Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_011_B16 (847 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein mem... 397 e-110 sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein m... 397 e-110 sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein m... 397 e-110 sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein m... 397 e-110 sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein m... 295 8e-80 sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 ... 229 7e-60 sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein m... 177 3e-44 sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein m... 176 6e-44 sp|Q5R8F1|TM9S1_PONPY Transmembrane 9 superfamily protein m... 176 6e-44 sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein m... 175 2e-43
>sp|Q66HG5|TM9S2_RAT Transmembrane 9 superfamily protein member 2 precursor Length = 663 Score = 397 bits (1019), Expect = e-110 Identities = 181/264 (68%), Positives = 222/264 (84%), Gaps = 1/264 (0%) Frame = +2 Query: 2 LKTMPQSNIQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLD-TEEAQEEFGWKL 178 L++MP ++IQWFSI+NS++IVLFLSGM+AMI+L+TLH+DI RYN++D TE+AQEEFGWKL Sbjct: 291 LESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQEEFGWKL 350 Query: 179 VHGDVFRPPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVLF 358 VHGD+FRPPR GM L VF+GSG Q+++MT VTLF +C GFLSPANRGA TC +V +VL Sbjct: 351 VHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLL 410 Query: 359 GAFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTTI 538 G AG+ +AR YK GEKWK+NVLLT+FLCPG VF FF++N++LW GSSAA+PF T+ Sbjct: 411 GTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTL 470 Query: 539 LGLLAMWFLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVL 718 + +LA+WF ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+L Sbjct: 471 VAILALWFCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGIL 530 Query: 719 PFGCIFIQLFFILNSIWSTYVYYM 790 PFGCIFIQLFFILNSIWS +YYM Sbjct: 531 PFGCIFIQLFFILNSIWSHQMYYM 554
>sp|Q99805|TM9S2_HUMAN Transmembrane 9 superfamily protein member 2 precursor (p76) Length = 663 Score = 397 bits (1019), Expect = e-110 Identities = 181/264 (68%), Positives = 222/264 (84%), Gaps = 1/264 (0%) Frame = +2 Query: 2 LKTMPQSNIQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLD-TEEAQEEFGWKL 178 L++MP ++IQWFSI+NS++IVLFLSGM+AMI+L+TLH+DI RYN++D TE+AQEEFGWKL Sbjct: 291 LESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQEEFGWKL 350 Query: 179 VHGDVFRPPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVLF 358 VHGD+FRPPR GM L VF+GSG Q+++MT VTLF +C GFLSPANRGA TC +V +VL Sbjct: 351 VHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLL 410 Query: 359 GAFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTTI 538 G AG+ +AR YK GEKWK+NVLLT+FLCPG VF FF++N++LW GSSAA+PF T+ Sbjct: 411 GTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTL 470 Query: 539 LGLLAMWFLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVL 718 + +LA+WF ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+L Sbjct: 471 VAILALWFCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGIL 530 Query: 719 PFGCIFIQLFFILNSIWSTYVYYM 790 PFGCIFIQLFFILNSIWS +YYM Sbjct: 531 PFGCIFIQLFFILNSIWSHQMYYM 554
>sp|P58021|TM9S2_MOUSE Transmembrane 9 superfamily protein member 2 precursor Length = 662 Score = 397 bits (1019), Expect = e-110 Identities = 181/264 (68%), Positives = 222/264 (84%), Gaps = 1/264 (0%) Frame = +2 Query: 2 LKTMPQSNIQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLD-TEEAQEEFGWKL 178 L++MP ++IQWFSI+NS++IVLFLSGM+AMI+L+TLH+DI RYN++D TE+AQEEFGWKL Sbjct: 290 LESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQEEFGWKL 349 Query: 179 VHGDVFRPPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVLF 358 VHGD+FRPPR GM L VF+GSG Q+++MT VTLF +C GFLSPANRGA TC +V +VL Sbjct: 350 VHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLL 409 Query: 359 GAFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTTI 538 G AG+ +AR YK GEKWK+NVLLT+FLCPG VF FF++N++LW GSSAA+PF T+ Sbjct: 410 GTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTL 469 Query: 539 LGLLAMWFLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVL 718 + +LA+WF ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+L Sbjct: 470 VAILALWFCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGIL 529 Query: 719 PFGCIFIQLFFILNSIWSTYVYYM 790 PFGCIFIQLFFILNSIWS +YYM Sbjct: 530 PFGCIFIQLFFILNSIWSHQMYYM 553
>sp|Q5R8Y6|TM9S2_PONPY Transmembrane 9 superfamily protein member 2 precursor Length = 663 Score = 397 bits (1019), Expect = e-110 Identities = 181/264 (68%), Positives = 222/264 (84%), Gaps = 1/264 (0%) Frame = +2 Query: 2 LKTMPQSNIQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLD-TEEAQEEFGWKL 178 L++MP ++IQWFSI+NS++IVLFLSGM+AMI+L+TLH+DI RYN++D TE+AQEEFGWKL Sbjct: 291 LESMPHTHIQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQEEFGWKL 350 Query: 179 VHGDVFRPPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVLF 358 VHGD+FRPPR GM L VF+GSG Q+++MT VTLF +C GFLSPANRGA TC +V +VL Sbjct: 351 VHGDIFRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLL 410 Query: 359 GAFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTTI 538 G AG+ +AR YK GEKWK+NVLLT+FLCPG VF FF++N++LW GSSAA+PF T+ Sbjct: 411 GTPAGYVAARFYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTL 470 Query: 539 LGLLAMWFLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVL 718 + +LA+WF ISVPL F+GAYFGFKK I PVRTNQIPRQIP Q YT+ +P I+MGG+L Sbjct: 471 VAILALWFCISVPLTFIGAYFGFKKNAIEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGIL 530 Query: 719 PFGCIFIQLFFILNSIWSTYVYYM 790 PFGCIFIQLFFILNSIWS +YYM Sbjct: 531 PFGCIFIQLFFILNSIWSHQMYYM 554
>sp|Q92544|TM9S4_HUMAN Transmembrane 9 superfamily protein member 4 Length = 625 Score = 295 bits (756), Expect = 8e-80 Identities = 139/262 (53%), Positives = 178/262 (67%), Gaps = 1/262 (0%) Frame = +2 Query: 8 TMPQSNIQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLDT-EEAQEEFGWKLVH 184 TM I WFSI+NSV++V FLSG+L+MI+++TL +DI YNK D E+ EE GWKLVH Sbjct: 255 TMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVH 314 Query: 185 GDVFRPPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVLFGA 364 GDVFRPP+ M L +GSG+QL M ++ +F++ G LSP++RGA T ++ G Sbjct: 315 GDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGV 374 Query: 365 FAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTTILG 544 F GF + RLY+ + G +WK TA L PG VFGI FVLN +W SS AVPF T++ Sbjct: 375 FGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVA 434 Query: 545 LLAMWFLISVPLCFVGAYFGFKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGVLPF 724 LL MWF IS+PL ++G YFGF+KQP PVRTNQIPRQIP Q Y ILM G+LPF Sbjct: 435 LLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPF 494 Query: 725 GCIFIQLFFILNSIWSTYVYYM 790 G +FI+LFFI ++IW YY+ Sbjct: 495 GAMFIELFFIFSAIWENQFYYL 516
>sp|P32802|EMP70_YEAST Endosomal P24A protein precursor (70 kDa endomembrane protein) (Pheromone alpha-factor transporter) (Acidic 24 kDa late endocytic intermediate component) Length = 667 Score = 229 bits (584), Expect = 7e-60 Identities = 110/258 (42%), Positives = 164/258 (63%), Gaps = 2/258 (0%) Frame = +2 Query: 23 NIQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLDTEEA-QEEFGWKLVHGDVFR 199 +IQWFS++N ++V+ LS ++ LL+ L D RYN+L+ ++ QE+ GWKL HGDVFR Sbjct: 302 SIQWFSLINFSLVVVLLSSVVIHSLLRALKSDFARYNELNLDDDFQEDSGWKLNHGDVFR 361 Query: 200 PPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVLFGAFAGFY 379 P +TL + VGSGVQL LM ++F + GFLSP++RG+ AT + Y LFG + Sbjct: 362 SPSQSLTLSILVGSGVQLFLMVTCSIFFAALGFLSPSSRGSLATVMFILYALFGFVGSYT 421 Query: 380 SARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTTILGLLAMW 559 S +YK +G WK+N++LT L PG++ I LN L SS +P +T+ ++ +W Sbjct: 422 SMGIYKFFNGPYWKANLILTPLLVPGAILLIIIALNFFLMFVHSSGVIPASTLFFMVFLW 481 Query: 560 FLISVPLCFVGAYFGFKKQPISQ-PVRTNQIPRQIPYQYLYTRSIPSILMGGVLPFGCIF 736 FL S+PL F G+ K+ + P +TNQI RQIP+Q Y ++IP+ L+ G+ PFG I Sbjct: 482 FLFSIPLSFAGSLIARKRCHWDEHPTKTNQIARQIPFQPWYLKTIPATLIAGIFPFGSIA 541 Query: 737 IQLFFILNSIWSTYVYYM 790 ++L+FI S+W ++YM Sbjct: 542 VELYFIYTSLWFNKIFYM 559
>sp|Q9DBU0|TM9S1_MOUSE Transmembrane 9 superfamily protein member 1 precursor Length = 606 Score = 177 bits (449), Expect = 3e-44 Identities = 96/264 (36%), Positives = 147/264 (55%), Gaps = 11/264 (4%) Frame = +2 Query: 26 IQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLDTEEA---------QEEFGWKL 178 I W SI+NS+++V L G +A+IL++ L D+ RYN LD E + Q + GWK+ Sbjct: 234 IHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYN-LDEETSSGGSSDDFDQGDNGWKI 292 Query: 179 VHGDVFR-PPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVL 355 +H DVFR PP G+ LC +G G Q + + + ++ G + GA + I+ Y L Sbjct: 293 IHTDVFRFPPYRGL-LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYAL 351 Query: 356 FGAFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTT 535 +G+ S+ Y+ + GE+W N++LT+ L F + V+N V WA+GS+ A+P TT Sbjct: 352 TCCISGYVSSHFYRQIGGERWVWNIILTSSLFSVPFFLTWSVVNSVHWANGSTQALPATT 411 Query: 536 ILGLLAMWFLISVPLCFVGAYFGFKK-QPISQPVRTNQIPRQIPYQYLYTRSIPSILMGG 712 IL LL +W L+ PL +G FG P P RT I R+IP Q Y ++ + +GG Sbjct: 412 ILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGG 471 Query: 713 VLPFGCIFIQLFFILNSIWSTYVY 784 LPF I ++L++I ++W Y Sbjct: 472 FLPFSAISVELYYIFATVWGREQY 495
>sp|O15321|TM9S1_HUMAN Transmembrane 9 superfamily protein member 1 precursor (hMP70) Length = 606 Score = 176 bits (447), Expect = 6e-44 Identities = 96/264 (36%), Positives = 145/264 (54%), Gaps = 11/264 (4%) Frame = +2 Query: 26 IQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLDTEEA---------QEEFGWKL 178 I W SI+NS+++V L G +A+IL++ L D+ RYN LD E Q + GWK+ Sbjct: 234 IHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYN-LDEETTSAGSGDDFDQGDNGWKI 292 Query: 179 VHGDVFR-PPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVL 355 +H DVFR PP G+ LC +G G Q + + + ++ G + GA + I+ Y L Sbjct: 293 IHTDVFRFPPYRGL-LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYAL 351 Query: 356 FGAFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTT 535 +G+ S+ Y+ + GE+W N++LT L F + V+N V WA+GS+ A+P TT Sbjct: 352 TCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATT 411 Query: 536 ILGLLAMWFLISVPLCFVGAYFGFKK-QPISQPVRTNQIPRQIPYQYLYTRSIPSILMGG 712 IL LL +W L+ PL +G FG P P RT I R+IP Q Y ++ + +GG Sbjct: 412 ILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGG 471 Query: 713 VLPFGCIFIQLFFILNSIWSTYVY 784 LPF I ++L++I ++W Y Sbjct: 472 FLPFSAISVELYYIFATVWGREQY 495
>sp|Q5R8F1|TM9S1_PONPY Transmembrane 9 superfamily protein member 1 precursor Length = 606 Score = 176 bits (447), Expect = 6e-44 Identities = 96/264 (36%), Positives = 145/264 (54%), Gaps = 11/264 (4%) Frame = +2 Query: 26 IQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLDTEEA---------QEEFGWKL 178 I W SI+NS+++V L G +A+IL++ L D+ RYN LD E Q + GWK+ Sbjct: 234 IHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYN-LDEETTSAGSGDDFDQGDNGWKI 292 Query: 179 VHGDVFR-PPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVL 355 +H DVFR PP G+ LC +G G Q + + + ++ G + GA + I+ Y L Sbjct: 293 IHTDVFRFPPYRGL-LCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYAL 351 Query: 356 FGAFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTT 535 +G+ S+ Y+ + GE+W N++LT L F + V+N V WA+GS+ A+P TT Sbjct: 352 TCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATT 411 Query: 536 ILGLLAMWFLISVPLCFVGAYFGFKK-QPISQPVRTNQIPRQIPYQYLYTRSIPSILMGG 712 IL LL +W L+ PL +G FG P P RT I R+IP Q Y ++ + +GG Sbjct: 412 ILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGG 471 Query: 713 VLPFGCIFIQLFFILNSIWSTYVY 784 LPF I ++L++I ++W Y Sbjct: 472 FLPFSAISVELYYIFATVWGREQY 495
>sp|Q9ET30|TM9S3_MOUSE Transmembrane 9 superfamily protein member 3 precursor Length = 587 Score = 175 bits (443), Expect = 2e-43 Identities = 90/265 (33%), Positives = 144/265 (54%), Gaps = 7/265 (2%) Frame = +2 Query: 17 QSNIQWFSILNSVIIVLFLSGMLAMILLKTLHRDIDRYNKLDT-----EEAQEEFGWKLV 181 Q I WFSI NS ++V+FL G+++MIL++TL +D RY+K + + +E+GWK V Sbjct: 216 QHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQV 275 Query: 182 HGDVFRPPRMGMTLCVFVGSGVQLILMTIVTLFISCFGFLSPANRGAFATCGIVFYVLFG 361 HGDVFRP + +GSG Q+ ++++ + ++ L RG+ + I Y Sbjct: 276 HGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLY-TERGSMLSTAIFVYAATS 334 Query: 362 AFAGFYSARLYKMMSGEKWKSNVLLTAFLCPGSVFGIFFVLNIVLWASGSSAAVPFTTIL 541 G++ LY G +W + + AFL P V G F +N + +S A+PF T++ Sbjct: 335 PVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMV 394 Query: 542 GLLAMWFLISVPLCFVGAYFG--FKKQPISQPVRTNQIPRQIPYQYLYTRSIPSILMGGV 715 + + F + +PL VG G QP + P R N +PR IP + + + +GG+ Sbjct: 395 AVCCICFFVILPLNLVGTILGRNLSGQP-NFPCRVNAVPRPIPEKKWFMEPAVIVCLGGI 453 Query: 716 LPFGCIFIQLFFILNSIWSTYVYYM 790 LPFG IFI+++FI S W+ +YY+ Sbjct: 454 LPFGSIFIEMYFIFTSFWAYKIYYV 478
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 104,619,547 Number of Sequences: 369166 Number of extensions: 2261014 Number of successful extensions: 6516 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6172 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6488 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8293644780 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)