDVIQQ-VNNLPNFLDIIFGFLRRRTDLYYLMNNNQQNMGFPPGKAEKLI 200
E++D +LL + QQ + ++ F FLRR+TD + +G G AEKLI
Sbjct: 8 ERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLI 55
>sp|Q5ZIN1|NUDC_CHICK Nuclear migration protein nudC (Nuclear distribution protein C
homolog)
Length = 341
Score = 82.4 bits (202), Expect = 2e-15
Identities = 53/155 (34%), Positives = 78/155 (50%), Gaps = 3/155 (1%)
Frame = +1
Query: 376 NGSVGDCYTWSQMIGELDIRIKVPI-IXXXXXXXXXXXXXXHINVSYTFQNEVIPVIDKE 552
NG+ Y W+Q + ELD+ I + + V PVID E
Sbjct: 175 NGADLPNYRWTQTLSELDLAIPFKVTFRLKGKDVVVDIQRRRLRVGLKGHP---PVIDGE 231
Query: 553 LSWDIKKNEVFWSFDPKENKILISVEKVQE-RWWEALFVGDVTINTRKIDCSRP-MSDLD 726
L ++K E W + + + + +EK+ + WW L D INT+KI+ +SDLD
Sbjct: 232 LFNEVKVEESSWLIEDGKT-VTVHLEKINKMEWWNKLVSTDPEINTKKINPENSKLSDLD 290
Query: 727 DEAQAKIHKLMHDNRQKQLGLPTSDQQKINDALKK 831
E ++ + K+M+D RQK +GLPTSD+QK D LKK
Sbjct: 291 SETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKK 325
Score = 32.0 bits (71), Expect = 2.5
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +3
Query: 33 EKYDNILLDVIQQ-VNNLPNFLDIIFGFLRRRTDLYYLMNNNQQNMGFPPGKAEKLILD 206
+++D ILL + QQ + ++ F FLRR+TD + G G AEKLI D
Sbjct: 13 DRFDGILLAMAQQHQGGVCELVNTFFSFLRRKTDFF---------TGGEDGVAEKLITD 62
>sp|P17624|NUDC_EMENI Nuclear movement protein nudC
Length = 198
Score = 68.9 bits (167), Expect = 2e-11
Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 6/151 (3%)
Frame = +1
Query: 397 YTWSQMIGELDIRIKVPIIXXXXXXXXXXXXXXHINVSYTFQNEVIPVIDKELSWDIKKN 576
Y W+Q I ++D+ I V I V +N + ID + IK +
Sbjct: 34 YKWTQTIRDVDVTIPVSA-NLKGRDLDVVLKKDSIKVKVKGENGEV-FIDGQFPHPIKPS 91
Query: 577 EVFWSFD----PKENKILISVEKV-QERWWEALFVGDVTINTRKIDCSRP-MSDLDDEAQ 738
E W+ + P ++ I ++KV Q WW + I+ KI +SDLD E +
Sbjct: 92 ESSWTLETTSKPPGKEVSIHLDKVNQMEWWAHVVTTAPKIDVSKITPENSSLSDLDGETR 151
Query: 739 AKIHKLMHDNRQKQLGLPTSDQQKINDALKK 831
A + K+M+D RQK++G PTSD+Q+ D LKK
Sbjct: 152 AMVEKMMYDQRQKEMGAPTSDEQRKMDILKK 182
>sp|P13395|SPTCA_DROME Spectrin alpha chain
Length = 2415
Score = 34.3 bits (77), Expect = 0.51
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Frame = +1
Query: 589 SFDPKENKILISVEKVQERWWEALF-VGDVTINTR----KIDCSRPMSDLD---DEAQAK 744
+F PKE KIL +VE +QER + L D I TR K++ SR DE ++
Sbjct: 3 NFTPKEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESW 62
Query: 745 IHKLMHDNRQKQLGLPTSDQQKINDALKKAWDLEGSPFKGKDFDLSN 885
IH+ + ++ PT+ Q KI +A++ E S L N
Sbjct: 63 IHEKLQAASEESYRDPTNLQAKIQK--HQAFEAEVSAHSNAIVSLDN 107
>sp|P40010|NUG1_YEAST Nuclear GTP-binding protein NUG1 (Nuclear GTPase 1)
Length = 520
Score = 33.1 bits (74), Expect = 1.1
Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Frame = +1
Query: 703 SRPMSDLDDEAQAKIHKLMHDNRQKQLGLPTSDQQKIND-----------ALKKAWDLEG 849
++ M DL++ AK +L K+ G+ D+ I D A + A + EG
Sbjct: 66 AKKMKDLEERELAKQQRLEARKAAKEQGVDAMDEDMIEDDENGLAALVESAQQAAAEYEG 125
Query: 850 SPFKGKDFDLSNIDIVAYSDDF 915
+P D +D++ Y+ DF
Sbjct: 126 TPSNDADVRDDELDVIDYNIDF 147
>sp|O51446|RL6_BORBU 50S ribosomal protein L6
Length = 180
Score = 31.6 bits (70), Expect = 3.3
Identities = 12/32 (37%), Positives = 22/32 (68%)
Frame = +1
Query: 247 LEESVNTKPKQTEIIKDKVLNDNKSKAQESVH 342
+++S+N K + +I D+VLND K+KA ++
Sbjct: 37 IKDSINVKVENGSVIVDRVLNDKKAKAYHGLY 68
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,749,176
Number of Sequences: 369166
Number of extensions: 1862533
Number of successful extensions: 5027
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4805
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5017
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9558791870
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)