Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_K12
(543 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9QXW9|LAT2_MOUSE Large neutral amino acids transporter ... 91 2e-18
sp|Q9UHI5|LAT2_HUMAN Large neutral amino acids transporter ... 91 2e-18
sp|Q9WVR6|LAT2_RAT Large neutral amino acids transporter sm... 91 2e-18
sp|Q9NS82|AAA1_HUMAN Asc-type amino acid transporter 1 (Asc-1) 75 8e-14
sp|P63116|AAA1_RAT Asc-type amino acid transporter 1 (Asc-1... 74 2e-13
sp|Q9UM01|YLA1_HUMAN Y+L amino acid transporter 1 (y(+)L-ty... 73 5e-13
sp|Q63016|LAT1_RAT Large neutral amino acids transporter sm... 72 9e-13
sp|Q01650|LAT1_HUMAN Large neutral amino acids transporter ... 72 1e-12
sp|Q9Z127|LAT1_MOUSE Large neutral amino acids transporter ... 72 1e-12
sp|Q9UPY5|XCT_HUMAN Cystine/glutamate transporter (Amino ac... 69 1e-11
>sp|Q9QXW9|LAT2_MOUSE Large neutral amino acids transporter small subunit 2 (L-type amino
acid transporter 2)
Length = 531
Score = 90.9 bits (224), Expect = 2e-18
Identities = 44/99 (44%), Positives = 60/99 (60%)
Frame = +3
Query: 234 LAQKLIEMTVAIRLYGVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILET 413
LA + +T +L GVM WIMPI VA+STFGGVNG+L +SR+FF A+E +P +L
Sbjct: 296 LASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM 355
Query: 414 INIKYYTPVPXXXXXXXXXXXXXXXXDINILINYMGFVN 530
I++K TP+P D+ LINY+GF+N
Sbjct: 356 IHVKRCTPIPALLFTCLSTLLMLVTSDMYTLINYVGFIN 394
>sp|Q9UHI5|LAT2_HUMAN Large neutral amino acids transporter small subunit 2 (L-type amino
acid transporter 2) (hLAT2)
Length = 535
Score = 90.9 bits (224), Expect = 2e-18
Identities = 44/99 (44%), Positives = 60/99 (60%)
Frame = +3
Query: 234 LAQKLIEMTVAIRLYGVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILET 413
LA + +T +L GVM WIMPI VA+STFGGVNG+L +SR+FF A+E +P +L
Sbjct: 297 LASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM 356
Query: 414 INIKYYTPVPXXXXXXXXXXXXXXXXDINILINYMGFVN 530
I++K TP+P D+ LINY+GF+N
Sbjct: 357 IHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFIN 395
>sp|Q9WVR6|LAT2_RAT Large neutral amino acids transporter small subunit 2 (L-type amino
acid transporter 2)
Length = 533
Score = 90.9 bits (224), Expect = 2e-18
Identities = 44/99 (44%), Positives = 60/99 (60%)
Frame = +3
Query: 234 LAQKLIEMTVAIRLYGVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILET 413
LA + +T +L GVM WIMPI VA+STFGGVNG+L +SR+FF A+E +P +L
Sbjct: 298 LASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM 357
Query: 414 INIKYYTPVPXXXXXXXXXXXXXXXXDINILINYMGFVN 530
I++K TP+P D+ LINY+GF+N
Sbjct: 358 IHVKRCTPIPALLFTCLSTLLMLVTSDMYTLINYVGFIN 396
>sp|Q9NS82|AAA1_HUMAN Asc-type amino acid transporter 1 (Asc-1)
Length = 523
Score = 75.5 bits (184), Expect = 8e-14
Identities = 35/99 (35%), Positives = 54/99 (54%)
Frame = +3
Query: 234 LAQKLIEMTVAIRLYGVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILET 413
L+ + +T +L G W+MP+ VA+STFGG+NG L SR+ F A+E +P +L
Sbjct: 297 LSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAM 356
Query: 414 INIKYYTPVPXXXXXXXXXXXXXXXXDINILINYMGFVN 530
I++++ TP+P D LINY+ F+N
Sbjct: 357 IHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFIN 395
>sp|P63116|AAA1_RAT Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter)
sp|P63115|AAA1_MOUSE Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter)
Length = 530
Score = 74.3 bits (181), Expect = 2e-13
Identities = 35/99 (35%), Positives = 53/99 (53%)
Frame = +3
Query: 234 LAQKLIEMTVAIRLYGVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILET 413
L+ + +T +L G W+MP+ VA+STFGG+NG L +SR+ F A+E +P L
Sbjct: 303 LSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAM 362
Query: 414 INIKYYTPVPXXXXXXXXXXXXXXXXDINILINYMGFVN 530
I+++ TP+P D LINY+ F+N
Sbjct: 363 IHVRRCTPIPALLVCCGATAVIMLVGDTYTLINYVSFIN 401
>sp|Q9UM01|YLA1_HUMAN Y+L amino acid transporter 1 (y(+)L-type amino acid transporter 1)
(y+LAT-1) (Y+LAT1) (Monocyte amino acid permease 2)
(MOP-2)
Length = 511
Score = 72.8 bits (177), Expect = 5e-13
Identities = 35/97 (36%), Positives = 57/97 (58%)
Frame = +3
Query: 234 LAQKLIEMTVAIRLYGVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILET 413
LA + +T A +++G+ WI+P+ VA+S FGG+N +++A SR+FFV ++E +P +
Sbjct: 291 LASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICM 350
Query: 414 INIKYYTPVPXXXXXXXXXXXXXXXXDINILINYMGF 524
I+++ +TPVP DI LINY F
Sbjct: 351 IHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSF 387
>sp|Q63016|LAT1_RAT Large neutral amino acids transporter small subunit 1 (L-type amino
acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC)
(Integral membrane protein E16) (TA1 protein)
Length = 512
Score = 72.0 bits (175), Expect = 9e-13
Identities = 35/84 (41%), Positives = 48/84 (57%)
Frame = +3
Query: 279 GVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILETINIKYYTPVPXXXXX 458
GVM WI+P+FV +S FG VNG+L +SR+FFV ++E +P IL I+ + TPVP
Sbjct: 326 GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFT 385
Query: 459 XXXXXXXXXXXDINILINYMGFVN 530
DI +IN+ F N
Sbjct: 386 CVMTLMYAFSRDIFSIINFFSFFN 409
>sp|Q01650|LAT1_HUMAN Large neutral amino acids transporter small subunit 1 (L-type amino
acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC)
(CD98 light chain) (Integral membrane protein E16)
(hLAT1)
Length = 507
Score = 71.6 bits (174), Expect = 1e-12
Identities = 35/84 (41%), Positives = 48/84 (57%)
Frame = +3
Query: 279 GVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILETINIKYYTPVPXXXXX 458
GVM WI+P+FV +S FG VNG+L +SR+FFV ++E +P IL I+ + TPVP
Sbjct: 321 GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFT 380
Query: 459 XXXXXXXXXXXDINILINYMGFVN 530
DI +IN+ F N
Sbjct: 381 CVMTLLYAFSKDIFSVINFFSFFN 404
>sp|Q9Z127|LAT1_MOUSE Large neutral amino acids transporter small subunit 1 (L-type amino
acid transporter 1) (4F2 light chain) (4F2 LC) (4F2LC)
Length = 512
Score = 71.6 bits (174), Expect = 1e-12
Identities = 34/84 (40%), Positives = 48/84 (57%)
Frame = +3
Query: 279 GVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILETINIKYYTPVPXXXXX 458
GVM WI+P+FV +S FG VNG+L +SR+FFV ++E +P +L I+ + TPVP
Sbjct: 326 GVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSVLSMIHPQLLTPVPSLVFT 385
Query: 459 XXXXXXXXXXXDINILINYMGFVN 530
DI +IN+ F N
Sbjct: 386 CIMTLMYAFSRDIFSIINFFSFFN 409
>sp|Q9UPY5|XCT_HUMAN Cystine/glutamate transporter (Amino acid transport system xc-)
(xCT) (Calcium channel blocker resistance protein CCBR1)
Length = 501
Score = 68.6 bits (166), Expect = 1e-11
Identities = 33/97 (34%), Positives = 55/97 (56%)
Frame = +3
Query: 234 LAQKLIEMTVAIRLYGVMWWIMPIFVAMSTFGGVNGNLLATSRIFFVAAQENQMPMILET 413
L + +T + RL G +PIFVA+S FG +NG + A SR+F+VA++E +P IL
Sbjct: 298 LLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHLPEILSM 357
Query: 414 INIKYYTPVPXXXXXXXXXXXXXXXXDINILINYMGF 524
I+++ +TP+P D++ L+N++ F
Sbjct: 358 IHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSF 394
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,078,765
Number of Sequences: 369166
Number of extensions: 1172152
Number of successful extensions: 3033
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2990
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3030
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3734833040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)