Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_K19
(328 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein) 100 2e-21
sp|O35186|CATK_RAT Cathepsin K precursor 99 2e-21
sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor 99 4e-21
sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (C... 99 4e-21
sp|P61277|CATK_MACMU Cathepsin K precursor >gi|47117667|sp|... 99 4e-21
sp|P55097|CATK_MOUSE Cathepsin K precursor 98 5e-21
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 98 7e-21
sp|Q9GLE3|CATK_PIG Cathepsin K precursor 98 7e-21
sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (C... 97 9e-21
sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor 97 1e-20
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
Length = 329
Score = 99.8 bits (247), Expect = 2e-21
Identities = 41/69 (59%), Positives = 52/69 (75%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y G+Y D +CSS+NVNHAVL +GYG + G WIIKNSWG WG KGY+ ++R+ NN C
Sbjct: 259 YSKGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIKNSWGESWGNKGYILMARNKNNAC 318
Query: 185 GIASMASVP 211
GIA++AS P
Sbjct: 319 GIANLASFP 327
>sp|O35186|CATK_RAT Cathepsin K precursor
Length = 329
Score = 99.4 bits (246), Expect = 2e-21
Identities = 40/69 (57%), Positives = 51/69 (73%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y G+Y D +C +NVNHAVLV+GYG + G +WIIKNSWG WG KGY+ L+R+ NN C
Sbjct: 259 YSRGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGESWGNKGYVLLARNKNNAC 318
Query: 185 GIASMASVP 211
GI ++AS P
Sbjct: 319 GITNLASFP 327
>sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor
Length = 326
Score = 98.6 bits (244), Expect = 4e-21
Identities = 37/73 (50%), Positives = 57/73 (78%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y++GIY +CS VNHAVL +GYG + G +WI+KNSWG+ WG +GY++++R+ N+C
Sbjct: 252 YRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMC 311
Query: 185 GIASMASVPLLKK 223
GIAS+AS+P++ +
Sbjct: 312 GIASLASLPMVAR 324
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
Length = 329
Score = 98.6 bits (244), Expect = 4e-21
Identities = 40/69 (57%), Positives = 52/69 (75%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y G+Y D SC+S+N+NHAVL +GYG + G WIIKNSWG WG KGY+ ++R+ NN C
Sbjct: 259 YSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNAC 318
Query: 185 GIASMASVP 211
GIA++AS P
Sbjct: 319 GIANLASFP 327
>sp|P61277|CATK_MACMU Cathepsin K precursor
sp|P61276|CATK_MACFA Cathepsin K precursor
Length = 329
Score = 98.6 bits (244), Expect = 4e-21
Identities = 40/69 (57%), Positives = 52/69 (75%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y G+Y D SC+S+N+NHAVL +GYG + G WIIKNSWG WG KGY+ ++R+ NN C
Sbjct: 259 YSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNAC 318
Query: 185 GIASMASVP 211
GIA++AS P
Sbjct: 319 GIANLASFP 327
>sp|P55097|CATK_MOUSE Cathepsin K precursor
Length = 329
Score = 98.2 bits (243), Expect = 5e-21
Identities = 41/69 (59%), Positives = 49/69 (71%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y G+Y D +C +NVNHAVLV+GYG + G WIIKNSWG WG KGY L+R+ NN C
Sbjct: 259 YSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKNNAC 318
Query: 185 GIASMASVP 211
GI +MAS P
Sbjct: 319 GITNMASFP 327
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 97.8 bits (242), Expect = 7e-21
Identities = 39/71 (54%), Positives = 55/71 (77%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y +G+Y + SCS + ++HAVL +GYG E GQ FW++KNSW + WG GY+K+SR+ NN C
Sbjct: 253 YSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNC 312
Query: 185 GIASMASVPLL 217
GIA++AS PL+
Sbjct: 313 GIATVASYPLV 323
>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
Length = 330
Score = 97.8 bits (242), Expect = 7e-21
Identities = 39/69 (56%), Positives = 53/69 (76%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEESGQSFWIIKNSWGSKWGMKGYMKLSRDTNNLC 184
Y G+Y D +C+S+N+NHAVL +GYG + G+ WIIKNSWG WG KGY+ ++R+ NN C
Sbjct: 260 YSKGVYYDENCNSDNLNHAVLAVGYGIQKGKKHWIIKNSWGENWGNKGYILMARNKNNAC 319
Query: 185 GIASMASVP 211
GIA++AS P
Sbjct: 320 GIANLASFP 328
>sp|Q9R014|CATJ_MOUSE Cathepsin J precursor (Cathepsin P) (Catlrp-p)
Length = 333
Score = 97.4 bits (241), Expect = 9e-21
Identities = 43/73 (58%), Positives = 55/73 (75%), Gaps = 4/73 (5%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYGEES----GQSFWIIKNSWGSKWGMKGYMKLSRDT 172
Y GIY + +CSS VNHAVLV+GYG E G ++W+IKNSWG +WGM GYM++++D
Sbjct: 258 YNGGIYYEPNCSSYFVNHAVLVVGYGSEGDVKDGNNYWLIKNSWGEEWGMNGYMQIAKDH 317
Query: 173 NNLCGIASMASVP 211
NN CGIAS+AS P
Sbjct: 318 NNHCGIASLASYP 330
>sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor
Length = 334
Score = 97.1 bits (240), Expect = 1e-20
Identities = 42/75 (56%), Positives = 54/75 (72%), Gaps = 4/75 (5%)
Frame = +2
Query: 5 YKTGIYDDTSCSSNNVNHAVLVIGYG----EESGQSFWIIKNSWGSKWGMKGYMKLSRDT 172
YK GIY + +CSS+ V H VLV+GYG E G +W+IKNSWG +WG++GYMKL++D
Sbjct: 260 YKGGIYHEPNCSSDTVTHGVLVVGYGFKGIETDGNHYWLIKNSWGKRWGIRGYMKLAKDK 319
Query: 173 NNLCGIASMASVPLL 217
NN CGIAS A P +
Sbjct: 320 NNHCGIASYAHYPTI 334
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,470,368
Number of Sequences: 369166
Number of extensions: 552415
Number of successful extensions: 1604
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1501
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1515
length of database: 68,354,980
effective HSP length: 77
effective length of database: 54,130,385
effective search space used: 1678041935
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)