Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_F12
(864 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6PER3|MARE3_MOUSE Microtubule-associated protein RP/EB ... 189 7e-48
sp|Q9UPY8|MARE3_HUMAN Microtubule-associated protein RP/EB ... 188 1e-47
sp|Q61166|MARE1_MOUSE Microtubule-associated protein RP/EB ... 188 1e-47
sp|Q66HR2|MARE1_RAT Microtubule-associated protein RP/EB fa... 186 7e-47
sp|Q3ZBD9|MARE1_BOVIN Microtubule-associated protein RP/EB ... 184 2e-46
sp|Q5ZLC7|MARE1_CHICK Microtubule-associated protein RP/EB ... 182 8e-46
sp|Q6V291|MARE1_COTCO Microtubule-associated protein RP/EB ... 181 2e-45
sp|Q6P848|MARE1_XENTR Microtubule-associated protein RP/EB ... 181 2e-45
sp|Q66T82|MARE1_COTJA Microtubule-associated protein RP/EB ... 181 3e-45
sp|Q5R7Z5|MARE1_PONPY Microtubule-associated protein RP/EB ... 181 3e-45
>sp|Q6PER3|MARE3_MOUSE Microtubule-associated protein RP/EB family member 3 (End-binding
protein 3) (EB3) (EB1 protein family member 3) (EBF3)
(RP3)
sp|Q5XIT1|MARE3_RAT Microtubule-associated protein RP/EB family member 3 (End-binding
protein 3) (EB3) (EB1 protein family member 3) (EBF3)
(RP3)
Length = 281
Score = 189 bits (481), Expect = 7e-48
Identities = 112/229 (48%), Positives = 140/229 (61%), Gaps = 5/229 (2%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI+NFKVLQ+ FKK GVDK PV KLVKGKFQDNFEF+QWFK+FFDANYDG +Y+P
Sbjct: 67 LEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKPAMIR- 439
L AR G+ V + S + + P+R S T T+ + S P ++R
Sbjct: 127 LLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRK 186
Query: 440 --PSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRER 613
PSA+ NGG +A+ I L Q D K T+D L +ER
Sbjct: 187 NPPSAR------------------NGGHEADA-----QILELNQQLLDLKLTVDGLEKER 223
Query: 614 DFYFNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAP-DDEPEE 754
DFYF+KLRDIE++CQE + E +PVI+ ++ ILYATEEGFA P DDE EE
Sbjct: 224 DFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPEDDEIEE 272
>sp|Q9UPY8|MARE3_HUMAN Microtubule-associated protein RP/EB family member 3 (End-binding
protein 3) (EB3) (EB1 protein family member 3) (EBF3)
(RP3)
Length = 281
Score = 188 bits (478), Expect = 1e-47
Identities = 111/229 (48%), Positives = 139/229 (60%), Gaps = 5/229 (2%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI+NFKVLQ+ FKK GVDK PV KLVKGKFQDNFEF+QWFK+FFDANYDG +Y+P
Sbjct: 67 LEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKPAMIR- 439
L AR G+ V + S + + P+R S T T+ + S P ++R
Sbjct: 127 LLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRK 186
Query: 440 --PSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRER 613
PSA+ NGG + + I L Q D K T+D L +ER
Sbjct: 187 NPPSAR------------------NGGHETDA-----QILELNQQLVDLKLTVDGLEKER 223
Query: 614 DFYFNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAP-DDEPEE 754
DFYF+KLRDIE++CQE + E +PVI+ ++ ILYATEEGFA P DDE EE
Sbjct: 224 DFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPEDDEIEE 272
>sp|Q61166|MARE1_MOUSE Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 188 bits (478), Expect = 1e-47
Identities = 113/233 (48%), Positives = 148/233 (63%), Gaps = 8/233 (3%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG EYDP
Sbjct: 67 LEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRR--ASATNAITKPTAVKQSTAPKPAMI 436
+AAR G+ AV P SL P S P++ S+T A +P A +++TA
Sbjct: 127 VAARQGQ------ETAVAP---SLVAPALSKPKKPLGSSTAAPQRPIATQRTTA------ 171
Query: 437 RPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERD 616
P A P K G NG D+A +L + ++ L K T+++L +ERD
Sbjct: 172 APKAGPGMVRKNPGVG-------NGDDEA--AELMQQVKVL-------KLTVEDLEKERD 215
Query: 617 FYFNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPD-----DEPEEF 757
FYF KLR+IE++CQE +GE +PV+ ++++ILYAT+EGF PD +E EE+
Sbjct: 216 FYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGFVIPDEGGPQEEQEEY 268
>sp|Q66HR2|MARE1_RAT Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 186 bits (472), Expect = 7e-47
Identities = 112/233 (48%), Positives = 147/233 (63%), Gaps = 8/233 (3%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG EYDP
Sbjct: 67 LEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRR--ASATNAITKPTAVKQSTAPKPAMI 436
+AAR G+ AV P SL P S P++ S + A +P A +++TA
Sbjct: 127 VAARQGQ------ETAVAP---SLVAPALSKPKKPLGSGSAAPQRPIATQRTTA------ 171
Query: 437 RPSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERD 616
P A P K G NG D+A +L + ++ L K T+++L +ERD
Sbjct: 172 APKAGPGMVRKNPGMG-------NGDDEA--AELMQQVKVL-------KLTVEDLEKERD 215
Query: 617 FYFNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPD-----DEPEEF 757
FYF KLR+IE++CQE +GE +PV+ ++++ILYAT+EGF PD +E EE+
Sbjct: 216 FYFGKLRNIELICQENEGENDPVLQRIVDILYATDEGFVIPDEGGPQEEQEEY 268
>sp|Q3ZBD9|MARE1_BOVIN Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 184 bits (468), Expect = 2e-46
Identities = 104/231 (45%), Positives = 139/231 (60%), Gaps = 6/231 (2%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG EYDP
Sbjct: 67 LEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKPAMIRP 442
+AAR G+ ++ P+ AP A+ KP S++ P
Sbjct: 127 VAARQGQ--------------ETAMAPSLVAP-------ALNKPKKPLSSSSAAPQRPIT 165
Query: 443 SAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERDFY 622
+ + T K P + + GD E +L + + L K T+++L +ERDFY
Sbjct: 166 THRTTATPKAGPGVVRKNPGVGNGDD-EAAELMQQVNVL-------KLTVEDLEKERDFY 217
Query: 623 FNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPD-----DEPEEF 757
F KLR+IE++CQE +GE NPV+ ++++ILYAT+EGF PD +E EE+
Sbjct: 218 FGKLRNIELICQENEGENNPVLQRIVDILYATDEGFVIPDEGGPQEEQEEY 268
>sp|Q5ZLC7|MARE1_CHICK Microtubule-associated protein RP/EB family member 1
Length = 258
Score = 182 bits (463), Expect = 8e-46
Identities = 107/226 (47%), Positives = 137/226 (60%), Gaps = 2/226 (0%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFKVLQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG EYDP
Sbjct: 67 LEHEYIQNFKVLQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKPAMIRP 442
+AAR G PN AP + KP K+ AP+ ++
Sbjct: 127 VAAR---------------QGQETVAPNLVAP-------VVNKP---KKPLAPQRPIV-- 159
Query: 443 SAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERDFY 622
Q++ +P GS V GD G IE + + K T+++L +ERDFY
Sbjct: 160 ----AQRTPATPKGSTGMVKKAAGDDESAG----LIEQINVL----KLTVEDLEKERDFY 207
Query: 623 FNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPDD-EPEE 754
F KLR+IE++CQE +GE +PV+ +++EILYAT+EGF PD+ P+E
Sbjct: 208 FGKLRNIELICQENEGENDPVLQRIVEILYATDEGFVIPDEGAPQE 253
>sp|Q6V291|MARE1_COTCO Microtubule-associated protein RP/EB family member 1
Length = 263
Score = 181 bits (460), Expect = 2e-45
Identities = 105/226 (46%), Positives = 133/226 (58%), Gaps = 2/226 (0%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFKVLQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG EYDP
Sbjct: 67 LEHEYIQNFKVLQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKPAMIRP 442
+AAR G PN AP N KP + +P +
Sbjct: 127 VAAR---------------QGQETVAPNLVAP----VMNKPKKPLGTGSAAPQRPIV--- 164
Query: 443 SAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERDFY 622
Q++ +P G V GD G IE + + K T+++L +ERDFY
Sbjct: 165 ----AQRTPATPKGGTGMVKKAAGDDESAG----LIEQINVL----KLTVEDLEKERDFY 212
Query: 623 FNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPDD-EPEE 754
F KLR+IE++CQE +GE +PV+ +++EILYAT+EGF PD+ P+E
Sbjct: 213 FGKLRNIELICQENEGENDPVLQRIVEILYATDEGFVIPDEGAPQE 258
>sp|Q6P848|MARE1_XENTR Microtubule-associated protein RP/EB family member 1
Length = 269
Score = 181 bits (459), Expect = 2e-45
Identities = 104/221 (47%), Positives = 131/221 (59%), Gaps = 1/221 (0%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFKVLQ+ FKK GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG +YDP
Sbjct: 67 LEHEYIQNFKVLQAGFKKMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKDYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKPAMIRP 442
+AAR G+ +S P +AP + Q T P
Sbjct: 127 VAARQGQ--------------ESAPVPVLAAPVLNKPKKPLGSGNTAPQRTVPVQRTAVS 172
Query: 443 SAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERDFY 622
+ P Q PA T+ GD E +L + I L K T+++L +ERDFY
Sbjct: 173 NKPPAQGISKKPA------TVGNGDD-ESAELIQQINVL-------KITVEDLEKERDFY 218
Query: 623 FNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPDD 742
F KLR+IE++CQE +GE +PV+ +++EILYAT+EGF PD+
Sbjct: 219 FGKLRNIELICQENEGESDPVLQRIIEILYATDEGFVIPDE 259
>sp|Q66T82|MARE1_COTJA Microtubule-associated protein RP/EB family member 1
Length = 263
Score = 181 bits (458), Expect = 3e-45
Identities = 105/226 (46%), Positives = 133/226 (58%), Gaps = 2/226 (0%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFKVLQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG EYDP
Sbjct: 67 LEHEYIQNFKVLQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRRASATNAITKPTAVKQSTAPKPAMIRP 442
+AAR G PN AP N KP + +P +
Sbjct: 127 VAAR---------------QGQETVAPNLVAP----VMNKPKKPLGTGSAGPQRPIV--- 164
Query: 443 SAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERDFY 622
Q++ +P G V GD G IE + + K T+++L +ERDFY
Sbjct: 165 ----AQRTPATPKGGTGMVKKAAGDDESAG----LIEQINVL----KLTVEDLEKERDFY 212
Query: 623 FNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPDD-EPEE 754
F KLR+IE++CQE +GE +PV+ +++EILYAT+EGF PD+ P+E
Sbjct: 213 FGKLRNIELICQENEGENDPVLQRIVEILYATDEGFVIPDEGAPQE 258
>sp|Q5R7Z5|MARE1_PONPY Microtubule-associated protein RP/EB family member 1 (APC-binding
protein EB1) (End-binding protein 1) (EB1)
Length = 268
Score = 181 bits (458), Expect = 3e-45
Identities = 106/232 (45%), Positives = 142/232 (61%), Gaps = 7/232 (3%)
Frame = +2
Query: 83 LEHEYINNFKVLQSLFKKHGVDKEAPVSKLVKGKFQDNFEFVQWFKRFFDANYDGHEYDP 262
LEHEYI NFK+LQ+ FK+ GVDK PV KLVKGKFQDNFEFVQWFK+FFDANYDG +YDP
Sbjct: 67 LEHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKDYDP 126
Query: 263 LAARGGEIVQGTGRNAVKPSGDSLQRPNYSAPRR-ASATNAITKPTAVKQSTAPKPAMIR 439
+AAR G+ AV P SL P + P++ S+++A + Q TA P
Sbjct: 127 VAARQGQ------ETAVAP---SLVAPALNKPKKPLSSSSAAPQRPISTQRTAAAP---- 173
Query: 440 PSAQPTQQSKVSPAGSHNSVTINGGDQAEVGKLRKAIESLTLQSEDDKTTIDNLMRERDF 619
K P + + GD E +L + + L K T+++L +ERDF
Sbjct: 174 ---------KAGPGVVRKNPGVGNGDD-EAAELMQQVNVL-------KLTVEDLEKERDF 216
Query: 620 YFNKLRDIEVLCQE-DGEKNPVIAKVLEILYATEEGFAAPD-----DEPEEF 757
YF KLR+IE++CQE +GE +PV+ ++++ILYAT+EGF PD +E EE+
Sbjct: 217 YFGKLRNIELICQENEGENDPVLQRIVDILYATDEGFVIPDEGGPQEEQEEY 268
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,107,313
Number of Sequences: 369166
Number of extensions: 1560406
Number of successful extensions: 5900
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5521
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5846
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)