Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_D08
(835 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19425|YSPK_CAEEL Hypothetical protein F13H10.3 in chrom... 115 1e-25
sp|P0AAD4|TYRP_ECOLI Tyrosine-specific transport protein (T... 45 2e-04
sp|Q99624|S38A3_HUMAN System N amino acid transporter 1 (SN... 40 0.006
sp|Q9DCP2|S38A3_MOUSE System N amino acid transporter 1 (SN... 40 0.008
sp|Q9JHZ9|S38A3_RAT System N amino acid transporter 1 (SN1)... 40 0.008
sp|P31122|SOTB_ECOLI Sugar efflux transporter 36 0.15
sp|Q7UCG7|SOTB_SHIFL Probable sugar efflux transporter 36 0.15
sp|P58529|SOTB_ECO57 Probable sugar efflux transporter 36 0.15
sp|Q8FHE6|SOTB_ECOL6 Probable sugar efflux transporter 36 0.15
sp|Q9H598|VIAAT_HUMAN Vesicular inhibitory amino acid trans... 35 0.25
>sp|Q19425|YSPK_CAEEL Hypothetical protein F13H10.3 in chromosome IV
Length = 615
Score = 115 bits (289), Expect = 1e-25
Identities = 56/111 (50%), Positives = 79/111 (71%), Gaps = 3/111 (2%)
Frame = +1
Query: 346 VTRFSIWNTMMGTSLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKS---TENLPL 516
VT FSIWNTMMGTSLL+MPWA+QQ+G LGI +M+ +A + FYTAY+V++S ++L +
Sbjct: 167 VTIFSIWNTMMGTSLLAMPWALQQAGLVLGIIIMLSMAAICFYTAYIVIESPKRLQDLSV 226
Query: 517 EPGRTAFTSDFSDACKFYLGRPGEIVSIIFSFLALLSGLAVYYVLLCNVLY 669
+P ++FSD CK GR GE +++FS L+ G+ VY+VL+ N LY
Sbjct: 227 DP----LLAEFSDVCKSLFGRIGEYCAVVFSVCVLIGGVIVYWVLMSNFLY 273
Score = 30.8 bits (68), Expect = 4.8
Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Frame = +3
Query: 183 RYRYYLRLGVP----VIPDHVLPSRFFVLLPSQTTP--PGTQSSFITM 308
RYR Y RL +PDHVLP F +LP + G Q S +T+
Sbjct: 122 RYRLYNRLDPGGEHLTMPDHVLPPNLFSILPFEELKDVSGKQGSIVTI 169
>sp|P0AAD4|TYRP_ECOLI Tyrosine-specific transport protein (Tyrosine permease)
sp|P0AAD5|TYRP_SHIFL Tyrosine-specific transport protein (Tyrosine permease)
Length = 403
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/98 (30%), Positives = 51/98 (52%)
Frame = +1
Query: 355 FSIWNTMMGTSLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKSTENLPLEPGRTA 534
F + T +G +L+MP A GF++ + L+I + L YTA L+L+ +++P + G
Sbjct: 10 FIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLWALMCYTALLLLEVYQHVPADTG--- 66
Query: 535 FTSDFSDACKFYLGRPGEIVSIIFSFLALLSGLAVYYV 648
K YLGR G+ ++ FS + L+ L Y+
Sbjct: 67 ----LGTLAKRYLGRYGQWLT-GFSMMFLMYALTAAYI 99
>sp|Q99624|S38A3_HUMAN System N amino acid transporter 1 (SN1) (N-system amino acid
transporter 1) (Solute carrier family 38 member 3)
Length = 504
Score = 40.4 bits (93), Expect = 0.006
Identities = 34/139 (24%), Positives = 67/139 (48%), Gaps = 18/139 (12%)
Frame = +1
Query: 355 FSIWNTMMGTSLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKSTENLPL----EP 522
F++ N +MG+ +L + +A+ +G L +FL+ VA L+ Y+ +L+LKS+ + + +
Sbjct: 73 FNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQL 132
Query: 523 GRTAFTSDFSDACKFYLGRPGEIVSIIFSFLALLSGLAVYYVLLCNVLYCAVN------- 681
G AF G PG++ + + L + ++ Y ++ + L +
Sbjct: 133 GYRAF------------GTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE 180
Query: 682 -----YLNG--LISLNSIT 717
Y+NG L+ L S+T
Sbjct: 181 KTSDWYMNGNYLVILVSVT 199
>sp|Q9DCP2|S38A3_MOUSE System N amino acid transporter 1 (SN1) (N-system amino acid
transporter 1) (Solute carrier family 38 member 3)
(mNAT)
Length = 505
Score = 40.0 bits (92), Expect = 0.008
Identities = 18/49 (36%), Positives = 34/49 (69%)
Frame = +1
Query: 355 FSIWNTMMGTSLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKST 501
F++ N +MG+ +L + +A+ +G L +FL+ VA L+ Y+ +L+LKS+
Sbjct: 72 FNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSS 120
>sp|Q9JHZ9|S38A3_RAT System N amino acid transporter 1 (SN1) (N-system amino acid
transporter 1) (Solute carrier family 38 member 3)
Length = 504
Score = 40.0 bits (92), Expect = 0.008
Identities = 18/49 (36%), Positives = 34/49 (69%)
Frame = +1
Query: 355 FSIWNTMMGTSLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKST 501
F++ N +MG+ +L + +A+ +G L +FL+ VA L+ Y+ +L+LKS+
Sbjct: 72 FNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSS 120
>sp|P31122|SOTB_ECOLI Sugar efflux transporter
Length = 396
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Frame = +1
Query: 385 SLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKSTENLPLEPGRTAFTSDFSDACK 564
SL S+P ++ + I+L+ +V A YTAY ++ P F+++F+ A
Sbjct: 198 SLKSLPLLFRRPAL-MSIYLLTVVVVTAHYTAYSYIE-----PFVQNIAGFSANFATALL 251
Query: 565 FYLGRPGEIVSIIF-----SFLALLSGLAVYYVLLCNVL 666
LG G I S+IF + + L A+ +L+C L
Sbjct: 252 LLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLAL 290
>sp|Q7UCG7|SOTB_SHIFL Probable sugar efflux transporter
Length = 396
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Frame = +1
Query: 385 SLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKSTENLPLEPGRTAFTSDFSDACK 564
SL S+P ++ + I+L+ +V A YTAY ++ P F+++F+ A
Sbjct: 198 SLKSLPLLFRRPAL-MSIYLLTVVVVTAHYTAYSYIE-----PFVQNIAGFSANFATALL 251
Query: 565 FYLGRPGEIVSIIF-----SFLALLSGLAVYYVLLCNVL 666
LG G I S+IF + + L A+ +L+C L
Sbjct: 252 LLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLAL 290
>sp|P58529|SOTB_ECO57 Probable sugar efflux transporter
Length = 396
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Frame = +1
Query: 385 SLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKSTENLPLEPGRTAFTSDFSDACK 564
SL S+P ++ + I+L+ +V A YTAY ++ P F+++F+ A
Sbjct: 198 SLKSLPLLFRRPAL-MSIYLLTVVVVTAHYTAYSYIE-----PFVQNIAGFSANFATALL 251
Query: 565 FYLGRPGEIVSIIF-----SFLALLSGLAVYYVLLCNVL 666
LG G I S+IF + + L A+ +L+C L
Sbjct: 252 LLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLAL 290
>sp|Q8FHE6|SOTB_ECOL6 Probable sugar efflux transporter
Length = 396
Score = 35.8 bits (81), Expect = 0.15
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Frame = +1
Query: 385 SLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVLKSTENLPLEPGRTAFTSDFSDACK 564
SL S+P ++ + I+L+ +V A YTAY ++ P F+++F+ A
Sbjct: 198 SLKSLPLLFRRPAL-MSIYLLTVVVVTAHYTAYSYIE-----PFVQNIAGFSANFATALL 251
Query: 565 FYLGRPGEIVSIIF-----SFLALLSGLAVYYVLLCNVL 666
LG G I S+IF + + L A+ +L+C L
Sbjct: 252 LLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLAL 290
>sp|Q9H598|VIAAT_HUMAN Vesicular inhibitory amino acid transporter (GABA and glycine
transporter) (Vesicular GABA transporter) (hVIAAT)
(Solute carrier family 32 member 1)
Length = 525
Score = 35.0 bits (79), Expect = 0.25
Identities = 25/109 (22%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
Frame = +1
Query: 355 FSIWNTMMGTSLLSMPWAIQQSGFALGIFLMILVAGLAFYTAYLVL----KSTENLPLEP 522
+++ N + G +L +P+AI G+ LG+FL+I A + YT +++ + E+ +
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVR 181
Query: 523 GRTAFTSDFSDACKFYLGRPGEIVSIIFSFLALLSGLAVYYVLLCNVLY 669
R ++ + + C G V + + L+ +Y V+ N++Y
Sbjct: 182 VRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMY 230
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,097,423
Number of Sequences: 369166
Number of extensions: 1737278
Number of successful extensions: 4372
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4258
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4369
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)