Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_O05
(591 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P49900|ARGI_RANCA Arginase, hepatic 147 3e-35
sp|P05089|ARGI1_HUMAN Arginase-1 (Type I arginase) (Liver-t... 142 6e-34
sp|Q95JC8|ARGI1_PIG Arginase-1 (Type I arginase) (Liver-typ... 142 8e-34
sp|P37818|ARGI1_SCHPO Arginase 140 2e-33
sp|P07824|ARGI1_RAT Arginase-1 (Type I arginase) (Liver-typ... 140 3e-33
sp|P78540|ARGI2_HUMAN Arginase-2, mitochondrial precursor (... 139 5e-33
sp|Q91555|ARGN3_XENLA Arginase, non-hepatic 3 138 9e-33
sp|Q61176|ARGI1_MOUSE Arginase-1 (Type I arginase) (Liver-t... 137 2e-32
sp|Q91554|ARGN2_XENLA Arginase, non-hepatic 2 137 2e-32
sp|Q91553|ARGN1_XENLA Arginase, non-hepatic 1 135 8e-32
>sp|P49900|ARGI_RANCA Arginase, hepatic
Length = 323
Score = 147 bits (370), Expect = 3e-35
Identities = 76/144 (52%), Positives = 99/144 (68%), Gaps = 1/144 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P +SAK+IVYIGLR VDP E ++L IKS+SM D+DR IN V+++ I+ + R
Sbjct: 168 PSLSAKDIVYIGLRDVDPGEHYILKTLGIKSYSMSDVDRLTINKVMEETIEFLVGKKKRP 227
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVG-TY 361
HLSFDID LDP AP+TGT VPGGLT REG+Y+ EQL+NTG L+A+D+ E+N G T
Sbjct: 228 IHLSFDIDGLDPSVAPATGTPVPGGLTYREGMYITEQLYNTGLLSAVDMMEVNPSRGETE 287
Query: 362 SEVVTTINSATKIIQGCLGIKREG 433
E T+N++ +I C G REG
Sbjct: 288 RESKLTVNTSLNMILSCFGKAREG 311
>sp|P05089|ARGI1_HUMAN Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 322
Score = 142 bits (358), Expect = 6e-34
Identities = 70/144 (48%), Positives = 96/144 (66%), Gaps = 1/144 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P ISAK+IVYIGLR VDP E ++L IK FSM ++DR GI V+++ + + R
Sbjct: 167 PCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRP 226
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVG-TY 361
HLSFD+D LDP + P+TGT V GGLT REG+Y+ E+++ TG L+ +D+ E+N +G T
Sbjct: 227 IHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTP 286
Query: 362 SEVVTTINSATKIIQGCLGIKREG 433
EV T+N+A I C G+ REG
Sbjct: 287 EEVTRTVNTAVAITLACFGLAREG 310
>sp|Q95JC8|ARGI1_PIG Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 322
Score = 142 bits (357), Expect = 8e-34
Identities = 67/144 (46%), Positives = 97/144 (67%), Gaps = 1/144 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P +SAK+IVYIGLR VDP E ++L IK FSM ++D+ GI V+++A + R
Sbjct: 167 PCLSAKDIVYIGLRDVDPAEHYILKTLGIKYFSMIEVDKLGIGKVMEEAFSYLLGRKKRP 226
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVG-TY 361
HLSFD+D LDP + P+TGT V GGL+ REG+Y+ E+++ TG L+ +D+ E+N +G T
Sbjct: 227 IHLSFDVDGLDPFFTPATGTPVHGGLSYREGIYITEEIYKTGLLSGLDIMEVNPSLGKTP 286
Query: 362 SEVVTTINSATKIIQGCLGIKREG 433
EV T+N+A ++ C G+ REG
Sbjct: 287 EEVTRTVNTAVALVLACFGVAREG 310
>sp|P37818|ARGI1_SCHPO Arginase
Length = 323
Score = 140 bits (353), Expect = 2e-33
Identities = 64/137 (46%), Positives = 93/137 (67%)
Frame = +2
Query: 8 VISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRYF 187
VI + + +IGLR +DP ER L + +I +++M D+D+ GI V++ A++ +NP R
Sbjct: 183 VIEERRLAFIGLRDLDPMERAFLRERSITAYTMHDVDKYGIARVVEMALEHINPGRRRPI 242
Query: 188 HLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVGTYSE 367
HLSFD+DA DP+ AP+TGT VPGGLT RE +Y+CE + TG L A+DV E+N +G E
Sbjct: 243 HLSFDVDACDPIVAPATGTRVPGGLTFREAMYICESVAETGSLVAVDVMEVNPLLGNKEE 302
Query: 368 VVTTINSATKIIQGCLG 418
TT++ A I++ CLG
Sbjct: 303 AKTTVDLARSIVRTCLG 319
>sp|P07824|ARGI1_RAT Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 323
Score = 140 bits (352), Expect = 3e-33
Identities = 69/152 (45%), Positives = 98/152 (64%), Gaps = 1/152 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P ISAK+IVYIGLR VDP E +++ IK FSM ++D+ GI V+++ + R
Sbjct: 167 PCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRP 226
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVG-TY 361
HLSFD+D LDP++ P+TGT V GGL+ REG+Y+ E+++ TG L+ +D+ E+N +G T
Sbjct: 227 IHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTP 286
Query: 362 SEVVTTINSATKIIQGCLGIKREGAPLITPDY 457
EV T+N+A + C G KREG DY
Sbjct: 287 EEVTRTVNTAVALTLSCFGTKREGNHKPETDY 318
>sp|P78540|ARGI2_HUMAN Arginase-2, mitochondrial precursor (Arginase II) (Non-hepatic
arginase) (Kidney-type arginase)
Length = 354
Score = 139 bits (350), Expect = 5e-33
Identities = 73/148 (49%), Positives = 95/148 (64%), Gaps = 1/148 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P IS+ +IVYIGLR VDP E +L Y+I+ FSM DIDR GI V+++ + R
Sbjct: 186 PCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRP 245
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVGT-Y 361
HLSFDIDA DP AP+TGT V GGLT REG+Y+ E++ NTG L+A+D+ E+N Q+ T
Sbjct: 246 IHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSE 305
Query: 362 SEVVTTINSATKIIQGCLGIKREGAPLI 445
E TT N A +I G REG ++
Sbjct: 306 EEAKTTANLAVDVIASSFGQTREGGHIV 333
>sp|Q91555|ARGN3_XENLA Arginase, non-hepatic 3
Length = 360
Score = 138 bits (348), Expect = 9e-33
Identities = 73/145 (50%), Positives = 93/145 (64%), Gaps = 1/145 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P +S +IVYIGLR +DP E+ +L YNI +SM ID GI V+++ + DR
Sbjct: 188 PCLSKSDIVYIGLRDLDPAEQFILKNYNISYYSMRHIDCMGIRKVMEKTFDQLLGRRDRP 247
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVGTYS 364
HLSFDIDA DP AP+TGT V GGLT REGVY+ E++ NTG L+A+D+ E+N + T S
Sbjct: 248 IHLSFDIDAFDPALAPATGTPVIGGLTYREGVYITEEIHNTGMLSALDLVEVNPVLATTS 307
Query: 365 -EVVTTINSATKIIQGCLGIKREGA 436
EV T N A +I C G REGA
Sbjct: 308 EEVKATANLAVDVIASCFGQTREGA 332
>sp|Q61176|ARGI1_MOUSE Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 323
Score = 137 bits (345), Expect = 2e-32
Identities = 68/152 (44%), Positives = 98/152 (64%), Gaps = 1/152 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P ISAK+IVYIGLR VDP E +++ IK FSM ++D+ GI V+++ + R
Sbjct: 167 PCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRP 226
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQVG-TY 361
HLSFD+D LDP + P+TGT V GGL+ REG+Y+ E+++ TG L+ +D+ E+N +G T
Sbjct: 227 IHLSFDVDGLDPAFTPATGTPVLGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTA 286
Query: 362 SEVVTTINSATKIIQGCLGIKREGAPLITPDY 457
EV +T+N+A + C G +REG DY
Sbjct: 287 EEVKSTVNTAVALTLACFGTQREGNHKPGTDY 318
>sp|Q91554|ARGN2_XENLA Arginase, non-hepatic 2
Length = 360
Score = 137 bits (345), Expect = 2e-32
Identities = 72/145 (49%), Positives = 91/145 (62%), Gaps = 1/145 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P +S +IVYIGLR +DP E+ +L YNI +SM ID GI V+++ + DR
Sbjct: 188 PCLSKSDIVYIGLRDLDPAEQFILKNYNISYYSMRHIDCMGIKKVMEKTFDQLLGRRDRP 247
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEIN-TQVGTY 361
HLSFDIDA DP AP+TGT V GGLT REGVY+ E++ NTG L+A+D+ E+N T
Sbjct: 248 IHLSFDIDAFDPALAPATGTPVIGGLTYREGVYITEEIHNTGMLSAVDLVEVNPVLAATS 307
Query: 362 SEVVTTINSATKIIQGCLGIKREGA 436
EV T N A +I C G REGA
Sbjct: 308 EEVKATANLAVDVIASCFGQTREGA 332
>sp|Q91553|ARGN1_XENLA Arginase, non-hepatic 1
Length = 360
Score = 135 bits (340), Expect = 8e-32
Identities = 71/145 (48%), Positives = 91/145 (62%), Gaps = 1/145 (0%)
Frame = +2
Query: 5 PVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNPNLDRY 184
P +S +IVYIGLR +DP E+ +L Y+I +SM ID GI V+++ + DR
Sbjct: 188 PCLSKSDIVYIGLRDLDPAEQFILKNYDISYYSMRHIDCMGIKKVMEKTFDQLLGRRDRP 247
Query: 185 FHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEIN-TQVGTY 361
HLSFDIDA DP AP+TGT V GGLT REGVY+ E++ NTG L+A+D+ E+N T
Sbjct: 248 IHLSFDIDAFDPALAPATGTPVIGGLTYREGVYITEEIHNTGMLSAVDLVEVNPVLAATS 307
Query: 362 SEVVTTINSATKIIQGCLGIKREGA 436
EV T N A +I C G REGA
Sbjct: 308 EEVKATANLAVDVIASCFGQTREGA 332
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,718,569
Number of Sequences: 369166
Number of extensions: 1155179
Number of successful extensions: 3186
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3079
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3164
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4455160255
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)