Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_H23
(482 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1... 127 1e-29
sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1... 125 7e-29
sp|Q9BXI2|ORNT2_HUMAN Mitochondrial ornithine transporter 2... 122 3e-28
sp|Q01356|ARG13_NEUCR Amino acid transporter arg-13 71 1e-12
sp|Q27257|DIF1_CAEEL Protein dif-1 70 3e-12
sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine ... 70 3e-12
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine ... 67 3e-11
sp|Q10248|YD1K_SCHPO Putative mitochondrial carrier C4G9.20c 65 1e-10
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine ... 64 2e-10
sp|Q12375|ORT1_YEAST Mitochondrial ornithine carrier protein 64 2e-10
>sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1 (Solute carrier family 25
member 15)
Length = 301
Score = 127 bits (319), Expect = 1e-29
Identities = 68/158 (43%), Positives = 94/158 (59%), Gaps = 1/158 (0%)
Frame = +3
Query: 6 IGFLCGVNGGIATVYVGQPLDTVKVKMQMFPALYKNAFTCFMNTLKKDGIYRGLYAGTVP 185
I G GG A V GQP DT+KVKMQ FP LY+ C + T + G +RG Y GT P
Sbjct: 11 IDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVG-FRGFYKGTSP 69
Query: 186 ALVANVAENSVLFCALPPCKSLVSVILNKPVK-ELNPLESGCAGGIAAIFSSLTLCPTEL 362
AL+AN+AENSVLF C+ +V ++ + +L+ L++ AG A+ F++L LCPTEL
Sbjct: 70 ALIANIAENSVLFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTEL 129
Query: 363 VKCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQG 476
VKC+ Q M EM +GK + + W + K++F G
Sbjct: 130 VKCRLQTMYEMETSGK--IAASQNTVWSVVKEIFRKDG 165
>sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1 (Solute carrier family 25,
member 15)
Length = 301
Score = 125 bits (313), Expect = 7e-29
Identities = 70/159 (44%), Positives = 93/159 (58%), Gaps = 2/159 (1%)
Frame = +3
Query: 6 IGFLCGVNGGIATVYVGQPLDTVKVKMQMFPALYKNAFTCFMNTLKKDGIYRGLYAGTVP 185
I G GG A V GQP DT+KVKMQ FP LY+ C + T + G +RG Y GT P
Sbjct: 11 IDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVG-FRGFYKGTSP 69
Query: 186 ALVANVAENSVLFCALPPCKSLVSVI--LNKPVKELNPLESGCAGGIAAIFSSLTLCPTE 359
AL+AN+AENSVLF C+ +V + L+K K L+ L++ AG A+ F++L LCPTE
Sbjct: 70 ALIANIAENSVLFMCYGFCQQVVRKVAGLDKQAK-LSDLQNAAAGSFASAFAALVLCPTE 128
Query: 360 LVKCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQG 476
LVKC+ Q M EM +GK + + W + K + G
Sbjct: 129 LVKCRLQTMYEMETSGKIAK--SQNTVWSVIKSILRKDG 165
>sp|Q9BXI2|ORNT2_HUMAN Mitochondrial ornithine transporter 2 (Solute carrier family 25
member 2)
Length = 301
Score = 122 bits (307), Expect = 3e-28
Identities = 71/159 (44%), Positives = 92/159 (57%), Gaps = 2/159 (1%)
Frame = +3
Query: 6 IGFLCGVNGGIATVYVGQPLDTVKVKMQMFPALYKNAFTCFMNTLKKDGIYRGLYAGTVP 185
I G GG A V GQP DT+KVKMQ FP LYK CF+ T + G+ RG Y GT P
Sbjct: 11 IDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGL-RGFYKGTGP 69
Query: 186 ALVANVAENSVLFCALPPCKSLVSVI--LNKPVKELNPLESGCAGGIAAIFSSLTLCPTE 359
AL+A VAENSVLF C+ V + ++K K L+ L++ AG A+ F++L LCPTE
Sbjct: 70 ALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAK-LSDLQTAAAGSFASAFAALALCPTE 128
Query: 360 LVKCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQG 476
LVKC+ Q M EM +GK + + W + K + G
Sbjct: 129 LVKCRLQTMYEMEMSGKIAK--SHNTIWSVVKGILKKDG 165
>sp|Q01356|ARG13_NEUCR Amino acid transporter arg-13
Length = 363
Score = 71.2 bits (173), Expect = 1e-12
Identities = 55/159 (34%), Positives = 73/159 (45%), Gaps = 5/159 (3%)
Frame = +3
Query: 21 GVNGGIATVYVGQPLDTVKVKMQM----FPALYKNAFTCFMNTLKKDGIYRGLYAGTVPA 188
G GI Y+ P DTVKV++Q P Y CF +++ DG + GLY G
Sbjct: 49 GSAAGIVGKYIEYPFDTVKVRLQSQPDHLPLRYTGPLDCFRQSIRADG-FLGLYRGISAP 107
Query: 189 LVANVAENSVLFCALPPCKSLVSVILNKPV-KELNPLESGCAGGIAAIFSSLTLCPTELV 365
LV ENS LF +SL+ P EL+ GG + F+SL L P ELV
Sbjct: 108 LVGAALENSSLFFFERIGRSLLYSSGFAPRDSELSLSALWFTGGFSGAFTSLILTPVELV 167
Query: 366 KCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQGFR 482
KCK Q E AG ++ P + K++F +G R
Sbjct: 168 KCKIQVPDEPGGAGARQRQLK---PIPVIKEIFRHEGLR 203
>sp|Q27257|DIF1_CAEEL Protein dif-1
Length = 312
Score = 70.1 bits (170), Expect = 3e-12
Identities = 47/165 (28%), Positives = 76/165 (46%), Gaps = 7/165 (4%)
Frame = +3
Query: 3 IIGFLCGVNGGIATVYVGQPLDTVKVKMQMFP-------ALYKNAFTCFMNTLKKDGIYR 161
++ F+ G GG TV VG P DTVKV++Q P + A C T+ K+G +
Sbjct: 5 LLNFIAGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFF- 63
Query: 162 GLYAGTVPALVANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESGCAGGIAAIFSSL 341
LY G LV +V F K L P +E+ +++ AG +A +F+++
Sbjct: 64 ALYKGMAAPLVGVSPLFAVFFGGCAVGKWLQQ---TDPSQEMTFIQNANAGALAGVFTTI 120
Query: 342 TLCPTELVKCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQG 476
+ P E +KC Q +AG + + GP + K+++ G
Sbjct: 121 VMVPGERIKCLLQVQ----QAGSAGSGVHYDGPLDVVKKLYKQGG 161
>sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine carrier-like protein (A BOUT
DE SOUFFLE) (Carnitine/acylcarnitine translocase-like
protein) (CAC-like protein)
Length = 300
Score = 70.1 bits (170), Expect = 3e-12
Identities = 50/162 (30%), Positives = 70/162 (43%), Gaps = 10/162 (6%)
Frame = +3
Query: 21 GVNGGIATVYVGQPLDTVKVKMQMFPA-------LYKNAFTCFMNTLKKDGIYRGLYAGT 179
G GG A + VG P DT+KVK+Q P Y A T+ +G +GLY G
Sbjct: 11 GTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGT-KGLYKGM 69
Query: 180 VPALVANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESGCAGGIAAIFSSLTLCPTE 359
L A N+VLF + L+ P+ +G G A F + CPTE
Sbjct: 70 GAPLATVAAFNAVLFTVRGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSFLA---CPTE 126
Query: 360 LVKCKQQAMREMIEAGKSSMKITDT---GPWKICKQVFSSQG 476
L+KC+ QA + A +S + GP + + V S+G
Sbjct: 127 LIKCRLQAQGALAGASTTSSVVAAVKYGGPMDVARHVLRSEG 168
Score = 32.3 bits (72), Expect = 0.59
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Frame = +3
Query: 60 PLDTVKVKMQMFPALYKN-----AFTCFMNTLKKDGIYRGLYAGTVPALVANVAENSVLF 224
P D VK +Q+ YKN + F LK +G+ +GLY G PA+ +V N+ F
Sbjct: 233 PTDVVKSVLQVDD--YKNPRYTGSMDAFRKILKSEGV-KGLYKGFGPAMARSVPANAACF 289
Query: 225 CALPPCKS 248
A +S
Sbjct: 290 LAYEMTRS 297
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 66.6 bits (161), Expect = 3e-11
Identities = 50/163 (30%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Frame = +3
Query: 15 LCGVNGGIATVYVGQPLDTVKVKMQM-------FPALYKNAFTCFMNTLKKDGIYRGLYA 173
L G GG+ V+VG PLDTVKV++Q P +Y F CF TL ++GI RGLY
Sbjct: 15 LAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGI-RGLYR 73
Query: 174 GTVPALVANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESGCAGGIAAIFSSLTLCP 353
G ++ +V F K L P L+ + AG ++ IF++ + P
Sbjct: 74 GMAAPIIGVTPMFAVCFFGFGLGKKLQQ---KHPEDVLSYPQLFAAGMLSGIFTTGIMTP 130
Query: 354 TELVKCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQGFR 482
E +KC +++ SS + TG K+++ G R
Sbjct: 131 GERIKC-------LLQIQASSGETKYTGTLDCAKKLYQEFGIR 166
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Frame = +3
Query: 12 FLCGVNGGIATVYVGQPLDTVKVKMQMFPALYKNAFTCFMNTLKKDGIY-----RGLYAG 176
F G+ GI T + P + +K +Q+ + + +T ++ KK +Y RG+Y G
Sbjct: 114 FAAGMLSGIFTTGIMTPGERIKCLLQIQASSGETKYTGTLDCAKK--LYQEFGIRGIYKG 171
Query: 177 TVPALVANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESGCAGGIAAIFSSLTLCPT 356
TV L+ +V + + F K++ + K V EL+ AGGIA IF+ P
Sbjct: 172 TVVTLMRDVPASGMYFMTYEWVKNIFTP-EGKRVSELSVPRVLVAGGIAGIFNWAVAIPP 230
Query: 357 ELVKCKQQ 380
+++K + Q
Sbjct: 231 DVLKSRFQ 238
>sp|Q10248|YD1K_SCHPO Putative mitochondrial carrier C4G9.20c
Length = 302
Score = 64.7 bits (156), Expect = 1e-10
Identities = 53/158 (33%), Positives = 72/158 (45%), Gaps = 3/158 (1%)
Frame = +3
Query: 12 FLCGVNGGIATVYVGQPLDTVKVKMQM---FPALYKNAFTCFMNTLKKDGIYRGLYAGTV 182
FL GV+GG+A V VGQP D VKV++Q +Y NA C K +G+ Y GTV
Sbjct: 21 FLAGVSGGVAQVLVGQPFDCVKVRLQSQSNVSPIYNNALDCVKKISKNEGL-AAFYKGTV 79
Query: 183 PALVANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESGCAGGIAAIFSSLTLCPTEL 362
L+ S+ F CK S PV SG G+A +S + P E
Sbjct: 80 LPLLGIGFCVSIQFTTFEYCKRFFSRD-GTPVTMPQYYVSGAISGLA---NSFLVGPVEH 135
Query: 363 VKCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQG 476
V+ + Q I+ GK+ + GPW K++ S G
Sbjct: 136 VRIRLQ-----IQTGKN---VLYHGPWDCIKKISSQYG 165
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 63.9 bits (154), Expect = 2e-10
Identities = 50/163 (30%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +3
Query: 15 LCGVNGGIATVYVGQPLDTVKVKMQM-------FPALYKNAFTCFMNTLKKDGIYRGLYA 173
L G GG+ V+VG PLDTVKV++Q P +Y F CF TL ++GI GLY
Sbjct: 15 LAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGI-TGLYR 73
Query: 174 GTVPALVANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESGCAGGIAAIFSSLTLCP 353
G ++ +V F K L P L+ + AG ++ +F++ + P
Sbjct: 74 GMAAPIIGVTPMFAVCFFGFGLGKKLQQ---KHPEDVLSYPQLFAAGMLSGVFTTGIMTP 130
Query: 354 TELVKCKQQAMREMIEAGKSSMKITDTGPWKICKQVFSSQGFR 482
E +KC Q I+A K TG K+++ G R
Sbjct: 131 GERIKCLLQ-----IQASSGESKY--TGTLDCAKKLYQEFGIR 166
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 5/128 (3%)
Frame = +3
Query: 12 FLCGVNGGIATVYVGQPLDTVKVKMQMFPALYKNAFTCFMNTLKKDGIY-----RGLYAG 176
F G+ G+ T + P + +K +Q+ + ++ +T ++ KK +Y RG+Y G
Sbjct: 114 FAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKK--LYQEFGIRGIYKG 171
Query: 177 TVPALVANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESGCAGGIAAIFSSLTLCPT 356
TV L+ +V + + F K++ + K V EL+ AGGIA IF+ P
Sbjct: 172 TVLTLMRDVPASGMYFMTYEWLKNIFTP-EGKRVSELSAPRILVAGGIAGIFNWAVAIPP 230
Query: 357 ELVKCKQQ 380
+++K + Q
Sbjct: 231 DVLKSRFQ 238
Score = 29.3 bits (64), Expect = 5.0
Identities = 23/69 (33%), Positives = 32/69 (46%), Gaps = 8/69 (11%)
Frame = +3
Query: 24 VNGGIATVY---VGQPLDTVKVKMQMFP-ALYKNAFTCFMNTLKKD----GIYRGLYAGT 179
V GGIA ++ V P D +K + Q P Y N F + L +D +Y+G A
Sbjct: 214 VAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVM 273
Query: 180 VPALVANVA 206
+ A AN A
Sbjct: 274 IRAFPANAA 282
>sp|Q12375|ORT1_YEAST Mitochondrial ornithine carrier protein
Length = 292
Score = 63.9 bits (154), Expect = 2e-10
Identities = 43/137 (31%), Positives = 64/137 (46%), Gaps = 7/137 (5%)
Frame = +3
Query: 24 VNGGIATV---YVGQPLDTVKVKMQMFPA-LYKNAFTCFMNTLKKDGIYRGLYAGTVPAL 191
+NG IA + P DTVKV++Q + ++ ++C T + +GI RG + G L
Sbjct: 18 INGSIAGACGKVIEFPFDTVKVRLQTQASNVFPTTWSCIKFTYQNEGIARGFFQGIASPL 77
Query: 192 VANVAENSVLFCALPPCKSLVSVILNKPVKELNPLESG---CAGGIAAIFSSLTLCPTEL 362
V EN+ LF + C + K N G +GG+A +SL L P EL
Sbjct: 78 VGACLENATLFVSYNQCSKFLE-------KHTNVFPLGQILISGGVAGSCASLVLTPVEL 130
Query: 363 VKCKQQAMREMIEAGKS 413
VKCK Q + + K+
Sbjct: 131 VKCKLQVANLQVASAKT 147
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,117,365
Number of Sequences: 369166
Number of extensions: 1129775
Number of successful extensions: 3271
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3094
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3229
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2871696580
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)