Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_010_N07 (690 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O00233|PSD9_HUMAN 26S proteasome non-ATPase regulatory s... 95 2e-19 sp|Q9CR00|PSD9_MOUSE 26S proteasome non-ATPase regulatory s... 93 8e-19 sp|Q9WTV5|PSD9_RAT 26S proteasome non-ATPase regulatory sub... 91 3e-18 sp|Q10920|PSD9_CAEEL Probable 26S proteasome non-ATPase reg... 72 2e-12 sp|P40555|PSD9_YEAST Probable 26S proteasome regulatory sub... 48 3e-05 sp|Q8YQ64|Y3971_ANASP Hypothetical zinc metalloprotease All... 40 0.004 sp|Q9A710|MMPA_CAUCR Metalloprotease mmpA (membrane metallo... 37 0.064 sp|Q98MC1|Y638_RHILO Hypothetical zinc metalloprotease mll0638 35 0.14 sp|Q00702|UL20_PRVN3 UL20 membrane protein homolog 34 0.32 sp|O61967|LAP1_CAEEL Lap1 protein (Lethal protein 413) 34 0.42
>sp|O00233|PSD9_HUMAN 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27) Length = 223 Score = 95.1 bits (235), Expect = 2e-19 Identities = 55/178 (30%), Positives = 93/178 (52%), Gaps = 3/178 (1%) Frame = +3 Query: 105 QGVGVTRPLTDLEGFPLNNVDLFAIREARFRHNCLQNDLTAVMLEIESKLHEIHSLNVGL 284 +G+G+ PL D EG+P ++VDL+ +R AR CLQND AVM ++E LH++H+ + Sbjct: 48 KGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARD--- 104 Query: 285 ESSRAIDNAGENLSPEGRNDGSAAFIARHPPFARVDRVDASSVAFSCGLREGDELLQIDH 464 + +A D A + R G + FA+V+ + S A GL+ DE+++ Sbjct: 105 KEKQARDMAEAHKEAMSRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGS 164 Query: 465 ITKETFSGLQAVMELFRSRANKTVLVCVKRGNKRVHLTIVP---PSQGPIGCLLVPLQ 629 + + F L + + + K + V V R ++ L +VP +G +GC ++PLQ Sbjct: 165 VNTQNFQSLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQ 222
>sp|Q9CR00|PSD9_MOUSE 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27) Length = 222 Score = 92.8 bits (229), Expect = 8e-19 Identities = 57/183 (31%), Positives = 96/183 (52%), Gaps = 8/183 (4%) Frame = +3 Query: 105 QGVGVTRPLTDLEGFPLNNVDLFAIREARFRHNCLQNDLTAVMLEIESKLHEIHSLNVGL 284 +G+G+ PL D EG+P +VDL+ +R AR CLQND A+M ++E LH++H+ + Sbjct: 48 KGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHARD--- 104 Query: 285 ESSRAIDNAGENLSPEGRNDGSAAFIARHPP-----FARVDRVDASSVAFSCGLREGDEL 449 + +A D A E R + +A + P FARV+ + S A GL+ DE+ Sbjct: 105 KEKQARDMA------EAREEAMNRRLASNSPVLPQAFARVNSISPGSPASIAGLQVDDEI 158 Query: 450 LQIDHITKETFSGLQAVMELFRSRANKTVLVCVKRGNKRVHLTIVP---PSQGPIGCLLV 620 ++ + + F +Q V + + K + V V R ++ L ++P +G +GC ++ Sbjct: 159 VEFGSVNTQNFQSVQNVGTVVQHSEGKPLNVTVIRRGEKHQLRLIPTRWAGKGLLGCNII 218 Query: 621 PLQ 629 PLQ Sbjct: 219 PLQ 221
>sp|Q9WTV5|PSD9_RAT 26S proteasome non-ATPase regulatory subunit 9 (26S proteasome regulatory subunit p27) (Transactivating protein Bridge-1) Length = 222 Score = 90.9 bits (224), Expect = 3e-18 Identities = 55/178 (30%), Positives = 92/178 (51%), Gaps = 3/178 (1%) Frame = +3 Query: 105 QGVGVTRPLTDLEGFPLNNVDLFAIREARFRHNCLQNDLTAVMLEIESKLHEIHSLNVGL 284 +G+G+ PL D EG+P +VDL+ +R AR CLQND A+M ++E LH++H+ + Sbjct: 48 KGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHARDKEK 107 Query: 285 ESSRAIDNAGENLSPEGRNDGSAAFIARHPPFARVDRVDASSVAFSCGLREGDELLQIDH 464 ++ + E ++ +D A A FARV+ + S A GL+ DE+++ Sbjct: 108 QARDMAEAREEAMNRRLASDSPALPKA----FARVNSISPGSPASIAGLQVDDEIVEFGS 163 Query: 465 ITKETFSGLQAVMELFRSRANKTVLVCVKRGNKRVHLTIVP---PSQGPIGCLLVPLQ 629 + + F LQ V + + K + V V R ++ L + P +G +GC + PLQ Sbjct: 164 VNTQNFQSLQNVGTVVQHSEGKPLNVMVIRRGEKHQLRLTPTRWAGKGLLGCNITPLQ 221
>sp|Q10920|PSD9_CAEEL Probable 26S proteasome non-ATPase regulatory subunit 9 Length = 197 Score = 71.6 bits (174), Expect = 2e-12 Identities = 49/174 (28%), Positives = 81/174 (46%), Gaps = 7/174 (4%) Frame = +3 Query: 126 PLTDLEGFPLNNVDLFAIREARFRHNCLQNDLTA----VMLEIESKLHEIHSLNVGLESS 293 PL D EG+PLN +D++A+R AR CL+ND A +++E+E++ E+ E Sbjct: 38 PLLDAEGYPLNTIDVYAVRHARHDLICLRNDRAALTEKIVVEMENENKEVSGQTATSEEK 97 Query: 294 RAIDNAGENLSPEGRNDGSAAFIARHPPFARVDRVDASSVAFSCGLREGDELLQIDHITK 473 + E PF ++ V S A G R+ D ++Q ++ Sbjct: 98 PVHRTSNE-------------------PFVKISSVVELSPADIGGFRKDDLIIQYGNLHH 138 Query: 474 ETFSGLQAVMELFRSRANKTVLVCVKRGNKRVHLTIVP---PSQGPIGCLLVPL 626 F+ +Q V ++ + +K + V V R N+ V L I P G +GC +VP+ Sbjct: 139 GNFNDMQEVAQITKQSEDKIIRVTVIRENRPVRLEICPKKWSGPGLLGCNIVPI 192
>sp|P40555|PSD9_YEAST Probable 26S proteasome regulatory subunit p27 (Proteasome non-ATPase subunit 2) Length = 220 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/180 (21%), Positives = 80/180 (44%), Gaps = 4/180 (2%) Frame = +3 Query: 99 DSQGVGVTRPLTDLEGFPLNNVDLFAIREARFRHNCLQNDLTAVMLEIESKLHEIHSLNV 278 + QG+G+ L +G+P ++VD+ + R N L+NDL ++ L++ H N+ Sbjct: 53 EQQGIGMDSALVTPDGYPRSDVDVLQVTMIRKNVNMLKNDLNHLLQRSHVLLNQ-HFDNM 111 Query: 279 GLESSRAIDNAGENLSPEGRNDGSAAFIARHPPFARVDRVDASSVAFSCGLREGDELLQI 458 ++S++ + R + I PFA + V S + ++ D+L+ I Sbjct: 112 NVKSNQ-----------DARRNNDDQAIQYTIPFAFISEVVPGSPSDKADIKVDDKLISI 160 Query: 459 DHITKETFSGLQAVMELFRSRANKTVLVCVKRGNKRVHLTIVPP----SQGPIGCLLVPL 626 ++ S LQ + + ++ + V + R + + ++ P +G +GC + L Sbjct: 161 GNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREGQILKTSLTPSRNWNGRGLLGCRIQEL 220
>sp|Q8YQ64|Y3971_ANASP Hypothetical zinc metalloprotease All3971 Length = 364 Score = 40.4 bits (93), Expect = 0.004 Identities = 25/81 (30%), Positives = 47/81 (58%), Gaps = 6/81 (7%) Frame = +3 Query: 399 DASSVAFSCGLREGDELLQIDHITKETFSGLQ---AVMELFRSRANKTVLVCVKRGNKRV 569 + S+VA + GL+ GD +L + KE + LQ A+ ++ ++ K++ + V RG++R+ Sbjct: 135 EVSAVATNAGLKPGDVILSANQ--KEFGTSLQEIEALRDIIKNSPGKSIQLTVARGDERL 192 Query: 570 HLTIVP---PSQGPIGCLLVP 623 + ++P P+ G IG L P Sbjct: 193 SVNVIPEAKPAGGSIGIGLAP 213
>sp|Q9A710|MMPA_CAUCR Metalloprotease mmpA (membrane metalloprotease A) Length = 398 Score = 36.6 bits (83), Expect = 0.064 Identities = 22/67 (32%), Positives = 34/67 (50%) Frame = +3 Query: 387 VDRVDASSVAFSCGLREGDELLQIDHITKETFSGLQAVMELFRSRANKTVLVCVKRGNKR 566 V V A + A + G + GD +L+ D+ +F +Q + L RAN + V+R + Sbjct: 150 VGEVVAGTPAAAAGFKPGDVILKADNRQIRSFQDIQGYVAL---RANMPIDFAVERDGRT 206 Query: 567 VHLTIVP 587 VHLT P Sbjct: 207 VHLTATP 213
>sp|Q98MC1|Y638_RHILO Hypothetical zinc metalloprotease mll0638 Length = 367 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/67 (32%), Positives = 30/67 (44%) Frame = +3 Query: 387 VDRVDASSVAFSCGLREGDELLQIDHITKETFSGLQAVMELFRSRANKTVLVCVKRGNKR 566 V V A S A G++ GD + +D ETF +Q L RA T+ + R K Sbjct: 141 VAEVTADSPAAKAGIQPGDRFVSVDGSKVETFGDVQ---RLVSGRAGDTITFVMLRDGKE 197 Query: 567 VHLTIVP 587 V +T P Sbjct: 198 VTVTATP 204
>sp|Q00702|UL20_PRVN3 UL20 membrane protein homolog Length = 161 Score = 34.3 bits (77), Expect = 0.32 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Frame = +3 Query: 282 LESSRAIDNAGENLSPEGRNDG--SAAFIARHPPFARVDRVDASSVAFSCGLREGDELLQ 455 +E + A +A + G ND S+AF+ PP R S +A + LR L+ Sbjct: 1 MEDAAADVDAAADAKLTGENDALLSSAFVGARPPRPRFSSHVVSLLALALALRPACCLVL 60 Query: 456 IDHITKETFSGLQAVMELFRSRANKTVLVCVKRGNKRVHLTIVPPSQGPIGCL 614 H ++ T + L + + A VLV R R + + P Q +G L Sbjct: 61 ALHGSRATLAALLTALAFYARAAVCAVLVA--RNVARDRMPLSPAQQAALGLL 111
>sp|O61967|LAP1_CAEEL Lap1 protein (Lethal protein 413) Length = 699 Score = 33.9 bits (76), Expect = 0.42 Identities = 24/71 (33%), Positives = 34/71 (47%) Frame = +3 Query: 387 VDRVDASSVAFSCGLREGDELLQIDHITKETFSGLQAVMELFRSRANKTVLVCVKRGNKR 566 V +V S A+ CGLREGD+L++ + + S A ME + R LV ++R Sbjct: 603 VTKVTPGSAAYRCGLREGDKLIRANDVNMINASQDNA-MEAIKKR-ETVELVVLRRSPSP 660 Query: 567 VHLTIVPPSQG 599 V T P G Sbjct: 661 VSRTSEPSLNG 671
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,105,054 Number of Sequences: 369166 Number of extensions: 1571551 Number of successful extensions: 4204 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4081 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4200 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 5927776870 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)