Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_G03
(818 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H7E2|TDRD3_HUMAN Tudor domain-containing protein 3 86 2e-16
sp|Q91W18|TDRD3_MOUSE Tudor domain-containing protein 3 80 5e-15
sp|P22682|CBL_MOUSE CBL E3 ubiquitin protein ligase (Signal... 34 0.55
sp|Q90374|PRLR_COLLI Prolactin receptor precursor (PRL-R) 33 0.72
sp|O00443|P3C2A_HUMAN Phosphatidylinositol-4-phosphate 3-ki... 32 2.1
sp|Q5RAY1|P3C2A_PONPY Phosphatidylinositol-4-phosphate 3-ki... 32 2.1
sp|Q10256|MUD1_SCHPO UBA-domain protein mud1 (UBA-domain co... 32 2.7
sp|Q61194|P3C2A_MOUSE Phosphatidylinositol-4-phosphate 3-ki... 32 2.7
sp|Q10255|YD27_SCHPO Hypothetical protein C56F8.07 in chrom... 32 2.7
sp|P04821|CDC25_YEAST Cell division control protein 25 31 3.6
>sp|Q9H7E2|TDRD3_HUMAN Tudor domain-containing protein 3
Length = 651
Score = 85.5 bits (210), Expect = 2e-16
Identities = 70/234 (29%), Positives = 115/234 (49%), Gaps = 19/234 (8%)
Frame = +1
Query: 22 LLKYTITDGVSTIHLLDLQSNPKLNRNNEPGCKVIIKGQTMYKSGMIILIDKINVTCLGG 201
+L+ +TDG + ++ K++ N PG KV + G K+G ++L D N T LGG
Sbjct: 1 MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDS-NTTVLGG 59
Query: 202 KVIDLIRAENIDKT-SKMNRIGLHGTSQGPPKFTPFGNK----LNINMQDIRKFKAMQTE 366
+V LI + ++ SK NR + GT GPP F PFG K + ++ +++ + K +Q
Sbjct: 60 EVEHLIEKWELQRSLSKHNRSNI-GTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQV- 117
Query: 367 TTKENVISDNSEFGDKREAALAEVRKTKDGDT--SAVTDKHSLLDKFHGGGTSKFI--KE 534
T +DN EF +R AA+AEV K+K+ T S L+ G ++ + KE
Sbjct: 118 TMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKE 177
Query: 535 STEKQDQKDSNV----------AYLMSSGFNFTEVQKALKASNNDVNVALDQLL 666
+ K + K V ++ GF+ ++AL + N++ AL+ LL
Sbjct: 178 KSTKSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLL 231
>sp|Q91W18|TDRD3_MOUSE Tudor domain-containing protein 3
Length = 650
Score = 80.5 bits (197), Expect = 5e-15
Identities = 69/234 (29%), Positives = 113/234 (48%), Gaps = 19/234 (8%)
Frame = +1
Query: 22 LLKYTITDGVSTIHLLDLQSNPKLNRNNEPGCKVIIKGQTMYKSGMIILIDKINVTCLGG 201
+L+ +TDG ++ ++ K++ N PG KV + G K+G ++L D N T LGG
Sbjct: 1 MLRVQMTDGHTSCTAVEFSYISKISLNTPPGTKVKLSGTVDIKNGFLLLSDS-NTTVLGG 59
Query: 202 KVIDLIRAENIDKT-SKMNRIGLHGTSQGPPKFTPFGNKLNINMQ----DIRKFKAMQTE 366
+V LI + ++ K NR + G GPP F PFG K N+Q ++ + K +Q
Sbjct: 60 EVEHLIDKWALQRSLLKHNRSNI-GAEGGPPPFLPFGQKCASNVQVDSRELDRRKTLQVS 118
Query: 367 TTKENVISDNSEFGDKREAALAEVRKTKDGDT--SAVTDKHSLLDKFHGGGTSKFI--KE 534
+ +DN EF +R AA+AEV K+K+ T S L+ G ++ + KE
Sbjct: 119 LPAKPA-NDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNIGAAGHRNREVLQKE 177
Query: 535 STEKQDQKDSNV----------AYLMSSGFNFTEVQKALKASNNDVNVALDQLL 666
K + K+ V ++ GF+ ++AL + N++ AL+ LL
Sbjct: 178 KASKSESKNEGVYRELVDEKALKHITEMGFSKEASRQALMDNANNLEAALNVLL 231
>sp|P22682|CBL_MOUSE CBL E3 ubiquitin protein ligase (Signal transduction protein CBL)
(Proto-oncogene c-CBL) (Casitas B-lineage lymphoma
proto-oncogene)
Length = 913
Score = 33.9 bits (76), Expect = 0.55
Identities = 16/49 (32%), Positives = 30/49 (61%)
Frame = +1
Query: 505 GGGTSKFIKESTEKQDQKDSNVAYLMSSGFNFTEVQKALKASNNDVNVA 651
GG T+ + +T Q S + LMS G+++ ++QKAL ++N++ +A
Sbjct: 849 GGATANPV--ATAPSPQLSSEIERLMSQGYSYQDIQKALVIAHNNIEMA 895
>sp|Q90374|PRLR_COLLI Prolactin receptor precursor (PRL-R)
Length = 830
Score = 33.5 bits (75), Expect = 0.72
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Frame = +1
Query: 280 QGPPKFTPFGNKLNINMQDIRKFKAMQTET------TKENVISDNSEFGDKREAALAEVR 441
Q P++ P ++ NM+ R+ + + ++T K+N +D S F + EV
Sbjct: 663 QHQPQY-PITETVHDNMEKHREVENLYSKTDQTTVQVKQNRPNDKSPFSKPKLMDYVEVH 721
Query: 442 KTKDGDTSAVTDKH----SLLDKFHGGGTSKFIKESTEKQDQKDSNVAYLM 582
K + + +AV KH ++K+ GTS KE T+ D N+ LM
Sbjct: 722 KVRQDEVAAVLLKHKENSGKIEKYTVPGTS---KEYTKVSTVVDHNILVLM 769
>sp|O00443|P3C2A_HUMAN Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha
polypeptide (Phosphoinositide 3-Kinase-C2-alpha)
(PtdIns-3-kinase C2 alpha) (PI3K-C2alpha)
Length = 1686
Score = 32.0 bits (71), Expect = 2.1
Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Frame = -2
Query: 703 FRIYLN---VNLLFSEAIGPMQHSHRYYWLLR 617
+ IYLN V L S A+G +Q +H YWLL+
Sbjct: 984 YEIYLNSSLVQFLLSRALGNIQIAHNLYWLLK 1015
>sp|Q5RAY1|P3C2A_PONPY Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha
polypeptide (Phosphoinositide 3-Kinase-C2-alpha)
(PtdIns-3-kinase C2 alpha) (PI3K-C2alpha)
Length = 1685
Score = 32.0 bits (71), Expect = 2.1
Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Frame = -2
Query: 703 FRIYLN---VNLLFSEAIGPMQHSHRYYWLLR 617
+ IYLN V L S A+G +Q +H YWLL+
Sbjct: 982 YEIYLNSSLVQFLLSRALGNIQIAHNLYWLLK 1013
>sp|Q10256|MUD1_SCHPO UBA-domain protein mud1 (UBA-domain containing protein 1)
(DNA-damage inducible protein DDI1 homolog)
Length = 332
Score = 31.6 bits (70), Expect = 2.7
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +1
Query: 559 DSNVAYLMSSGFNFTEVQKALKASNNDVNVALDQLL 666
+S +A L+S GF+ E +AL A+N D++VA LL
Sbjct: 297 NSKIAQLVSMGFDPLEAAQALDAANGDLDVAASFLL 332
>sp|Q61194|P3C2A_MOUSE Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha
polypeptide (Phosphoinositide 3-Kinase-C2-alpha)
(PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170)
Length = 1686
Score = 31.6 bits (70), Expect = 2.7
Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Frame = -2
Query: 703 FRIYLN---VNLLFSEAIGPMQHSHRYYWLLR 617
+ IYLN V L S A+G +Q +H YWLL+
Sbjct: 984 YEIYLNSSLVRFLLSRALGNIQIAHSLYWLLK 1015
>sp|Q10255|YD27_SCHPO Hypothetical protein C56F8.07 in chromosome I
Length = 507
Score = 31.6 bits (70), Expect = 2.7
Identities = 16/36 (44%), Positives = 24/36 (66%)
Frame = +1
Query: 559 DSNVAYLMSSGFNFTEVQKALKASNNDVNVALDQLL 666
+S +A L+S GF+ E +AL A+N D++VA LL
Sbjct: 472 NSKIAQLVSMGFDPLEAAQALDAANGDLDVAASFLL 507
>sp|P04821|CDC25_YEAST Cell division control protein 25
Length = 1589
Score = 31.2 bits (69), Expect = 3.6
Identities = 19/65 (29%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Frame = +1
Query: 289 PKFTPFGNKLNINMQDIRKFKAMQTETTKENVISDNSEFGDKREAALAEVRKTK--DGDT 462
PKF P + +N+ +D+RK ++ +T+ S SE R + L E + +K DG+
Sbjct: 339 PKFPPNDHLVNLYTRDLRKNANIEDSSTR----SKQSESEQNRSSLLMEKQDSKETDGNN 394
Query: 463 SAVTD 477
+++ D
Sbjct: 395 NSIND 399
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.134 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,651,260
Number of Sequences: 369166
Number of extensions: 1588532
Number of successful extensions: 4031
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3893
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4027
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)