Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_M16
(499 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9R0P6|SPC18_MOUSE Microsomal signal peptidase 18 kDa su... 238 6e-63
sp|Q9BY50|SPC21_HUMAN Microsomal signal peptidase 21 kDa su... 237 1e-62
sp|Q9D8V7|SPC21_MOUSE Microsomal signal peptidase 21 kDa su... 237 1e-62
sp|P13679|SPC21_CANFA Microsomal signal peptidase 21 kDa su... 237 1e-62
sp|P67812|SPC18_HUMAN Microsomal signal peptidase 18 kDa su... 236 2e-62
sp|Q9WTR7|SPC21_RAT Microsomal signal peptidase 21 kDa subu... 236 2e-62
sp|P42667|SPC18_RAT Microsomal signal peptidase 18 kDa subu... 235 5e-62
sp|P15367|SEC11_YEAST Signal sequence processing protein SEC11 130 2e-30
sp|P54506|LEPW_BACSU Signal peptidase I W (SPase I) (Leader... 50 2e-06
sp|P37675|YIAN_ECOLI Hypothetical protein yiaN 32 0.83
>sp|Q9R0P6|SPC18_MOUSE Microsomal signal peptidase 18 kDa subunit (SPase 18 kDa subunit)
(SPC18) (Endopeptidase SP18) (SEC11-like 1) (Sid 2895)
Length = 179
Score = 238 bits (607), Expect = 6e-63
Identities = 111/140 (79%), Positives = 131/140 (93%)
Frame = +2
Query: 2 IVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVI 181
+V+TGSESPIVVVLSGSMEPAF RGDLLFLTN ++PIRVG+I+VFRI+GREIPIVHRV+
Sbjct: 40 MVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVL 99
Query: 182 KVHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGFMPYIGMVTIIMNDY 361
K+HEK+DG IKFLTKGDNN+VDDRGLY + Q+WLE+KDV+GRA+GF+PYIG+VTI+MNDY
Sbjct: 100 KIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDY 159
Query: 362 PKFKYAMLGCLGLFVLAHRE 421
PKFKYA+L LGLFVL HRE
Sbjct: 160 PKFKYAVLFLLGLFVLVHRE 179
>sp|Q9BY50|SPC21_HUMAN Microsomal signal peptidase 21 kDa subunit (SPase 21 kDa subunit)
(SPC21) (SEC11-like 3)
sp|Q5RC30|SPC21_PONPY Microsomal signal peptidase 21 kDa subunit (SPase 21 kDa subunit)
(SPC21) (SEC11-like 3)
Length = 192
Score = 237 bits (605), Expect = 1e-62
Identities = 110/141 (78%), Positives = 129/141 (91%)
Frame = +2
Query: 2 IVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVI 181
IV+TGSESPIVVVLSGSMEPAF RGDLLFLTNFR++PIR G+I+VF+++GR+IPIVHRVI
Sbjct: 52 IVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVI 111
Query: 182 KVHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGFMPYIGMVTIIMNDY 361
KVHEK++G IKFLTKGDNN VDDRGLY E Q WLE+KDV+GRA+GF+PY+GMVTIIMNDY
Sbjct: 112 KVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDY 171
Query: 362 PKFKYAMLGCLGLFVLAHRES 424
PKFKYA+L +G +VL RES
Sbjct: 172 PKFKYALLAVMGAYVLLKRES 192
>sp|Q9D8V7|SPC21_MOUSE Microsomal signal peptidase 21 kDa subunit (SPase 21 kDa subunit)
(SPC21) (SEC11-like 3)
Length = 192
Score = 237 bits (605), Expect = 1e-62
Identities = 110/141 (78%), Positives = 129/141 (91%)
Frame = +2
Query: 2 IVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVI 181
IV+TGSESPIVVVLSGSMEPAF RGDLLFLTNFR++PIR G+I+VF+++GR+IPIVHRVI
Sbjct: 52 IVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVI 111
Query: 182 KVHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGFMPYIGMVTIIMNDY 361
KVHEK++G IKFLTKGDNN VDDRGLY E Q WLE+KDV+GRA+GF+PY+GMVTIIMNDY
Sbjct: 112 KVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDY 171
Query: 362 PKFKYAMLGCLGLFVLAHRES 424
PKFKYA+L +G +VL RES
Sbjct: 172 PKFKYALLAVMGAYVLLKRES 192
>sp|P13679|SPC21_CANFA Microsomal signal peptidase 21 kDa subunit (SPase 21 kDa subunit)
(SPC21) (SEC11-like 3)
Length = 192
Score = 237 bits (605), Expect = 1e-62
Identities = 110/141 (78%), Positives = 129/141 (91%)
Frame = +2
Query: 2 IVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVI 181
IV+TGSESPIVVVLSGSMEPAF RGDLLFLTNFR++PIR G+I+VF+++GR+IPIVHRVI
Sbjct: 52 IVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVI 111
Query: 182 KVHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGFMPYIGMVTIIMNDY 361
KVHEK++G IKFLTKGDNN VDDRGLY E Q WLE+KDV+GRA+GF+PY+GMVTIIMNDY
Sbjct: 112 KVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDY 171
Query: 362 PKFKYAMLGCLGLFVLAHRES 424
PKFKYA+L +G +VL RES
Sbjct: 172 PKFKYALLAVMGAYVLLKRES 192
>sp|P67812|SPC18_HUMAN Microsomal signal peptidase 18 kDa subunit (SPase 18 kDa subunit)
(SPC18) (Endopeptidase SP18) (SEC11-like 1)
sp|P67811|SPC18_CANFA Microsomal signal peptidase 18 kDa subunit (SPase 18 kDa subunit)
(SPC18) (Endopeptidase SP18) (SEC11-like 1)
sp|P67810|SPC18_BOVIN Microsomal signal peptidase 18 kDa subunit (SPase 18 kDa subunit)
(SPC18) (Endopeptidase SP18) (SEC11-like 1)
sp|Q5R9C7|SPC18_PONPY Microsomal signal peptidase 18 kDa subunit (SPase 18 kDa subunit)
(SPC18) (Endopeptidase SP18) (SEC11-like 1)
Length = 179
Score = 236 bits (602), Expect = 2e-62
Identities = 110/140 (78%), Positives = 131/140 (93%)
Frame = +2
Query: 2 IVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVI 181
+V+TGSESPIVVVLSGSMEPAF RGDLLFLTN ++PIRVG+I+VFRI+GREIPIVHRV+
Sbjct: 40 MVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVL 99
Query: 182 KVHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGFMPYIGMVTIIMNDY 361
K+HEK++G IKFLTKGDNN+VDDRGLY + Q+WLE+KDV+GRA+GF+PYIG+VTI+MNDY
Sbjct: 100 KIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDY 159
Query: 362 PKFKYAMLGCLGLFVLAHRE 421
PKFKYA+L LGLFVL HRE
Sbjct: 160 PKFKYAVLFLLGLFVLVHRE 179
>sp|Q9WTR7|SPC21_RAT Microsomal signal peptidase 21 kDa subunit (SPase 21 kDa subunit)
(SPC21) (SEC11-like 3)
Length = 192
Score = 236 bits (602), Expect = 2e-62
Identities = 109/141 (77%), Positives = 129/141 (91%)
Frame = +2
Query: 2 IVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVI 181
IV+TGSESPIVVVLSGSMEPAF RGDLLFLTNFR++PIR G+I+VF+++GR+IPIVHRVI
Sbjct: 52 IVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVI 111
Query: 182 KVHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGFMPYIGMVTIIMNDY 361
KVHEK++G IKFLTKGDNN VDDRGLY E Q WLE+KDV+GRA+GF+PY+GMVTIIMNDY
Sbjct: 112 KVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDY 171
Query: 362 PKFKYAMLGCLGLFVLAHRES 424
PKFKYA++ +G +VL RES
Sbjct: 172 PKFKYALVAVMGAYVLLKRES 192
>sp|P42667|SPC18_RAT Microsomal signal peptidase 18 kDa subunit (SPase 18 kDa subunit)
(SPC18) (Endopeptidase SP18) (SEC11-like 1)
Length = 179
Score = 235 bits (599), Expect = 5e-62
Identities = 109/140 (77%), Positives = 130/140 (92%)
Frame = +2
Query: 2 IVVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVI 181
+++TGSESPIVVVLSGSMEPAF RGDLLFLTN ++PIRVG+I+VFRI+GREIPIVHRV+
Sbjct: 40 MLITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVL 99
Query: 182 KVHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGFMPYIGMVTIIMNDY 361
K+HEK+DG IKFLTKGDNN+VDDRGLY + Q+WLE+KDV+GRA+GF+PYIG+VTI+MNDY
Sbjct: 100 KIHEKQDGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDY 159
Query: 362 PKFKYAMLGCLGLFVLAHRE 421
PKF YA+L LGLFVL HRE
Sbjct: 160 PKFSYAVLFLLGLFVLVHRE 179
>sp|P15367|SEC11_YEAST Signal sequence processing protein SEC11
Length = 167
Score = 130 bits (326), Expect = 2e-30
Identities = 66/136 (48%), Positives = 95/136 (69%), Gaps = 1/136 (0%)
Frame = +2
Query: 5 VVTGSESPIVVVLSGSMEPAFFRGDLLFLTNFRDEPIRVGDIIVFRIDGREIPIVHRVIK 184
+ T S SPIVVVLSGSMEPAF RGD+LFL N R+ +VGD++V+ ++G++IPIVHRV++
Sbjct: 29 IATNSASPIVVVLSGSMEPAFQRGDILFLWN-RNTFNQVGDVVVYEVEGKQIPIVHRVLR 87
Query: 185 VHEKEDGSIKFLTKGDNNSVDDRGLYAENQYWLER-KDVIGRAKGFMPYIGMVTIIMNDY 361
H LTKGDNN+ +D LYA + +L + K+++G KG+ P +G +TI +++
Sbjct: 88 QHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISEN 147
Query: 362 PKFKYAMLGCLGLFVL 409
K+A+LG LGL L
Sbjct: 148 KYAKFALLGMLGLSAL 163
>sp|P54506|LEPW_BACSU Signal peptidase I W (SPase I) (Leader peptidase I)
Length = 190
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Frame = +2
Query: 38 VLSGSMEPAFFRGDLLFLTNFRD-EPIRVGDIIVFRIDGREIPIVHRVIKVHEKEDGSIK 214
VLSGSMEP F G L+ + D + ++ GD+I F D + HR++ + K+ +
Sbjct: 43 VLSGSMEPEFNTGSLILVKEITDVKELQKGDVITFMQDA-NTAVTHRIVDI-TKQGDHLL 100
Query: 215 FLTKGDNNSVDDRGLYAENQYWLERKDVIGRAKGF-MPYIG 334
F TKGDNN+ D ++ ++V + GF +PY G
Sbjct: 101 FKTKGDNNAAADSAPVSD-------ENVRAQYTGFQLPYAG 134
>sp|P37675|YIAN_ECOLI Hypothetical protein yiaN
Length = 425
Score = 32.0 bits (71), Expect = 0.83
Identities = 18/39 (46%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Frame = -2
Query: 243 TELLSPLVKNL-IDPSSFS*TFITRCTIGISLPSILNTI 130
T +L PLVK IDP F FI C+IG+ P I N +
Sbjct: 340 TPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVL 378
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,696,922
Number of Sequences: 369166
Number of extensions: 1168765
Number of successful extensions: 2918
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2856
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2914
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3119256630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)