Planarian EST Database


Dr_sW_011_A02

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_011_A02
         (919 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9GLE3|CATK_PIG  Cathepsin K precursor                         254   2e-67
sp|P43235|CATK_HUMAN  Cathepsin K precursor (Cathepsin O) (C...   253   5e-67
sp|P61277|CATK_MACMU  Cathepsin K precursor >gi|47117667|sp|...   253   5e-67
sp|P43236|CATK_RABIT  Cathepsin K precursor (OC-2 protein)        250   3e-66
sp|Q95029|CATL_DROME  Cathepsin L precursor (Cysteine protei...   250   3e-66
sp|Q24940|CATLP_FASHE  Cathepsin L-like proteinase precursor      250   4e-66
sp|P25782|CYSP2_HOMAM  Digestive cysteine proteinase 2 precu...   249   6e-66
sp|P55097|CATK_MOUSE  Cathepsin K precursor                       248   1e-65
sp|O35186|CATK_RAT  Cathepsin K precursor                         247   3e-65
sp|O60911|CATL2_HUMAN  Cathepsin L2 precursor (Cathepsin V) ...   246   8e-65
>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
          Length = 330

 Score =  254 bits (650), Expect = 2e-67
 Identities = 130/295 (44%), Positives = 189/295 (64%), Gaps = 7/295 (2%)
 Frame = +1

Query: 1   LIIIEFTQFITSHLIINEEFNAEWQVFKTKFNKNYTA-IDELVRKTIWIENIKYIQHHNV 177
           L ++     ++S L   E  + +W+++K  + K Y + +DE+ R+ IW +N+K+I  HN+
Sbjct: 4   LKVVLLLPVMSSALYPEEILDTQWELWKKTYRKQYNSKVDEISRRLIWEKNLKHISIHNL 63

Query: 178 KYDLGHHSHSLGINEFSDLTYKEFEK----LYLLSKNIEYNDGIDYLPPLNIDNLPDSVD 345
           +  LG H++ L +N   D+T +E  +    L +   +   ND + Y+P       PDS+D
Sbjct: 64  EASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSHSRSNDTL-YIPDWE-GRTPDSID 121

Query: 346 WRTKGYVTNVKNQGQCGSCWAFSTTGSLEGQHFRKHKVLQNISEQQLVDCVTKNSGCNGG 525
           +R KGYVT VKNQGQCGSCWAFS+ G+LEGQ  +K   L N+S Q LVDCV++N GC GG
Sbjct: 122 YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG 181

Query: 526 WMNIAFEYI-SSHGIESEDNYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVA 702
           +M  AF+Y+  + GI+SED YPY  +  NC+++ +   A C+G++ I   NEK L  AVA
Sbjct: 182 YMTNAFQYVQKNRGIDSEDAYPYVGQDENCMYNPTGKAAKCRGYREIPEGNEKALKRAVA 241

Query: 703 TVGPISVAIDVGY-SFQQYKQGVYYEAKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
            VGP+SVAID    SFQ Y +GVYY+  C+    NHAVL VGYG++ G K+W++K
Sbjct: 242 RVGPVSVAIDASLTSFQFYSKGVYYDENCNSDNLNHAVLAVGYGIQKGKKHWIIK 296

 Score = 30.0 bits (66), Expect = 9.5
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +3

Query: 864 NSWGPSWGMNGYIKMSKD 917
           NSWG +WG  GYI M+++
Sbjct: 297 NSWGENWGNKGYILMARN 314
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
          Length = 329

 Score =  253 bits (646), Expect = 5e-67
 Identities = 128/277 (46%), Positives = 182/277 (65%), Gaps = 6/277 (2%)
 Frame = +1

Query: 52  EEFNAEWQVFKTKFNKNYT-AIDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFS 228
           E  +  W+++K    K Y   +DE+ R+ IW +N+KYI  HN++  LG H++ L +N   
Sbjct: 20  EILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLG 79

Query: 229 DLTYKEF-EKLYLLSKNIEYNDGID--YLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCGS 399
           D+T +E  +K+  L   + ++   D  Y+P       PDSVD+R KGYVT VKNQGQCGS
Sbjct: 80  DMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWE-GRAPDSVDYRKKGYVTPVKNQGQCGS 138

Query: 400 CWAFSTTGSLEGQHFRKHKVLQNISEQQLVDCVTKNSGCNGGWMNIAFEYI-SSHGIESE 576
           CWAFS+ G+LEGQ  +K   L N+S Q LVDCV++N GC GG+M  AF+Y+  + GI+SE
Sbjct: 139 CWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSE 198

Query: 577 DNYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQ 753
           D YPY  ++ +C+++ +   A C+G++ I   NEK L  AVA VGP+SVAID    SFQ 
Sbjct: 199 DAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 258

Query: 754 YKQGVYYEAKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
           Y +GVYY+  C+    NHAVL VGYG++ G+K+W++K
Sbjct: 259 YSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295

 Score = 30.0 bits (66), Expect = 9.5
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +3

Query: 864 NSWGPSWGMNGYIKMSKD 917
           NSWG +WG  GYI M+++
Sbjct: 296 NSWGENWGNKGYILMARN 313
>sp|P61277|CATK_MACMU Cathepsin K precursor
 sp|P61276|CATK_MACFA Cathepsin K precursor
          Length = 329

 Score =  253 bits (646), Expect = 5e-67
 Identities = 128/278 (46%), Positives = 183/278 (65%), Gaps = 7/278 (2%)
 Frame = +1

Query: 52  EEFNAEWQVFKTKFNKNYTA-IDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFS 228
           E  +  W+++K    K Y + +DE+ R+ IW +N+KYI  HN++  LG H++ L +N   
Sbjct: 20  EILDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLG 79

Query: 229 DLTYKEFEK----LYLLSKNIEYNDGIDYLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCG 396
           D+T +E  +    L + + +   ND + Y+P       PDSVD+R KGYVT VKNQGQCG
Sbjct: 80  DMTNEEVVQKMTGLKVPASHSRSNDTL-YIPDWE-GRAPDSVDYRKKGYVTPVKNQGQCG 137

Query: 397 SCWAFSTTGSLEGQHFRKHKVLQNISEQQLVDCVTKNSGCNGGWMNIAFEYI-SSHGIES 573
           SCWAFS+ G+LEGQ  +K   L N+S Q LVDCV++N GC GG+M  AF+Y+  + GI+S
Sbjct: 138 SCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDS 197

Query: 574 EDNYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQ 750
           ED YPY  ++ +C+++ +   A C+G++ I   NEK L  AVA VGP+SVAID    SFQ
Sbjct: 198 EDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQ 257

Query: 751 QYKQGVYYEAKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
            Y +GVYY+  C+    NHAVL VGYG++ G+K+W++K
Sbjct: 258 FYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295

 Score = 30.0 bits (66), Expect = 9.5
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +3

Query: 864 NSWGPSWGMNGYIKMSKD 917
           NSWG +WG  GYI M+++
Sbjct: 296 NSWGENWGNKGYILMARN 313
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
          Length = 329

 Score =  250 bits (639), Expect = 3e-66
 Identities = 126/278 (45%), Positives = 182/278 (65%), Gaps = 7/278 (2%)
 Frame = +1

Query: 52  EEFNAEWQVFKTKFNKNYTA-IDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFS 228
           E  + +W+++K  ++K Y + +DE+ R+ IW +N+K+I  HN++  LG H++ L +N   
Sbjct: 20  EILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLG 79

Query: 229 DLTYKEFEK----LYLLSKNIEYNDGIDYLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCG 396
           D+T +E  +    L +       ND + Y+P       PDS+D+R KGYVT VKNQGQCG
Sbjct: 80  DMTSEEVVQKMTGLKVPPSRSHSNDTL-YIPDWE-GRTPDSIDYRKKGYVTPVKNQGQCG 137

Query: 397 SCWAFSTTGSLEGQHFRKHKVLQNISEQQLVDCVTKNSGCNGGWMNIAFEYIS-SHGIES 573
           SCWAFS+ G+LEGQ  +K   L N+S Q LVDCV++N GC GG+M  AF+Y+  + GI+S
Sbjct: 138 SCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENYGCGGGYMTNAFQYVQRNRGIDS 197

Query: 574 EDNYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQ 750
           ED YPY  +  +C+++ +   A C+G++ I   NEK L  AVA VGP+SVAID    SFQ
Sbjct: 198 EDAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQ 257

Query: 751 QYKQGVYYEAKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
            Y +GVYY+  C     NHAVL VGYG++ G+K+W++K
Sbjct: 258 FYSKGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIK 295

 Score = 31.2 bits (69), Expect = 4.3
 Identities = 11/18 (61%), Positives = 14/18 (77%)
 Frame = +3

Query: 864 NSWGPSWGMNGYIKMSKD 917
           NSWG SWG  GYI M+++
Sbjct: 296 NSWGESWGNKGYILMARN 313
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
           L heavy chain; Cathepsin L light chain]
          Length = 341

 Score =  250 bits (639), Expect = 3e-66
 Identities = 140/281 (49%), Positives = 182/281 (64%), Gaps = 15/281 (5%)
 Frame = +1

Query: 67  EWQVFKTKFNKNYT-AIDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFSDLTYK 243
           EW  FK +  KNY    +E  R  I+ EN   I  HN ++  G  S  L +N+++DL + 
Sbjct: 28  EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHH 87

Query: 244 EFEKL-----YLLSKNIEYND----GIDYLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCG 396
           EF +L     Y L K +   D    G+ ++ P ++  LP SVDWRTKG VT VK+QG CG
Sbjct: 88  EFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCG 146

Query: 397 SCWAFSTTGSLEGQHFRKHKVLQNISEQQLVDCVTK--NSGCNGGWMNIAFEYISSH-GI 567
           SCWAFS+TG+LEGQHFRK  VL ++SEQ LVDC TK  N+GCNGG M+ AF YI  + GI
Sbjct: 147 SCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGI 206

Query: 568 ESEDNYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-S 744
           ++E +YPY+A   +C F+K  V A  +GF +I   +EK +A AVATVGP+SVAID  + S
Sbjct: 207 DTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHES 266

Query: 745 FQQYKQGVYYEAKCDPTIQNHAVLVVGYGV-ENGHKYWLVK 864
           FQ Y +GVY E +CD    +H VLVVG+G  E+G  YWLVK
Sbjct: 267 FQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVK 307
>sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor
          Length = 326

 Score =  250 bits (638), Expect = 4e-66
 Identities = 116/269 (43%), Positives = 172/269 (63%), Gaps = 4/269 (1%)
 Frame = +1

Query: 70  WQVFKTKFNKNYTAIDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFSDLTYKEF 249
           W  +K  +NK Y   D+  R+ IW +N+K+IQ HN+++DLG  +++LG+N+F+D+T++EF
Sbjct: 21  WHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEF 80

Query: 250 EKLYLLSKNIEYNDGIDYLPPLNIDN--LPDSVDWRTKGYVTNVKNQGQCGSCWAFSTTG 423
           +  YL   +   +D + +  P   +N  +PD +DWR  GYVT VK+QG CGSCWAFSTTG
Sbjct: 81  KAKYLTEMS-RASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTG 139

Query: 424 SLEGQHFRKHKVLQNISEQQLVDCVTK--NSGCNGGWMNIAFEYISSHGIESEDNYPYQA 597
           ++EGQ+ +  +   + SEQQLVDC     N+GC+GG M  A++Y+   G+E+E +YPY A
Sbjct: 140 TMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTA 199

Query: 598 KQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGYSFQQYKQGVYYE 777
            +G C ++K   VA   G+  ++S +E +L   V    P +VA+DV   F  Y+ G+Y  
Sbjct: 200 VEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQS 259

Query: 778 AKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
             C P   NHAVL VGYG + G  YW+VK
Sbjct: 260 QTCSPLRVNHAVLAVGYGTQGGTDYWIVK 288

 Score = 30.4 bits (67), Expect = 7.3
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +3

Query: 864 NSWGPSWGMNGYIKMSKD 917
           NSWG  WG  GYI+M+++
Sbjct: 289 NSWGTYWGERGYIRMARN 306
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
          Length = 323

 Score =  249 bits (637), Expect = 6e-66
 Identities = 133/272 (48%), Positives = 172/272 (63%), Gaps = 7/272 (2%)
 Frame = +1

Query: 70  WQVFKTKFNKNYT-AIDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFSDLTYKE 246
           W+ FK K+ + Y  A ++  R+ I+ +N KYI+  N KY+ G  + +L +N+F D+T +E
Sbjct: 20  WEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYIEEFNKKYENGEVTFNLAMNKFGDMTLEE 79

Query: 247 FEKLYLLSKNIEYNDG--IDYLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCGSCWAFSTT 420
           F  +  +  NI         + P          VDWRTKG VT VK+QGQCGSCWAFSTT
Sbjct: 80  FNAV--MKGNIPRRSAPVSVFYPKKETGPQATEVDWRTKGAVTPVKDQGQCGSCWAFSTT 137

Query: 421 GSLEGQHFRKHKVLQNISEQQLVDCVTK--NSGCNGGWMNIAFEYI-SSHGIESEDNYPY 591
           GSLEGQHF K   L +++EQQLVDC       GCNGGWMN AF+YI +++GI++E  YPY
Sbjct: 138 GSLEGQHFLKTGSLISLAEQQLVDCSRPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPY 197

Query: 592 QAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQYKQGV 768
           +A+ G+C FD + V A C G  NI S +E  L  AV  +GPISV ID  + SFQ Y  GV
Sbjct: 198 EARDGSCRFDSNSVAATCSGHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGV 257

Query: 769 YYEAKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
           YYE  C P+  +HAVL VGYG E G  +WLVK
Sbjct: 258 YYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVK 289

 Score = 31.6 bits (70), Expect = 3.3
 Identities = 12/18 (66%), Positives = 14/18 (77%)
 Frame = +3

Query: 864 NSWGPSWGMNGYIKMSKD 917
           NSW  SWG  GYIKMS++
Sbjct: 290 NSWATSWGDAGYIKMSRN 307
>sp|P55097|CATK_MOUSE Cathepsin K precursor
          Length = 329

 Score =  248 bits (634), Expect = 1e-65
 Identities = 126/277 (45%), Positives = 178/277 (64%), Gaps = 6/277 (2%)
 Frame = +1

Query: 52  EEFNAEWQVFKTKFNKNYTA-IDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFS 228
           E  + +W+++K    K Y + +DE+ R+ IW +N+K I  HN++  LG H++ L +N   
Sbjct: 20  EMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLG 79

Query: 229 DLTYKEFEKLYL---LSKNIEYNDGIDYLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCGS 399
           D+T +E  +      +  +  Y++   Y P      +PDS+D+R KGYVT VKNQGQCGS
Sbjct: 80  DMTSEEVVQKMTGLRIPPSRSYSNDTLYTPEWE-GRVPDSIDYRKKGYVTPVKNQGQCGS 138

Query: 400 CWAFSTTGSLEGQHFRKHKVLQNISEQQLVDCVTKNSGCNGGWMNIAFEYISSH-GIESE 576
           CWAFS+ G+LEGQ  +K   L  +S Q LVDCVT+N GC GG+M  AF+Y+  + GI+SE
Sbjct: 139 CWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENYGCGGGYMTTAFQYVQQNGGIDSE 198

Query: 577 DNYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQ 753
           D YPY  +  +C+++ +   A C+G++ I   NEK L  AVA VGPISV+ID    SFQ 
Sbjct: 199 DAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQF 258

Query: 754 YKQGVYYEAKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
           Y +GVYY+  CD    NHAVLVVGYG + G K+W++K
Sbjct: 259 YSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIK 295
>sp|O35186|CATK_RAT Cathepsin K precursor
          Length = 329

 Score =  247 bits (631), Expect = 3e-65
 Identities = 124/277 (44%), Positives = 179/277 (64%), Gaps = 6/277 (2%)
 Frame = +1

Query: 52  EEFNAEWQVFKTKFNKNYTA-IDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFS 228
           E  + +W+++K    K Y + +DE+ R+ IW +N+K I  HN++  LG H++ L +N   
Sbjct: 20  ETLDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEASLGAHTYELAMNHLG 79

Query: 229 DLTYKEFEKLYL---LSKNIEYNDGIDYLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCGS 399
           D+T +E  +      +  +  +++   Y P      +PDS+D+R KGYVT VKNQGQCGS
Sbjct: 80  DMTSEEVVQKMTGLRVPPSRSFSNDTLYTPEWE-GRVPDSIDYRKKGYVTPVKNQGQCGS 138

Query: 400 CWAFSTTGSLEGQHFRKHKVLQNISEQQLVDCVTKNSGCNGGWMNIAFEYISSH-GIESE 576
           CWAFS+ G+LEGQ  +K   L  +S Q LVDCV++N GC GG+M  AF+Y+  + GI+SE
Sbjct: 139 CWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSENYGCGGGYMTTAFQYVQQNGGIDSE 198

Query: 577 DNYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQ 753
           D YPY  +  +C+++ +   A C+G++ I   NEK L  AVA VGP+SV+ID    SFQ 
Sbjct: 199 DAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPVSVSIDASLTSFQF 258

Query: 754 YKQGVYYEAKCDPTIQNHAVLVVGYGVENGHKYWLVK 864
           Y +GVYY+  CD    NHAVLVVGYG + G+KYW++K
Sbjct: 259 YSRGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIK 295
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
          Length = 334

 Score =  246 bits (627), Expect = 8e-65
 Identities = 132/280 (47%), Positives = 175/280 (62%), Gaps = 8/280 (2%)
 Frame = +1

Query: 49  NEEFNAEWQVFKTKFNKNYTAIDELVRKTIWIENIKYIQHHNVKYDLGHHSHSLGINEFS 228
           ++  + +W  +K    + Y A +E  R+ +W +N+K I+ HN +Y  G H  ++ +N F 
Sbjct: 22  DQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFG 81

Query: 229 DLTYKEFEKLYLLSKNIEYNDGIDYLPPLNIDNLPDSVDWRTKGYVTNVKNQGQCGSCWA 408
           D+T +EF ++    +N ++  G  +  PL +D LP SVDWR KGYVT VKNQ QCGSCWA
Sbjct: 82  DMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVKNQKQCGSCWA 140

Query: 409 FSTTGSLEGQHFRKHKVLQNISEQQLVDCVTK--NSGCNGGWMNIAFEYISSH-GIESED 579
           FS TG+LEGQ FRK   L ++SEQ LVDC     N GCNGG+M  AF+Y+  + G++SE+
Sbjct: 141 FSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEE 200

Query: 580 NYPYQAKQGNCVFDKSKVVANCKGFQNINSCNEKDLAVAVATVGPISVAIDVGY-SFQQY 756
           +YPY A    C +     VAN  GF  +    EK L  AVATVGPISVA+D G+ SFQ Y
Sbjct: 201 SYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFY 260

Query: 757 KQGVYYEAKCDPTIQNHAVLVVGYGVE----NGHKYWLVK 864
           K G+Y+E  C     +H VLVVGYG E    N  KYWLVK
Sbjct: 261 KSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = +3

Query: 864 NSWGPSWGMNGYIKMSKD 917
           NSWGP WG NGY+K++KD
Sbjct: 301 NSWGPEWGSNGYVKIAKD 318
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,421,227
Number of Sequences: 369166
Number of extensions: 2262744
Number of successful extensions: 7094
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6012
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6503
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9366655350
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)