Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_J19
(645 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P20232|TFS2_DROME Transcription elongation factor S-II (... 186 4e-47
sp|P52652|TFS2_CAEEL Putative transcription elongation fact... 174 2e-43
sp|Q15560|TCEA2_HUMAN Transcription elongation factor A pro... 172 7e-43
sp|Q4KLL0|TCEA1_RAT Transcription elongation factor A prote... 170 3e-42
sp|P10711|TCEA1_MOUSE Transcription elongation factor A pro... 170 3e-42
sp|P23193|TCEA1_HUMAN Transcription elongation factor A pro... 170 3e-42
sp|Q9QVN7|TCEA2_MOUSE Transcription elongation factor A pro... 166 4e-41
sp|Q63799|TCEA2_RAT Transcription elongation factor A prote... 166 5e-41
sp|P23881|TCEA3_MOUSE Transcription elongation factor A pro... 157 3e-38
sp|O75764|TCEA3_HUMAN Transcription elongation factor A pro... 153 3e-37
>sp|P20232|TFS2_DROME Transcription elongation factor S-II (RNA polymerase II elongation
factor DMS-II) (TFIIS)
Length = 313
Score = 186 bits (472), Expect = 4e-47
Identities = 86/164 (52%), Positives = 121/164 (73%)
Frame = +3
Query: 6 TDPFRIKARVMISQALESGHVPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTRVMN 185
TD RIK R M++ AL+ G VPEG + E ++ ++E AI++ F N+ YK R+R+RV N
Sbjct: 150 TDAVRIKCREMLATALKIGEVPEGCGEPEEMAAELEDAIYSEFNNTDMKYKNRIRSRVAN 209
Query: 186 LRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGGGTE 365
L+D N LR N + G V+A++LA M+ E+MAS EMK++R+K++ E I+++QL GT+
Sbjct: 210 LKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTK 269
Query: 366 TDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
TDL+KC KC++ C+YNQ+QTRSADEPMTTF CN CG+RWKFC
Sbjct: 270 TDLLKCAKCKKRNCTYNQLQTRSADEPMTTFVMCNECGNRWKFC 313
>sp|P52652|TFS2_CAEEL Putative transcription elongation factor S-II (TFIIS)
Length = 308
Score = 174 bits (440), Expect = 2e-43
Identities = 81/163 (49%), Positives = 113/163 (69%)
Frame = +3
Query: 9 DPFRIKARVMISQALESGHVPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTRVMNL 188
D R+K+ ++ AL G +P+G+ D E L+VQIE +++V ++ +Y VR+R+ NL
Sbjct: 146 DETRLKSAQLLLSALRFGDMPQGTLDPEELAVQIEEKLYSVHRDTNKSYSAAVRSRIFNL 205
Query: 189 RDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGGGTET 368
RD+ N+ LR NVL G V AEK A M+SE+MAS E++EMR K+ E I E Q+ + GT +
Sbjct: 206 RDKKNLALRENVLTGVVRAEKFATMTSEEMASAEIREMRDKFTKEAILEHQMSVQQGTPS 265
Query: 369 DLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
D+ KC KC + C+Y Q+QTRS+DEPMTTF FC CG+RWKFC
Sbjct: 266 DMFKCGKCGKKNCTYTQLQTRSSDEPMTTFVFCLECGNRWKFC 308
>sp|Q15560|TCEA2_HUMAN Transcription elongation factor A protein 2 (Transcription
elongation factor S-II protein 2) (Testis-specific S-II)
(Transcription elongation factor TFIIS.l)
Length = 299
Score = 172 bits (436), Expect = 7e-43
Identities = 87/167 (52%), Positives = 113/167 (67%), Gaps = 2/167 (1%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALESGH--VPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTR 176
T D R K R M++ AL++ H V G+ D E LS QIE IF N+ YK RVR+R
Sbjct: 134 TCDAVRNKCREMLTAALQTDHDHVAIGA-DCERLSAQIEECIFRDVGNTDMKYKNRVRSR 192
Query: 177 VMNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGG 356
+ NL+D N +LR NVL G ++ +++A+M+SE+MAS E+KE+RK E I E Q+ G
Sbjct: 193 ISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTG 252
Query: 357 GTETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
GT+TDL C KCR+ C+Y QVQTRS+DEPMTTF CN CG+RWKFC
Sbjct: 253 GTQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC 299
>sp|Q4KLL0|TCEA1_RAT Transcription elongation factor A protein 1 (Transcription
elongation factor S-II protein 1)
Length = 301
Score = 170 bits (431), Expect = 3e-42
Identities = 86/167 (51%), Positives = 110/167 (65%), Gaps = 2/167 (1%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALESG--HVPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTR 176
T+D R+K R M++ AL +G +V G+ D E L QIE AI+ N+ YK RVR+R
Sbjct: 136 TSDSVRLKCREMLAAALRTGDDYVAIGA-DEEELGSQIEEAIYQEIRNTDMKYKNRVRSR 194
Query: 177 VMNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGG 356
+ NL+D N LR NVL G + + A M++E+MAS E+KEMRK E I E Q+ G
Sbjct: 195 ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG 254
Query: 357 GTETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
GT+TDL C KC++ C+Y QVQTRSADEPMTTF CN CG+RWKFC
Sbjct: 255 GTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 301
>sp|P10711|TCEA1_MOUSE Transcription elongation factor A protein 1 (Transcription
elongation factor S-II protein 1) (Transcription
elongation factor TFIIS.o)
Length = 301
Score = 170 bits (431), Expect = 3e-42
Identities = 86/167 (51%), Positives = 110/167 (65%), Gaps = 2/167 (1%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALESG--HVPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTR 176
T+D R+K R M++ AL +G +V G+ D E L QIE AI+ N+ YK RVR+R
Sbjct: 136 TSDSVRLKCREMLAAALRTGDDYVAIGA-DEEELGSQIEEAIYQEIRNTDMKYKNRVRSR 194
Query: 177 VMNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGG 356
+ NL+D N LR NVL G + + A M++E+MAS E+KEMRK E I E Q+ G
Sbjct: 195 ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG 254
Query: 357 GTETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
GT+TDL C KC++ C+Y QVQTRSADEPMTTF CN CG+RWKFC
Sbjct: 255 GTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 301
>sp|P23193|TCEA1_HUMAN Transcription elongation factor A protein 1 (Transcription
elongation factor S-II protein 1) (Transcription
elongation factor TFIIS.o)
Length = 301
Score = 170 bits (430), Expect = 3e-42
Identities = 85/167 (50%), Positives = 110/167 (65%), Gaps = 2/167 (1%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALESG--HVPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTR 176
T+D R+K R M++ AL +G ++ G+ D E L QIE AI+ N+ YK RVR+R
Sbjct: 136 TSDSVRLKCREMLAAALRTGDDYIAIGA-DEEELGSQIEEAIYQEIRNTDMKYKNRVRSR 194
Query: 177 VMNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGG 356
+ NL+D N LR NVL G + + A M++E+MAS E+KEMRK E I E Q+ G
Sbjct: 195 ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTG 254
Query: 357 GTETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
GT+TDL C KC++ C+Y QVQTRSADEPMTTF CN CG+RWKFC
Sbjct: 255 GTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 301
>sp|Q9QVN7|TCEA2_MOUSE Transcription elongation factor A protein 2 (Transcription
elongation factor S-II protein 2) (Testis-specific S-II)
(Protein S-II-T1) (Transcription elongation factor
TFIIS.l)
Length = 299
Score = 166 bits (421), Expect = 4e-41
Identities = 85/167 (50%), Positives = 112/167 (67%), Gaps = 2/167 (1%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALESGH--VPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTR 176
T D R K R M++ AL++ H V G + E+LS QIE IF N+ YK RVR+R
Sbjct: 134 TCDAVRNKCREMLTLALQTDHDHVAVG-VNCEHLSSQIEECIFLDVGNTDMKYKNRVRSR 192
Query: 177 VMNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGG 356
+ NL+D N LR NVL G ++ +++A+M+SE+MAS E+KE+RK E I E Q+ G
Sbjct: 193 ISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTG 252
Query: 357 GTETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
GT+TDL C KCR+ C+Y QVQTRS+DEPMTT+ CN CG+RWKFC
Sbjct: 253 GTQTDLFTCNKCRKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKFC 299
>sp|Q63799|TCEA2_RAT Transcription elongation factor A protein 2 (Transcription
elongation factor S-II protein 2) (Testis-specific S-II)
(Protein S-II-T1) (Transcription elongation factor
TFIIS.l)
Length = 299
Score = 166 bits (420), Expect = 5e-41
Identities = 85/167 (50%), Positives = 111/167 (66%), Gaps = 2/167 (1%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALESGH--VPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTR 176
T D R K R M++ AL++ H V G E+LS QIE IF N+ YK RVR+R
Sbjct: 134 TCDAVRNKCREMLTLALQTDHDHVAVG-VSCEHLSSQIEECIFLDVGNTDMKYKNRVRSR 192
Query: 177 VMNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGG 356
+ NL+D N LR NVL G ++ +++A+M+SE+MAS E+KE+RK E I E Q+ G
Sbjct: 193 ISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTG 252
Query: 357 GTETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
GT+TDL C KCR+ C+Y QVQTRS+DEPMTT+ CN CG+RWKFC
Sbjct: 253 GTQTDLFTCNKCRKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKFC 299
>sp|P23881|TCEA3_MOUSE Transcription elongation factor A protein 3 (Transcription
elongation factor S-II protein 3) (Transcription
elongation factor TFIIS.h)
Length = 347
Score = 157 bits (396), Expect = 3e-38
Identities = 77/166 (46%), Positives = 109/166 (65%), Gaps = 1/166 (0%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALES-GHVPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTRV 179
T D R K M+S AL++ + + + + L+ +IE I+ ++ Y+ RVR+R+
Sbjct: 182 TGDSVRDKCVEMLSAALKAEDNFKDYGVNCDKLASEIEDHIYQELKSTDMKYRNRVRSRI 241
Query: 180 MNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGGG 359
NL+D N LR NVL+G +S E +A M++E+MAS E++E+R E I E Q+ GG
Sbjct: 242 SNLKDPRNPGLRRNVLSGAISPELIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGG 301
Query: 360 TETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
T TDL++C KC++ C+YNQVQTRSADEPMTTF CN CG+RWKFC
Sbjct: 302 TTTDLLRCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC 347
>sp|O75764|TCEA3_HUMAN Transcription elongation factor A protein 3 (Transcription
elongation factor S-II protein 3) (Transcription
elongation factor TFIIS.h)
Length = 348
Score = 153 bits (387), Expect = 3e-37
Identities = 76/166 (45%), Positives = 107/166 (64%), Gaps = 1/166 (0%)
Frame = +3
Query: 3 TTDPFRIKARVMISQALESGH-VPEGSYDTEYLSVQIESAIFNVFMNSGPTYKQRVRTRV 179
T D R K M+S AL++ + + + ++ +IE I+ ++ Y+ RVR+R+
Sbjct: 183 TGDSVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRI 242
Query: 180 MNLRDQNNVELRLNVLAGTVSAEKLALMSSEDMASKEMKEMRKKYMGEVIHESQLCIGGG 359
NL+D N LR NVL+G +SA +A M++E+MAS E++E+R E I E Q+ GG
Sbjct: 243 SNLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGG 302
Query: 360 TETDLIKCPKCRESRCSYNQVQTRSADEPMTTFAFCNSCGHRWKFC 497
T TDL +C KC++ C+YNQVQTRSADEPMTTF CN CG+RWKFC
Sbjct: 303 TTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC 348
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,956,639
Number of Sequences: 369166
Number of extensions: 1681002
Number of successful extensions: 5361
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5138
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5355
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5267491560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)