Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_E04
(852 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P70453|PDE7A_MOUSE High-affinity cAMP-specific 3',5'-cyc... 254 2e-67
sp|Q13946|PDE7A_HUMAN High-affinity cAMP-specific 3',5'-cyc... 253 6e-67
sp|O08593|PDE7A_RAT High-affinity cAMP-specific 3',5'-cycli... 252 1e-66
sp|Q9NP56|PDE7B_HUMAN cAMP-specific 3',5'-cyclic phosphodie... 234 2e-61
sp|Q9QXQ1|PDE7B_MOUSE cAMP-specific 3',5'-cyclic phosphodie... 234 3e-61
sp|O88502|PDE8A_MOUSE High-affinity cAMP-specific and IBMX-... 166 6e-41
sp|Q01063|PDE4D_MOUSE cAMP-specific 3',5'-cyclic phosphodie... 160 4e-39
sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodie... 160 4e-39
sp|Q9N2V9|PDE6_CAEEL Probable 3',5'-cyclic phosphodiesteras... 159 7e-39
sp|P14270|PDE4D_RAT cAMP-specific 3',5'-cyclic phosphodiest... 159 7e-39
>sp|P70453|PDE7A_MOUSE High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (P2A)
Length = 456
Score = 254 bits (650), Expect = 2e-67
Identities = 123/276 (44%), Positives = 180/276 (65%)
Frame = +2
Query: 8 FKIDYLKFLHTLIL*ALLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFM 187
F +D +K L++ ++ +YH +NPYHNA+HAADVTQAMHCY+ + K+ + +D +
Sbjct: 161 FHLDMVKLRRFLVM---IQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDIL 217
Query: 188 VSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETRVFHHFT 367
+SL+ A HD+DHPGVNQ FL KTN+YL+ YK SVLENHH+R A+ +L E+ +F H
Sbjct: 218 LSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLP 277
Query: 368 SKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIELNIGIKEAFTKENKILIMQMALKCA 547
+ E++ ++ LI+ATDI+RQNEYL F + L+ G ++ L++QMALKCA
Sbjct: 278 LESRQEMEAQIGALILATDISRQNEYLSLFRS--HLDKGDLHLDDGRHRHLVLQMALKCA 335
Query: 548 DICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLV 727
DICNPCR W ++ W+ ++ EFF QGD E++ +L ++P DR + +Q GF+ +LV
Sbjct: 336 DICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLV 395
Query: 728 RPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQ 835
PLF +W F TRLS+ M+ + N W+ Q Q
Sbjct: 396 EPLFTEWARFSATRLSQTMLGHVGLNKASWKGLQRQ 431
>sp|Q13946|PDE7A_HUMAN High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(HCP1) (TM22)
Length = 482
Score = 253 bits (645), Expect = 6e-67
Identities = 120/276 (43%), Positives = 181/276 (65%)
Frame = +2
Query: 8 FKIDYLKFLHTLIL*ALLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFM 187
F +D +K L++ ++ +YH +NPYHNA+HAADVTQAMHCY+ + K+ + +D +
Sbjct: 187 FHLDMMKLRRFLVM---IQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDIL 243
Query: 188 VSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETRVFHHFT 367
+SL+ A HD+DHPGVNQ FL KTN+YL+ YK SVLENHH+R A+ +L E+ +F H
Sbjct: 244 LSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLP 303
Query: 368 SKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIELNIGIKEAFTKENKILIMQMALKCA 547
+ +++ ++ LI+ATDI+RQNEYL F + ++ E ++ L++QMALKCA
Sbjct: 304 LESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLE--DTRHRHLVLQMALKCA 361
Query: 548 DICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLV 727
DICNPCR W ++ W+ ++ EFF QGD E++ +L ++P DR+ + +Q GF+ +LV
Sbjct: 362 DICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLV 421
Query: 728 RPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQ 835
PLF +W F TRLS+ M+ + N W+ Q +
Sbjct: 422 EPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQRE 457
>sp|O08593|PDE7A_RAT High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Rolipram-insensitive phosphodiesterase type 7)
Length = 426
Score = 252 bits (643), Expect = 1e-66
Identities = 122/276 (44%), Positives = 179/276 (64%)
Frame = +2
Query: 8 FKIDYLKFLHTLIL*ALLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFM 187
F +D +K L++ ++ +YH +NPYHNA+HAADVTQAMHCY+ + K+ + +D +
Sbjct: 131 FHLDMVKLRRFLVM---IQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDIL 187
Query: 188 VSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETRVFHHFT 367
+SL+ A HD+DHPGVNQ FL KTN+YL+ YK SVLENHH+R A+ +L E+ +F H
Sbjct: 188 LSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLP 247
Query: 368 SKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIELNIGIKEAFTKENKILIMQMALKCA 547
+ E++ ++ LI+ATDI+RQNEYL F + L+ G ++ L++QMALKCA
Sbjct: 248 LESRHEMEAQIGALILATDISRQNEYLSLFRS--HLDKGDLHLDDGRHRHLVLQMALKCA 305
Query: 548 DICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLV 727
DICNPCR W ++ W+ ++ EFF QGD E++ +L ++P DR + +Q GF+ +L
Sbjct: 306 DICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLQ 365
Query: 728 RPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQ 835
PLF +W F TRLS+ M+ + N W+ Q Q
Sbjct: 366 EPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQ 401
>sp|Q9NP56|PDE7B_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 7B
Length = 450
Score = 234 bits (598), Expect = 2e-61
Identities = 112/273 (41%), Positives = 179/273 (65%), Gaps = 2/273 (0%)
Frame = +2
Query: 8 FKIDYLKFLHTLIL*ALLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFM 187
FK+D + LH ++ +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+ + D M
Sbjct: 148 FKLDMVT-LHRFLV--MVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIM 204
Query: 188 VSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETRVFHHFT 367
+ LL A HDVDHPGVNQ FL KTN++L+ Y+ SVLENHH+R + +L E+R+ H
Sbjct: 205 LGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLP 264
Query: 368 SKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIELNIGIKEAFTKENKILIMQMALKC 544
+ +++ ++ LI+ATDI RQNE+L + + ++ +++A +++ ++Q+ALKC
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDA---QDRHFMLQIALKC 321
Query: 545 ADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFL 724
ADICNPCR W ++ W+ + EF+RQG+ E++ L ++P ++ + P +Q GF+ ++
Sbjct: 322 ADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFMSYI 381
Query: 725 VRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE 820
V PLF +W F + LSE M+ L N +W+
Sbjct: 382 VEPLFREWAHFTGNSTLSENMLGHLAHNKAQWK 414
>sp|Q9QXQ1|PDE7B_MOUSE cAMP-specific 3',5'-cyclic phosphodiesterase 7B
Length = 446
Score = 234 bits (596), Expect = 3e-61
Identities = 116/280 (41%), Positives = 181/280 (64%), Gaps = 4/280 (1%)
Frame = +2
Query: 8 FKIDYLKFLHTLIL*ALLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFM 187
FK+D + LH ++ +++ +YH NPYHNA+HAADVTQAMHCY+ + K+ + D M
Sbjct: 148 FKLDMVT-LHRFLV--MVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIM 204
Query: 188 VSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETRVFHHFT 367
+ LL A HDVDHPGVNQ FL KTN++L+ Y+ SVLENHH+R + +L E+R+ H
Sbjct: 205 LGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLP 264
Query: 368 SKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIELNIGIKEAFTK--ENKILIMQMALK 541
+ +++ ++ LI+ATDI RQNE+L + ++ ++ K+ + +++ ++Q+ALK
Sbjct: 265 KEMTQDIEQQLGSLILATDINRQNEFLTR----LKAHLHNKDLRLENVQDRHFMLQIALK 320
Query: 542 CADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRF 721
CADICNPCR W ++ W+ + EF+RQGD E++ L ++P ++ + P +Q GF+ +
Sbjct: 321 CADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTY 380
Query: 722 LVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE-LKQNQ 835
+V PLF +W F + LSE M+ L N +W+ L NQ
Sbjct: 381 IVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQ 420
>sp|O88502|PDE8A_MOUSE High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic
phosphodiesterase 8A (MMPDE8)
Length = 823
Score = 166 bits (421), Expect = 6e-41
Identities = 88/273 (32%), Positives = 146/273 (53%), Gaps = 18/273 (6%)
Frame = +2
Query: 56 LLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGV 235
++E+NYH NPYHN+ HAADV A ++S KI++ + + D + +L+ A HDVDHPG
Sbjct: 539 MIESNYHSSNPYHNSTHAADVLHATAYFLSRDKIKETLDRIDEVAALIAATVHDVDHPGR 598
Query: 236 NQAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHET---RVFHHFTSKQWGELQYRMYK 406
+FL N L+ Y +VLE+HH +A + E +F + L+ +
Sbjct: 599 TNSFLCNAGNQLAVLYNDTAVLESHHVALAFQLTLENDQCNIFKQMERNDYRTLRQSIID 658
Query: 407 LIMATDIARQNEYLDQFTNFIELNIGIKEA--------------FTKENKILIMQMALKC 544
+++AT++ + E++++F N I + +E+ T E++ LI +M +KC
Sbjct: 659 MVLATEMTKHFEHVNKFINSINKPLTAQESEEPDRSLEDIKAMLKTPESRALIKRMMIKC 718
Query: 545 ADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLA-PTMDRYGITKPKVQTGFIRF 721
AD+ NPCR WA IS E+F Q D E++++LP+ P DR + PK Q FI +
Sbjct: 719 ADVSNPCRPLEHCIEWAARISEEYFSQTDEEKQLDLPVVMPVFDRNTCSIPKSQISFIDY 778
Query: 722 LVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE 820
+ +F+ W+ F+ ++Q L+ N W+
Sbjct: 779 FITDMFDAWDAFVDL---PNLMQHLDDNFRYWK 808
>sp|Q01063|PDE4D_MOUSE cAMP-specific 3',5'-cyclic phosphodiesterase 4D (DPDE3)
Length = 747
Score = 160 bits (405), Expect = 4e-39
Identities = 82/255 (32%), Positives = 136/255 (53%), Gaps = 6/255 (2%)
Frame = +2
Query: 59 LENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVN 238
LE++YH YHN +HAADV Q+ H +S + + + ++ + HDVDHPGV+
Sbjct: 390 LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS 449
Query: 239 QAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETR--VFHHFTSKQWGELQYRMYKLI 412
FL TN+ L+ Y SVLENHH + +L E +F + T KQ L+ + ++
Sbjct: 450 NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIV 509
Query: 413 MATDIARQNEYLDQFTNFIE----LNIGIKEAFTKENKILIMQMALKCADICNPCREWRV 580
+ATD+++ L +E + G+ ++I ++Q + CAD+ NP + ++
Sbjct: 510 LATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL 569
Query: 581 AACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM 760
W + I EFFRQGDRER + ++P D++ + K Q GFI ++V PL+ W + +
Sbjct: 570 YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV 629
Query: 761 KTRLSEKMVQQLEQN 805
++ ++ LE N
Sbjct: 630 HPD-AQDILDTLEDN 643
>sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4D (DPDE3) (PDE43)
Length = 809
Score = 160 bits (405), Expect = 4e-39
Identities = 82/255 (32%), Positives = 136/255 (53%), Gaps = 6/255 (2%)
Frame = +2
Query: 59 LENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVN 238
LE++YH YHN +HAADV Q+ H +S + + + ++ + HDVDHPGV+
Sbjct: 451 LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS 510
Query: 239 QAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETR--VFHHFTSKQWGELQYRMYKLI 412
FL TN+ L+ Y SVLENHH + +L E +F + T KQ L+ + ++
Sbjct: 511 NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIV 570
Query: 413 MATDIARQNEYLDQFTNFIE----LNIGIKEAFTKENKILIMQMALKCADICNPCREWRV 580
+ATD+++ L +E + G+ ++I ++Q + CAD+ NP + ++
Sbjct: 571 LATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL 630
Query: 581 AACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM 760
W + I EFFRQGDRER + ++P D++ + K Q GFI ++V PL+ W + +
Sbjct: 631 YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV 690
Query: 761 KTRLSEKMVQQLEQN 805
++ ++ LE N
Sbjct: 691 HPD-AQDILDTLEDN 704
>sp|Q9N2V9|PDE6_CAEEL Probable 3',5'-cyclic phosphodiesterase pde-6
Length = 760
Score = 159 bits (403), Expect = 7e-39
Identities = 95/273 (34%), Positives = 143/273 (52%), Gaps = 5/273 (1%)
Frame = +2
Query: 32 LHTLIL*ALLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMF 211
LH IL +E +YH N YHNA HAADV QA ++ + + + + +LL A
Sbjct: 484 LHRWIL--SIEAHYHAGNTYHNATHAADVLQATSFFLDSPSVAVHVNESHAVAALLAAAV 541
Query: 212 HDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRIA--LSILHETRV--FHHFTSKQW 379
HD+DHPG A+L T L+ Y S+LENHH +A L++ H V F + +++
Sbjct: 542 HDLDHPGRGNAYLINTRQSLAILYNDNSILENHHIALAFQLTLQHNANVNIFSSLSREEF 601
Query: 380 GELQYRMYKLIMATDIARQNEYLDQFTNFIELNIGIKEAFTKENKILIMQMALKCADICN 559
++++ M ++++ATDI+R EYL +F ++ ++ T N + I M +KCADI N
Sbjct: 602 IQMRHAMVEMVLATDISRHFEYLAKFNKMHVTDVPEEQRDT--NSLTICDMLVKCADISN 659
Query: 560 PCREWRVAACWANLISAEFFRQGDRERRMNLPLA-PTMDRYGITKPKVQTGFIRFLVRPL 736
P REW + WA+ I E+F Q E+ LP+ DR P Q GFI R
Sbjct: 660 PAREWGLCQRWAHRIVEEYFEQTREEKEKGLPVTMEVFDRNTCNVPITQCGFIDMFAREA 719
Query: 737 FNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQ 835
F + EF K ++ QLE N +W++ +Q
Sbjct: 720 FATFTEFAKL---GELSDQLESNYEKWKVMTSQ 749
>sp|P14270|PDE4D_RAT cAMP-specific 3',5'-cyclic phosphodiesterase 4D (DPDE3)
Length = 803
Score = 159 bits (403), Expect = 7e-39
Identities = 82/255 (32%), Positives = 135/255 (52%), Gaps = 6/255 (2%)
Frame = +2
Query: 59 LENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVN 238
LE++YH YHN +HAADV Q+ H +S + + + ++ + HDVDHPGV+
Sbjct: 446 LEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVS 505
Query: 239 QAFLEKTNNYLSEFYKAQSVLENHHYRIALSILHETR--VFHHFTSKQWGELQYRMYKLI 412
FL TN+ L+ Y SVLENHH + +L E +F + T KQ L+ ++
Sbjct: 506 NQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIV 565
Query: 413 MATDIARQNEYLDQFTNFIE----LNIGIKEAFTKENKILIMQMALKCADICNPCREWRV 580
+ATD+++ L +E + G+ ++I ++Q + CAD+ NP + ++
Sbjct: 566 LATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQL 625
Query: 581 AACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM 760
W + I EFFRQGDRER + ++P D++ + K Q GFI ++V PL+ W + +
Sbjct: 626 YRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLV 685
Query: 761 KTRLSEKMVQQLEQN 805
++ ++ LE N
Sbjct: 686 HPD-AQDILDTLEDN 699
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,765,638
Number of Sequences: 369166
Number of extensions: 1747028
Number of successful extensions: 4313
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4075
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4214
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)