Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_010_M18 (471 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q13283|G3BP_HUMAN Ras-GTPase-activating protein binding ... 61 1e-09 sp|P97855|G3BP_MOUSE Ras-GTPase-activating protein binding ... 60 2e-09 sp|P97379|G3B2_MOUSE Ras-GTPase-activating protein binding ... 54 2e-07 sp|Q9UN86|G3B2_HUMAN Ras-GTPase-activating protein binding ... 54 2e-07 sp|Q13148|TADBP_HUMAN TAR DNA-binding protein 43 (TDP-43) 44 1e-04 sp|Q96EP5|DAZP1_HUMAN DAZ-associated protein 1 (Deleted in ... 39 0.008 sp|Q9JII5|DAZP1_MOUSE DAZ-associated protein 1 (Deleted in ... 39 0.008 sp|Q98SJ2|DAZP1_XENLA DAZ-associated protein 1 (Deleted in ... 39 0.008 sp|P51968|RO31_XENLA Heterogeneous nuclear ribonucleoprotei... 37 0.030 sp|Q920Q6|MSI2H_MOUSE RNA-binding protein Musashi homolog 2... 37 0.030
>sp|Q13283|G3BP_HUMAN Ras-GTPase-activating protein binding protein 1 (GAP SH3-domain binding protein 1) (G3BP-1) (DNA helicase VIII) (HDH-VIII) Length = 466 Score = 61.2 bits (147), Expect = 1e-09 Identities = 37/83 (44%), Positives = 52/83 (62%), Gaps = 1/83 (1%) Frame = +3 Query: 12 EDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYYSAH 191 + ELKDFF + YG V ++RI N G LPNFGF+VF + E V+++L N+PI + Sbjct: 353 KSELKDFF-QSYGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGE 405 Query: 192 -RLNVEQKMGSSRGSHKAGRR*N 257 RLNVE+K +R + + RR N Sbjct: 406 VRLNVEEK--KTRAAREGDRRDN 426
>sp|P97855|G3BP_MOUSE Ras-GTPase-activating protein binding protein 1 (GAP SH3-domain binding protein 1) (G3BP-1) (DNA helicase VIII) (HDH-VIII) Length = 465 Score = 60.5 bits (145), Expect = 2e-09 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 1/83 (1%) Frame = +3 Query: 12 EDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYY-SA 188 + ELKDFF + +G V ++RI N G LPNFGF+VF + E V+++L N+PI + A Sbjct: 351 KSELKDFF-QNFGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGA 403 Query: 189 HRLNVEQKMGSSRGSHKAGRR*N 257 RLNVE+K +R + + RR N Sbjct: 404 VRLNVEEK--KTRAAREGDRRDN 424
>sp|P97379|G3B2_MOUSE Ras-GTPase-activating protein binding protein 2 (GAP SH3-domain binding protein 2) (G3BP-2) Length = 482 Score = 53.9 bits (128), Expect = 2e-07 Identities = 33/71 (46%), Positives = 45/71 (63%), Gaps = 1/71 (1%) Frame = +3 Query: 3 NMTEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYY 182 ++ E+ELK+FF +G V ++RI T G LPNFGF+VF + E V+ IL KPI + Sbjct: 341 DIDENELKEFFMS-FGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMF 396 Query: 183 SAH-RLNVEQK 212 RLNVE+K Sbjct: 397 RGEVRLNVEEK 407
>sp|Q9UN86|G3B2_HUMAN Ras-GTPase-activating protein binding protein 2 (GAP SH3-domain binding protein 2) (G3BP-2) Length = 482 Score = 53.9 bits (128), Expect = 2e-07 Identities = 33/71 (46%), Positives = 45/71 (63%), Gaps = 1/71 (1%) Frame = +3 Query: 3 NMTEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYY 182 ++ E+ELK+FF +G V ++RI T G LPNFGF+VF + E V+ IL KPI + Sbjct: 341 DIDENELKEFFMS-FGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMF 396 Query: 183 SAH-RLNVEQK 212 RLNVE+K Sbjct: 397 RGEVRLNVEEK 407
>sp|Q13148|TADBP_HUMAN TAR DNA-binding protein 43 (TDP-43) Length = 414 Score = 44.3 bits (103), Expect = 1e-04 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 2/84 (2%) Frame = +3 Query: 3 NMTEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIY- 179 +MTEDEL++FFS+ YG V DV I KP F F+ F + ++ + + I Sbjct: 201 DMTEDELREFFSQ-YGDVMDVFIP--------KPFRAFAFVTFADDQIAQSLCGEDLIIK 251 Query: 180 -YSAHRLNVEQKMGSSRGSHKAGR 248 S H N E K S+R ++GR Sbjct: 252 GISVHISNAEPKHNSNRQLERSGR 275
>sp|Q96EP5|DAZP1_HUMAN DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1) Length = 407 Score = 38.5 bits (88), Expect = 0.008 Identities = 23/74 (31%), Positives = 42/74 (56%) Frame = +3 Query: 9 TEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYYSA 188 T++ L+ +FS+ YG V D I K +T+N+ + FGF+ F + V +L ++P ++ Sbjct: 22 TQETLRSYFSQ-YGEVVDCVIMKDKTTNQSR---GFGFVKFKDPNCVGTVLASRP--HTL 75 Query: 189 HRLNVEQKMGSSRG 230 N++ K + RG Sbjct: 76 DGRNIDPKPCTPRG 89
>sp|Q9JII5|DAZP1_MOUSE DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1) Length = 406 Score = 38.5 bits (88), Expect = 0.008 Identities = 23/74 (31%), Positives = 42/74 (56%) Frame = +3 Query: 9 TEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYYSA 188 T++ L+ +FS+ YG V D I K +T+N+ + FGF+ F + V +L ++P ++ Sbjct: 22 TQETLRSYFSQ-YGEVVDCVIMKDKTTNQSR---GFGFVKFKDPNCVGTVLASRP--HTL 75 Query: 189 HRLNVEQKMGSSRG 230 N++ K + RG Sbjct: 76 DGRNIDPKPCTPRG 89
>sp|Q98SJ2|DAZP1_XENLA DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1) (Proline-rich Vg1 mRNA-binding protein) Length = 360 Score = 38.5 bits (88), Expect = 0.008 Identities = 23/74 (31%), Positives = 42/74 (56%) Frame = +3 Query: 9 TEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYYSA 188 T++ L+ +FS+ YG V D I K +T+N+ + FGF+ F + V +L ++P ++ Sbjct: 22 TQETLRSYFSQ-YGEVVDCVIMKDKTTNQSR---GFGFVKFKDPNCVGTVLASRP--HTL 75 Query: 189 HRLNVEQKMGSSRG 230 N++ K + RG Sbjct: 76 DGRNIDPKPCTPRG 89
>sp|P51968|RO31_XENLA Heterogeneous nuclear ribonucleoprotein A3 homolog 1 (hnRNP A3(A)) Length = 373 Score = 36.6 bits (83), Expect = 0.030 Identities = 21/72 (29%), Positives = 40/72 (55%) Frame = +3 Query: 12 EDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYYSAH 191 E L+D+ SE YG ++ + + + R S + + F F+ F +H+ V++I+ K Y++ + Sbjct: 131 EYHLRDY-SESYGKIETIEVMEDRQSGKKR---GFAFVTFDDHDTVDKIVVQK--YHTIN 184 Query: 192 RLNVEQKMGSSR 227 N E K S+ Sbjct: 185 GHNCEVKKALSK 196
>sp|Q920Q6|MSI2H_MOUSE RNA-binding protein Musashi homolog 2 (Musashi-2) Length = 346 Score = 36.6 bits (83), Expect = 0.030 Identities = 17/52 (32%), Positives = 32/52 (61%) Frame = +3 Query: 3 NMTEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEI 158 N +++K +F E++G V+D + +T+N + FGF+ F N +VVE++ Sbjct: 120 NTVVEDVKQYF-EQFGKVEDAMLMFDKTTNRHR---GFGFVTFENEDVVEKV 167
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,229,450 Number of Sequences: 369166 Number of extensions: 970733 Number of successful extensions: 2065 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2027 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2064 length of database: 68,354,980 effective HSP length: 101 effective length of database: 49,696,745 effective search space used: 2733320975 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)