Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_C23
(875 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8IN94|OSA_DROME Trithorax group protein osa (Eyelid pro... 140 4e-33
sp|Q8NFD5|ARI1B_HUMAN AT-rich interactive domain-containing... 112 1e-24
sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing... 105 2e-22
sp|O43156|K0406_HUMAN Protein KIAA0406 35 0.36
sp|P78025|LON_MYCPN ATP-dependent protease La 32 2.3
sp|Q7V697|HEM3_PROMM Porphobilinogen deaminase (PBG) (Hydro... 31 5.2
sp|Q91V83|K0406_MOUSE Protein KIAA0406 homolog 30 6.7
sp|Q15648|PPRB_HUMAN Peroxisome proliferator-activated rece... 30 8.8
>sp|Q8IN94|OSA_DROME Trithorax group protein osa (Eyelid protein)
Length = 2716
Score = 140 bits (354), Expect = 4e-33
Identities = 86/272 (31%), Positives = 140/272 (51%), Gaps = 19/272 (6%)
Frame = +2
Query: 11 ESLFFKISESDEEKMMRCISVSNAIRNLSFLGGNDRIIGSNXXXXXXXXXXXXXXHEHST 190
E+ +SES + RCI++SN RNL+F+ GN+ ++ + HEH
Sbjct: 2179 EASLHLVSESQDSLARRCIALSNIFRNLTFVPGNETVLAKSTRFLAVLGRLLLLNHEHLR 2238
Query: 191 DEWPSSNHEKE--------C--------WWLKWIDDIREHVFVTLVNISSYLELSKHHEI 322
+ N+++E C WW ++ IRE++ V + NI+ +LELS++ E+
Sbjct: 2239 RTPKTRNYDREEDTDFSDSCSSLQGEREWWWDYLITIRENMLVAMANIAGHLELSRYDEL 2298
Query: 323 IVRPIITGLLHWLTCNSAAAEDSLPS---HRVLGCRRLALESMMRLCVHEKNIDFILSTT 493
I RP+I GLLHW C SA +D PS + VL +RLALE++ +LCV + N+D +++T
Sbjct: 2299 IARPLIDGLLHWAVCPSAHGQDPFPSCGPNSVLSPQRLALEALCKLCVTDANVDLVIATP 2358
Query: 494 HKGSDLIIQELFNYLAASFCYPDVQVVKEMSLAVMHYLSMGGENGIGCIYLANAQPNIIS 673
+++L L C + QV++E S+ ++HYL+ + L Q IS
Sbjct: 2359 PFSR---LEKLCAVLTRHLCRNEDQVLREFSVNLLHYLAAADSAMARTVAL---QSPCIS 2412
Query: 674 GLISFIEITESQIRHVVDNMGMEALQARPELM 769
L++FIE E V + G+ L+ P+ M
Sbjct: 2413 YLVAFIEQAEQTALGVANQHGINYLRENPDSM 2444
>sp|Q8NFD5|ARI1B_HUMAN AT-rich interactive domain-containing protein 1B (ARID
domain-containing protein 1B) (Osa homolog 2) (hOsa2)
(p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated
factor 250b) (BAF250B)
Length = 2236
Score = 112 bits (280), Expect = 1e-24
Identities = 79/243 (32%), Positives = 119/243 (48%), Gaps = 18/243 (7%)
Frame = +2
Query: 59 RCISVSNAIRNLSFLGGNDRIIGSNXXXXXXXXXXXXXXHEHSTDEWPSSNHEKE----- 223
RCI VSN +R+LSF+ GND + + HEH + +EKE
Sbjct: 1931 RCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDK 1990
Query: 224 ---C----WWLKWIDDIREHVFVTLVNISSYLELSKHHEIIVRPIITGLLHWLTCNSAAA 382
C WW ++ +R++ VTL NIS L+LS + E I PI+ GLLHW+ C SA A
Sbjct: 1991 GVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEA 2050
Query: 383 EDSLPS---HRVLGCRRLALESMMRLCVHEKNIDFILST-THKGSDLIIQELFNYLAASF 550
+D P+ + VL +RL LE++ +L + + N+D IL+T + L Y+
Sbjct: 2051 QDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDR- 2109
Query: 551 CYPDVQVVKEMSLAVMHYLSMGGENGIGCIYLANAQPNIISGLISFIE--ITESQIRHVV 724
V +EMS+A++ L+ G I + Q I LISF+E +T +Q +
Sbjct: 2110 ---KNPVCREMSMALLSNLAQGDALAARAIAV---QKGSIGNLISFLEDGVTMAQYQQSQ 2163
Query: 725 DNM 733
N+
Sbjct: 2164 HNL 2166
>sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing protein 1A (ARID
domain-containing protein 1A) (SWI/SNF-related,
matrix-associated, actin-dependent regulator of chromatin
subfamily F member 1) (SWI-SNF complex protein p270)
(B120) (SWI-like) (Osa homolog 1) (hOSA1) (hELD)
(BRG1-associated factor 250) (BAF250) (BRG1-associated
factor 250a) (BAF250A)
Length = 2285
Score = 105 bits (261), Expect = 2e-22
Identities = 70/227 (30%), Positives = 112/227 (49%), Gaps = 15/227 (6%)
Frame = +2
Query: 59 RCISVSNAIRNLSFLGGNDRIIGSNXXXXXXXXXXXXXXHEHSTDEWPSSNHEKE----- 223
RC+ VSN IR+LSF+ GND + + H+H + +EKE
Sbjct: 1980 RCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQ 2039
Query: 224 ---C----WWLKWIDDIREHVFVTLVNISSYLELSKHHEIIVRPIITGLLHWLTCNSAAA 382
C WW ++ +RE+ VTL NIS L+LS + E I P++ GLLHW C SA A
Sbjct: 2040 GVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEA 2099
Query: 383 ED---SLPSHRVLGCRRLALESMMRLCVHEKNIDFILSTTHKGSDLIIQELFNYLAASFC 553
+D +L + VL +RL LE++ +L + + N+D IL+T +++L++ +
Sbjct: 2100 QDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSR---LEKLYSTMVRFLS 2156
Query: 554 YPDVQVVKEMSLAVMHYLSMGGENGIGCIYLANAQPNIISGLISFIE 694
V +EM++ ++ L+ G I + Q I L+ F+E
Sbjct: 2157 DRKNPVCREMAVVLLANLAQGDSLAARAIAV---QKGSIGNLLGFLE 2200
>sp|O43156|K0406_HUMAN Protein KIAA0406
Length = 1089
Score = 34.7 bits (78), Expect = 0.36
Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Frame = +2
Query: 470 IDFILSTTHKGSDLIIQELFNYLAASFCYPDVQ----VVKEMSLAVMHYLSMGGENGIGC 637
+ F+LS+T ++QELF+ L+A P Q V +E+ LAV+ LS + G
Sbjct: 78 LTFVLSSTCVKEQELLQELFSELSACLYSPSSQKPAAVSEELKLAVIQGLSTLMHSAYGD 137
Query: 638 IYLANAQPNIISGL 679
I L +P+I+ L
Sbjct: 138 IILTFYEPSILPRL 151
>sp|P78025|LON_MYCPN ATP-dependent protease La
Length = 795
Score = 32.0 bits (71), Expect = 2.3
Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 6/118 (5%)
Frame = +2
Query: 206 SNHEKECWWLKWIDDIREHVFVT------LVNISSYLELSKHHEIIVRPIITGLLHWLTC 367
S +++ + + + IRE + +T + NI LE + + E I + I++ L H+
Sbjct: 245 SRQQRDFYLREKLRVIREEIGMTSKKEDEVSNIRKKLEENPYPEHIKKRILSELDHFENS 304
Query: 368 NSAAAEDSLPSHRVLGCRRLALESMMRLCVHEKNIDFILSTTHKGSDLIIQELFNYLA 541
+S++ E +L + L + KN+ IL+ H G D + + + YLA
Sbjct: 305 SSSSQESTLTKTYIDTLMNLPWWQESKDNADVKNLIKILNKNHSGLDKVKERVVEYLA 362
>sp|Q7V697|HEM3_PROMM Porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase)
(HMBS) (Pre-uroporphyrinogen synthase)
Length = 317
Score = 30.8 bits (68), Expect = 5.2
Identities = 32/133 (24%), Positives = 57/133 (42%), Gaps = 3/133 (2%)
Frame = +2
Query: 389 SLPSHRVLGCRRLALESMMRLCVHEKNIDFILSTTHKGSDLIIQELFNYLAASFCYPDVQ 568
+LP +LGC + L V++KN + L T +G+ + L YP +
Sbjct: 88 NLPEGLMLGCVTEREDPADALVVNQKNAEHQLDTLPEGAIVGTSSLRRLAQLRHHYPHL- 146
Query: 569 VVKEMSLAVMHYLSMGGENGIGCIYLANAQPNIISGLISFIEITESQIR-HVVDN--MGM 739
V K++ V+ L C+ LA A + ++ S+I H V +G+
Sbjct: 147 VFKDVRGNVITRLEKLDAGNYDCLILAAAGLTRLGFGDRIHQLIPSEISLHAVGQGALGI 206
Query: 740 EALQARPELMEQV 778
E ++ PE++E +
Sbjct: 207 ECVEGHPEVLEAI 219
>sp|Q91V83|K0406_MOUSE Protein KIAA0406 homolog
Length = 1085
Score = 30.4 bits (67), Expect = 6.7
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Frame = +2
Query: 470 IDFILSTTHKGSDLIIQELFNYLAASFCYPDVQ----VVKEMSLAVMHYLSMGGENGIGC 637
+ F+LS+T ++QELF+ L+A P Q + +E+ LAV+ LS +
Sbjct: 78 LTFVLSSTCVREQELLQELFSELSACLYSPSSQKPAALSEELKLAVIQGLSTLMHSAYRD 137
Query: 638 IYLANAQPNIISGL 679
I L +P+I+ L
Sbjct: 138 IILTFYEPSILPRL 151
>sp|Q15648|PPRB_HUMAN Peroxisome proliferator-activated receptor binding protein (PBP)
(PPAR binding protein) (Thyroid hormone
receptor-associated protein complex 220 kDa component)
(Trap220) (Thyroid receptor interacting protein 2)
(TRIP2) (p53 regulatory protein RB18A) (Vitamin D
receptor-interacting protein complex component DRIP205)
(Activator-recruited cofactor 205 kDa component) (ARC205)
Length = 1581
Score = 30.0 bits (66), Expect = 8.8
Identities = 15/45 (33%), Positives = 24/45 (53%)
Frame = -3
Query: 270 TNTCSLISSIHFNHQHSFS*LEDGHSSVLCSCPSNNKRPKITKII 136
+N+C+ SS + S S ++ H S PS NK+P +T +I
Sbjct: 1263 SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVI 1307
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,347,105
Number of Sequences: 369166
Number of extensions: 1717248
Number of successful extensions: 3682
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3581
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3674
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8694177530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)