Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_E15
(521 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P49312|ROA1_MOUSE Heterogeneous nuclear ribonucleoprotei... 60 4e-09
sp|P04256|ROA1_RAT Heterogeneous nuclear ribonucleoprotein ... 58 2e-08
sp|Q28521|ROA1_MACMU Heterogeneous nuclear ribonucleoprotei... 57 3e-08
sp|P51992|RO32_XENLA Heterogeneous nuclear ribonucleoprotei... 55 1e-07
sp|P22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoprotei... 54 2e-07
sp|P51968|RO31_XENLA Heterogeneous nuclear ribonucleoprotei... 54 2e-07
sp|O88569|ROA2_MOUSE Heterogeneous nuclear ribonucleoprotei... 54 2e-07
sp|P51989|RO21_XENLA Heterogeneous nuclear ribonucleoprotei... 52 7e-07
sp|P09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotei... 52 1e-06
sp|P51991|ROA3_HUMAN Heterogeneous nuclear ribonucleoprotei... 51 1e-06
>sp|P49312|ROA1_MOUSE Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1) (HDP-1) (Topoisomerase-inhibitor suppressed)
Length = 320
Score = 59.7 bits (143), Expect = 4e-09
Identities = 43/139 (30%), Positives = 62/139 (44%), Gaps = 25/139 (17%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEE----ARSLKAKESMSTIGKSKFPAMSQ 169
+DD+D VDKI++ K H ++ CEV+KALSK+E + S + + G +
Sbjct: 153 FDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGG 212
Query: 170 SN-------------------GGMMGFMGDMRNDISNRYDNFGYQDYDDRFGRYPNQGYS 292
++ GG G GD N N NFG + FG Y NQ +
Sbjct: 213 NDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSN 272
Query: 293 GGPVR-GNMSYRNQ-PYSG 343
GP++ GN R+ PY G
Sbjct: 273 FGPMKGGNFGGRSSGPYGG 291
>sp|P04256|ROA1_RAT Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1) (HDP)
Length = 320
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/139 (30%), Positives = 61/139 (43%), Gaps = 25/139 (17%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEE----ARSLKAKESMSTIGKSKFPAMSQ 169
+DD+D VDKI++ K H ++ CEV+KAL K+E + S + + G +
Sbjct: 153 FDDHDSVDKIVIQKYHTVNGHNCEVRKALCKQEMASASSSQRGRSGSGNFGGGRGGGFGG 212
Query: 170 SN-------------------GGMMGFMGDMRNDISNRYDNFGYQDYDDRFGRYPNQGYS 292
++ GG G GD N N NFG + FG Y NQ +
Sbjct: 213 NDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSN 272
Query: 293 GGPVR-GNMSYRNQ-PYSG 343
GP++ GN R+ PY G
Sbjct: 273 FGPMKGGNFGGRSSGPYGG 291
>sp|Q28521|ROA1_MACMU Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1)
Length = 320
Score = 57.0 bits (136), Expect = 3e-08
Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 25/139 (17%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEE----ARSLKAKESMSTIGKSKFPAMSQ 169
+DD++ VDKI++ K H ++ CEV+KALSK+E + S + + G +
Sbjct: 153 FDDHNSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGG 212
Query: 170 SN-------------------GGMMGFMGDMRNDISNRYDNFGYQDYDDRFGRYPNQGYS 292
++ GG G GD N N NFG + FG Y NQ +
Sbjct: 213 NDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSN 272
Query: 293 GGPVR-GNMSYRN-QPYSG 343
GP++ GN R+ PY G
Sbjct: 273 FGPMKGGNFGGRSLGPYGG 291
>sp|P51992|RO32_XENLA Heterogeneous nuclear ribonucleoprotein A3 homolog 2 (hnRNP A3(B))
Length = 385
Score = 54.7 bits (130), Expect = 1e-07
Identities = 43/132 (32%), Positives = 54/132 (40%), Gaps = 12/132 (9%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEEARSLKAKESMSTIGKSKFPAMSQSNGG 181
+DD+D VDKI++ K H I+ CEVKKALSK+E ++ A+ G S F + GG
Sbjct: 166 FDDHDTVDKIVVQKYHTINLHNCEVKKALSKQEMQTASAQRGRGG-GGSNFMGRGGNYGG 224
Query: 182 MMGFMGDMRNDISNRYDNFGYQDYDDRFGRYPNQG------------YSGGPVRGNMSYR 325
G G + GY R G Y G Y GGP G Y
Sbjct: 225 GDGGGGGNFGRGGGFGNRGGYGGGGGRGGGYGGGGDGYNGFGGDGGNYGGGPGYGGRGYG 284
Query: 326 NQPYSGRMRRDY 361
P G Y
Sbjct: 285 GSPGYGNQGGGY 296
>sp|P22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP
B1)
Length = 353
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEEARSLKAKESMSTIGKSKFPAMSQSNGG 181
+DD+DPVDKI+L K H I+ EV+KALS++E + +++ S G+ S GG
Sbjct: 160 FDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRS----GRGGNFGFGDSRGG 215
Query: 182 MMGFMGDMRNDISNRYDNFGY-QDYDDRFGRYPNQGYSGGPVRGN 313
F ++ D +G + + D + GY GGP GN
Sbjct: 216 GGNFGPGPGSNFRGGSDGYGSGRGFGDGY-----NGYGGGPGGGN 255
>sp|P51968|RO31_XENLA Heterogeneous nuclear ribonucleoprotein A3 homolog 1 (hnRNP A3(A))
Length = 373
Score = 53.9 bits (128), Expect = 2e-07
Identities = 43/132 (32%), Positives = 55/132 (41%), Gaps = 12/132 (9%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEEARSLKAKESMSTIGKSKFPAMSQSNGG 181
+DD+D VDKI++ K H I+ CEVKKALSK+E ++ A+ G S F + GG
Sbjct: 166 FDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQTASAQRGRGG-GGSNFMGRGGNYGG 224
Query: 182 MMG--FMGDMRNDISNR--------YDNFGYQDYDDRFGRYPNQG--YSGGPVRGNMSYR 325
G F NR GY D + + G Y GGP G Y
Sbjct: 225 GDGGNFGRGGGGGFGNRGGYGGGGGRGGGGYGGGGDGYNGFGGDGGNYGGGPGYGGRGYG 284
Query: 326 NQPYSGRMRRDY 361
P G Y
Sbjct: 285 GSPGYGNQGGGY 296
>sp|O88569|ROA2_MOUSE Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP
B1)
Length = 341
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEEARSLKAKESMSTIGKSKFPAMSQSNGG 181
+DD+DPVDKI+L K H I+ EV+KALS++E + +++ S G+ S GG
Sbjct: 148 FDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRS----GRGGNFGFGDSRGG 203
Query: 182 MMGFMGDMRNDISNRYDNFGY-QDYDDRFGRYPNQGYSGGPVRGN 313
F ++ D +G + + D + GY GGP GN
Sbjct: 204 GGNFGPGPGSNFRGGSDGYGSGRGFGDGY-----NGYGGGPGGGN 243
>sp|P51989|RO21_XENLA Heterogeneous nuclear ribonucleoprotein A2 homolog 1 (hnRNP A2(A))
Length = 346
Score = 52.4 bits (124), Expect = 7e-07
Identities = 38/118 (32%), Positives = 51/118 (43%), Gaps = 4/118 (3%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEEARSLKAKESMSTIGKSKFPAMSQSNGG 181
+DD+DPVDKI+L K H I+ EV+KALSK+E
Sbjct: 148 FDDHDPVDKIVLQKYHTINGHNAEVRKALSKQE--------------------------- 180
Query: 182 MMGFMGDMRNDISNRYDNFGYQDY--DDRFGRYPNQGYSGGP--VRGNMSYRNQPYSG 343
M D++N +NR NFG+ D FG P + GG G Y + Y+G
Sbjct: 181 ----MQDVQNTRNNRGGNFGFGDSRGGGNFGSGPGGNFRGGSDGYGGGRGYGDNGYNG 234
Score = 30.0 bits (66), Expect = 3.5
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 11/67 (16%)
Frame = +2
Query: 176 GGMMGFMGDMRNDISNRYDNFGYQDYD-----DRFGRYPNQGYSGGPVR------GNMSY 322
GG G+ G+ YDN+G +Y + FG Y Q + GP++ GN S
Sbjct: 259 GGGAGY-GNQGGGYGGGYDNYGGGNYGGGGNYNDFGNYNQQSSNYGPMKSGGNFGGNRSM 317
Query: 323 RNQPYSG 343
PY G
Sbjct: 318 GGGPYGG 324
>sp|P09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1)
Length = 372
Score = 51.6 bits (122), Expect = 1e-06
Identities = 40/112 (35%), Positives = 51/112 (45%), Gaps = 13/112 (11%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEEARSLKAKESMSTIGKSKFPAMSQSNGG 181
+DD+D VDKI++ K H ++ CEV+KALSK+E A S S G+S GG
Sbjct: 153 FDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQE----MASASSSQRGRSGSGNFGGGRGG 208
Query: 182 MMGFMGDMRNDISNRYDNF-------------GYQDYDDRFGRYPNQGYSGG 298
GF G ND R NF GY D + + N G GG
Sbjct: 209 --GFGG---NDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGG 255
Score = 31.2 bits (69), Expect = 1.6
Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Frame = +2
Query: 164 SQSNGGMMGFMGDMRNDISNRYDNFGYQDYDDRFGRYPNQGYSGGPVR-GNMSYRNQ-PY 337
S +NGG GF G + NFG + FG Y NQ + GP++ GN R+ PY
Sbjct: 289 SYNNGGGRGFGGGSGS-------NFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPY 341
Query: 338 SG 343
G
Sbjct: 342 GG 343
>sp|P51991|ROA3_HUMAN Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
Length = 378
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/114 (34%), Positives = 51/114 (44%)
Frame = +2
Query: 2 YDDYDPVDKILLLKPHYIDNKRCEVKKALSKEEARSLKAKESMSTIGKSKFPAMSQSNGG 181
+DD+D VDKI++ K H I+ CEVKKALSK+E +S ++ GG
Sbjct: 174 FDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRG--------------RGGG 219
Query: 182 MMGFMGDMRNDISNRYDNFGYQDYDDRFGRYPNQGYSGGPVRGNMSYRNQPYSG 343
FMG N NFG FG G GG RG+ + Y+G
Sbjct: 220 SGNFMGRGGN-FGGGGGNFG---RGGNFGGRGGYGGGGGGSRGSYGGGDGGYNG 269
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,328,091
Number of Sequences: 369166
Number of extensions: 849544
Number of successful extensions: 2252
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2163
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2244
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3452909250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)