Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_010_O13-2 (130 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9CS42|PRPS2_MOUSE Ribose-phosphate pyrophosphokinase II... 58 6e-09 sp|P21108|PRPS3_HUMAN Ribose-phosphate pyrophosphokinase II... 57 1e-08 sp|P09330|PRPS2_RAT Ribose-phosphate pyrophosphokinase II (... 57 1e-08 sp|Q4R4R7|PRPS2_MACFA Ribose-phosphate pyrophosphokinase II... 57 2e-08 sp|P60891|PRPS1_HUMAN Ribose-phosphate pyrophosphokinase I ... 56 2e-08 sp|Q9D7G0|PRPS1_MOUSE Ribose-phosphate pyrophosphokinase I ... 56 2e-08 sp|P65235|KPRS_NEIMB Ribose-phosphate pyrophosphokinase (RP... 36 0.031 sp|Q12265|KPR5_YEAST Probable ribose-phosphate pyrophosphok... 36 0.031 sp|Q899I8|KPRS_CLOTE Ribose-phosphate pyrophosphokinase (RP... 35 0.054 sp|P38689|KPR3_YEAST Ribose-phosphate pyrophosphokinase 3 (... 35 0.070
>sp|Q9CS42|PRPS2_MOUSE Ribose-phosphate pyrophosphokinase II (Phosphoribosyl pyrophosphate synthetase II) (PRS-II) Length = 318 Score = 58.2 bits (139), Expect = 6e-09 Identities = 28/43 (65%), Positives = 34/43 (79%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVSM 129 IFSGPAISRI S+ F A+VVTNTI Q+ MK +K+Q ID+SM Sbjct: 252 IFSGPAISRINSAAFEAVVVTNTIPQEDKMKHCSKIQVIDISM 294
>sp|P21108|PRPS3_HUMAN Ribose-phosphate pyrophosphokinase III (Phosphoribosyl pyrophosphate synthetase III) (PRS-III) (Phosphoribosyl pyrophosphate synthetase 1-like 1) Length = 318 Score = 57.0 bits (136), Expect = 1e-08 Identities = 27/43 (62%), Positives = 35/43 (81%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVSM 129 IFSGPAISRI ++ F A+VVTNTI QD+ MK +K++ ID+SM Sbjct: 252 IFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISM 294
>sp|P09330|PRPS2_RAT Ribose-phosphate pyrophosphokinase II (Phosphoribosyl pyrophosphate synthetase II) (PRS-II) Length = 318 Score = 57.0 bits (136), Expect = 1e-08 Identities = 27/43 (62%), Positives = 34/43 (79%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVSM 129 IFSGPAISRI ++ F A+VVTNTI Q+ MK +K+Q ID+SM Sbjct: 252 IFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCSKIQVIDISM 294
>sp|Q4R4R7|PRPS2_MACFA Ribose-phosphate pyrophosphokinase II (Phosphoribosyl pyrophosphate synthetase II) (PRS-II) sp|P11908|PRPS2_HUMAN Ribose-phosphate pyrophosphokinase II (Phosphoribosyl pyrophosphate synthetase II) (PRS-II) (PPRibP) Length = 318 Score = 56.6 bits (135), Expect = 2e-08 Identities = 27/43 (62%), Positives = 33/43 (76%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVSM 129 IFSGPAISRI ++ F A+VVTNTI Q+ MK K+Q ID+SM Sbjct: 252 IFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISM 294
>sp|P60891|PRPS1_HUMAN Ribose-phosphate pyrophosphokinase I (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) (PPRibP) sp|P60892|PRPS1_RAT Ribose-phosphate pyrophosphokinase I (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) Length = 318 Score = 56.2 bits (134), Expect = 2e-08 Identities = 27/43 (62%), Positives = 34/43 (79%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVSM 129 IFSGPAISRI ++ F A+VVTNTI Q+ MK +K+Q ID+SM Sbjct: 252 IFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISM 294
>sp|Q9D7G0|PRPS1_MOUSE Ribose-phosphate pyrophosphokinase I (Phosphoribosyl pyrophosphate synthetase I) (PRS-I) Length = 318 Score = 56.2 bits (134), Expect = 2e-08 Identities = 27/43 (62%), Positives = 34/43 (79%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVSM 129 IFSGPAISRI ++ F A+VVTNTI Q+ MK +K+Q ID+SM Sbjct: 252 IFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISM 294
>sp|P65235|KPRS_NEIMB Ribose-phosphate pyrophosphokinase (RPPK) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase) sp|P65234|KPRS_NEIMA Ribose-phosphate pyrophosphokinase (RPPK) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase) Length = 327 Score = 35.8 bits (81), Expect = 0.031 Identities = 15/42 (35%), Positives = 28/42 (66%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVS 126 +FSG A+SRI SS+ +VVT+TI + K ++++ + ++ Sbjct: 254 VFSGEAVSRIASSEIDQVVVTDTIPLSEAAKNCDRIRQVTIA 295
>sp|Q12265|KPR5_YEAST Probable ribose-phosphate pyrophosphokinase 5 (Phosphoribosyl pyrophosphate synthetase 5) Length = 496 Score = 35.8 bits (81), Expect = 0.031 Identities = 16/44 (36%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQ--SNKVQCIDVS 126 +FSG A+ RI S ++++NT+ QD+ ++ ++V IDVS Sbjct: 429 VFSGDALERIGQSSIDKLIISNTVPQDRTLQYLGKDRVDVIDVS 472
>sp|Q899I8|KPRS_CLOTE Ribose-phosphate pyrophosphokinase (RPPK) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase) Length = 320 Score = 35.0 bits (79), Expect = 0.054 Identities = 16/42 (38%), Positives = 28/42 (66%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVS 126 + SGPA+ RI++S ++ NTID K+ K S+K++ + V+ Sbjct: 259 VLSGPAMERIDNSVIKELITLNTIDISKI-KPSDKIKVLSVA 299
>sp|P38689|KPR3_YEAST Ribose-phosphate pyrophosphokinase 3 (Phosphoribosyl pyrophosphate synthetase 3) Length = 320 Score = 34.7 bits (78), Expect = 0.070 Identities = 16/42 (38%), Positives = 26/42 (61%) Frame = +1 Query: 1 IFSGPAISRIESSKFTAIVVTNTIDQDKVMKQSNKVQCIDVS 126 + SG AI I +SK +V TNT+ ++ +K+ K+ ID+S Sbjct: 254 VLSGRAIENINNSKLDRVVCTNTVPFEEKIKKCPKLAVIDIS 295
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.317 0.128 0.337 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,085,985 Number of Sequences: 369166 Number of extensions: 91394 Number of successful extensions: 307 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 306 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 307 length of database: 68,354,980 effective HSP length: 16 effective length of database: 65,399,220 effective search space used: 1700379720 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)