Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_F11
(553 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P37397|CNN3_RAT Calponin-3 (Calponin, acidic isoform) (C... 60 5e-09
sp|Q15417|CNN3_HUMAN Calponin-3 (Calponin, acidic isoform) 59 6e-09
sp|Q9DAW9|CNN3_MOUSE Calponin-3 (Calponin, acidic isoform) 59 6e-09
sp|Q08094|CNN2_PIG Calponin-2 (Calponin H2, smooth muscle) ... 57 3e-08
sp|Q99439|CNN2_HUMAN Calponin-2 (Calponin H2, smooth muscle... 57 3e-08
sp|Q08093|CNN2_MOUSE Calponin-2 (Calponin H2, smooth muscle... 55 1e-07
sp|P26932|CNN1_CHICK Calponin-1 (Calponin, smooth muscle) 55 1e-07
sp|Q08290|CNN1_RAT Calponin-1 (Calponin H1, smooth muscle) ... 49 8e-06
sp|Q08092|CNN1_PIG Calponin-1 (Calponin H1, smooth muscle) ... 49 8e-06
sp|P51911|CNN1_HUMAN Calponin-1 (Calponin H1, smooth muscle... 49 8e-06
>sp|P37397|CNN3_RAT Calponin-3 (Calponin, acidic isoform) (Calponin, non-muscle
isoform)
Length = 330
Score = 59.7 bits (143), Expect = 5e-09
Identities = 46/103 (44%), Positives = 57/103 (55%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q GM G R H+ D K Q+ ISLQ GTN GA+Q GM GT+R I D
Sbjct: 171 NKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMSAPGTRRDIYD 230
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS-FGAQRHIND 305
L+P NS+ ISLQMG + +VA+Q GMS +G R + D
Sbjct: 231 QKLTLQPVDNST--ISLQMGTN--KVASQKGMSVYGLGRQVYD 269
Score = 42.7 bits (99), Expect = 6e-04
Identities = 33/76 (43%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Frame = +3
Query: 84 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 260
K QS+I LQ GTN A+Q GM GT+RH+ D + + + ISLQMG + + A
Sbjct: 158 KAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTT-ISLQMGTN--KGA 214
Query: 261 NQSGMSF-GAQRHIND 305
+Q+GMS G +R I D
Sbjct: 215 SQAGMSAPGTRRDIYD 230
>sp|Q15417|CNN3_HUMAN Calponin-3 (Calponin, acidic isoform)
Length = 329
Score = 59.3 bits (142), Expect = 6e-09
Identities = 46/103 (44%), Positives = 57/103 (55%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q GM G R H+ D K Q+ ISLQ GTN GA+Q GM GT+R I D
Sbjct: 171 NKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYD 230
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS-FGAQRHIND 305
L+P NS+ ISLQMG + +VA+Q GMS +G R + D
Sbjct: 231 QKLTLQPVDNST--ISLQMGTN--KVASQKGMSVYGLGRQVYD 269
Score = 40.8 bits (94), Expect = 0.002
Identities = 32/76 (42%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Frame = +3
Query: 84 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 260
K QS+I LQ GTN A+Q GM GT+RH+ D + + + ISLQMG + + A
Sbjct: 158 KAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTT-ISLQMGTN--KGA 214
Query: 261 NQSGM-SFGAQRHIND 305
+Q+GM + G +R I D
Sbjct: 215 SQAGMLAPGTRRDIYD 230
>sp|Q9DAW9|CNN3_MOUSE Calponin-3 (Calponin, acidic isoform)
Length = 330
Score = 59.3 bits (142), Expect = 6e-09
Identities = 46/103 (44%), Positives = 57/103 (55%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q GM G R H+ D K Q+ ISLQ GTN GA+Q GM GT+R I D
Sbjct: 171 NKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYD 230
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS-FGAQRHIND 305
L+P NS+ ISLQMG + +VA+Q GMS +G R + D
Sbjct: 231 QKLTLQPVDNST--ISLQMGTN--KVASQKGMSVYGLGRQVYD 269
Score = 40.8 bits (94), Expect = 0.002
Identities = 32/76 (42%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Frame = +3
Query: 84 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 260
K QS+I LQ GTN A+Q GM GT+RH+ D + + + ISLQMG + + A
Sbjct: 158 KAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTT-ISLQMGTN--KGA 214
Query: 261 NQSGM-SFGAQRHIND 305
+Q+GM + G +R I D
Sbjct: 215 SQAGMLAPGTRRDIYD 230
>sp|Q08094|CNN2_PIG Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Length = 296
Score = 57.0 bits (136), Expect = 3e-08
Identities = 46/102 (45%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q GM G R H+ D K S ISLQ GTN A+Q GM GT+RHI D
Sbjct: 173 NKCASQSGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYD 232
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMSFGAQRHIND 305
G + NSS +SLQMG + ANQSG FG R I D
Sbjct: 233 TKLGTDKCDNSS--MSLQMG--YTQGANQSGQVFGLGRQIYD 270
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/77 (44%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Frame = +3
Query: 84 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 260
K Q +I LQ GTN A+Q+GM GT+RH+ D + P + S ISLQMG + + A
Sbjct: 160 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHST-ISLQMGTN--KCA 216
Query: 261 NQSGMSF-GAQRHINDS 308
+Q GM+ G +RHI D+
Sbjct: 217 SQVGMTAPGTRRHIYDT 233
>sp|Q99439|CNN2_HUMAN Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Length = 309
Score = 57.0 bits (136), Expect = 3e-08
Identities = 46/102 (45%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q GM G R H+ D K S ISLQ GTN A+Q GM GT+RHI D
Sbjct: 173 NKCASQSGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYD 232
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMSFGAQRHIND 305
G + NSS +SLQMG + ANQSG FG R I D
Sbjct: 233 TKLGTDKCDNSS--MSLQMG--YTQGANQSGQVFGLGRQIYD 270
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/77 (44%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Frame = +3
Query: 84 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 260
K Q +I LQ GTN A+Q+GM GT+RH+ D + P + S ISLQMG + + A
Sbjct: 160 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHST-ISLQMGTN--KCA 216
Query: 261 NQSGMSF-GAQRHINDS 308
+Q GM+ G +RHI D+
Sbjct: 217 SQVGMTAPGTRRHIYDT 233
>sp|Q08093|CNN2_MOUSE Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)
Length = 305
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/102 (44%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q GM G R H+ D K ISLQ GTN A+Q GM GT+RHI D
Sbjct: 173 NKCASQSGMTAYGTRRHLYDPKNHILPPMDHCTISLQMGTNKCASQVGMTAPGTRRHIYD 232
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMSFGAQRHIND 305
G + NSS +SLQMG + ANQSG FG R I D
Sbjct: 233 TKLGTDKCDNSS--MSLQMG--YTQGANQSGQVFGLGRQIYD 270
Score = 45.4 bits (106), Expect = 9e-05
Identities = 33/77 (42%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Frame = +3
Query: 84 KEAQSIISLQYGTNLGANQNGM-RIGTQRHITDISCGLEPNKNSSNFISLQMGPSMKEVA 260
K Q +I LQ GTN A+Q+GM GT+RH+ D + P + ISLQMG + + A
Sbjct: 160 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHCT-ISLQMGTN--KCA 216
Query: 261 NQSGMSF-GAQRHINDS 308
+Q GM+ G +RHI D+
Sbjct: 217 SQVGMTAPGTRRHIYDT 233
>sp|P26932|CNN1_CHICK Calponin-1 (Calponin, smooth muscle)
Length = 292
Score = 54.7 bits (130), Expect = 1e-07
Identities = 42/103 (40%), Positives = 57/103 (55%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q+GM G R H+ D K Q+ ISLQ GTN GA+Q GM GT+R I +
Sbjct: 171 NKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFE 230
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS-FGAQRHIND 305
S G+E + +N I LQMG + + A+Q GM+ +G R + D
Sbjct: 231 PSLGME--RCDTNIIGLQMGSN--KGASQQGMTVYGLPRQVYD 269
>sp|Q08290|CNN1_RAT Calponin-1 (Calponin H1, smooth muscle) (Basic calponin)
Length = 297
Score = 48.9 bits (115), Expect = 8e-06
Identities = 40/103 (38%), Positives = 55/103 (53%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q+GM G R H+ D K Q+ ISLQ GTN GA+Q GM GT+R I +
Sbjct: 171 NKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFE 230
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS-FGAQRHIND 305
G+E + +SLQMG + + A+Q GM+ +G R + D
Sbjct: 231 PGLGMEHCDTLN--VSLQMGSN--KGASQRGMTVYGLPRQVYD 269
>sp|Q08092|CNN1_PIG Calponin-1 (Calponin H1, smooth muscle) (Basic calponin)
Length = 297
Score = 48.9 bits (115), Expect = 8e-06
Identities = 40/103 (38%), Positives = 55/103 (53%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q+GM G R H+ D K Q+ ISLQ GTN GA+Q GM GT+R I +
Sbjct: 171 NKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFE 230
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS-FGAQRHIND 305
G+E + +SLQMG + + A+Q GM+ +G R + D
Sbjct: 231 PGLGMEHCDTLN--VSLQMGSN--KGASQRGMTVYGLPRQVYD 269
>sp|P51911|CNN1_HUMAN Calponin-1 (Calponin H1, smooth muscle) (Basic calponin)
Length = 297
Score = 48.9 bits (115), Expect = 8e-06
Identities = 40/103 (38%), Positives = 55/103 (53%), Gaps = 3/103 (2%)
Frame = +3
Query: 6 NSARGQKGMVMGGVR-HVSDIKCLESNKEAQSIISLQYGTNLGANQNGMRI-GTQRHITD 179
N Q+GM G R H+ D K Q+ ISLQ GTN GA+Q GM GT+R I +
Sbjct: 171 NKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFE 230
Query: 180 ISCGLEPNKNSSNFISLQMGPSMKEVANQSGMS-FGAQRHIND 305
G+E + +SLQMG + + A+Q GM+ +G R + D
Sbjct: 231 PGLGMEHCDTLN--VSLQMGSN--KGASQRGMTVYGLPRQVYD 269
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,387,558
Number of Sequences: 369166
Number of extensions: 1372298
Number of successful extensions: 2970
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2897
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2960
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3882260660
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)