Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_010_F05 (585 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q91X78|SPFH1_MOUSE SPFH domain protein 1 precursor (KE04... 138 1e-32 sp|O75477|SPFH1_HUMAN SPFH domain protein 1 precursor (Prot... 136 3e-32 sp|Q5RCJ9|SPFH1_PONPY SPFH domain protein 1 precursor 136 3e-32 sp|O94905|SPFH2_HUMAN SPFH domain protein 2 precursor >gi|6... 135 1e-31 sp|Q8BFZ9|SPFH2_MOUSE SPFH domain protein 2 precursor 134 2e-31 sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle 39 0.007 sp|O13127|FLOT1_CARAU Flotillin-1 (Reggie-2) (REG-2) 35 0.11 sp|P23607|ZFA_MOUSE Zinc finger autosomal protein 34 0.23 sp|O61491|FLOT1_DROME Flotillin-1 34 0.31 sp|P26038|MOES_HUMAN Moesin (Membrane-organizing extension ... 33 0.40
>sp|Q91X78|SPFH1_MOUSE SPFH domain protein 1 precursor (KE04 protein homolog) Length = 346 Score = 138 bits (347), Expect = 1e-32 Identities = 72/130 (55%), Positives = 102/130 (78%), Gaps = 5/130 (3%) Frame = +2 Query: 2 IASERQRVVEKEAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISRIEDAARTSRI 181 IA+++Q+VVEKEAETER RA+IEAEK+AQV++I +Q K+ EKE+E IS IEDAA +R Sbjct: 195 IAAQKQKVVEKEAETERKRAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLARE 254 Query: 182 KSESDAEFYRAKQEAEANKVKLTQEYLEMIRLLSIANNTKIYFGNSIPQMFLDSS----- 346 K+++DAE+Y A + A +NK KLT EYLE+ + +IA+N+KIYFG++IP MF+DSS Sbjct: 255 KAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPSMFVDSSCALKY 314 Query: 347 NSGQTNQDYS 376 + G+T ++ S Sbjct: 315 SDGRTGREDS 324
>sp|O75477|SPFH1_HUMAN SPFH domain protein 1 precursor (Protein KE04) Length = 346 Score = 136 bits (343), Expect = 3e-32 Identities = 68/115 (59%), Positives = 95/115 (82%) Frame = +2 Query: 2 IASERQRVVEKEAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISRIEDAARTSRI 181 IA+++Q+VVEKEAETER +A+IEAEK+AQV++I +Q K+ EKE+E IS IEDAA +R Sbjct: 195 IAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLARE 254 Query: 182 KSESDAEFYRAKQEAEANKVKLTQEYLEMIRLLSIANNTKIYFGNSIPQMFLDSS 346 K+++DAE+Y A + A +NK KLT EYLE+ + +IA+N+KIYFG++IP MF+DSS Sbjct: 255 KAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSS 309
>sp|Q5RCJ9|SPFH1_PONPY SPFH domain protein 1 precursor Length = 346 Score = 136 bits (343), Expect = 3e-32 Identities = 68/115 (59%), Positives = 95/115 (82%) Frame = +2 Query: 2 IASERQRVVEKEAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISRIEDAARTSRI 181 IA+++Q+VVEKEAETER +A+IEAEK+AQV++I +Q K+ EKE+E IS IEDAA +R Sbjct: 195 IAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLARE 254 Query: 182 KSESDAEFYRAKQEAEANKVKLTQEYLEMIRLLSIANNTKIYFGNSIPQMFLDSS 346 K+++DAE+Y A + A +NK KLT EYLE+ + +IA+N+KIYFG++IP MF+DSS Sbjct: 255 KAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSS 309
>sp|O94905|SPFH2_HUMAN SPFH domain protein 2 precursor sp|Q5R7C5|SPFH2_PONPY SPFH domain protein 2 precursor Length = 339 Score = 135 bits (339), Expect = 1e-31 Identities = 68/117 (58%), Positives = 94/117 (80%) Frame = +2 Query: 2 IASERQRVVEKEAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISRIEDAARTSRI 181 IA+++Q+VVEKEAETER +A+IEAEK+AQV+ I + K+ EKE+E IS IEDAA +R Sbjct: 195 IAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLARE 254 Query: 182 KSESDAEFYRAKQEAEANKVKLTQEYLEMIRLLSIANNTKIYFGNSIPQMFLDSSNS 352 K+++DAE Y A + AEANK+KLT EYL++++ +IA+N+KIYFG IP MF+DS+ S Sbjct: 255 KAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGS 311
>sp|Q8BFZ9|SPFH2_MOUSE SPFH domain protein 2 precursor Length = 340 Score = 134 bits (336), Expect = 2e-31 Identities = 72/138 (52%), Positives = 101/138 (73%), Gaps = 1/138 (0%) Frame = +2 Query: 2 IASERQRVVEKEAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISRIEDAARTSRI 181 IA+++Q+VVEKEAETER +A+IEAEK+AQV+ I + K+ EKE+E IS IEDAA +R Sbjct: 195 IAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEKKISEIEDAAFLARE 254 Query: 182 KSESDAEFYRAKQEAEANKVKLTQEYLEMIRLLSIANNTKIYFGNSIPQMFLDSSNS-GQ 358 K+++DAE Y A + AEANK+KLT EYL++++ +IA+N+KIYFG IP MF+DS+ G+ Sbjct: 255 KAKADAECYTALKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKDIPNMFMDSAGGLGK 314 Query: 359 TNQDYSTSTPGIKLPNLP 412 + S G L + P Sbjct: 315 QFEGLSDDKLGFGLEDEP 332
>sp|P08799|MYS2_DICDI Myosin II heavy chain, non muscle Length = 2116 Score = 39.3 bits (90), Expect = 0.007 Identities = 41/122 (33%), Positives = 53/122 (43%) Frame = +2 Query: 35 EAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISRIEDAARTSRIKSESDAEFYRA 214 E E RL+ +EAE+LA+ S + Q K E + +ED KS AE A Sbjct: 1177 EGEVARLQGELEAEQLAK-SNVEKQKKKVELD-------LED-------KSAQLAEETAA 1221 Query: 215 KQEAEANKVKLTQEYLEMIRLLSIANNTKIYFGNSIPQMFLDSSNSGQTNQDYSTSTPGI 394 KQ + K KL QE E+ LS ANN + NS TN+ TS + Sbjct: 1222 KQALDKLKKKLEQELSEVQTQLSEANNKNV--------------NSDSTNKHLETSFNNL 1267 Query: 395 KL 400 KL Sbjct: 1268 KL 1269
>sp|O13127|FLOT1_CARAU Flotillin-1 (Reggie-2) (REG-2) Length = 423 Score = 35.4 bits (80), Expect = 0.11 Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Frame = +2 Query: 23 VVEKEAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISRIEDAARTSRIKSE---- 190 V K+AE+E + A+ Q+ Q+ + E+ ++ + E A + ++++ Sbjct: 227 VCTKKAESEMAYQLQVAKTKQQIEEEKMQVMVVERSQQIMLQEQEIARKEKELEAQVMKP 286 Query: 191 SDAEFYRAKQEAEANKVKLTQE 256 +DAE YR ++ AEA +++L E Sbjct: 287 ADAERYRLEKLAEAERLQLIME 308
>sp|P23607|ZFA_MOUSE Zinc finger autosomal protein Length = 742 Score = 34.3 bits (77), Expect = 0.23 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Frame = +2 Query: 23 VVEKEAETERLRAIIEAEKLAQVSR---IHWQMKITEKESELNISRIEDAARTSRIKSES 193 +VE E E E +++ V R ++ + +++E ELN++ I D I E Sbjct: 215 IVESEPENELGVELLDPNNSICVpreKMVYMAVNNSQQEEELNVTEIADEIYMEVIVGEE 274 Query: 194 DAEFYRAKQEAEANKVK 244 DA +Q+ E NK+K Sbjct: 275 DATASEHEQQVEDNKMK 291
>sp|O61491|FLOT1_DROME Flotillin-1 Length = 426 Score = 33.9 bits (76), Expect = 0.31 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 3/93 (3%) Frame = +2 Query: 2 IASERQRVVEKEAETER-LRAIIEAEK--LAQVSRIHWQMKITEKESELNISRIEDAART 172 IA + Q ++ +E E E +R EAEK + +++ + Q + E E+E RI A Sbjct: 268 IAVQEQEIMRRERELEATIRRPAEAEKFRMEKLAEANKQRVVMEAEAEAESIRIRGEAEA 327 Query: 173 SRIKSESDAEFYRAKQEAEANKVKLTQEYLEMI 271 I +++ AE + +AEA + +EM+ Sbjct: 328 FAIAAKAKAEAEQMAMKAEAYREYREAAMVEML 360
>sp|P26038|MOES_HUMAN Moesin (Membrane-organizing extension spike protein) Length = 577 Score = 33.5 bits (75), Expect = 0.40 Identities = 36/94 (38%), Positives = 44/94 (46%), Gaps = 14/94 (14%) Frame = +2 Query: 35 EAETERLRAIIEAEKLAQVSRIHWQMKITEKESELNISR----------IEDAARTSRIK 184 E E ER RA EAEKLA+ Q KE+ L SR +E A T+RI Sbjct: 374 ELEQERKRAQSEAEKLAK----ERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARI- 428 Query: 185 SESDAEFYRAKQEAEA----NKVKLTQEYLEMIR 274 S E R K+E+EA K ++ QE LE R Sbjct: 429 --SQLEMARQKKESEAVEWQQKAQMVQEDLEKTR 460
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 57,599,430 Number of Sequences: 369166 Number of extensions: 1068549 Number of successful extensions: 3073 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2954 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3060 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4357244645 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)