Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_O06
(862 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P57784|RU2A_MOUSE U2 small nuclear ribonucleoprotein A' ... 164 2e-40
sp|Q4R8Y8|RU2A_MACFA U2 small nuclear ribonucleoprotein A' ... 164 4e-40
sp|P43333|RU2A_ARATH U2 small nuclear ribonucleoprotein A' ... 147 3e-35
sp|Q9V4Q8|RU2A_DROME Probable U2 small nuclear ribonucleopr... 137 4e-32
sp|Q9BLB6|RU2A_CAEEL Probable U2 small nuclear ribonucleopr... 135 1e-31
sp|Q9USX8|RU2A_SCHPO U2 small nuclear ribonucleoprotein A' ... 116 7e-26
sp|Q08963|RU2A_YEAST U2 small nuclear ribonucleoprotein A' ... 57 5e-08
sp|Q9D3R3|CEP72_MOUSE Centrosomal protein of 72 kDa (Cep72 ... 50 1e-05
sp|Q755D2|RU2A_ASHGO U2 small nuclear ribonucleoprotein A' ... 47 5e-05
sp|Q9P209|CEP72_HUMAN Centrosomal protein of 72 kDa (Cep72 ... 43 0.001
>sp|P57784|RU2A_MOUSE U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
Length = 255
Score = 164 bits (416), Expect = 2e-40
Identities = 90/220 (40%), Positives = 130/220 (59%), Gaps = 5/220 (2%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
KI +IENLG TLDQFDA+DF+DNEI + DGFP L+RLK++ NN+I +I + L+ +P
Sbjct: 30 KIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPC 89
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSR 360
EL ++D LA K L +L++L+NP+ + +YRLYVI+K+PQVR+LDF +
Sbjct: 90 LTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQK 149
Query: 361 VKDKERKQAAYLFAGKAGDSTGKQKTIIVNGKPKPSEIENIPVVHEQMEIDPSK--PVLK 534
VK KER++A +F GK G K + +P P K
Sbjct: 150 VKLKERQEAEKMFKGKRGAQLAKD------------------IARRSKTFNPGAGLPTDK 191
Query: 535 K---PTISDMQALKAAIQNATSMEEVDRLNYILNSGKFAG 645
K P+ D++A+K AI NA+++ EV+RL +L SG+ G
Sbjct: 192 KKGGPSAGDVEAIKNAIANASTLAEVERLKGLLQSGQIPG 231
>sp|Q4R8Y8|RU2A_MACFA U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
sp|P09661|RU2A_HUMAN U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
Length = 255
Score = 164 bits (414), Expect = 4e-40
Identities = 90/220 (40%), Positives = 130/220 (59%), Gaps = 5/220 (2%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
KI +IENLG TLDQFDA+DF+DNEI + DGFP L+RLK++ NN+I +I + L+ +P
Sbjct: 30 KIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPC 89
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSR 360
EL ++D LA K L +L++L+NP+ + +YRLYVI+K+PQVR+LDF +
Sbjct: 90 LTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQK 149
Query: 361 VKDKERKQAAYLFAGKAGDSTGKQKTIIVNGKPKPSEIENIPVVHEQMEIDPSK--PVLK 534
VK KER++A +F GK G K + +P P K
Sbjct: 150 VKLKERQEAEKMFKGKRGAQLAKD------------------IARRSKTFNPGAGLPTDK 191
Query: 535 K---PTISDMQALKAAIQNATSMEEVDRLNYILNSGKFAG 645
K P+ D++A+K AI NA+++ EV+RL +L SG+ G
Sbjct: 192 KKGGPSPGDVEAIKNAIANASTLAEVERLKGLLQSGQIPG 231
>sp|P43333|RU2A_ARATH U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
Length = 249
Score = 147 bits (372), Expect = 3e-35
Identities = 84/212 (39%), Positives = 120/212 (56%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
KI +IENLG T DQFD +D +DNEI + + FP+L RL ++ NN+I +I +L F+P
Sbjct: 30 KIPVIENLGATEDQFDTIDLSDNEIVKLENFPYLNRLGTLLINNNRITRINPNLGEFLPK 89
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSR 360
L EID LA L++L+LL N I ++NYRLYVIHKL +R+LDF +
Sbjct: 90 LHSLVLTNNRLVNLVEIDPLASIPKLQYLSLLDNNITKKANYRLYVIHKLKSLRVLDFIK 149
Query: 361 VKDKERKQAAYLFAGKAGDSTGKQKTIIVNGKPKPSEIENIPVVHEQMEIDPSKPVLKKP 540
+K KER +AA LF+ K + K K E++ + E +P P + P
Sbjct: 150 IKAKERAEAASLFSSKEAEEEVK--------KVSREEVKKVSETAE----NPETPKVVAP 197
Query: 541 TISDMQALKAAIQNATSMEEVDRLNYILNSGK 636
T + A+KAAI N+ ++EE+ RL L G+
Sbjct: 198 TAEQILAIKAAIINSQTIEEIARLEQALKFGQ 229
>sp|Q9V4Q8|RU2A_DROME Probable U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
Length = 265
Score = 137 bits (345), Expect = 4e-32
Identities = 81/213 (38%), Positives = 121/213 (56%), Gaps = 1/213 (0%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
KI IENLG TLDQFD +D +DN++ + D P L RLK + NN+I++I++ L +P
Sbjct: 30 KIPQIENLGATLDQFDTIDLSDNDLRKLDNLPHLPRLKCLLLNNNRILRISEGLEEAVPN 89
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSR 360
QEL +++ L F LE + LL NP++T+ NYR Y+ +K PQ+R+LDF +
Sbjct: 90 LGSIILTGNNLQELSDLEPLVGFTKLETICLLINPVSTKPNYREYMAYKFPQLRLLDFRK 149
Query: 361 VKDKERKQAAYLFAGKAGDSTGKQKTIIVNGKPKPSEIENIPVVHEQMEIDPSK-PVLKK 537
+K K+R+ A F K G K+ ++ K K S I + S+ L
Sbjct: 150 IKQKDRQAAQEFFRTKQGKDVLKE----ISRKSKMSAAAAIAAEAGNGKGRGSEGGRLAN 205
Query: 538 PTISDMQALKAAIQNATSMEEVDRLNYILNSGK 636
P DMQ ++ AI+ A+S+ EV+RL+ IL SG+
Sbjct: 206 P--QDMQRIREAIKRASSLAEVERLSQILQSGQ 236
>sp|Q9BLB6|RU2A_CAEEL Probable U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
Length = 253
Score = 135 bits (341), Expect = 1e-31
Identities = 84/214 (39%), Positives = 119/214 (55%), Gaps = 2/214 (0%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
KI +IEN+G T DQFD +D TDN+I + D FP RL ++ NN+I IA D+ +P
Sbjct: 30 KIPVIENMGVTRDQFDVIDLTDNDIRKLDNFPTFSRLNTLYLHNNRINYIAPDIATKLPN 89
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSR 360
EL +I+ LA K LE++ + NPI + NYR+Y+I+KLP VR++DF+R
Sbjct: 90 LKTLALTNNNICELGDIEPLAECKKLEYVTFIGNPITHKDNYRMYMIYKLPTVRVIDFNR 149
Query: 361 VKDKERKQAAYLFAGKAGDST--GKQKTIIVNGKPKPSEIENIPVVHEQMEIDPSKPVLK 534
V+ ER+ A +F GK+G QK++ PSEIE + S
Sbjct: 150 VRLTEREAAKKMFKGKSGKKARDAIQKSVHTE---DPSEIE---------PNENSSGGGA 197
Query: 535 KPTISDMQALKAAIQNATSMEEVDRLNYILNSGK 636
+ T D + +K AI+NA S+ EV+ L IL SGK
Sbjct: 198 RLTDEDREKIKEAIKNAKSLSEVNYLQSILASGK 231
>sp|Q9USX8|RU2A_SCHPO U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
Length = 239
Score = 116 bits (291), Expect = 7e-26
Identities = 72/214 (33%), Positives = 120/214 (56%), Gaps = 2/214 (0%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
+I +IENLG D DA+DFTDN+I FP +KRL+++ NN+I IA D+ +P
Sbjct: 29 QIPIIENLGVLRDVHDAIDFTDNDIRYLGNFPRMKRLQTLLCGNNRITAIAPDIGKVLPN 88
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSR 360
QE+ ++D LA L L+ + NP+A + YRLY+I ++P + ILDF R
Sbjct: 89 LKTLSLAQNHLQEIADLDPLASCPQLTNLSCIDNPVAQKQYYRLYLIWRIPSLHILDFER 148
Query: 361 VKDKERKQAAYLFAGKAGDSTGKQKTIIVNGKPKPSEIENIPVVHEQMEIDPSKPVLKKP 540
V+ ER +A +F G+ + T + + I+ K + ++ + H + + P+
Sbjct: 149 VRRNERLRAEEVF-GQIQNPT-EIASSIMGVKSRVFDLAALVQSHP----EANSPITTGY 202
Query: 541 TIS--DMQALKAAIQNATSMEEVDRLNYILNSGK 636
T++ + + +K AI+NA+S+ E++RL +L GK
Sbjct: 203 TLTPEEREKIKEAIKNASSIAEINRLEAMLLEGK 236
>sp|Q08963|RU2A_YEAST U2 small nuclear ribonucleoprotein A' (U2 snRNP-A') (Looks
exceptionally like U2A protein 1)
Length = 238
Score = 57.4 bits (137), Expect = 5e-08
Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 2/130 (1%)
Frame = +1
Query: 250 KDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSRVKDKERKQAAYLFAGKAGDSTGK 429
+ L+ L L+ N + +NYR +V+ +P + LDF V +ERK A GD+ G
Sbjct: 122 RTLKNLTLIGNQVCHLANYREHVLRLVPHLETLDFQNVTAEERKSAMSFPRQADGDTLGP 181
Query: 430 QKTIIVN--GKPKPSEIENIPVVHEQMEIDPSKPVLKKPTISDMQALKAAIQNATSMEEV 603
T I + + K EI N+ V+ K T+ LK + ATS+EE+
Sbjct: 182 VNTAIRDNGSRDKTMEIMNL--------------VVSKMTVERRNELKKQLAEATSLEEI 227
Query: 604 DRLNYILNSG 633
RL +L+ G
Sbjct: 228 ARLEKLLSGG 237
>sp|Q9D3R3|CEP72_MOUSE Centrosomal protein of 72 kDa (Cep72 protein)
Length = 646
Score = 49.7 bits (117), Expect = 1e-05
Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
KI+ + N L +LD + N + +G +L L+S+N N I +A
Sbjct: 41 KITHLGNSLMHLTALKSLDLSRNSLVSLEGIQYLVSLESLNLYYNCISSLA--------- 91
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIA-TQSNYRLYVIHKLPQVRILDFS 357
E+ + L +D++F NP+ +S+YRL+V+H LP++R LD
Sbjct: 92 ------------EVFRLHTLLELQDVDFRL---NPVVKNESDYRLFVVHMLPKLRQLDDR 136
Query: 358 RVKDKERKQAAYLFAGKAG-DSTGKQKTIIVNGKP 459
V++ ERK + FA + +S T + G+P
Sbjct: 137 PVRESERKASQLHFAPEDSLNSKENFSTTLTVGRP 171
>sp|Q755D2|RU2A_ASHGO U2 small nuclear ribonucleoprotein A' (U2 snRNP-A')
Length = 237
Score = 47.4 bits (111), Expect = 5e-05
Identities = 43/200 (21%), Positives = 87/200 (43%), Gaps = 1/200 (0%)
Frame = +1
Query: 37 DQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKI-AKDLNNFIPXXXXXXXXXXXX 213
++ + +DFT+NE+ + ++ + N++ ++ A L ++
Sbjct: 52 ERTNIVDFTNNELEELPPLGHNDTVHTLLLSRNRLGRLDASRLPRYLVNLNLAMNRFEKF 111
Query: 214 QELKEIDNLACFKDLEFLALLKNPIATQSNYRLYVIHKLPQVRILDFSRVKDKERKQAAY 393
++L+ + + K L+ L L N I + YR VI PQ+ +LD RV+ ER+ A
Sbjct: 112 EQLQGLRSAP--KTLKNLNLRGNVICHKEQYRETVIALCPQLAVLDGERVRQAERQAAPQ 169
Query: 394 LFAGKAGDSTGKQKTIIVNGKPKPSEIENIPVVHEQMEIDPSKPVLKKPTISDMQALKAA 573
+KT P+P ++ + E+ V+ K ++ +K
Sbjct: 170 -----------NEKTDTPTEGPQPVALQ----ATSEKELQLMDHVVNKMDKDTLEDIKQQ 214
Query: 574 IQNATSMEEVDRLNYILNSG 633
+ AT++ E++RL +L+ G
Sbjct: 215 LAKATTLAEIERLEKLLSGG 234
>sp|Q9P209|CEP72_HUMAN Centrosomal protein of 72 kDa (Cep72 protein)
Length = 647
Score = 43.1 bits (100), Expect = 0.001
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 2/155 (1%)
Frame = +1
Query: 1 KISLIENLGTTLDQFDALDFTDNEIHRFDGFPFLKRLKSINFTNNKIVKIAKDLNNFIPX 180
KI+ + + +L +LD + N + +G +L L+S+N N I +A
Sbjct: 42 KITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLA--------- 92
Query: 181 XXXXXXXXXXXQELKEIDNLACFKDLEFLALLKNPIA-TQSNYRLYVIHKLPQVRILDFS 357
E+ L +L + NP+ + +YRL+V+H LP+++ LD
Sbjct: 93 ---------------EVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDR 137
Query: 358 RVKDKERKQAAYLFAGKAG-DSTGKQKTIIVNGKP 459
V+ ERK + FA + DS + G+P
Sbjct: 138 PVRASERKASRLHFASEDSLDSKESVPASLKEGRP 172
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,821,168
Number of Sequences: 369166
Number of extensions: 1783583
Number of successful extensions: 5441
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5254
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5438
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8534739105
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)