Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_A20
(825 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H477|RBSK_HUMAN Ribokinase 162 1e-39
sp|P44331|RBSK_HAEIN Ribokinase 124 3e-28
sp|O60116|RBSK_SCHPO Putative ribokinase 115 1e-25
sp|P0A9J6|RBSK_ECOLI Ribokinase >gi|71152935|sp|P0A9J7|RBSK... 95 2e-19
sp|Q9K6K1|RBSK_BACHD Ribokinase 94 6e-19
sp|Q9CF42|RBSK_LACLA Ribokinase 88 3e-17
sp|P36945|RBSK_BACSU Ribokinase 81 4e-15
sp|P25332|RBSK_YEAST Probable ribokinase 72 2e-12
sp|P32143|YIHV_ECOLI Hypothetical sugar kinase yihV 71 3e-12
sp|P37829|SCRK_SOLTU Fructokinase 60 7e-09
>sp|Q9H477|RBSK_HUMAN Ribokinase
Length = 322
Score = 162 bits (410), Expect = 1e-39
Identities = 98/263 (37%), Positives = 152/263 (57%), Gaps = 1/263 (0%)
Frame = +2
Query: 2 NSVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDK 181
N VQA RLG ++ ++ K+G D +G + +ENL+ ++T+ + A + A + V+
Sbjct: 57 NQCVQAARLGAMT-SMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNN 115
Query: 182 SGSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHVKTI 361
G N IV+ +GA+ LL+ D+ +I+ +KV++ EI LEAL++A+R VKT+
Sbjct: 116 EGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTL 175
Query: 362 LVPAPVPKDFTANMIPDVDIICPNEIEAGQMLGMKIDSIEAAKEAIEKFYETRNVKWPII 541
PAP D D+ C NE EA + G+ + S A EA + R + II
Sbjct: 176 FNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLK-RGCQVVII 234
Query: 542 TMGAKGAVV-GIKPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQLFKNPSQSIDSMVSRS 718
T+GA+G VV +H+ KV++VDTTGAGDSFVG+LA+ L P+ S++ M++RS
Sbjct: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
Query: 719 IFVASMSTLKEGTRTSYVSAKDL 787
F+A++S GT++SY KDL
Sbjct: 295 NFIAAVSVQAAGTQSSYPYKKDL 317
>sp|P44331|RBSK_HAEIN Ribokinase
Length = 306
Score = 124 bits (311), Expect = 3e-28
Identities = 86/255 (33%), Positives = 134/255 (52%)
Frame = +2
Query: 2 NSVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDK 181
N V A RLG V I IG+D G G++T H+ + + +AF+ V K
Sbjct: 44 NQAVAAARLG-AKVAFISCIGSDSIGKTMKNAFAQEGIDTTHINTVSQEMTGMAFIQVAK 102
Query: 182 SGSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHVKTI 361
S N IVLASGA+ LS + + IA S L+ E P+ A IAK+ VK +
Sbjct: 103 SSENSIVLASGANSHLSEMVVRQSEAQIAQSDCLLMQLETPLSGVELAAQIAKKNGVKVV 162
Query: 362 LVPAPVPKDFTANMIPDVDIICPNEIEAGQMLGMKIDSIEAAKEAIEKFYETRNVKWPII 541
L PAP + + ++ +DII PNE EA + G+++ ++A +A F++ + ++ +I
Sbjct: 163 LNPAPA-QILSDELLSLIDIITPNETEAEILTGVEVADEQSAVKAASVFHD-KGIETVMI 220
Query: 542 TMGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQLFKNPSQSIDSMVSRSI 721
T+GAKG V K G SR ++ V+++DTT AGD+F G L + +S D +
Sbjct: 221 TLGAKGVFVSRK-GKSRIIKGFCVQAIDTTAAGDTFNGGFVTALLE--EKSFDEAIRFGQ 277
Query: 722 FVASMSTLKEGTRTS 766
A++S K+G ++S
Sbjct: 278 AAAAISVTKKGAQSS 292
>sp|O60116|RBSK_SCHPO Putative ribokinase
Length = 318
Score = 115 bits (289), Expect = 1e-25
Identities = 77/230 (33%), Positives = 125/230 (54%), Gaps = 9/230 (3%)
Frame = +2
Query: 2 NSVVQAIRLG---DVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVT 172
N V RL D V ++G +G+D +G+E L L+ GVN D+VK + VA +
Sbjct: 45 NQAVAVARLSNPADTKVSMLGCVGDDAFGVEMLSGLKKDGVNVDNVKKIENKSTGVAMII 104
Query: 173 VDKSGSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHV 352
V+++G N I+L+ GA+ + + + + I+T +LI EIP++A AL IA + V
Sbjct: 105 VEETGENRILLSEGANGNVDTAFVKAMEQRISTCNLLIMQLEIPLEAVEIALQIAHKHGV 164
Query: 353 KTILVPAP-VPKDFTANMIPDVDIICPNEIEAGQMLGM-----KIDSIEAAKEAIEKFYE 514
++ PAP +P + +MI + PNE EA +L +++++A + F
Sbjct: 165 DVLMNPAPAIP--LSHDMISYCAYLVPNEHEAAILLNQADSPATLENVDAYASKLLSFGV 222
Query: 515 TRNVKWPIITMGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSLA 664
+ V IIT+G++GA G S V A KV++VDTT AGD+F+G+ +
Sbjct: 223 RKAV---IITLGSQGAYYKSANGESALVSACKVKAVDTTAAGDTFIGAFS 269
>sp|P0A9J6|RBSK_ECOLI Ribokinase
sp|P0A9J7|RBSK_ECO57 Ribokinase
Length = 309
Score = 95.1 bits (235), Expect = 2e-19
Identities = 68/255 (26%), Positives = 130/255 (50%)
Frame = +2
Query: 2 NSVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDK 181
N V A R G ++ I G+D G + L + ++ V + + VA + V+
Sbjct: 46 NQAVAAGRSG-ANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNG 104
Query: 182 SGSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHVKTI 361
G N I + +GA+ LS + + E IA + L+ E P+++ + A IA +
Sbjct: 105 EGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVA 164
Query: 362 LVPAPVPKDFTANMIPDVDIICPNEIEAGQMLGMKIDSIEAAKEAIEKFYETRNVKWPII 541
L PAP ++ ++ VDII PNE EA ++ G+++++ E A +A + +E + ++ +I
Sbjct: 165 LNPAPA-RELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHE-KGIRTVLI 222
Query: 542 TMGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQLFKNPSQSIDSMVSRSI 721
T+G++G + G + V +V++VDT AGD+F G+L L + + + + +
Sbjct: 223 TLGSRGVWASVN-GEGQRVPGFRVQAVDTIAAGDTFNGALITALLE--EKPLPEAIRFAH 279
Query: 722 FVASMSTLKEGTRTS 766
A+++ ++G + S
Sbjct: 280 AAAAIAVTRKGAQPS 294
>sp|Q9K6K1|RBSK_BACHD Ribokinase
Length = 294
Score = 93.6 bits (231), Expect = 6e-19
Identities = 75/224 (33%), Positives = 108/224 (48%)
Frame = +2
Query: 2 NSVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDK 181
N V A RLG +V +IG++G+D +G ENL G+ TD VK S VA + +
Sbjct: 45 NQAVAAARLG-ANVRMIGRVGDDPFGHVLTENLAKEGIITDSVKPVTDCTSGVATILLSD 103
Query: 182 SGSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHVKTI 361
N I++ GA++ ++ + + +A S V++ EIP++ L + HV T+
Sbjct: 104 R-DNRIIVTKGANEHVTPDYVAAFEQELAASDVVLLQLEIPLETVAYVLEFCAKHHVTTV 162
Query: 362 LVPAPVPKDFTANMIPDVDIICPNEIEAGQMLGMKIDSIEAAKEAIEKFYETRNVKWPII 541
L PAP K A D I PNE E Q+ G + D+ K I+
Sbjct: 163 LNPAPAQKLPDAAW-TDATYISPNENECLQLFGDEPDANLRQK--------------LIM 207
Query: 542 TMGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQL 673
T GA G V + VE+ +VE VDTTGAGD+F G+ A L
Sbjct: 208 TKGADG-VQFYENDEQVQVESFRVEPVDTTGAGDTFNGAFAVAL 250
>sp|Q9CF42|RBSK_LACLA Ribokinase
Length = 300
Score = 87.8 bits (216), Expect = 3e-17
Identities = 75/253 (29%), Positives = 119/253 (47%)
Frame = +2
Query: 2 NSVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDK 181
N V RL V +IG +G D +G L+N + V ++V + + +A +T+
Sbjct: 43 NQAVAFARLSPNEVSMIGAVGKDAFGESILQNFKENAVLFENVGTVPQT-TGIAQITL-Y 100
Query: 182 SGSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHVKTI 361
N I++ GA+ + S + + E I S+++I EIP + L K +K +
Sbjct: 101 DDDNRIIIIPGANNEVLPSYLADLWEKIKESQLVILQNEIPHETNLAIAKFCKENAIKVL 160
Query: 362 LVPAPVPKDFTANMIPDVDIICPNEIEAGQMLGMKIDSIEAAKEAIEKFYETRNVKWPII 541
PAP K MI VD I PNE E ++ A E I K Y R I+
Sbjct: 161 YNPAPARKT-DLEMIDFVDYITPNEHECKELFP------NLALEEILKKYSNRL----IV 209
Query: 542 TMGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQLFKNPSQSIDSMVSRSI 721
T+G++G + L + + A K + VDTTGAGD+F G+ A+ L +N SI + ++
Sbjct: 210 TLGSEGVIFHDGETLQK-IPAIKAKVVDTTGAGDTFNGAFAFGLTEN--LSISDSIRLAV 266
Query: 722 FVASMSTLKEGTR 760
+ +S K G +
Sbjct: 267 VASHLSIQKFGAQ 279
>sp|P36945|RBSK_BACSU Ribokinase
Length = 293
Score = 80.9 bits (198), Expect = 4e-15
Identities = 72/263 (27%), Positives = 119/263 (45%)
Frame = +2
Query: 2 NSVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDK 181
N V A RLG V ++GK+G+D YG L NL++ GV TD+++ +S A + +
Sbjct: 43 NQAVAAARLG-AQVFMVGKVGDDHYGTAILNNLKANGVRTDYMEPVTHTESGTAHIVL-A 100
Query: 182 SGSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHVKTI 361
G N IV+ GA+ ++ + + E I +++ EIP + E + I
Sbjct: 101 EGDNSIVVVKGANDDITPAYALNALEQIEKVDMVLIQQEIPEETVDEVCKYCHSHDIPII 160
Query: 362 LVPAPVPKDFTANMIPDVDIICPNEIEAGQMLGMKIDSIEAAKEAIEKFYETRNVKWPII 541
L PAP + I + PNE EA +L ++ EA K + T +
Sbjct: 161 LNPAPA-RPLKQETIDHATYLTPNEHEA-SILFPELTISEALALYPAKLFITEGKQGVRY 218
Query: 542 TMGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQLFKNPSQSIDSMVSRSI 721
+ G+K ++ P VE VDTTGAGD+F + A L + + I++ + +
Sbjct: 219 SAGSKEVLIPSFP----------VEPVDTTGAGDTFNAAFAVALAE--GKDIEAALRFAN 266
Query: 722 FVASMSTLKEGTRTSYVSAKDLE 790
AS+S G + + ++E
Sbjct: 267 RAASLSVCSFGAQGGMPTRNEVE 289
>sp|P25332|RBSK_YEAST Probable ribokinase
Length = 333
Score = 72.0 bits (175), Expect = 2e-12
Identities = 69/280 (24%), Positives = 125/280 (44%), Gaps = 29/280 (10%)
Frame = +2
Query: 38 SVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDKS--GSNHIVLAS 211
SV +IG +GND +G + + L GV+ HV + A + +++ G N I++
Sbjct: 58 SVRMIGNVGNDTFGKQLKDTLSDCGVDITHVGTYEGINTGTATILIEEKAGGQNRILIVE 117
Query: 212 GADQLLSVSDIVECTELIATSK----VLISNFEIPMDACLEALSIAKRFHVKTILVPAPV 379
GA+ ++ D + E+ K ++ EIP + A R + + + P+P
Sbjct: 118 GANSK-TIYDPKQLCEIFPEGKEEEEYVVFQHEIPDPLSIIKWIHANRPNFQIVYNPSP- 175
Query: 380 PKDFTANMIPD---VDIICPNEIEAGQMLGMKIDS--IEAAKEAI--------------- 499
F A D VD++ NEIE Q++ D+ +E +E I
Sbjct: 176 ---FKAMPKKDWELVDLLVVNEIEGLQIVESVFDNELVEEIREKIKDDFLGEYRKICELL 232
Query: 500 -EKFYETRNVKWPIITMGAKGAVVGI--KPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQ 670
EK + ++T+G++G + P + V VDTTGAGD+F+G L Q
Sbjct: 233 YEKLMNRKKRGIVVMTLGSRGVLFCSHESPEVQFLPAIQNVSVVDTTGAGDTFLGGLVTQ 292
Query: 671 LFKNPSQSIDSMVSRSIFVASMSTLKEGTRTSYVSAKDLE 790
L++ +++ + + S +S++ ++G S KD++
Sbjct: 293 LYQ--GETLSTAIKFSTLASSLTIQRKGAAESMPLYKDVQ 330
>sp|P32143|YIHV_ECOLI Hypothetical sugar kinase yihV
Length = 298
Score = 71.2 bits (173), Expect = 3e-12
Identities = 68/223 (30%), Positives = 109/223 (48%)
Frame = +2
Query: 5 SVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDKS 184
+ V A RLG V IG++G+D G L L S+GVNT + K ++AKSS + + VD
Sbjct: 44 AAVAAARLG-AQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDTK 102
Query: 185 GSNHIVLASGADQLLSVSDIVECTELIATSKVLISNFEIPMDACLEALSIAKRFHVKTIL 364
G I+ D L + E + V++++ D +A ++A++ V T+L
Sbjct: 103 GERIIINYPSPDLLPDAEWLEEID--FSQWDVVLADVRW-HDGAKKAFTLARQAGVMTVL 159
Query: 365 VPAPVPKDFTANMIPDVDIICPNEIEAGQMLGMKIDSIEAAKEAIEKFYETRNVKWPIIT 544
P+D + ++ D +E ++ G+K + A K+A +T +T
Sbjct: 160 DGDITPQDI-SELVALSDHAAFSEPGLARLTGVK-EMASALKQA-----QTLTNGHVYVT 212
Query: 545 MGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSLAYQL 673
G+ G ++ G +H A KV+ VDTTGAGD F G+LA L
Sbjct: 213 QGSAGC-DWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVAL 254
>sp|P37829|SCRK_SOLTU Fructokinase
Length = 319
Score = 60.1 bits (144), Expect = 7e-09
Identities = 64/234 (27%), Positives = 108/234 (46%), Gaps = 14/234 (5%)
Frame = +2
Query: 2 NSVVQAIRLGDVSVGVIGKIGNDIYGMEQLENLRSYGVNTDHVKISHKAKSSVAFVTVDK 181
N + RLG S +GK+G+D +G L++ GV D + A++++AFVT+
Sbjct: 48 NVAIAVTRLGGKSA-FVGKLGDDEFGHMLAGILKTNGVQADGINFDKGARTALAFVTLRA 106
Query: 182 SGSNHIVL--ASGADQLLSVSDIVECTELIATSKVL-ISNFEIPMDACLEALSIAKRFHV 352
G + AD LL+ ++ +LI ++KV + + ++ C A H+
Sbjct: 107 DGEREFMFYRNPSADMLLTPDEL--NLDLIRSAKVFHYGSISLIVEPCRSA-------HL 157
Query: 353 KTILVPAPVPKDFTANMIPDVDIICPN-EIEAGQMLGMKIDSIEAA----------KEAI 499
K + V K+ A + D ++ P EA +K+ +E + A+
Sbjct: 158 KAM----EVAKEAGALLSYDPNLRLPLWSSEAEARKAIKVSDVELEFLTGSDKIDDESAM 213
Query: 500 EKFYETRNVKWPIITMGAKGAVVGIKPGLSRHVEAPKVESVDTTGAGDSFVGSL 661
++ N+K ++T+G KG K V V++VDTTGAGDSFVG+L
Sbjct: 214 SLWHP--NLKLLLVTLGEKGCNYYTKK-FHGSVGGFHVKTVDTTGAGDSFVGAL 264
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,360,817
Number of Sequences: 369166
Number of extensions: 1861986
Number of successful extensions: 5136
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4919
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5109
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7956112725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)