Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_J16
(509 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase) 190 1e-48
sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase) 190 1e-48
sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase) 189 2e-48
sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Hist... 188 7e-48
sp|Q8RBH4|HUTH_THETN Histidine ammonia-lyase (Histidase) 125 6e-29
sp|Q9HQD5|HUTH_HALSA Probable histidine ammonia-lyase (Hist... 125 8e-29
sp|Q7NCB3|HUTH_GLOVI Histidine ammonia-lyase (Histidase) 119 5e-27
sp|Q8RDU4|HUTH2_FUSNN Histidine ammonia-lyase 2 (Histidase 2) 115 5e-26
sp|Q93TX3|HUTH_STIAU Histidine ammonia-lyase (Histidase) 114 2e-25
sp|Q891Q1|HUTH_CLOTE Histidine ammonia-lyase (Histidase) 113 2e-25
>sp|P21213|HUTH_RAT Histidine ammonia-lyase (Histidase)
Length = 657
Score = 190 bits (483), Expect = 1e-48
Identities = 89/130 (68%), Positives = 108/130 (83%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
IARQAD++AALTLEVLKGTT+AFDT IH VRPH GQ++VA ++LL + +PSEI+ESH
Sbjct: 326 IARQADIVAALTLEVLKGTTKAFDTDIHAVRPHRGQIEVAFRFRSLLDSDHHPSEIAESH 385
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFH 362
RFC +VQDAYTLRCCPQVHG+V DT+ FV+ +ITTE+NS+TDNP+VF G IS GNFH
Sbjct: 386 RFCDRVQDAYTLRCCPQVHGVVNDTIAFVKDIITTELNSATDNPMVFASRGETISGGNFH 445
Query: 363 GEYTAKLLSF 392
GEY AK L +
Sbjct: 446 GEYPAKALDY 455
>sp|P35492|HUTH_MOUSE Histidine ammonia-lyase (Histidase)
Length = 657
Score = 190 bits (483), Expect = 1e-48
Identities = 89/130 (68%), Positives = 108/130 (83%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
IARQAD++AALTLEVLKGTT+AFDT IH VRPH GQ++VA ++LL + +PSEI+ESH
Sbjct: 326 IARQADIVAALTLEVLKGTTKAFDTDIHAVRPHRGQIEVAFRFRSLLDSDHHPSEIAESH 385
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFH 362
RFC +VQDAYTLRCCPQVHG+V DT+ FV+ +ITTE+NS+TDNP+VF G IS GNFH
Sbjct: 386 RFCDRVQDAYTLRCCPQVHGVVNDTIAFVKDIITTELNSATDNPMVFASRGETISGGNFH 445
Query: 363 GEYTAKLLSF 392
GEY AK L +
Sbjct: 446 GEYPAKALDY 455
>sp|P42357|HUTH_HUMAN Histidine ammonia-lyase (Histidase)
Length = 657
Score = 189 bits (481), Expect = 2e-48
Identities = 87/130 (66%), Positives = 109/130 (83%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
IARQAD++AALTLEVLKGTT+AFDT IH +RPH GQ++VA ++LL + +PSEI+ESH
Sbjct: 326 IARQADIVAALTLEVLKGTTKAFDTDIHALRPHRGQIEVAFRFRSLLDSDHHPSEIAESH 385
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFH 362
RFC +VQDAYTLRCCPQVHG+V DT+ FV+ +ITTE+NS+TDNP+VF + G +S GNFH
Sbjct: 386 RFCDRVQDAYTLRCCPQVHGVVNDTIAFVKNIITTELNSATDNPMVFANRGETVSGGNFH 445
Query: 363 GEYTAKLLSF 392
GEY AK L +
Sbjct: 446 GEYPAKALDY 455
>sp|Q20502|HUTH_CAEEL Probable histidine ammonia-lyase (Histidase)
Length = 677
Score = 188 bits (477), Expect = 7e-48
Identities = 93/130 (71%), Positives = 106/130 (81%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
IARQADVIAAL+L+VLKGTTRA+D IH +RPH GQ A L+ALLH+ PS+I+ESH
Sbjct: 342 IARQADVIAALSLDVLKGTTRAYDPDIHRIRPHRGQNLSALRLRALLHSEANPSQIAESH 401
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFH 362
R CTKVQDAYTLRC PQVHG+V DT++FVR +ITTEMNS+TDNPLVF D IIS GNFH
Sbjct: 402 RNCTKVQDAYTLRCVPQVHGVVHDTIEFVREIITTEMNSATDNPLVFADREEIISGGNFH 461
Query: 363 GEYTAKLLSF 392
GEY AK L F
Sbjct: 462 GEYPAKALDF 471
>sp|Q8RBH4|HUTH_THETN Histidine ammonia-lyase (Histidase)
Length = 508
Score = 125 bits (314), Expect = 6e-29
Identities = 63/142 (44%), Positives = 90/142 (63%)
Frame = +3
Query: 15 ADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESHRFCT 194
AD +A++TLE L+G AFD + VRPH GQ+ A++++ ++ S+ + E
Sbjct: 219 ADAVASITLEALRGIIDAFDDRVQMVRPHKGQIVSAKNVRKMVEGSELITRQGE-----I 273
Query: 195 KVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFHGEYT 374
+VQDAYTLRC PQVHG V D + ++ V+ E+NS+TDNPL+FPD G +IS GNFHGE
Sbjct: 274 RVQDAYTLRCIPQVHGAVRDAISYIERVLGVEINSATDNPLIFPDDGEVISGGNFHGEPV 333
Query: 375 AKLLSF*QCIMSVSMSESDRAI 440
A + F +S + S+R I
Sbjct: 334 ALAMDFLSIALSEIANISERRI 355
>sp|Q9HQD5|HUTH_HALSA Probable histidine ammonia-lyase (Histidase)
Length = 525
Score = 125 bits (313), Expect = 8e-29
Identities = 66/141 (46%), Positives = 82/141 (58%), Gaps = 11/141 (7%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
+ R AD ALT EV TT + IHEVRPH GQ ARH++ L S E+ + H
Sbjct: 217 VLRSADTAGALTTEVTMSTTASCAPAIHEVRPHDGQAVSARHIRNLTAGS----EVLDHH 272
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVF-----------PD 329
R C +VQDAY++RC PQVHG V D LD +R + TE+NS+TDNPLVF D
Sbjct: 273 RDCDRVQDAYSIRCLPQVHGAVRDALDHLRAAVATELNSATDNPLVFAGDRVGPRASGTD 332
Query: 330 SGMIISAGNFHGEYTAKLLSF 392
++S GNFHGE A L +
Sbjct: 333 RAAVVSGGNFHGEVLALRLGY 353
>sp|Q7NCB3|HUTH_GLOVI Histidine ammonia-lyase (Histidase)
Length = 514
Score = 119 bits (297), Expect = 5e-27
Identities = 58/125 (46%), Positives = 79/125 (63%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
+A+ AD+ A+TLE G+ AF H +RPH GQ AR+L L +S + SH
Sbjct: 219 LAKLADLACAMTLEATLGSRSAFLPHFHRLRPHPGQQSSARNLLVLTEDSA----LIASH 274
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFH 362
C +VQDAY+LRC PQVHG LD + + GVI E+NS TDNPL+F D+G +++ G+FH
Sbjct: 275 AGCDRVQDAYSLRCAPQVHGASLDAISYAAGVIAIEINSVTDNPLIFADTGQVVTGGHFH 334
Query: 363 GEYTA 377
G+ A
Sbjct: 335 GQPVA 339
>sp|Q8RDU4|HUTH2_FUSNN Histidine ammonia-lyase 2 (Histidase 2)
Length = 511
Score = 115 bits (289), Expect = 5e-26
Identities = 63/147 (42%), Positives = 91/147 (61%), Gaps = 1/147 (0%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
+ +QAD++A+L+++ L G AFD IH +RPH GQ+ A +L+ LL SK + E
Sbjct: 216 LLKQADIVASLSIDALGGIIDAFDERIHLIRPHKGQIYSAENLRKLLKGSKRTTRQGEK- 274
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFP-DSGMIISAGNF 359
++QDAY+LRC PQVHG D+V+ + TE+NS TDNPL+FP ++G IS GNF
Sbjct: 275 ----RMQDAYSLRCTPQVHGASRLAFDYVKQTVETEINSVTDNPLIFPGENGACISGGNF 330
Query: 360 HGEYTAKLLSF*QCIMSVSMSESDRAI 440
HG+ A + +MS + S+R I
Sbjct: 331 HGQPIAIAMDTLGILMSEIANISERRI 357
>sp|Q93TX3|HUTH_STIAU Histidine ammonia-lyase (Histidase)
Length = 510
Score = 114 bits (284), Expect = 2e-25
Identities = 59/122 (48%), Positives = 79/122 (64%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
+A AD+ A+TLE L G+ + F I +VR H GQ A HL+ LL +S + ESH
Sbjct: 217 LADLADLAGAMTLEGLLGSHKPFIPEIQDVRAHEGQKACAAHLRELLADSA----LVESH 272
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFH 362
C+KVQD Y+LRC PQVHG + L F R ++ E+NS+TDNPLVF ++ I+S GNFH
Sbjct: 273 VNCSKVQDPYSLRCMPQVHGAAREGLSFARRILEVEINSATDNPLVFVETERIVSGGNFH 332
Query: 363 GE 368
G+
Sbjct: 333 GQ 334
>sp|Q891Q1|HUTH_CLOTE Histidine ammonia-lyase (Histidase)
Length = 514
Score = 113 bits (283), Expect = 2e-25
Identities = 59/130 (45%), Positives = 81/130 (62%)
Frame = +3
Query: 3 IARQADVIAALTLEVLKGTTRAFDTVIHEVRPHSGQMKVARHLQALLHNSKYPSEISESH 182
+ + D+ AALT+E L+G AFD +H +R H GQM AR++ L+ S Y + E
Sbjct: 218 LLKVGDIAAALTIEALRGIKDAFDPRLHVIRAHEGQMATARNILKLIEGSTYVTRQGE-- 275
Query: 183 RFCTKVQDAYTLRCCPQVHGIVLDTLDFVRGVITTEMNSSTDNPLVFPDSGMIISAGNFH 362
+VQDAY+LRC PQ+HG DT+DFV+ + E+NS TDNP+V + G +IS GNFH
Sbjct: 276 ---LRVQDAYSLRCVPQIHGASKDTIDFVKEKVEIEINSVTDNPIVTRE-GDVISGGNFH 331
Query: 363 GEYTAKLLSF 392
GE A+ F
Sbjct: 332 GEPMAQPFDF 341
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,765,750
Number of Sequences: 369166
Number of extensions: 1005383
Number of successful extensions: 2607
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2470
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2516
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3255600150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)