Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_011_C08 (480 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P51637|CAV3_MOUSE Caveolin-3 (M-caveolin) 108 6e-24 sp|P51638|CAV3_RAT Caveolin-3 106 3e-23 sp|P56539|CAV3_HUMAN Caveolin-3 (M-caveolin) 105 7e-23 sp|Q9YGM8|CAV1_FUGRU Caveolin-1 102 6e-22 sp|Q6RVA9|CAV1_PIG Caveolin-1 100 2e-21 sp|P33724|CAV1_CANFA Caveolin-1 (Vesicular integral-membran... 100 2e-21 sp|Q03135|CAV1_HUMAN Caveolin-1 99 4e-21 sp|P79132|CAV1_BOVIN Caveolin-1 98 9e-21 sp|P49817|CAV1_MOUSE Caveolin-1 97 2e-20 sp|P35431|CAV1_CHICK Caveolin-1 96 4e-20
>sp|P51637|CAV3_MOUSE Caveolin-3 (M-caveolin) Length = 151 Score = 108 bits (270), Expect = 6e-24 Identities = 51/126 (40%), Positives = 72/126 (57%), Gaps = 1/126 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+NIN I + +ED IAEPEG S D +WK SF F + CYR +S LLG Sbjct: 22 IDLVNRDPKNINEDIVKVDFEDVIAEPEGTYSFDGVWKVSFTTFTVSKYWCYRLLSTLLG 81 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 + + L WG +ACI+ CHIW ++PCIK Y++ + I + C P G Sbjct: 82 VPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCS 141 Query: 372 HFRITM 389 + ++ + Sbjct: 142 NIKVVL 147
>sp|P51638|CAV3_RAT Caveolin-3 Length = 151 Score = 106 bits (264), Expect = 3e-23 Identities = 49/126 (38%), Positives = 72/126 (57%), Gaps = 1/126 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+NIN I + +ED IAEPEG S D +W+ S+ F + CYR +S LLG Sbjct: 22 IDLVNRDPKNINEDIVKVDFEDVIAEPEGTYSFDGVWRVSYTTFTVSKYWCYRLLSTLLG 81 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 + + L WG +ACI+ CHIW ++PCIK Y++ + I + C P G Sbjct: 82 VPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCS 141 Query: 372 HFRITM 389 + ++ + Sbjct: 142 NIKVVL 147
>sp|P56539|CAV3_HUMAN Caveolin-3 (M-caveolin) Length = 151 Score = 105 bits (261), Expect = 7e-23 Identities = 50/128 (39%), Positives = 71/128 (55%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+NIN I + +ED IAEP G S D +WK S+ F + CYR +S LLG Sbjct: 22 IDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLG 81 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 + + L WG +ACI+ CHIW ++PCIK Y++ + I + C P G Sbjct: 82 VPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCS 141 Query: 372 HFRITMDK 395 ++ + K Sbjct: 142 SIKVVLRK 149
>sp|Q9YGM8|CAV1_FUGRU Caveolin-1 Length = 181 Score = 102 bits (253), Expect = 6e-22 Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP ++N + + +ED IAEP G S D +WKASF F + CYR ++ L+G Sbjct: 52 IDLVNRDPTHLNDDVVKVDFEDVIAEPAGTYSFDGVWKASFTTFTVTKYWCYRLLTALVG 111 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 I + L WG +A ++ HIW ++PC+K Y++ + ++ V C P E G C G Sbjct: 112 IPLALIWGIFFAILSFIHIWAVVPCVKSYLIEIHCISRVYSICVHTFCDPLFEAMGKCLG 171 Query: 372 HFRITMDK 395 RI K Sbjct: 172 GVRIRTSK 179
>sp|Q6RVA9|CAV1_PIG Caveolin-1 Length = 178 Score = 100 bits (249), Expect = 2e-21 Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+++N + + +ED IAEPEG S D +WKASF F + YR +S L G Sbjct: 49 IDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFG 108 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 I + L WG +A ++ HIW ++PCIK +++ + ++ V C P E G Sbjct: 109 IPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFS 168 Query: 372 HFRITMDK 395 + RI M K Sbjct: 169 NIRINMQK 176
>sp|P33724|CAV1_CANFA Caveolin-1 (Vesicular integral-membrane protein VIP21) Length = 178 Score = 100 bits (248), Expect = 2e-21 Identities = 49/128 (38%), Positives = 72/128 (56%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+++N + + +ED IAEPEG S D +WKASF F + YR +S L G Sbjct: 49 IDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFG 108 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 I + L WG +A ++ HIW ++PCIK +++ + ++ V C P E G Sbjct: 109 IPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPFFEAVGKIFS 168 Query: 372 HFRITMDK 395 + RI M K Sbjct: 169 NIRINMQK 176
>sp|Q03135|CAV1_HUMAN Caveolin-1 Length = 178 Score = 99.4 bits (246), Expect = 4e-21 Identities = 48/128 (37%), Positives = 72/128 (56%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+++N + + +ED IAEPEG S D +WKASF F + YR +S L G Sbjct: 49 IDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFG 108 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 I + L WG +A ++ HIW ++PCIK +++ + ++ V C P E G Sbjct: 109 IPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFS 168 Query: 372 HFRITMDK 395 + RI + K Sbjct: 169 NVRINLQK 176
>sp|P79132|CAV1_BOVIN Caveolin-1 Length = 178 Score = 98.2 bits (243), Expect = 9e-21 Identities = 48/128 (37%), Positives = 71/128 (55%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+++N + + +ED IAEPEG S D +WKASF F + YR +S L G Sbjct: 49 IDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFG 108 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 I + L WG +A ++ HIW ++PCIK +++ + ++ V C P E G Sbjct: 109 IPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFS 168 Query: 372 HFRITMDK 395 + RI K Sbjct: 169 NIRINTQK 176
>sp|P49817|CAV1_MOUSE Caveolin-1 Length = 178 Score = 97.1 bits (240), Expect = 2e-20 Identities = 47/128 (36%), Positives = 72/128 (56%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+++N + + +ED IAEPEG S D +WKASF F + YR +S + G Sbjct: 49 IDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSTIFG 108 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 I + L WG +A ++ HIW ++PCIK +++ + ++ V C P E G Sbjct: 109 IPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFS 168 Query: 372 HFRITMDK 395 + RI+ K Sbjct: 169 NIRISTQK 176
>sp|P35431|CAV1_CHICK Caveolin-1 Length = 178 Score = 95.9 bits (237), Expect = 4e-20 Identities = 46/128 (35%), Positives = 71/128 (55%), Gaps = 1/128 (0%) Frame = +3 Query: 15 LDLENRDPRNINSHI-EATWEDNIAEPEGVKSCDCLWKASFKCFNGGRDCCYRFISGLLG 191 +DL NRDP+++N + + +ED IAEPEG S D +WKASF F + YR +S + G Sbjct: 49 IDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSAIFG 108 Query: 192 ICIGLYWGCCYACIACCHIWCLIPCIKIYVLHCALLKKIIKAQVDCCCGPCAEICGLCGG 371 I + L WG +A ++ HIW ++PCI+ Y++ + ++ + C P E G Sbjct: 109 IPMALIWGIYFAILSFLHIWAVVPCIRSYLIEIQCISRVYSICIHTFCDPLFEAMGKVFS 168 Query: 372 HFRITMDK 395 R T+ K Sbjct: 169 SIRATVRK 176
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 52,984,749 Number of Sequences: 369166 Number of extensions: 1078387 Number of successful extensions: 3102 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2890 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3063 length of database: 68,354,980 effective HSP length: 102 effective length of database: 49,512,010 effective search space used: 2822184570 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)