Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_K03
(383 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Int... 50 2e-06
sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6 50 2e-06
sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cys... 45 4e-05
sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cys... 44 1e-04
sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1 40 0.002
sp|Q13077|TRAF1_HUMAN TNF receptor-associated factor 1 (Eps... 40 0.002
sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tum... 37 0.018
sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RIN... 35 0.053
sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2 35 0.069
sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD4... 33 0.26
>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer)
(RING finger protein 85)
Length = 522
Score = 50.1 bits (118), Expect = 2e-06
Identities = 23/61 (37%), Positives = 39/61 (63%), Gaps = 2/61 (3%)
Frame = +1
Query: 40 SPAFYTHENGYRIQMRL-LPVYERARCSG-VMIYPNCIQGNYDGYLDWPLEAEISISVVD 213
SP FYT + GY++ MRL L + RC+ + ++ + +QG YD +L WP + I ++++D
Sbjct: 377 SPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILD 436
Query: 214 Q 216
Q
Sbjct: 437 Q 437
>sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6
Length = 530
Score = 50.1 bits (118), Expect = 2e-06
Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Frame = +1
Query: 19 KRKSFYESPAFYTHENGYRIQMRL-LPVYERARCSG-VMIYPNCIQGNYDGYLDWPLEAE 192
+R SP FYT GY++ MRL L + RC+ + ++ + +QG YD +L WP +
Sbjct: 378 ERPVVIHSPGFYTGRPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGT 437
Query: 193 ISISVVDQ 216
I ++++DQ
Sbjct: 438 IRLTILDQ 445
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cysteine-rich motif associated to
RING and Traf domains protein 1)
Length = 470
Score = 45.4 bits (106), Expect = 4e-05
Identities = 22/60 (36%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Frame = +1
Query: 40 SPAFYTHENGYRIQMRL-LPVYERARCSGVMIYPNCIQGNYDGYLDWPLEAEISISVVDQ 216
SPAFYTH+ GY++Q+ L + + IY + G +D L+WPL ++ S++DQ
Sbjct: 334 SPAFYTHKYGYKLQVSASLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPLARRVTFSLLDQ 393
>sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cysteine-rich domain associated
with RING and Traf domains protein 1) (Malignant 62)
(RING finger protein 83)
Length = 470
Score = 43.5 bits (101), Expect = 1e-04
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = +1
Query: 40 SPAFYTHENGYRIQM-RLLPVYERARCSGVMIYPNCIQGNYDGYLDWPLEAEISISVVDQ 216
SPAFYTH+ GY++Q+ L + + +Y + G +D L+WP ++ S++DQ
Sbjct: 334 SPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQ 393
>sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1
Length = 409
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Frame = +1
Query: 13 CNKRKSFYESPAFYTHENGYRIQMRLLPVYERARCSG----VMIYPNCIQGNYDGYLDWP 180
C + S + SPAFYT + GY++ +RL Y SG + ++ ++G YD L WP
Sbjct: 278 CGRTVSLF-SPAFYTAKYGYKLCLRL---YLNGDGSGKKTHLSLFIVIMRGEYDALLPWP 333
Query: 181 LEAEISISVVDQ 216
+++ ++DQ
Sbjct: 334 FRNKVTFMLLDQ 345
>sp|Q13077|TRAF1_HUMAN TNF receptor-associated factor 1 (Epstein-Barr virus-induced
protein 6)
Length = 416
Score = 39.7 bits (91), Expect = 0.002
Identities = 21/69 (30%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +1
Query: 13 CNKRKSFYESPAFYTHENGYRIQMRL-LPVYERARCSGVMIYPNCIQGNYDGYLDWPLEA 189
C + S + SPAFYT + GY++ +RL L + + + ++ ++G YD L WP
Sbjct: 285 CGRTVSLF-SPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRN 343
Query: 190 EISISVVDQ 216
+++ ++DQ
Sbjct: 344 KVTFMLLDQ 352
>sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tumor necrosis factor type 2
receptor-associated protein 3)
Length = 501
Score = 36.6 bits (83), Expect = 0.018
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 8/80 (10%)
Frame = +1
Query: 1 ISEFCNKRKSFYE-------SPAFYTHENGYRIQMRL-LPVYERARCSGVMIYPNCIQGN 156
IS+F KR+ SPAFYT GY++ +R+ L R + + ++ ++G
Sbjct: 358 ISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGP 417
Query: 157 YDGYLDWPLEAEISISVVDQ 216
D L WP ++++ ++DQ
Sbjct: 418 NDALLRWPFNQKVTLMLLDQ 437
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
Length = 557
Score = 35.0 bits (79), Expect = 0.053
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +1
Query: 40 SPAFYTHENGYRIQMRL-LPVYERARCSGVMIYPNCIQGNYDGYLDWPLEAEISISVVDQ 216
S +FYT GYR+ R L R S + +Y ++G +D L WP +++ ++DQ
Sbjct: 430 SQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ 489
>sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2
Length = 501
Score = 34.7 bits (78), Expect = 0.069
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 8/79 (10%)
Frame = +1
Query: 1 ISEFCNKRKSFYE-------SPAFYTHENGYRIQMRL-LPVYERARCSGVMIYPNCIQGN 156
IS+F KR+ SPAFYT GY++ +R+ L R + + ++ ++G
Sbjct: 358 ISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGP 417
Query: 157 YDGYLDWPLEAEISISVVD 213
D L WP ++++ ++D
Sbjct: 418 NDALLQWPFNQKVTLMLLD 436
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
associated protein) (LAP1) (CAP-1)
Length = 568
Score = 32.7 bits (73), Expect = 0.26
Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +1
Query: 19 KRKSFYESPAFYTHENGYRIQMRL-LPVYERARCSGVMIYPNCIQGNYDGYLDWPLEAEI 195
K S Y P FYT GY++ R+ L + + + ++ ++G YD L WP + ++
Sbjct: 436 KTLSLYSQP-FYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKV 494
Query: 196 SISVVDQ 216
++ ++DQ
Sbjct: 495 TLMLMDQ 501
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,775,201
Number of Sequences: 369166
Number of extensions: 867605
Number of successful extensions: 2130
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2083
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2123
length of database: 68,354,980
effective HSP length: 94
effective length of database: 50,989,890
effective search space used: 1682666370
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)