Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_J11
(792 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NRR5|UBQL4_HUMAN Ubiquilin-4 (Ataxin-1 ubiquitin-like ... 88 3e-17
sp|Q99NB8|UBQL4_MOUSE Ubiquilin-4 (Ataxin-1 ubiquitin-like ... 86 1e-16
sp|Q8R317|UBQL1_MOUSE Ubiquilin-1 (Protein linking IAP with... 63 8e-10
sp|Q9UHD9|UBQL2_HUMAN Ubiquilin-2 (Protein linking IAP with... 63 8e-10
sp|Q9UMX0|UBQL1_HUMAN Ubiquilin-1 (Protein linking IAP with... 63 1e-09
sp|Q9JJP9|UBQL1_RAT Ubiquilin-1 (Protein linking IAP with c... 63 1e-09
sp|Q9QZM0|UBQL2_MOUSE Ubiquilin-2 (Protein linking IAP with... 60 7e-09
sp|Q9H347|UBQL3_HUMAN Ubiquilin-3 49 1e-05
sp|Q10169|DPH1_SCHPO Deubiquitination-protection protein dph1 45 2e-04
sp|Q8C5U9|UBQL3_MOUSE Ubiquilin-3 44 7e-04
>sp|Q9NRR5|UBQL4_HUMAN Ubiquilin-4 (Ataxin-1 ubiquitin-like interacting protein A1U)
Length = 601
Score = 87.8 bits (216), Expect = 3e-17
Identities = 63/195 (32%), Positives = 83/195 (42%), Gaps = 1/195 (0%)
Frame = +1
Query: 34 PRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAFERPEVRNALTNP 210
P ++S+++TL NP F + N P A NPQLQEQLR +P LQ + PE + LTNP
Sbjct: 404 PYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNP 463
Query: 211 RVLQAIFXXXXXXXXXXXEAPHLXXXXXXXXXXXXXXXXXXXXXXXXXGGXXXXXXXXXX 390
R +QA+ EAP L
Sbjct: 464 RAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT 523
Query: 391 XXXXXXXXXXXXXXXXXXXXNPGAGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRAL 570
G+G NS V PE + +LE + MGF NR+ANL+AL
Sbjct: 524 SSPTGASSAQQQLMQQMIQLLAGSG-NSQV-QTPEVRFQQQLEQLNSMGFINREANLQAL 581
Query: 571 IETFGDVNAAVNRIL 615
I T GD+NAA+ R+L
Sbjct: 582 IATGGDINAAIERLL 596
>sp|Q99NB8|UBQL4_MOUSE Ubiquilin-4 (Ataxin-1 ubiquitin-like interacting protein A1U)
Length = 596
Score = 85.9 bits (211), Expect = 1e-16
Identities = 62/195 (31%), Positives = 83/195 (42%), Gaps = 1/195 (0%)
Frame = +1
Query: 34 PRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAFERPEVRNALTNP 210
P ++++++TL NP F + N P A NPQLQEQLR +P LQ + PE + LTNP
Sbjct: 399 PYMRTMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRLQLPVFLQQMQNPESLSILTNP 458
Query: 211 RVLQAIFXXXXXXXXXXXEAPHLXXXXXXXXXXXXXXXXXXXXXXXXXGGXXXXXXXXXX 390
R +QA+ EAP L
Sbjct: 459 RAMQALLQIQQGLQTLQTEAPGLVPSLGSFGTPRTSVPLAGSNSGSSAEAPTSSPGVPAT 518
Query: 391 XXXXXXXXXXXXXXXXXXXXNPGAGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRAL 570
G+G NS V PE + +LE + MGF NR+ANL+AL
Sbjct: 519 SPPSAGSNAQQQLMQQMIQLLSGSG-NSQV-PMPEVRFQQQLEQLNSMGFINREANLQAL 576
Query: 571 IETFGDVNAAVNRIL 615
I T GD+NAA+ R+L
Sbjct: 577 IATGGDINAAIERLL 591
>sp|Q8R317|UBQL1_MOUSE Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
Length = 582
Score = 63.2 bits (152), Expect = 8e-10
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = +1
Query: 4 LHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAFER 180
+ N+L + P ++S++++L NP + N+P A NPQLQEQ+R +P LQ +
Sbjct: 385 MQNMLSA---PYMRSMLQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQN 441
Query: 181 PEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 279
P+ +A++NPR +QA+ EAP L
Sbjct: 442 PDTLSAMSNPRAMQALLQIQQGLQTLATEAPGL 474
Score = 53.5 bits (127), Expect = 6e-07
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +1
Query: 460 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 627
AG+N + +PE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 527 AGVNPQLQ-SPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 581
Score = 33.9 bits (76), Expect = 0.52
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +1
Query: 16 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 180
L + N +QS ++ L SNP+ + N +NP L QL + PQ+ Q +R
Sbjct: 154 LNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 213
Query: 181 PEVRNALTNPRVLQ 222
PE+ + L NP +++
Sbjct: 214 PEISHMLNNPDIMR 227
>sp|Q9UHD9|UBQL2_HUMAN Ubiquilin-2 (Protein linking IAP with cytoskeleton-2) (PLIC-2)
(hPLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2
homolog) (Chap1)
Length = 624
Score = 63.2 bits (152), Expect = 8e-10
Identities = 33/93 (35%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = +1
Query: 4 LHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAFER 180
+ N+L + P ++S++++L NP + NSP ANPQLQEQ+R +P LQ +
Sbjct: 383 IQNMLSA---PYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQN 439
Query: 181 PEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 279
P+ +A++NPR +QA+ EAP L
Sbjct: 440 PDTLSAMSNPRAMQALMQIQQGLQTLATEAPGL 472
Score = 56.2 bits (134), Expect = 1e-07
Identities = 28/56 (50%), Positives = 37/56 (66%)
Frame = +1
Query: 460 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 627
AG N+ NPE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 568 AGANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQP 623
Score = 32.0 bits (71), Expect = 2.0
Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +1
Query: 16 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 180
L S N +QS ++ L ++P+ + N +NP L QL + PQ+ Q +R
Sbjct: 159 LSSTNFSELQSQMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 218
Query: 181 PEVRNALTNPRVLQ 222
PE+ + L NP +++
Sbjct: 219 PEISHLLNNPDIMR 232
>sp|Q9UMX0|UBQL1_HUMAN Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
(hPLIC-1)
Length = 589
Score = 62.8 bits (151), Expect = 1e-09
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = +1
Query: 4 LHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAFER 180
+ N+L + P ++S++++L NP + N+P A NPQLQEQ+R +P LQ +
Sbjct: 391 MQNMLSA---PYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQN 447
Query: 181 PEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 279
P+ +A++NPR +QA+ EAP L
Sbjct: 448 PDTLSAMSNPRAMQALLQIQQGLQTLATEAPGL 480
Score = 55.5 bits (132), Expect = 2e-07
Identities = 28/56 (50%), Positives = 39/56 (69%)
Frame = +1
Query: 460 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 627
AG+N + NPE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 534 AGVNPQLQ-NPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 588
Score = 33.9 bits (76), Expect = 0.52
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +1
Query: 16 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 180
L + N +QS ++ L SNP+ + N +NP L QL + PQ+ Q +R
Sbjct: 163 LNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 222
Query: 181 PEVRNALTNPRVLQ 222
PE+ + L NP +++
Sbjct: 223 PEISHMLNNPDIMR 236
>sp|Q9JJP9|UBQL1_RAT Ubiquilin-1 (Protein linking IAP with cytoskeleton-1) (PLIC-1)
Length = 582
Score = 62.8 bits (151), Expect = 1e-09
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 1/93 (1%)
Frame = +1
Query: 4 LHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAFER 180
+ N+L + P ++S++++L NP + N+P A NPQLQEQ+R +P LQ +
Sbjct: 385 MQNMLSA---PYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQN 441
Query: 181 PEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 279
P+ +A++NPR +QA+ EAP L
Sbjct: 442 PDTLSAMSNPRAMQALLQIQQGLQTLATEAPGL 474
Score = 53.5 bits (127), Expect = 6e-07
Identities = 27/56 (48%), Positives = 39/56 (69%)
Frame = +1
Query: 460 AGLNSAVGGNPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 627
AG+N + +PE + +LE ++ MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 527 AGVNPQLQ-SPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLLGSQP 581
Score = 34.7 bits (78), Expect = 0.31
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Frame = +1
Query: 16 LGSFNDPRIQSLIET-LRSNPQFTEMAIAN---SPAAANPQLQEQLRNSMPQVLQAFER- 180
L + N +QS ++ L SNP+ + N +NP L QL + PQ+ Q +R
Sbjct: 154 LNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRN 213
Query: 181 PEVRNALTNPRVLQ 222
PE+ + L NP +++
Sbjct: 214 PEISHMLNNPNIMR 227
>sp|Q9QZM0|UBQL2_MOUSE Ubiquilin-2 (Protein linking IAP with cytoskeleton-2) (PLIC-2)
(Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog)
(Chap1)
Length = 638
Score = 60.1 bits (144), Expect = 7e-09
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Frame = +1
Query: 4 LHNLLGSFNDPRIQSLIETLRSNPQFTEMAIANSPA-AANPQLQEQLRNSMPQVLQAFER 180
+ N+L + P ++S++++L NP + +SP +NPQLQEQ+R +P LQ +
Sbjct: 397 IQNMLSA---PYMRSMMQSLSQNPDMAAQMMLSSPLFTSNPQLQEQMRPQLPNFLQQMQN 453
Query: 181 PEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 279
PE A++NPR +QA+ EAP L
Sbjct: 454 PETIAAMSNPRAMQALMQIQQGLQTLATEAPGL 486
Score = 53.5 bits (127), Expect = 6e-07
Identities = 25/47 (53%), Positives = 33/47 (70%)
Frame = +1
Query: 487 NPEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQFDP 627
NPE + +LE + MGF NR+ANL+ALI T GD+NAA+ R+L P
Sbjct: 591 NPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQP 637
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = +1
Query: 22 SFNDPRIQSLIETLRSNPQFTEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVRNAL 201
SF + SL ++P FTE+ Q+Q+QL S ++Q E P V++ L
Sbjct: 156 SFGLGSLSSLSNLGLNSPNFTEL---------RNQMQQQLLASPEMMIQIMENPFVQSML 206
Query: 202 TNPRVLQAI 228
+NP +++ +
Sbjct: 207 SNPDLMRQL 215
Score = 30.0 bits (66), Expect = 7.5
Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Frame = +1
Query: 115 ANPQLQEQLRNSMPQVLQAFER-PEVRNALTNPRVLQ 222
+NP L QL + PQ+ Q +R PE+ + L NP +++
Sbjct: 207 SNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMR 243
>sp|Q9H347|UBQL3_HUMAN Ubiquilin-3
Length = 655
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/56 (48%), Positives = 36/56 (64%), Gaps = 5/56 (8%)
Frame = +1
Query: 466 LNSAVGGNPEQL-----YSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRILQ 618
L V NP+QL + +LE + MGF NR+ANL+ALI T GDV+AAV ++ Q
Sbjct: 599 LQDLVSTNPQQLQPEAHFQVQLEQLRSMGFLNREANLQALIATGGDVDAAVEKLRQ 654
>sp|Q10169|DPH1_SCHPO Deubiquitination-protection protein dph1
Length = 354
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/70 (35%), Positives = 37/70 (52%)
Frame = +1
Query: 13 LLGSFNDPRIQSLIETLRSNPQFTEMAIANSPAAANPQLQEQLRNSMPQVLQAFERPEVR 192
L ++P +QS I + SNPQ +M I +SP LRN+ P V Q + PE R
Sbjct: 144 LANMLSNPMVQSSINEMFSNPQMLDMIINSSP---------HLRNAPPYVRQMMQSPEFR 194
Query: 193 NALTNPRVLQ 222
A+T+P ++
Sbjct: 195 RAMTDPDTMR 204
Score = 34.7 bits (78), Expect = 0.31
Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 12/64 (18%)
Frame = +1
Query: 460 AGLNSAVGGN------------PEQLYSSELETMAQMGFPNRQANLRALIETFGDVNAAV 603
AGL + +GG PE+ Y+ +L + +MGF + + N++AL + G+V A+
Sbjct: 288 AGLGAGLGGAASPPAPAQDTRPPEERYAEQLSQLNEMGFVDFERNVQALRRSGGNVQGAI 347
Query: 604 NRIL 615
+L
Sbjct: 348 ESLL 351
>sp|Q8C5U9|UBQL3_MOUSE Ubiquilin-3
Length = 658
Score = 43.5 bits (101), Expect = 7e-04
Identities = 24/54 (44%), Positives = 34/54 (62%), Gaps = 5/54 (9%)
Frame = +1
Query: 466 LNSAVGGNPEQL-----YSSELETMAQMGFPNRQANLRALIETFGDVNAAVNRI 612
L + NP+QL + +LE + MGF N +ANL+ALI T GDV+AAV ++
Sbjct: 602 LQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATEGDVDAAVEKL 655
Score = 30.0 bits (66), Expect = 7.5
Identities = 15/53 (28%), Positives = 26/53 (49%)
Frame = +1
Query: 121 PQLQEQLRNSMPQVLQAFERPEVRNALTNPRVLQAIFXXXXXXXXXXXEAPHL 279
P++Q ++ +P +L ++ A+ NPRV+QA+ EAP L
Sbjct: 498 PRIQNEIHQQLPLLLH------LQTAMANPRVMQALLQIEQGLQILATEAPRL 544
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,900,318
Number of Sequences: 369166
Number of extensions: 1470200
Number of successful extensions: 3264
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3147
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3257
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)