Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_D01-2
(355 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle 132 2e-31
sp|P05661|MYSA_DROME Myosin heavy chain, muscle 131 5e-31
sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A) 112 3e-25
sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B... 108 3e-24
sp|P13539|MYH6_MESAU Myosin heavy chain, cardiac muscle alp... 105 3e-23
sp|Q02566|MYH6_MOUSE Myosin heavy chain, cardiac muscle alp... 105 4e-23
sp|P29616|MYSC_CHICK Myosin heavy chain, cardiac muscle iso... 103 9e-23
sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, a... 103 2e-22
sp|P02563|MYH6_RAT Myosin heavy chain, cardiac muscle alpha... 102 3e-22
sp|P02567|MYO1_CAEEL Myosin-1 (Myosin heavy chain D) (MHC D) 102 4e-22
>sp|P24733|MYS_AEQIR Myosin heavy chain, striated muscle
Length = 1938
Score = 132 bits (333), Expect = 2e-31
Identities = 62/116 (53%), Positives = 88/116 (75%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+NHQR+LESMQASLEAE +G+ +AM++KKKLE DINELEV LD +NR K+E EK K+YQ
Sbjct: 1585 RNHQRALESMQASLEAEAKGKADAMRIKKKLEQDINELEVALDASNRGKAEMEKTVKRYQ 1644
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
QQ+ EMQ ++E+ QR+ E + ER+ +++GE+EE+R + AE+ RKA++
Sbjct: 1645 QQIREMQTSIEEEQRQRDEARESYNMAERRCTLMSGEVEELRAALEQAERARKASD 1700
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/116 (31%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Frame = +3
Query: 3 KNHQRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
KN + ++ Q L EAE KM +KLE ++ELE LD R +E +KN +K
Sbjct: 1781 KNLESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKA 1840
Query: 180 QQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCD-HAEKNRKA 344
++L E+ Q DE +E + E + K+ ++EE + + K RKA
Sbjct: 1841 DRRLKELAFQADEDRKNQERLQELIDKLNAKIKTFKRQVEEAEEIAAINLAKYRKA 1896
Score = 53.1 bits (126), Expect = 2e-07
Identities = 29/105 (27%), Positives = 55/105 (52%)
Frame = +3
Query: 39 SLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDE 218
SL+AE K+K KLE ++ELE L+ +++ + EK +K +Q L Q V++
Sbjct: 1006 SLQAEEDKCNHLNKLKAKLEQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVED 1065
Query: 219 QHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAEA 353
+ + E + E +++ LN +LE+ +N+ ++ K +A
Sbjct: 1066 LERVKRELEENVRRKEAEISSLNSKLEDEQNLVSQLQRKIKELQA 1110
Score = 52.0 bits (123), Expect = 4e-07
Identities = 24/109 (22%), Positives = 60/109 (55%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
+++L+ ++ +LE E + R + K K+K+E D+ + ++ R+K E E+N ++ + ++
Sbjct: 1025 EQALDELEDNLEREKKVRGDVEKAKRKVEQDLKSTQENVEDLERVKRELEENVRRKEAEI 1084
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
+ ++++++ + + ++ + ++ L ELE RN EK R
Sbjct: 1085 SSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAKVEKQR 1133
Score = 39.3 bits (90), Expect = 0.003
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 7/119 (5%)
Frame = +3
Query: 3 KNHQRS---LESMQASLEAE----VRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQE 161
++ QRS L+S ++ L+AE R +A L + ++L L+ A R E+
Sbjct: 1261 EDSQRSINELQSQKSRLQAENSDLTRQLEDAEHRVSVLSKEKSQLSSQLEDARRSLEEET 1320
Query: 162 KNTKKYQQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
+ K Q ++ M A +D Q E E +R+L+ N E+++ R+ + NR
Sbjct: 1321 RARSKLQNEVRNMHADMDAIREQLEEEQESKSDVQRQLSKANNEIQQWRSKFESEGANR 1379
Score = 38.5 bits (88), Expect = 0.005
Identities = 24/112 (21%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
Frame = +3
Query: 21 LESMQASLEAEVRGRTEAMK-MKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVE 197
++ ++ E+E RTE ++ K+KL ++E E + AN S EK + QQ+L +
Sbjct: 1365 IQQWRSKFESEGANRTEELEDQKRKLLGKLSEAEQTTEAANAKCSALEKAKSRLQQELED 1424
Query: 198 MQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAEA 353
M +VD + + ++ ++ A ++ +++ ++++K + A
Sbjct: 1425 MSIEVDRANASVNQMEKKQRAFDKTTAEWQAKVNSLQSELENSQKESRGYSA 1476
Score = 38.1 bits (87), Expect = 0.006
Identities = 22/104 (21%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
Frame = +3
Query: 45 EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDEQH 224
EA ++ + ++KK + NE+ +D ++KS+ EK+ K ++++ ++++Q+
Sbjct: 1177 EASLQHEAQISALRKKHQDAANEMADQVDQLQKVKSKLEKDKKDLKREMDDLESQMTHNM 1236
Query: 225 HQRELVSEQLGITERKLAMLNGELEEVRNMCD--HAEKNRKAAE 350
+ + + E +++ LN LE+ + + ++K+R AE
Sbjct: 1237 KNKGCSEKVMKQFESQMSDLNARLEDSQRSINELQSQKSRLQAE 1280
Score = 34.3 bits (77), Expect = 0.090
Identities = 23/100 (23%), Positives = 46/100 (46%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+ + + S+ + LE E ++ + K+L+ I ELE L+ +++ EK +
Sbjct: 1078 RRKEAEISSLNSKLEDEQNLVSQLQRKIKELQARIEELEEELEAERNARAKVEKQRAELN 1137
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEE 302
++L E+ ++DE E E +L + +LEE
Sbjct: 1138 RELEELGERLDEAGGATSAQIELNKKREAELLKIRRDLEE 1177
Score = 28.9 bits (63), Expect = 3.8
Identities = 24/119 (20%), Positives = 50/119 (42%), Gaps = 7/119 (5%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
K + ++ M+ L R + E + L N+L + L T +QE+ +K
Sbjct: 847 KEQLKQMDKMKEDLAKTERIKKELEEQNVTLLEQKNDLFLQLQTLEDSMGDQEERVEKLI 906
Query: 183 QQLVEMQAQVDEQHH----QRELVSEQLGI---TERKLAMLNGELEEVRNMCDHAEKNR 338
Q + ++Q+ E + + ++ GI E A L ++ ++ N AE+++
Sbjct: 907 MQKADFESQIKELEERLLDEEDAAADLEGIKKKMEADNANLKKDIGDLENTLQKAEQDK 965
Score = 28.5 bits (62), Expect = 5.0
Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 29/118 (24%)
Frame = +3
Query: 84 KKKLEHDINELEVGLD----------------------TANRLKSEQ------EKNTKKY 179
K+KLE DIN ++ LD A+ L++EQ EK K
Sbjct: 1724 KRKLEGDINAMQTDLDEMHGELKGADERCKKAMADAARLADELRAEQDHSNQVEKVRKNL 1783
Query: 180 QQQLVEMQAQVDE-QHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
+ Q+ E Q ++DE + + + + E ++ L EL+ + +KN + A+
Sbjct: 1784 ESQVKEFQIRLDEAEASSLKGGKKMIQKLESRVHELEAELDNEQRRHAETQKNMRKAD 1841
>sp|P05661|MYSA_DROME Myosin heavy chain, muscle
Length = 1962
Score = 131 bits (329), Expect = 5e-31
Identities = 63/116 (54%), Positives = 87/116 (75%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
KNHQR+L+SMQASLEAE +G+ EA++MKKKLE DINELE+ LD AN+ +E +KN K+YQ
Sbjct: 1587 KNHQRALDSMQASLEAEAKGKAEALRMKKKLEADINELEIALDHANKANAEAQKNIKRYQ 1646
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
QQL ++Q ++E+ R+ EQLGI+ER+ L ELEE R + + A++ R+ AE
Sbjct: 1647 QQLKDIQTALEEEQRARDDAREQLGISERRANALQNELEESRTLLEQADRGRRQAE 1702
Score = 45.1 bits (105), Expect = 5e-05
Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 2/115 (1%)
Frame = +3
Query: 12 QRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQ 188
++ ++ +Q L EAE K +KLE + ELE LD R ++ +KN +K +++
Sbjct: 1786 EQQIKELQVRLDEAEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSERR 1845
Query: 189 LVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCD-HAEKNRKAAE 350
+ E+ Q +E E + + + ++K+ ++EE + + K RKA +
Sbjct: 1846 VKELSFQSEEDRKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQ 1900
Score = 43.9 bits (102), Expect = 1e-04
Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 21/126 (16%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTK------ 173
+++L+ ++ SLE E + R + K K+K+E D+ + + R K E E+ +
Sbjct: 1027 EQTLDELEDSLEREKKVRGDVEKSKRKVEGDLKLTQEAVADLERNKKELEQTIQRKDKEL 1086
Query: 174 ---------------KYQQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVR 308
K+Q+Q+ E+QA+++E + E + E++ A L ELEE+
Sbjct: 1087 SSITAKLEDEQVVVLKHQRQIKELQARIEELEEEVEAERQARAKAEKQRADLARELEELG 1146
Query: 309 NMCDHA 326
+ A
Sbjct: 1147 ERLEEA 1152
Score = 38.1 bits (87), Expect = 0.006
Identities = 23/100 (23%), Positives = 55/100 (55%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+ +Q++ E +QA+ E ++ K+K KLE ++ELE L+ +++ + EK+ +K +
Sbjct: 1000 ETNQKTGEELQAA-EDKIN---HLNKVKAKLEQTLDELEDSLEREKKVRGDVEKSKRKVE 1055
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEE 302
L Q V + ++ + + + +++L+ + +LE+
Sbjct: 1056 GDLKLTQEAVADLERNKKELEQTIQRKDKELSSITAKLED 1095
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Frame = +3
Query: 78 KMKKKLEHD-------INELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDEQHHQRE 236
K+K K EHD +N+ D R K+ QEK K+ Q L E+Q+++DE +
Sbjct: 1211 KLKAKAEHDRQTCHNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNR--- 1267
Query: 237 LVSEQLGITERKLAMLNGEL 296
+++KL++ N +L
Sbjct: 1268 -TLNDFDASKKKLSIENSDL 1286
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/94 (25%), Positives = 51/94 (54%)
Frame = +3
Query: 57 RGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDEQHHQRE 236
R + K+ K+L+H +NE++ LD NR ++ + + KK + ++ Q++E Q
Sbjct: 1239 RDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKKKLSIENSDLLRQLEEAESQ-- 1296
Query: 237 LVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
VS+ +++ K++ L +LE+ + + D + R
Sbjct: 1297 -VSQ---LSKIKIS-LTTQLEDTKRLADEESRER 1325
Score = 30.4 bits (67), Expect = 1.3
Identities = 30/129 (23%), Positives = 53/129 (41%), Gaps = 21/129 (16%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMK---------------------MKKKLEHDINELEVGL 128
Q LE + LE RGR +A + K+KLE ++ L L
Sbjct: 1681 QNELEESRTLLEQADRGRRQAEQELADAHEQLNEVSAQNASISAAKRKLESELQTLHSDL 1740
Query: 129 DTANRLKSEQEKNTKKYQQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVR 308
D L +E + + +K ++ +V+ DE +++ Q E+ L +++E++
Sbjct: 1741 D---ELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQ----EKLRKALEQQIKELQ 1793
Query: 309 NMCDHAEKN 335
D AE N
Sbjct: 1794 VRLDEAEAN 1802
Score = 30.4 bits (67), Expect = 1.3
Identities = 25/114 (21%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
+ L+++ + L+ + + + KK D L L QEK K +QQ+
Sbjct: 1730 ESELQTLHSDLDELLNEAKNSEEKAKKAMVDAARLADELRAEQDHAQTQEKLRKALEQQI 1789
Query: 192 VEMQAQVDE-QHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
E+Q ++DE + + + + + E+++ L EL+ + A+KN + +E
Sbjct: 1790 KELQVRLDEAEANALKGGKKAIQKLEQRVRELENELDGEQRRHADAQKNLRKSE 1843
Score = 30.0 bits (66), Expect = 1.7
Identities = 23/114 (20%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Frame = +3
Query: 3 KNHQRSLESMQASLE-AEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
K + L ++ LE A ++ + ++KK + E+ +D N+LK++ E + +
Sbjct: 1164 KKREAELSKLRRDLEEANIQHESTLANLRKKHNDAVAEMAEQVDQLNKLKAKAEHDRQTC 1223
Query: 180 QQQLVEMQAQVDEQHHQR---ELVSEQLGITERKLAMLNGELEEVRNMCDHAEK 332
+L + + D+ + E +++QL T ++ E N D ++K
Sbjct: 1224 HNELNQTRTACDQLGRDKAAQEKIAKQLQHTLNEVQSKLDETNRTLNDFDASKK 1277
>sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A)
Length = 1969
Score = 112 bits (279), Expect = 3e-25
Identities = 53/117 (45%), Positives = 84/117 (71%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+NHQR+LESMQA+LEAE + + EA+++KKKLE DIN+LE+ LD ANR ++ +K KKY
Sbjct: 1601 RNHQRALESMQATLEAETKQKEEALRIKKKLESDINDLEIALDHANRAYADAQKTIKKYM 1660
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAEA 353
+ + E+Q Q++E+ Q++ + EQ +E++ A+L E +E+ + AE+ R+ AEA
Sbjct: 1661 ETVQELQFQIEEEQRQKDEIREQFLASEKRNAILQSEKDELAQQAEAAERARRNAEA 1717
Score = 45.1 bits (105), Expect = 5e-05
Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 21/138 (15%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
K H S+ + LE + + ++ K KL+ D+ E + D+ R + + EK K +
Sbjct: 1207 KRHGDSVAELTEQLETLQKLKAKSEAEKSKLQRDLEESQHATDSEVRSRQDLEKALKTIE 1266
Query: 183 QQLVEMQAQVDEQHHQ---------------------RELVSEQLGITERKLAMLNGELE 299
Q E+Q + DEQ Q E + QL R + L +L+
Sbjct: 1267 VQYSELQTKADEQSRQLQDFAALKNRLNNENSDLNRSLEEMDNQLNSLHRLKSTLQSQLD 1326
Query: 300 EVRNMCDHAEKNRKAAEA 353
E R D + R+A A
Sbjct: 1327 ETRRNYDEESRERQALAA 1344
Score = 43.5 bits (101), Expect = 1e-04
Identities = 28/100 (28%), Positives = 45/100 (45%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
K+ + S + L++E K++ KLE ++ELE +D R + + EK +K +
Sbjct: 1010 KHQEESNRKLNEDLQSEEDKVNHLEKIRNKLEQQMDELEENIDREKRSRGDIEKAKRKVE 1069
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEE 302
L Q +DE Q+ V L E L N +L E
Sbjct: 1070 GDLKVAQENIDEITKQKHDVETTLKRKEEDLHHTNAKLAE 1109
Score = 38.9 bits (89), Expect = 0.004
Identities = 34/119 (28%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Frame = +3
Query: 12 QRSLESMQASLEAE----VRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKK- 176
Q++L+ +A+LEAE +R + E +++ ++E I E K E+ +NT++
Sbjct: 1554 QKALDEAEAALEAEEAKVLRAQIEVSQIRSEIEKRIQE-----------KEEEFENTRRN 1602
Query: 177 YQQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAEA 353
+Q+ L MQA ++ + Q+E E L I ++ L ++ ++ DHA NR A+A
Sbjct: 1603 HQRALESMQATLEAETKQKE---EALRIKKK----LESDINDLEIALDHA--NRAYADA 1652
>sp|P02566|MYO4_CAEEL Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated protein 54)
Length = 1966
Score = 108 bits (271), Expect = 3e-24
Identities = 55/116 (47%), Positives = 78/116 (67%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
KNH R+LESMQASLE E +G+ E +++KKKLE DINELE+ LD AN+ ++ +KN K+YQ
Sbjct: 1600 KNHARALESMQASLETEAKGKAELLRIKKKLEGDINELEIALDHANKANADAQKNLKRYQ 1659
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
+Q+ E+Q QV+E+ EQ E++ +L E EE+ + AE+ RK AE
Sbjct: 1660 EQVRELQLQVEEEQRNGADTREQFFNAEKRATLLQSEKEELLVANEAAERARKQAE 1715
Score = 50.4 bits (119), Expect = 1e-06
Identities = 25/107 (23%), Positives = 58/107 (54%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
+++L+ ++ SLE E R R + K K+K+E ++ + +D + R + + E N KK + +L
Sbjct: 1040 EQTLDDLEDSLEREKRARADLDKQKRKVEGELKIAQENIDESGRQRHDLENNLKKKESEL 1099
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEK 332
+ ++++++ + Q+ + +++ L ELE R A++
Sbjct: 1100 HSVSSRLEDEQALVSKLQRQIKDGQSRISELEEELENERQSRSKADR 1146
Score = 45.4 bits (106), Expect = 4e-05
Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
KN+Q E +Q SLE E+ G+ E ++ K DI + + + LK+++ ++ K+ Q
Sbjct: 1346 KNYQHEAEQLQESLEEEIEGKNEILRQLSKANADIQQWKARFEGEGLLKADELEDAKRRQ 1405
Query: 183 -QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRK 341
Q++ E+Q +D + + + + L ++E + EK +K
Sbjct: 1406 AQKINELQEALDAANSKNASLEKTKSRLVGDLDDAQVDVERANGVASALEKKQK 1459
Score = 45.1 bits (105), Expect = 5e-05
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 1/107 (0%)
Frame = +3
Query: 3 KNHQRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
K ++ L+ +Q L EAE K+ KLE + ELE LD R + KN +
Sbjct: 1796 KGLEQQLKEIQVRLDEAEAAALKGGKKVIAKLEQRVRELESELDGEQRRFQDANKNLGRA 1855
Query: 180 QQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCD 320
+++ E+Q QVDE E + + + ++KL ++EE + +
Sbjct: 1856 DRRVRELQFQVDEDKKNFERLQDLIDKLQQKLKTQKKQVEEAEELAN 1902
Score = 42.7 bits (99), Expect = 3e-04
Identities = 33/138 (23%), Positives = 54/138 (39%), Gaps = 21/138 (15%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
K H ++ + L+ + + + K K + D +L LD K EK K+++
Sbjct: 1206 KKHTDAVAELTDQLDQLNKAKAKVEKDKAQAVRDAEDLAAQLDQETSGKLNNEKLAKQFE 1265
Query: 183 QQLVEMQAQVDEQHHQ-------------------REL--VSEQLGITERKLAMLNGELE 299
QL E+Q++ DEQ Q R+L Q+ R + L +LE
Sbjct: 1266 LQLTELQSKADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAESQVNQLTRLKSQLTSQLE 1325
Query: 300 EVRNMCDHAEKNRKAAEA 353
E R D + R+ A
Sbjct: 1326 EARRTADEEARERQTVAA 1343
Score = 36.6 bits (83), Expect = 0.018
Identities = 27/100 (27%), Positives = 48/100 (48%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
K + L S+ + LE E ++ + K + I+ELE L+ + +S+ ++ Q
Sbjct: 1093 KKKESELHSVSSRLEDEQALVSKLQRQIKDGQSRISELEEELENERQSRSKADRAKSDLQ 1152
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEE 302
++L E+ ++DEQ E E +LA L +LEE
Sbjct: 1153 RELEELGEKLDEQGGATAAQVEVNKKREAELAKLRRDLEE 1192
Score = 31.6 bits (70), Expect = 0.59
Identities = 21/100 (21%), Positives = 43/100 (43%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
K + L +Q+ + + R + +K +L + +L L+ A ++ + +
Sbjct: 1262 KQFELQLTELQSKADEQSRQLQDFTSLKGRLHSENGDLVRQLEDAESQVNQLTRLKSQLT 1321
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEE 302
QL E + DE+ +R+ V+ Q + + L LEE
Sbjct: 1322 SQLEEARRTADEEARERQTVAAQAKNYQHEAEQLQESLEE 1361
>sp|P13539|MYH6_MESAU Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1939
Score = 105 bits (262), Expect = 3e-23
Identities = 50/116 (43%), Positives = 78/116 (67%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+NH R ++S+Q SL+AE R R EA+++KKK+E D+NE+E+ L ANR+ SE +K+ K Q
Sbjct: 1590 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQ 1649
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
L + Q Q+D+ H + + E + I ER+ +L ELEE+R + + E++RK AE
Sbjct: 1650 AHLKDTQLQLDDALHANDDLKENIAIVERRNTLLQAELEELRAVVEQTERSRKLAE 1705
Score = 41.6 bits (96), Expect = 6e-04
Identities = 24/109 (22%), Positives = 54/109 (49%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
++ ++ ++ SLE E + R + + K+KLE D+N + + K + E+ KK + +
Sbjct: 1030 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLNVTQESIMDLENDKLQLEEKLKKKEFDI 1089
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
+ ++++++ + ++L + ++ L ELE R EK R
Sbjct: 1090 SQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138
Score = 37.4 bits (85), Expect = 0.011
Identities = 32/131 (24%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Frame = +3
Query: 3 KNHQRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
KN +++++ +Q L EAE K +KLE + ELE L+ + +E K +K
Sbjct: 1786 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1845
Query: 180 QQQLVEMQAQVDEQ---------------------HHQRELVSEQLGITERKLAMLNGEL 296
++++ E+ Q +E Q E EQ K + EL
Sbjct: 1846 ERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL 1905
Query: 297 EEVRNMCDHAE 329
+E D AE
Sbjct: 1906 DEAEERADIAE 1916
Score = 32.3 bits (72), Expect = 0.34
Identities = 22/85 (25%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Frame = +3
Query: 87 KKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDE-----QHHQRELVSEQ 251
K L+ +I++L L + E EK K+ + + +E+Q+ ++E +H + +++ Q
Sbjct: 1505 KNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKMELQSALEEAEASLEHEEGKILRAQ 1564
Query: 252 LGIT------ERKLAMLNGELEEVR 308
L ERKLA + E+E+ +
Sbjct: 1565 LEFNQIKAEIERKLAEKDEEMEQAK 1589
Score = 27.7 bits (60), Expect = 8.5
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Frame = +3
Query: 6 NHQRSLESMQASLEAEVRGRT-EAMKMKKKLEHDINELEVGLDTANRLKSEQ------EK 164
N ++ +E+ L+ EV E ++K + I + + A LK EQ E+
Sbjct: 1727 NQKKKMEADLTQLQTEVEEAVQECRNAEEKAKKAITDAAM---MAEELKKEQDTSAHLER 1783
Query: 165 NTKKYQQQLVEMQAQVDEQHHQRELVSEQLGIT--ERKLAMLNGELEEVRNMCDHAEKNR 338
K +Q + ++Q ++DE +EQ+ + +++L L + E+ N + AE+ R
Sbjct: 1784 MKKNMEQTIKDLQHRLDE--------AEQIALKGGKKQLQKLEARVRELENELE-AEQKR 1834
Query: 339 KA 344
A
Sbjct: 1835 NA 1836
>sp|Q02566|MYH6_MOUSE Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1938
Score = 105 bits (261), Expect = 4e-23
Identities = 50/116 (43%), Positives = 78/116 (67%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+NH R ++S+Q SL+AE R R EA+++KKK+E D+NE+E+ L ANR+ SE +K+ K Q
Sbjct: 1590 RNHLRMVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNSQ 1649
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
L + Q Q+D+ H + + E + I ER+ +L ELEE+R + + E++RK AE
Sbjct: 1650 AHLKDTQLQLDDAVHANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
Score = 38.9 bits (89), Expect = 0.004
Identities = 23/109 (21%), Positives = 53/109 (48%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
++ ++ ++ SLE E + R + + K+KLE D+ + + K + E+ KK + +
Sbjct: 1030 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDI 1089
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
+ ++++++ + ++L + ++ L ELE R EK R
Sbjct: 1090 SQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1138
Score = 37.4 bits (85), Expect = 0.011
Identities = 32/131 (24%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Frame = +3
Query: 3 KNHQRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
KN +++++ +Q L EAE K +KLE + ELE L+ + +E K +K
Sbjct: 1786 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1845
Query: 180 QQQLVEMQAQVDEQ---------------------HHQRELVSEQLGITERKLAMLNGEL 296
++++ E+ Q +E Q E EQ K + EL
Sbjct: 1846 ERRIKELTYQTEEDKKNLMRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL 1905
Query: 297 EEVRNMCDHAE 329
+E D AE
Sbjct: 1906 DEAEERADIAE 1916
Score = 32.3 bits (72), Expect = 0.34
Identities = 22/85 (25%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Frame = +3
Query: 87 KKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDE-----QHHQRELVSEQ 251
K L+ +I++L L + E EK K+ + + +E+Q+ ++E +H + +++ Q
Sbjct: 1505 KNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ 1564
Query: 252 LGIT------ERKLAMLNGELEEVR 308
L ERKLA + E+E+ +
Sbjct: 1565 LEFNQIKAEIERKLAEKDEEMEQAK 1589
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Frame = +3
Query: 6 NHQRSLESMQASLEAEVRGRT-EAMKMKKKLEHDINELEVGLDTANRLKSEQ------EK 164
N ++ +ES L+ EV E ++K + I + + A LK EQ E+
Sbjct: 1727 NQKKKMESDLTQLQTEVEEAVQECRNAEEKAKKAITDAAM---MAEELKKEQDTSAHLER 1783
Query: 165 NTKKYQQQLVEMQAQVDEQHHQRELVSEQLGIT--ERKLAMLNGELEEVRNMCDHAEKNR 338
K +Q + ++Q ++DE +EQ+ + +++L L + E+ N + AE+ R
Sbjct: 1784 MKKNMEQTIKDLQHRLDE--------AEQIALKGGKKQLQKLEARVRELENELE-AEQKR 1834
Query: 339 KA 344
A
Sbjct: 1835 NA 1836
>sp|P29616|MYSC_CHICK Myosin heavy chain, cardiac muscle isoform
Length = 1102
Score = 103 bits (258), Expect = 9e-23
Identities = 48/116 (41%), Positives = 81/116 (69%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+N QR+++S+Q++L++E R R EA+++KKK+E D+NE+E+ L ANR +E K+ + Q
Sbjct: 754 RNQQRTIDSLQSTLDSEARSRNEAIRLKKKMEGDLNEMEIQLSHANRHAAEATKSARGLQ 813
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
Q+ E+Q Q+D+ H E + EQL +++R+ +L EL+E+R + D E+ RK AE
Sbjct: 814 TQIKELQVQLDDLGHLNEDLKEQLAVSDRRNNLLQSELDELRALLDQTERARKLAE 869
Score = 39.7 bits (91), Expect = 0.002
Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Frame = +3
Query: 3 KNHQRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
KN +++++ +Q L EAE K +KLE + ELE L+ R S+ +K +K+
Sbjct: 950 KNMEQTIKDLQKRLDEAEQIALKGGKKQIQKLESRVRELENELENELRRNSDAQKGARKF 1009
Query: 180 QQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCD-HAEKNRK 341
++++ E+ Q +E + + + + K+ + EE + + K RK
Sbjct: 1010 ERRIKELTYQSEEDKKNLARMQDLIDKLQLKVKSYKHQAEEAEAQANLYLSKYRK 1064
Score = 39.3 bits (90), Expect = 0.003
Identities = 22/109 (20%), Positives = 55/109 (50%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
++ ++ ++ SLE E + R + + K+KLE D+ + + K + E+ KK + ++
Sbjct: 194 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESVMDLENDKLQMEEKLKKKEFEM 253
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
++ ++++++ + +++ + ++ L ELE R EK R
Sbjct: 254 SQLNSKIEDEQAIVMQLQKKIKELQARIEELEEELEAERAARAKVEKQR 302
Score = 39.3 bits (90), Expect = 0.003
Identities = 26/108 (24%), Positives = 50/108 (46%)
Frame = +3
Query: 21 LESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEM 200
++ + A++E V+G+ A K+ E +NE + LD RL ++ K Q + E
Sbjct: 394 VDDLTANMEQTVKGKANAEKLWGTYEDHLNETKTKLDEMTRLMNDLTTQKTKLQSENGEF 453
Query: 201 QAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKA 344
Q++E + L+S+ R ++EE+R + K++ A
Sbjct: 454 VRQLEE---KESLISQ----LSRGKTSFTQQIEELRRQLEEETKSKNA 494
Score = 36.6 bits (83), Expect = 0.018
Identities = 25/103 (24%), Positives = 44/103 (42%)
Frame = +3
Query: 21 LESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEM 200
+ ++ LE E+R ++A K +K E I EL + E +KN + Q + ++
Sbjct: 985 VRELENELENELRRNSDAQKGARKFERRIKELTYQSE-------EDKKNLARMQDLIDKL 1037
Query: 201 QAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAE 329
Q +V HQ E Q + K +L++ + AE
Sbjct: 1038 QLKVKSYKHQAEEAEAQANLYLSKYRKQQHDLDDAEERAEIAE 1080
Score = 31.6 bits (70), Expect = 0.59
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
++ E QA LEA + EA + +L N E LD LK E K Q+++
Sbjct: 623 KQKYEESQAELEASQK---EARSLSTELFKLKNAYEETLDHLETLKREN----KNLQEEI 675
Query: 192 VEMQAQVDEQH---HQRELVSEQLGITERKLAMLNGELEEVRNMCDHAE 329
++ Q+ E + H+ E V +Q+ E++ + + LEE +H E
Sbjct: 676 SDLTNQISEGNKNLHEIEKVKKQV---EQEKSEVQLALEEAEGALEHEE 721
Score = 30.8 bits (68), Expect = 1.0
Identities = 24/113 (21%), Positives = 49/113 (43%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
Q L+ ++A L+ R R K EH++ E ++ + + KK + +
Sbjct: 848 QSELDELRALLDQTERAR-------KLAEHELLEATERVNLLHTQNTSLINQKKKLEGDI 900
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
+MQ +V+E + ++ AM+ EL++ ++ H E+ +K E
Sbjct: 901 SQMQNEVEESIQECRNAEQKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 953
>sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, adult
Length = 1939
Score = 103 bits (256), Expect = 2e-22
Identities = 48/116 (41%), Positives = 79/116 (68%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+NH R +ESMQ++L+AE+R R EA+++KKK+E D+NE+E+ L ANR+ +E +KN + Q
Sbjct: 1591 RNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRMAAEAQKNLRNTQ 1650
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
L + Q +D+ +E + EQ+ + ER+ +L E+EE+R + E++RK AE
Sbjct: 1651 GTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQTERSRKVAE 1706
Score = 40.4 bits (93), Expect = 0.001
Identities = 22/109 (20%), Positives = 56/109 (51%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
++ ++ ++ SLE E + R + + K+KLE D+ + K + ++ KK ++
Sbjct: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEI 1090
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
++Q++++++ + +++ + ++ L E+E R AEK+R
Sbjct: 1091 SQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHR 1139
Score = 39.3 bits (90), Expect = 0.003
Identities = 32/131 (24%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Frame = +3
Query: 3 KNHQRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
KN ++++ + L EAE K +KLE + ELE +D+ + +E K +KY
Sbjct: 1787 KNMDQTVKDLHVRLDEAEQLALKGGKKQLQKLEARVRELEGEVDSEQKRSAEAVKGVRKY 1846
Query: 180 QQQLVEMQAQVDEQH---------------------HQRELVSEQLGITERKLAMLNGEL 296
++++ E+ Q +E Q E E + K + EL
Sbjct: 1847 ERRVKELTYQCEEDRKNILRLQDLVDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHEL 1906
Query: 297 EEVRNMCDHAE 329
EE D AE
Sbjct: 1907 EEAEERADIAE 1917
>sp|P02563|MYH6_RAT Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length = 1938
Score = 102 bits (254), Expect = 3e-22
Identities = 49/116 (42%), Positives = 77/116 (66%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
+NH R ++S+Q SL+AE R R EA+++KKK+E D+NE+E+ L ANR+ SE +K+ K Q
Sbjct: 1589 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQ 1648
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
L + Q Q+D+ + + E + I ER+ +L ELEE+R + + E++RK AE
Sbjct: 1649 AHLKDTQLQLDDAVRANDDLKENIAIVERRNTLLQAELEELRAVVEQTERSRKLAE 1704
Score = 38.9 bits (89), Expect = 0.004
Identities = 23/109 (21%), Positives = 53/109 (48%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQL 191
++ ++ ++ SLE E + R + + K+KLE D+ + + K + E+ KK + +
Sbjct: 1029 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDI 1088
Query: 192 VEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNR 338
+ ++++++ + ++L + ++ L ELE R EK R
Sbjct: 1089 SQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLR 1137
Score = 37.4 bits (85), Expect = 0.011
Identities = 32/131 (24%), Positives = 52/131 (39%), Gaps = 22/131 (16%)
Frame = +3
Query: 3 KNHQRSLESMQASL-EAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKY 179
KN +++++ +Q L EAE K +KLE + ELE L+ + +E K +K
Sbjct: 1785 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1844
Query: 180 QQQLVEMQAQVDEQ---------------------HHQRELVSEQLGITERKLAMLNGEL 296
++++ E+ Q +E Q E EQ K + EL
Sbjct: 1845 ERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHEL 1904
Query: 297 EEVRNMCDHAE 329
+E D AE
Sbjct: 1905 DEAEERADIAE 1915
Score = 32.3 bits (72), Expect = 0.34
Identities = 22/85 (25%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Frame = +3
Query: 87 KKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDE-----QHHQRELVSEQ 251
K L+ +I++L L + E EK K+ + + +E+Q+ ++E +H + +++ Q
Sbjct: 1504 KNLQEEISDLTEQLGEGGKNVHELEKIRKQLEVEKLELQSALEEAEASLEHEEGKILRAQ 1563
Query: 252 LGIT------ERKLAMLNGELEEVR 308
L ERKLA + E+E+ +
Sbjct: 1564 LEFNQIKAEIERKLAEKDEEMEQAK 1588
>sp|P02567|MYO1_CAEEL Myosin-1 (Myosin heavy chain D) (MHC D)
Length = 1938
Score = 102 bits (253), Expect = 4e-22
Identities = 50/116 (43%), Positives = 77/116 (66%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
KNHQR+LES+QASLE E + + E + KKKLE DIN+LE+ LD AN+ + +KN KK
Sbjct: 1595 KNHQRALESIQASLETEAKSKAELARAKKKLETDINQLEIALDHANKANVDAQKNLKKLF 1654
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRKAAE 350
Q+ E+Q QVD++ +RE + E E++LA+ E E++ + + ++K++K E
Sbjct: 1655 DQVKELQGQVDDEQRRREEIRENYLAAEKRLAIALSESEDLAHRIEASDKHKKQLE 1710
Score = 43.1 bits (100), Expect = 2e-04
Identities = 21/76 (27%), Positives = 46/76 (60%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
KN+ + + ++ +L+A + + + K K L+ +++++ +D + + EQE+ K+Y+
Sbjct: 1202 KNNDQ-ISALTNTLDALQKSKAKIEKEKGVLQKELDDINAQVDQETKSRVEQERLAKQYE 1260
Query: 183 QQLVEMQAQVDEQHHQ 230
Q+ E+Q +VDEQ Q
Sbjct: 1261 IQVAELQQKVDEQSRQ 1276
Score = 41.2 bits (95), Expect = 7e-04
Identities = 23/100 (23%), Positives = 50/100 (50%)
Frame = +3
Query: 42 LEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQQQLVEMQAQVDEQ 221
L+AE + +A +++ KLE ++E+E ++ R+++E EK+ +K + +L Q +DE
Sbjct: 1017 LQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQETIDEL 1076
Query: 222 HHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEKNRK 341
+ L E + L +E+ + + + + K
Sbjct: 1077 SAIKLETDASLKKKEADIHALGVRIEDEQALANRLTRQSK 1116
Score = 37.7 bits (86), Expect = 0.008
Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 5/106 (4%)
Frame = +3
Query: 12 QRSLESMQASLEAEVRGRTEAM-----KMKKKLEHDINELEVGLDTANRLKSEQEKNTKK 176
++SLE L+A++ AM K K+E + LE L + R E K K
Sbjct: 1790 RKSLELNAKELQAKIDDAERAMIQFGAKALAKVEDRVRSLEAELHSEQRRHQESIKGYTK 1849
Query: 177 YQQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNM 314
+++ E+Q QV+E + + E + ++K+ + ++EE +
Sbjct: 1850 QERRARELQFQVEEDKKAFDRLQENVEKLQQKIRVQKRQIEEAEEV 1895
Score = 34.3 bits (77), Expect = 0.090
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 7/117 (5%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHD-------INELEVGLDTANRLKSEQE 161
K ++ + +Q ++ + R E K +L +D + ELE+ L T NR K+
Sbjct: 1257 KQYEIQVAELQQKVDEQSRQIGEYTSTKGRLSNDNSDLARQVEELEIHLATINRAKTA-- 1314
Query: 162 KNTKKYQQQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCDHAEK 332
+ QLVE + +++ H+R+ E +L + LEE N D ++
Sbjct: 1315 -----FSSQLVEAKKAAEDELHERQEFHAACKNLEHELDQCHELLEEQINGKDDIQR 1366
Score = 33.1 bits (74), Expect = 0.20
Identities = 21/106 (19%), Positives = 51/106 (48%)
Frame = +3
Query: 3 KNHQRSLESMQASLEAEVRGRTEAMKMKKKLEHDINELEVGLDTANRLKSEQEKNTKKYQ 182
K + + ++ +E E + K+ I E+E L+ + +S+ ++ + Q
Sbjct: 1088 KKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQSRSKADRARAELQ 1147
Query: 183 QQLVEMQAQVDEQHHQRELVSEQLGITERKLAMLNGELEEVRNMCD 320
++L E+ ++DEQ+ Q E+ + + ++ +L+E +NM +
Sbjct: 1148 RELDELNERLDEQNKQLEIQQDNNKKKDSEIIKFRRDLDE-KNMAN 1192
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,224,189
Number of Sequences: 369166
Number of extensions: 367795
Number of successful extensions: 3777
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2764
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3623
length of database: 68,354,980
effective HSP length: 85
effective length of database: 52,652,505
effective search space used: 1684880160
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)