Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_J13
(801 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase 365 e-100
sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase 358 1e-98
sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Mus... 323 4e-88
sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Mus... 322 6e-88
sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscl... 322 6e-88
sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Mus... 321 1e-87
sp|P53445|ALF1_LAMJA Fructose-bisphosphate aldolase, muscle... 320 4e-87
sp|P53448|ALDOC_CARAU Fructose-bisphosphate aldolase C (Bra... 317 3e-86
sp|P07764|ALF_DROME Fructose-bisphosphate aldolase 316 4e-86
sp|P09117|ALDOC_RAT Fructose-bisphosphate aldolase C (Brain... 314 2e-85
>sp|Q9GP32|ALF_ECHMU Fructose-bisphosphate aldolase
Length = 363
Score = 365 bits (936), Expect = e-100
Identities = 179/229 (78%), Positives = 198/229 (86%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQY DG +FAKWRCVLKI H+PS+ AMLENANVLARYA ICQQN +VPIVEPEVLPD
Sbjct: 135 CAQYYNDGCRFAKWRCVLKISSHNPSYLAMLENANVLARYAFICQQNGLVPIVEPEVLPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H LE AQ+VTE+VLS+VYKALADHHVYLEGTLLKPNMVT GQSCT KY++E NA ATV
Sbjct: 195 GDHDLETAQRVTEQVLSFVYKALADHHVYLEGTLLKPNMVTCGQSCTKKYSVEDNARATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
+ALQRTVP AV GV FLSGGQSE DAT NLNAINKY G+KPW L+FSFGRALQAS + AW
Sbjct: 255 EALQRTVPVAVPGVVFLSGGQSELDATRNLNAINKYPGKKPWALSFSFGRALQASAIAAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 688
+GK ENVKA Q + L LA ANGAA++GKF+G LKTAAG KSLFVANHAY
Sbjct: 315 QGKPENVKAGQAEFLQLAKANGAASLGKFEGELKTAAGQKSLFVANHAY 363
>sp|P53442|ALF_SCHMA Fructose-bisphosphate aldolase
Length = 363
Score = 358 bits (918), Expect = 1e-98
Identities = 177/229 (77%), Positives = 197/229 (86%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CA+Y + G +FAKWRCVLKI H+PS+ AMLENANVLARYASICQQN +VPIVEPEVLPD
Sbjct: 135 CAEYWRLGCRFAKWRCVLKISSHTPSYLAMLENANVLARYASICQQNGLVPIVEPEVLPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L AQ+VTE+VL++VYKALADHHVYLEGTLLKPNMVTAGQ+C YT ++NA ATV
Sbjct: 195 GDHDLLTAQRVTEQVLAFVYKALADHHVYLEGTLLKPNMVTAGQACKKAYTPQENALATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
+ALQRTVPPAV G+TFLSGGQSE DAT NLN INK G KPW LTFSFGRALQASVL W
Sbjct: 255 RALQRTVPPAVPGITFLSGGQSELDATKNLNEINKIPGPKPWALTFSFGRALQASVLATW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 688
KGKKENV AAQ++LL LA ANGAAAVGKF+GN+ T G KSLFVANHAY
Sbjct: 315 KGKKENVHAAQEELLKLAKANGAAAVGKFEGNMGTTLGDKSLFVANHAY 363
>sp|P00883|ALDOA_RABIT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 323 bits (827), Expect = 4e-88
Identities = 161/230 (70%), Positives = 189/230 (82%), Gaps = 1/230 (0%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDGA FAKWRCVLKIG H+PS A++ENANVLARYASICQQN IVPIVEPE+LPD
Sbjct: 135 CAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ Q VTE+VL+ VYKAL+DHH+YLEGTLLKPNMVT G +CT KY+ E+ A ATV
Sbjct: 195 GDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKYSHEEIAMATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
AL+RTVPPAV GVTFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW
Sbjct: 255 TALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 688
GKKEN+KAAQ++ + A AN A GK+ + + AA +SLF++NHAY
Sbjct: 315 GGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFISNHAY 364
>sp|P05064|ALDOA_MOUSE Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Aldolase
1)
Length = 364
Score = 322 bits (826), Expect = 6e-88
Identities = 161/230 (70%), Positives = 190/230 (82%), Gaps = 1/230 (0%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDGA FAKWRCVLKIG H+PS A++ENANVLARYASICQQN IVPIVEPE+LPD
Sbjct: 135 CAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ Q VTE+VL+ VYKAL+DHHVYLEGTLLKPNMVT G +CT K++ E+ A ATV
Sbjct: 195 GDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
AL+RTVPPAV GVTFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW
Sbjct: 255 TALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 688
GKKEN+KAAQ++ + A AN A GK+ + ++ AA +SLF++NHAY
Sbjct: 315 GGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY 364
>sp|P05065|ALDOA_RAT Fructose-bisphosphate aldolase A (Muscle-type aldolase)
Length = 364
Score = 322 bits (826), Expect = 6e-88
Identities = 161/230 (70%), Positives = 190/230 (82%), Gaps = 1/230 (0%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDGA FAKWRCVLKIG H+PS A++ENANVLARYASICQQN IVPIVEPE+LPD
Sbjct: 135 CAQYKKDGADFAKWRCVLKIGEHTPSSLAIMENANVLARYASICQQNGIVPIVEPEILPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ Q VTE+VL+ VYKAL+DHHVYLEGTLLKPNMVT G +CT K++ E+ A ATV
Sbjct: 195 GDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
AL+RTVPPAV GVTFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW
Sbjct: 255 TALRRTVPPAVPGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 688
GKKEN+KAAQ++ + A AN A GK+ + ++ AA +SLF++NHAY
Sbjct: 315 GGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAAASESLFISNHAY 364
>sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A (Muscle-type aldolase) (Lung
cancer antigen NY-LU-1)
Length = 364
Score = 321 bits (823), Expect = 1e-87
Identities = 160/230 (69%), Positives = 189/230 (82%), Gaps = 1/230 (0%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDGA FAKWRCVLKIG H+PS A++ENANVLARYASICQQN IVPIVEPE+LPD
Sbjct: 135 CAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ Q VTE+VL+ VYKAL+DHH+YLEGTLLKPNMVT G +CT K++ E+ A ATV
Sbjct: 195 GDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
AL+RTVPPAV G+TFLSGGQSE +A+INLNAINK KPW LTFS+GRALQAS L+AW
Sbjct: 255 TALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKT-AAGGKSLFVANHAY 688
GKKEN+KAAQ++ + A AN A GK+ + + AA +SLFV+NHAY
Sbjct: 315 GGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY 364
>sp|P53445|ALF1_LAMJA Fructose-bisphosphate aldolase, muscle type
Length = 363
Score = 320 bits (819), Expect = 4e-87
Identities = 157/229 (68%), Positives = 186/229 (81%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDGA FAKWRCVLKI P++PS +++ENANVLARYA+ICQQN +VPIVEPE+LPD
Sbjct: 135 CAQYKKDGADFAKWRCVLKISPNTPSRLSIVENANVLARYATICQQNGLVPIVEPEILPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ Q +TE+VL+ YKAL+DHHVYLEGTLLKPNMVT G + EQ A AT+
Sbjct: 195 GDHDLKTCQYITEKVLAATYKALSDHHVYLEGTLLKPNMVTVGTAAPASTRPEQVAMATL 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
AL+RTVPPAV G+TFLSGGQSE DA+I+LNAINK H KPW LTFS+GRALQASVL+AW
Sbjct: 255 TALRRTVPPAVPGITFLSGGQSEEDASIHLNAINKLHLIKPWALTFSYGRALQASVLKAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 688
GKKEN+KAAQD+L+ A NG A+ G++ AA G+SLFVANHAY
Sbjct: 315 GGKKENLKAAQDELMRRAKINGQASKGEYKPTGTGAAAGESLFVANHAY 363
>sp|P53448|ALDOC_CARAU Fructose-bisphosphate aldolase C (Brain-type aldolase)
Length = 363
Score = 317 bits (811), Expect = 3e-86
Identities = 159/229 (69%), Positives = 183/229 (79%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDGA FAKWR VLKI SPS A++ENANVLARYASICQQN IVPIVEPE+LPD
Sbjct: 135 CAQYKKDGADFAKWRSVLKISETSPSELAIMENANVLARYASICQQNGIVPIVEPEILPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ Q VTE+VL+ YKAL+DHHVYLEGTLLKPNMVTAG SC TK++ ++ A ATV
Sbjct: 195 GDHDLKRCQYVTEKVLAACYKALSDHHVYLEGTLLKPNMVTAGHSCPTKFSNQEIAMATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
AL+RTVPPAV GVTFLSGGQSE +A+INLNAIN KPW LTFS+GRALQAS L AW
Sbjct: 255 TALRRTVPPAVTGVTFLSGGQSEEEASINLNAINNCPLTKPWALTFSYGRALQASALSAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 688
+G KEN KAA ++ L A ANG AA GK+ + + G+SL+VANHAY
Sbjct: 315 RGVKENEKAATEEFLKRAEANGLAAQGKYVSSGMDGSAGQSLYVANHAY 363
>sp|P07764|ALF_DROME Fructose-bisphosphate aldolase
Length = 361
Score = 316 bits (810), Expect = 4e-86
Identities = 164/229 (71%), Positives = 185/229 (80%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDG FAKWRCVLKIG ++PS+Q++LENANVLARYASICQ IVPIVEPEVLPD
Sbjct: 135 CAQYKKDGCDFAKWRCVLKIGKNTPSYQSILENANVLARYASICQSQRIVPIVEPEVLPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ AQKVTE VL+ VYKAL+DHHVYLEGTLLKPNMVTAGQS K T E+ A ATV
Sbjct: 195 GDHDLDRAQKVTETVLAAVYKALSDHHVYLEGTLLKPNMVTAGQS-AKKNTPEEIALATV 253
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
+AL+RTVP AV GVTFLSGGQSE +AT+NL+AIN +PW LTFS+GRALQASVL AW
Sbjct: 254 QALRRTVPAAVTGVTFLSGGQSEEEATVNLSAINNVPLIRPWALTFSYGRALQASVLRAW 313
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 688
GKKEN+ A Q++LL A ANG AA GK+ AG SLFVANHAY
Sbjct: 314 AGKKENIAAGQNELLKRAKANGDAAQGKYVAG-SAGAGSGSLFVANHAY 361
>sp|P09117|ALDOC_RAT Fructose-bisphosphate aldolase C (Brain-type aldolase)
Length = 363
Score = 314 bits (805), Expect = 2e-85
Identities = 154/229 (67%), Positives = 184/229 (80%)
Frame = +2
Query: 2 CAQYKKDGAQFAKWRCVLKIGPHSPSHQAMLENANVLARYASICQQNAIVPIVEPEVLPD 181
CAQYKKDGA FAKWRCVLKI +PS A+LENANVLARYASICQQN IVPIVEPE+LPD
Sbjct: 135 CAQYKKDGADFAKWRCVLKISDRTPSALAILENANVLARYASICQQNGIVPIVEPEILPD 194
Query: 182 GNHSLEEAQKVTEEVLSYVYKALADHHVYLEGTLLKPNMVTAGQSCTTKYTMEQNAEATV 361
G+H L+ Q VTE+VL+ VYKAL+DHHVYLEGTLLKPNMVT G +C KY+ E+ A ATV
Sbjct: 195 GDHDLKRCQFVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATV 254
Query: 362 KALQRTVPPAVAGVTFLSGGQSESDATINLNAINKYHGRKPWPLTFSFGRALQASVLEAW 541
AL+RTVPPAV GVTFLSGGQSE +A++NLNAIN+ +PW LTFS+GRALQAS L AW
Sbjct: 255 TALRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCSLPRPWALTFSYGRALQASALSAW 314
Query: 542 KGKKENVKAAQDQLLHLASANGAAAVGKFDGNLKTAAGGKSLFVANHAY 688
+G+++N AA ++ + A NG AA GK++G+ A +SL+VANHAY
Sbjct: 315 RGQRDNAGAATEEFIKRAEMNGLAAQGKYEGSGDGGAAAQSLYVANHAY 363
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,296,994
Number of Sequences: 369166
Number of extensions: 2044880
Number of successful extensions: 5266
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5060
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5224
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7570361805
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)