Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_F10
(571 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RAL... 233 2e-61
sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial... 228 1e-59
sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH... 226 2e-59
sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 (RalDH2) (RAL... 226 2e-59
sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RAL... 226 3e-59
sp|O93344|AL1A2_CHICK Retinal dehydrogenase 2 (RalDH2) (RAL... 225 5e-59
sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial... 225 7e-59
sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial... 224 9e-59
sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial p... 224 1e-58
sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 (RalDH1) (RAL... 224 1e-58
>sp|P27463|AL1A1_CHICK Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 509
Score = 233 bits (595), Expect = 2e-61
Identities = 110/160 (68%), Positives = 131/160 (81%)
Frame = +2
Query: 26 QGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAKEEI 205
QGPQ+DK+Q KI+DLI SGK EGA+L GG G+KGYF++PT+FS V D+MRIAKEEI
Sbjct: 350 QGPQIDKEQFQKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEI 409
Query: 206 FGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAFD 385
FGPV QIMKFK IDEVI+RANN YGLAA+VFTKDI+K++ +L+AGTVW+NCY AF
Sbjct: 410 FGPVQQIMKFKTIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFS 469
Query: 386 AAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A PFGG+K SG GRELGEYGL Y+EVK VTIK+P K+S
Sbjct: 470 AQCPFGGFKMSGNGRELGEYGLQEYTEVKTVTIKIPQKNS 509
>sp|P12762|ALDH2_HORSE Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDHI)
(ALDH-E2)
Length = 500
Score = 228 bits (580), Expect = 1e-59
Identities = 106/161 (65%), Positives = 131/161 (81%)
Frame = +2
Query: 23 DQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAKEE 202
+QGPQVD+ Q NK++ I SGK EGA+L GG D+GYF++PT+F V D M IAKEE
Sbjct: 340 EQGPQVDETQFNKVLGYIKSGKEEGAKLLCGGGAAADRGYFIQPTVFGDVQDGMTIAKEE 399
Query: 203 IFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAF 382
IFGPVMQI+KFK I+EV+ RANN++YGLAA+VFTKD++K+ ++ Q+L+AGTVWINCYD F
Sbjct: 400 IFGPVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVF 459
Query: 383 DAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +PFGGYK SG GRELGEYGL Y+EVK VTIKVP K+S
Sbjct: 460 GAQSPFGGYKMSGNGRELGEYGLQAYTEVKTVTIKVPQKNS 500
>sp|Q63639|AL1A2_RAT Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 226 bits (577), Expect = 2e-59
Identities = 103/163 (63%), Positives = 136/163 (83%)
Frame = +2
Query: 17 TRDQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAK 196
T +QGPQ+DK Q NKI++LI SG +EGA+L GGK LG KG+F+EPT+FS V D+MRIAK
Sbjct: 337 TTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAK 396
Query: 197 EEIFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYD 376
EEIFGPV +I++FK +DEVIERANN+++GL A+VFT DI K++ + +++AGTVWINCY+
Sbjct: 397 EEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYN 456
Query: 377 AFDAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +A +PFGG+K SG GRE+GE+GL YSEVK VT+K+P K+S
Sbjct: 457 ALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 226 bits (577), Expect = 2e-59
Identities = 103/163 (63%), Positives = 136/163 (83%)
Frame = +2
Query: 17 TRDQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAK 196
T +QGPQ+DK Q NKI++LI SG +EGA+L GGK LG KG+F+EPT+FS V D+MRIAK
Sbjct: 337 TTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAK 396
Query: 197 EEIFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYD 376
EEIFGPV +I++FK +DEVIERANN+++GL A+VFT DI K++ + +++AGTVWINCY+
Sbjct: 397 EEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYN 456
Query: 377 AFDAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +A +PFGG+K SG GRE+GE+GL YSEVK VT+K+P K+S
Sbjct: 457 ALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|Q62148|AL1A2_MOUSE Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 226 bits (576), Expect = 3e-59
Identities = 102/163 (62%), Positives = 136/163 (83%)
Frame = +2
Query: 17 TRDQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAK 196
T +QGPQ+DK Q NK+++LI SG +EGA+L GGK LG KG+F+EPT+FS V D+MRIAK
Sbjct: 337 TTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAK 396
Query: 197 EEIFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYD 376
EEIFGPV +I++FK +DEVIERANN+++GL A+VFT DI K++ + +++AGTVWINCY+
Sbjct: 397 EEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYN 456
Query: 377 AFDAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +A +PFGG+K SG GRE+GE+GL YSEVK VT+K+P K+S
Sbjct: 457 ALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS 499
>sp|O93344|AL1A2_CHICK Retinal dehydrogenase 2 (RalDH2) (RALDH 2) (RALDH(II))
(Retinaldehyde-specific dehydrogenase type 2) (Aldehyde
dehydrogenase family 1 member A2)
Length = 499
Score = 225 bits (574), Expect = 5e-59
Identities = 104/163 (63%), Positives = 135/163 (82%)
Frame = +2
Query: 17 TRDQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAK 196
T +QGPQ+DK Q NKI++LI SG +EGA+L GGK LG KG+F+EPT+FS V D+MRIAK
Sbjct: 337 TTEQGPQIDKKQYNKILELIQSGITEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAK 396
Query: 197 EEIFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYD 376
EEIFGPV +I++FK +DEVIERANN+++GL A+VFT DI K++ + +++AGTVWINCY+
Sbjct: 397 EEIFGPVQEILRFKTVDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYN 456
Query: 377 AFDAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +A +PFGG+K SG GRE+GE GL YSEVK VTIK+P K+S
Sbjct: 457 ALNAQSPFGGFKMSGNGREMGESGLREYSEVKTVTIKIPQKNS 499
>sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDHI) (ALDH-E2)
Length = 517
Score = 225 bits (573), Expect = 7e-59
Identities = 104/161 (64%), Positives = 130/161 (80%)
Frame = +2
Query: 23 DQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAKEE 202
+QGPQVD+ Q KI+ IN+GK EGA+L GG D+GYF++PT+F V D M IAKEE
Sbjct: 357 EQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEE 416
Query: 203 IFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAF 382
IFGPVMQI+KFK I+EV+ RANN+ YGLAA+VFTKD++K+ ++ Q+L+AGTVW+NCYD F
Sbjct: 417 IFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVF 476
Query: 383 DAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +PFGGYK SG GRELGEYGL Y+EVK VT+KVP K+S
Sbjct: 477 GAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS 517
>sp|P81178|ALDH2_MESAU Aldehyde dehydrogenase, mitochondrial (ALDH class 2) (ALDH1)
(ALDH-E2)
Length = 500
Score = 224 bits (572), Expect = 9e-59
Identities = 105/161 (65%), Positives = 130/161 (80%)
Frame = +2
Query: 23 DQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAKEE 202
+QGPQVD+ Q KI+ I SG+ EGA+L GG D+GYF++PT+F V D M IAKEE
Sbjct: 340 EQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEE 399
Query: 203 IFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAF 382
IFGPVMQI+KFK I+EV+ RANN++YGLAA+VFTKD++K+ ++ Q+L+AGTVWINCYD F
Sbjct: 400 IFGPVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVF 459
Query: 383 DAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +PFGGYK SG GRELGEYGL Y+EVK VTIKVP K+S
Sbjct: 460 GAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTIKVPQKNS 500
>sp|P11884|ALDH2_RAT Aldehyde dehydrogenase, mitochondrial precursor (ALDH class 2)
(ALDH1) (ALDH-E2)
Length = 519
Score = 224 bits (571), Expect = 1e-58
Identities = 104/161 (64%), Positives = 130/161 (80%)
Frame = +2
Query: 23 DQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAKEE 202
+QGPQVD+ Q KI+ I SG+ EGA+L GG D+GYF++PT+F V D M IAKEE
Sbjct: 359 EQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEE 418
Query: 203 IFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAF 382
IFGPVMQI+KFK I+EV+ RANN++YGLAA+VFTKD++K+ ++ Q+L+AGTVWINCYD F
Sbjct: 419 IFGPVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVF 478
Query: 383 DAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A +PFGGYK SG GRELGEYGL Y+EVK VT+KVP K+S
Sbjct: 479 GAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS 519
>sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
(ALHDII) (ALDH-E1)
Length = 496
Score = 224 bits (571), Expect = 1e-58
Identities = 102/161 (63%), Positives = 130/161 (80%)
Frame = +2
Query: 23 DQGPQVDKDQLNKIIDLINSGKSEGAQLCTGGKQLGDKGYFVEPTIFSKVNDNMRIAKEE 202
+QGPQ+DK+Q NKI+DLI SGK EGA+L GG G+KGYF++PT+FS V D MRIAKEE
Sbjct: 336 NQGPQIDKEQYNKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDEMRIAKEE 395
Query: 203 IFGPVMQIMKFKNIDEVIERANNNEYGLAASVFTKDIEKSMHIMQSLRAGTVWINCYDAF 382
IFGPV QIMKFK++D+VI+RANN YGL+A +FTKD++K++ + +L+AGTVW+NCY
Sbjct: 396 IFGPVQQIMKFKSLDDVIKRANNTTYGLSAGIFTKDLDKAVTVSSALQAGTVWVNCYSVV 455
Query: 383 DAAAPFGGYKASGVGRELGEYGLNNYSEVKMVTIKVPSKSS 505
A PFGG+K SG GRELGEYGL Y+EVK VT+K+ K+S
Sbjct: 456 SAQVPFGGFKMSGNGRELGEYGLQQYTEVKTVTVKISQKNS 496
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,393,802
Number of Sequences: 369166
Number of extensions: 1237432
Number of successful extensions: 3895
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3709
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3774
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4177115900
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)