Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_011_D06 (800 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O55125|NIPS1_MOUSE Protein NipSnap1 165 2e-40 sp|Q9BPW8|NIPS1_HUMAN Protein NipSnap1 164 3e-40 sp|Q9PU58|NIPS2_BRARE Protein NipSnap2 163 4e-40 sp|O75323|NIPS2_HUMAN Protein NipSnap2 (Glioblastoma amplif... 162 1e-39 sp|O55126|NIPS2_MOUSE Protein NipSnap2 (Glioblastoma amplif... 156 5e-38 sp|Q9VXK0|NIPSN_DROME Protein NipSnap 155 9e-38 sp|P34492|YMQ1_CAEEL Putative NipSnap protein K02D10.1 121 3e-27 sp|Q9UFN0|NPS3A_HUMAN Protein NipSnap3A (NipSnap4) (Target ... 54 6e-07 sp|Q5RAA9|NPS3A_PONPY Protein NipSnap3A 54 6e-07 sp|Q9CQE1|NPS3B_MOUSE Protein NipSnap3B 51 4e-06
>sp|O55125|NIPS1_MOUSE Protein NipSnap1 Length = 284 Score = 165 bits (417), Expect = 2e-40 Identities = 70/136 (51%), Positives = 103/136 (75%) Frame = +2 Query: 227 RFNSTPDFEEFRKRRNEMLVFRKTQILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIE 406 + + ++ EFRK R++ML+ R+ Q+L FS+W E +PR + +I+ELR+Y LKPGTMIE Sbjct: 141 KLKNNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPR-AGPNIYELRTYKLKPGTMIE 199 Query: 407 WGNYWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDEC 586 WGN WAR I+ R+++ E + G F+ +G++++VHH+WAYKDL+ R++ RN AWR GWDE Sbjct: 200 WGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDEN 259 Query: 587 VLHTVPLIRHMNSNIL 634 V +TVPL+RHM S I+ Sbjct: 260 VYYTVPLVRHMESRIM 275
>sp|Q9BPW8|NIPS1_HUMAN Protein NipSnap1 Length = 284 Score = 164 bits (415), Expect = 3e-40 Identities = 69/136 (50%), Positives = 102/136 (75%) Frame = +2 Query: 227 RFNSTPDFEEFRKRRNEMLVFRKTQILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIE 406 + + ++ EFR+ R++ML+ R+ Q+L FS+W E +PR + I+ELR+Y LKPGTMIE Sbjct: 141 KLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPN-IYELRTYKLKPGTMIE 199 Query: 407 WGNYWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDEC 586 WGN WAR I+ R+++ E + G F+ +G++++VHH+WAYKDL+ R++ RN AWR GWDE Sbjct: 200 WGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDEN 259 Query: 587 VLHTVPLIRHMNSNIL 634 V +TVPL+RHM S I+ Sbjct: 260 VYYTVPLVRHMESRIM 275
>sp|Q9PU58|NIPS2_BRARE Protein NipSnap2 Length = 286 Score = 163 bits (413), Expect = 4e-40 Identities = 71/136 (52%), Positives = 98/136 (72%) Frame = +2 Query: 227 RFNSTPDFEEFRKRRNEMLVFRKTQILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIE 406 + + +F E+R R +ML+ R+ Q+L FS+W E PR + I+ELRSY L+PGTMIE Sbjct: 143 KLKNNKEFLEYRSERGKMLLSRRNQLLLEFSFWNEPVPRDGPN-IYELRSYQLRPGTMIE 201 Query: 407 WGNYWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDEC 586 WGNYWAR I R+ + E + G F+ +GD++MVHH+WAYKDL+ R+ RN AW++ GWDE Sbjct: 202 WGNYWARAIGYRQHNREAVGGFFSQIGDLYMVHHLWAYKDLQSREDTRNAAWQHEGWDEV 261 Query: 587 VLHTVPLIRHMNSNIL 634 V +TVPLI+HM S I+ Sbjct: 262 VYYTVPLIQHMESRIM 277
>sp|O75323|NIPS2_HUMAN Protein NipSnap2 (Glioblastoma amplified sequence) Length = 286 Score = 162 bits (410), Expect = 1e-39 Identities = 72/136 (52%), Positives = 98/136 (72%) Frame = +2 Query: 227 RFNSTPDFEEFRKRRNEMLVFRKTQILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIE 406 + +F EFRK R++ML+ RK Q+L FS+W E PR S +I+ELRSY L+PGTMIE Sbjct: 143 KLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPR-SGPNIYELRSYQLRPGTMIE 201 Query: 407 WGNYWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDEC 586 WGNYWAR IR R+ +E + G F+ +G ++MVHH+WAY+DL+ R+ +RN AW GW+E Sbjct: 202 WGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEEL 261 Query: 587 VLHTVPLIRHMNSNIL 634 V +TVPLI+ M S I+ Sbjct: 262 VYYTVPLIQEMESRIM 277
>sp|O55126|NIPS2_MOUSE Protein NipSnap2 (Glioblastoma amplified sequence) Length = 281 Score = 156 bits (395), Expect = 5e-38 Identities = 70/136 (51%), Positives = 95/136 (69%) Frame = +2 Query: 227 RFNSTPDFEEFRKRRNEMLVFRKTQILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIE 406 + +F FRK R++ML+ RK Q+L FS+W E PR + I+ELRSY L+PGTMIE Sbjct: 138 KLKENQEFVNFRKARSDMLLSRKNQLLLEFSFWNEPVPRPGPN-IYELRSYQLRPGTMIE 196 Query: 407 WGNYWARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDEC 586 WGNYWAR IR R+ +E I G F+ +G ++MV H+WAY+DL+ R+ +RN AW GW+E Sbjct: 197 WGNYWARAIRFRQDSNEAIGGFFSQIGQLYMVDHLWAYRDLQTREDIRNAAWHKHGWEEL 256 Query: 587 VLHTVPLIRHMNSNIL 634 V +TVPLI+ M S I+ Sbjct: 257 VYYTVPLIQEMESRIM 272
>sp|Q9VXK0|NIPSN_DROME Protein NipSnap Length = 273 Score = 155 bits (393), Expect = 9e-38 Identities = 70/137 (51%), Positives = 93/137 (67%) Frame = +2 Query: 242 PDFEEFRKRRNEMLVFRKTQILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIEWGNYW 421 P++ + R++ L R Q L FSYWP+I R + +I+E+RSY L PGTMIEWGN W Sbjct: 135 PEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASR-TGKNIYEMRSYRLTPGTMIEWGNNW 193 Query: 422 ARGIRVRKQHSEPIAGLFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTV 601 AR I RK ++E AG F+ +G ++ VHH+W YK L+ RK+ R AWR+PGWDECV +TV Sbjct: 194 ARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTV 253 Query: 602 PLIRHMNSNILRATPFS 652 PLIR M+ +L T FS Sbjct: 254 PLIREMHCRVLAPTEFS 270
>sp|P34492|YMQ1_CAEEL Putative NipSnap protein K02D10.1 Length = 526 Score = 121 bits (303), Expect = 3e-27 Identities = 53/121 (43%), Positives = 79/121 (65%) Frame = +2 Query: 290 RKTQILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIEWGNYWARGIRVRKQHSEPIAG 469 RK I+ FSYW E + R + +++LRSY L+PGTMI+W + WA+GI+ R++ ++ + G Sbjct: 404 RKNLIVKSFSYWREPEQRPPNH-VYDLRSYVLQPGTMIDWASAWAKGIQYRREANQDVGG 462 Query: 470 LFTHVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATPF 649 F VG +++V+H+WAY + R R+ W PGWD V +TVPLI+ M S IL T + Sbjct: 463 FFAQVGQLYVVYHIWAYPSMSGRNDTRHATWAKPGWDATVANTVPLIKKMQSKILTPTKY 522 Query: 650 S 652 S Sbjct: 523 S 523
>sp|Q9UFN0|NPS3A_HUMAN Protein NipSnap3A (NipSnap4) (Target for Salmonella secreted protein C) (TassC) Length = 247 Score = 53.5 bits (127), Expect = 6e-07 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 2/106 (1%) Frame = +2 Query: 338 PRQSDDSIFELRSYTLKPGTMIEWGNYWARGIRVRKQHSEPIAGLFTHVGD-IHMVHHMW 514 PRQ D +E RSY LKP M E+ + + +R HSE + G ++ V H+W Sbjct: 29 PRQYDGIFYEFRSYYLKPSKMNEFLENFEKNAHLRTAHSELVGYWSVEFGGRMNTVFHIW 88 Query: 515 AYKDLEHRKKMRNEAWRNPGWDE-CVLHTVPLIRHMNSNILRATPF 649 Y + HR ++R ++ W E ++ + LI S I P+ Sbjct: 89 KYDNFAHRTEVRKALAKDKEWQEQFLIPNLALIDKQESEITYLVPW 134
Score = 40.0 bits (92), Expect = 0.007 Identities = 23/102 (22%), Positives = 49/102 (48%), Gaps = 2/102 (1%) Frame = +2 Query: 353 DSIFELRSYTLKPGTMIEWGNYWARGI--RVRKQHSEPIAGLFTHVGDIHMVHHMWAYKD 526 + ++EL ++ +KPG WG+ + R + V +++ + T G ++ VH +W + Sbjct: 143 EGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNES 202 Query: 527 LEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATPFS 652 + R R+++ +P V +V + + +L T FS Sbjct: 203 ADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFS 244
>sp|Q5RAA9|NPS3A_PONPY Protein NipSnap3A Length = 247 Score = 53.5 bits (127), Expect = 6e-07 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 2/106 (1%) Frame = +2 Query: 338 PRQSDDSIFELRSYTLKPGTMIEWGNYWARGIRVRKQHSEPIAGLFTHVGD-IHMVHHMW 514 PRQ D +E RSY LKP M E+ + + +R HSE + G ++ V H+W Sbjct: 29 PRQYDGIFYEFRSYYLKPSKMNEFLENFKKNAHLRTAHSELVGYWSVEFGGRMNTVFHIW 88 Query: 515 AYKDLEHRKKMRNEAWRNPGWDE-CVLHTVPLIRHMNSNILRATPF 649 Y + HR ++R ++ W E ++ + LI S I P+ Sbjct: 89 KYDNFAHRTEVRKALAKDKEWQEQFLIPNLALIDKQESEITYLVPW 134
Score = 40.0 bits (92), Expect = 0.007 Identities = 23/102 (22%), Positives = 49/102 (48%), Gaps = 2/102 (1%) Frame = +2 Query: 353 DSIFELRSYTLKPGTMIEWGNYWARGI--RVRKQHSEPIAGLFTHVGDIHMVHHMWAYKD 526 + ++EL ++ +KPG WG+ + R + V +++ + T G ++ VH +W + Sbjct: 143 EGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNES 202 Query: 527 LEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATPFS 652 + R R+++ +P V +V + + +L T FS Sbjct: 203 ADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFS 244
>sp|Q9CQE1|NPS3B_MOUSE Protein NipSnap3B Length = 247 Score = 50.8 bits (120), Expect = 4e-06 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Frame = +2 Query: 299 QILFPFSYWPEIKPRQSDDSIFELRSYTLKPGTMIEWGNYWARGIRVRKQHSEPIAGLFT 478 Q+ PF+ PRQS+ + +E R+Y LKP E+ + + +R HSE I G +T Sbjct: 20 QVCSPFA----TGPRQSNGTFYEFRTYFLKPSKTNEFLENFKNSVHLRTAHSEMI-GYWT 74 Query: 479 --HVGDIHMVHHMWAYKDLEHRKKMRNEAWRNPGWDE 583 G + V H+W Y + HR +R ++ W E Sbjct: 75 VEFGGRTNRVFHIWKYDNFAHRTAVRKALAKDKEWQE 111
Score = 42.4 bits (98), Expect = 0.001 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 2/102 (1%) Frame = +2 Query: 353 DSIFELRSYTLKPGTMIEWGNYWARGI--RVRKQHSEPIAGLFTHVGDIHMVHHMWAYKD 526 + ++EL ++ +KPG WGN + R + V +S + T G ++ VH +W + Sbjct: 143 EGVYELATFQMKPGGPALWGNAFKRAVNAHVELGYSTLVGVFHTEYGALNRVHVLWWNES 202 Query: 527 LEHRKKMRNEAWRNPGWDECVLHTVPLIRHMNSNILRATPFS 652 + R R+ + +P V +V + + L T FS Sbjct: 203 ADSRAAGRHWSHEDPRVVAAVRESVSYLESQQNTFLIPTSFS 244
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,949,070 Number of Sequences: 369166 Number of extensions: 1767338 Number of successful extensions: 4655 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4508 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4643 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7570361805 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)