Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_A08
(848 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BUL8|PDC10_HUMAN Programmed cell death protein 10 (TF-... 114 3e-25
sp|Q6DF07|PDC10_XENTR Programmed cell death protein 10 114 3e-25
sp|Q8AVR4|PDC10_XENLA Programmed cell death protein 10 114 3e-25
sp|Q8VE70|PDC10_MOUSE Programmed cell death protein 10 (TF-... 114 4e-25
sp|Q6NX65|PDC10_RAT Programmed cell death protein 10 114 4e-25
sp|Q6PHH3|PDC10_BRARE Programmed cell death protein 10 113 6e-25
sp|Q5ZIV5|PDC10_CHICK Programmed cell death protein 10 112 1e-24
sp|P35875|PARP_DROME Poly [ADP-ribose] polymerase (PARP) (A... 36 0.15
sp|O42649|SMC3_SCHPO Structural maintenance of chromosome 3... 35 0.26
sp|P29461|PTP2_YEAST Tyrosine-protein phosphatase 2 (Protei... 33 0.76
>sp|Q9BUL8|PDC10_HUMAN Programmed cell death protein 10 (TF-1 cell apoptosis-related
protein 15) (Cerebral cavernous malformations 3 protein)
Length = 212
Score = 114 bits (285), Expect = 3e-25
Identities = 63/133 (47%), Positives = 88/133 (66%)
Frame = +2
Query: 125 EVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIK 304
EV+ +E+ LRMA+ + + + L KA LK++LS+IPDEI+DR FL TIK
Sbjct: 73 EVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIK 132
Query: 305 EIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVY 484
+IASAIK LLD V+ V ++ +LE K++FVKYSK FS+TLK +F+D K V+
Sbjct: 133 DIASAIKELLDTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVF 191
Query: 485 ASANLLVNQTNMI 523
SAN L++QTN+I
Sbjct: 192 VSANRLIHQTNLI 204
>sp|Q6DF07|PDC10_XENTR Programmed cell death protein 10
Length = 212
Score = 114 bits (285), Expect = 3e-25
Identities = 63/133 (47%), Positives = 88/133 (66%)
Frame = +2
Query: 125 EVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIK 304
EV+ +E+ LRMA+ + + + L KA LK++LS+IPDEI+DR FL TIK
Sbjct: 73 EVNFTESLLRMAADDVEEYMVERPEPEFQELNEKARALKQILSKIPDEINDRVRFLQTIK 132
Query: 305 EIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVY 484
+IASAIK LLD V+ V ++ +LE K++FVKYSK FS+TLK +F+D K V+
Sbjct: 133 DIASAIKELLDTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKALNVF 191
Query: 485 ASANLLVNQTNMI 523
SAN L++QTN+I
Sbjct: 192 ISANRLIHQTNLI 204
>sp|Q8AVR4|PDC10_XENLA Programmed cell death protein 10
Length = 212
Score = 114 bits (285), Expect = 3e-25
Identities = 63/133 (47%), Positives = 88/133 (66%)
Frame = +2
Query: 125 EVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIK 304
EV+ +E+ LRMA+ + + + L KA LK++LS+IPDEI+DR FL TIK
Sbjct: 73 EVNFTESLLRMAADDVEEYMVERPEPEFQELNEKARALKQILSKIPDEINDRVRFLQTIK 132
Query: 305 EIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVY 484
+IASAIK LLD V+ V ++ +LE K++FVKYSK FS+TLK +F+D K V+
Sbjct: 133 DIASAIKELLDTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKALNVF 191
Query: 485 ASANLLVNQTNMI 523
SAN L++QTN+I
Sbjct: 192 ISANRLIHQTNLI 204
>sp|Q8VE70|PDC10_MOUSE Programmed cell death protein 10 (TF-1 cell apoptosis-related
protein 15)
Length = 212
Score = 114 bits (284), Expect = 4e-25
Identities = 63/133 (47%), Positives = 88/133 (66%)
Frame = +2
Query: 125 EVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIK 304
EV+ +E+ LRMA+ + + + L KA LK++LS+IPDEI+DR FL TIK
Sbjct: 73 EVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIK 132
Query: 305 EIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVY 484
+IASAIK LLD V+ V ++ +LE K++FVKYSK FS+TLK +F+D K V+
Sbjct: 133 DIASAIKELLDTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVF 191
Query: 485 ASANLLVNQTNMI 523
SAN L++QTN+I
Sbjct: 192 ISANRLIHQTNLI 204
>sp|Q6NX65|PDC10_RAT Programmed cell death protein 10
Length = 210
Score = 114 bits (284), Expect = 4e-25
Identities = 63/133 (47%), Positives = 88/133 (66%)
Frame = +2
Query: 125 EVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIK 304
EV+ +E+ LRMA+ + + + L KA LK++LS+IPDEI+DR FL TIK
Sbjct: 71 EVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIK 130
Query: 305 EIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVY 484
+IASAIK LLD V+ V ++ +LE K++FVKYSK FS+TLK +F+D K V+
Sbjct: 131 DIASAIKELLDTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVF 189
Query: 485 ASANLLVNQTNMI 523
SAN L++QTN+I
Sbjct: 190 ISANRLIHQTNLI 202
>sp|Q6PHH3|PDC10_BRARE Programmed cell death protein 10
Length = 205
Score = 113 bits (283), Expect = 6e-25
Identities = 61/133 (45%), Positives = 90/133 (67%)
Frame = +2
Query: 125 EVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIK 304
E++ +E+ LRMA+ + + ++ + L +A LK++LS+IPDEI+DR FL TIK
Sbjct: 66 EINFTESLLRMAADDVEEYMIDRPEREFQDLNERARALKQILSKIPDEINDRVRFLQTIK 125
Query: 305 EIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVY 484
+IASAIK LLD V+ V + +LE K++FVK+SK FS+TLK +F+D K V+
Sbjct: 126 DIASAIKELLDTVNNVFKKYQYQNRR-ALEHQKKEFVKHSKSFSDTLKTYFKDGKAINVF 184
Query: 485 ASANLLVNQTNMI 523
ASAN L++QTN+I
Sbjct: 185 ASANRLIHQTNLI 197
>sp|Q5ZIV5|PDC10_CHICK Programmed cell death protein 10
Length = 212
Score = 112 bits (281), Expect = 1e-24
Identities = 62/133 (46%), Positives = 88/133 (66%)
Frame = +2
Query: 125 EVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTLKEVLSRIPDEISDRRSFLDTIK 304
+V+ +E+ LRMA+ + + + L KA LK++LS+IPDEI+DR FL TIK
Sbjct: 73 DVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIK 132
Query: 305 EIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVY 484
+IASAIK LLD V+ V ++ +LE K++FVKYSK FS+TLK +F+D K V+
Sbjct: 133 DIASAIKELLDTVNNVFKKYQYQ-NRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVF 191
Query: 485 ASANLLVNQTNMI 523
SAN L++QTN+I
Sbjct: 192 ISANRLIHQTNLI 204
>sp|P35875|PARP_DROME Poly [ADP-ribose] polymerase (PARP) (ADPRT) (NAD(+)
ADP-ribosyltransferase) (Poly[ADP-ribose] synthetase)
Length = 994
Score = 35.8 bits (81), Expect = 0.15
Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 22/147 (14%)
Frame = +2
Query: 62 NIQDFLK-IFLIGILNKLGLENEVDMSETFLRMASMAETGVVRNMRKQIYNLLESKAHTL 238
++Q+ +K IF I +NK +E +DM + L S + + K+IYN+LE ++T
Sbjct: 650 SVQNLIKLIFDIDSMNKTLMEFHIDMDKMPLGKLSAHQIQSAYRVVKEIYNVLECGSNTA 709
Query: 239 KEV--------------------LSRIPDEISDRRSFLDTIKEIASAIKNL-LDCVSEVI 355
K + L +I D R LD++ EI A + + VS+
Sbjct: 710 KLIDATNRFYTLIPHNFGVQLPTLIETHQQIEDLRQMLDSLAEIEVAYSIIKSEDVSDAC 769
Query: 356 THLPTDGHKTSLEQAKRDFVKYSKRFS 436
P D H ++ K S+ FS
Sbjct: 770 N--PLDNHYAQIKTQLVALDKNSEEFS 794
>sp|O42649|SMC3_SCHPO Structural maintenance of chromosome 3 (Cohesin complex Psm3 subunit)
Length = 1194
Score = 35.0 bits (79), Expect = 0.26
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 2/113 (1%)
Frame = +2
Query: 107 KLGLENEVDMSETFLRMASMAETGVVRNMRKQIYNL--LESKAHTLKEVLSRIPDEISDR 280
++G +N +D SE V R++ K L ++S + L+E + RI EISD+
Sbjct: 835 EIGSDNRIDESEL---------NSVKRSLLKYENKLQIIKSSSSGLEEQMQRINSEISDK 885
Query: 281 RSFLDTIKEIASAIKNLLDCVSEVITHLPTDGHKTSLEQAKRDFVKYSKRFSN 439
R+ L++++E+ EV T + D AKR + K+ N
Sbjct: 886 RNELESLEELQ----------HEVATRIEQDAKINERNAAKRSLLLARKKECN 928
>sp|P29461|PTP2_YEAST Tyrosine-protein phosphatase 2 (Protein-tyrosine phosphatase 2)
(PTPase 2)
Length = 750
Score = 33.5 bits (75), Expect = 0.76
Identities = 16/48 (33%), Positives = 28/48 (58%)
Frame = +2
Query: 365 PTDGHKTSLEQAKRDFVKYSKRFSNTLKAFFRDNKPSEVYASANLLVN 508
P D +K L+ K+D + YS N+L+ FF+ N P+++ + +L N
Sbjct: 239 PNDSNKIFLQSLKKDLIHYS---PNSLQKFFQFNMPADLAPNDTILPN 283
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,147,043
Number of Sequences: 369166
Number of extensions: 1925125
Number of successful extensions: 5042
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4816
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5019
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)