Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_C09
(781 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q80VL1|TDRKH_MOUSE Tudor and KH domain-containing protein 90 8e-18
sp|Q9Y2W6|TDRKH_HUMAN Tudor and KH domain-containing protein 82 1e-15
sp|Q9BXT4|TDRD1_HUMAN Tudor domain-containing protein 1 64 5e-10
sp|Q99MV1|TDRD1_MOUSE Tudor domain-containing protein 1 55 2e-07
sp|Q8NHU6|TDRD7_HUMAN Tudor domain-containing protein 7 (Tu... 49 2e-05
sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-bin... 45 2e-04
sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-bin... 45 2e-04
sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-bindi... 45 3e-04
sp|P61407|TDRD6_MOUSE Tudor domain-containing protein 6 44 5e-04
sp|P81021|VIGLN_CHICK Vigilin 43 8e-04
>sp|Q80VL1|TDRKH_MOUSE Tudor and KH domain-containing protein
Length = 560
Score = 89.7 bits (221), Expect = 8e-18
Identities = 83/322 (25%), Positives = 136/322 (42%), Gaps = 64/322 (19%)
Frame = +1
Query: 7 PIFCIETMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTN---IQREITFRGTSE 177
P+F E + V R VG+IIG+ GE IR + + +I DK + + R I GT +
Sbjct: 124 PVF--EQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQK 181
Query: 178 NIIECKREII-KMIDSLVIKEKTCNSAS---------SIR------------------VN 273
+ K I+ K+ + ++++ +SA S+R N
Sbjct: 182 EVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREEVTEPGGAGEAALWKNTN 241
Query: 274 NDIKPSTSQP--------------------ENVKTDDINNS-----------LIKFVNYP 360
+ + P+T E D NS I ++
Sbjct: 242 SSMGPATPLEVPLRKGGGDMVVVGPKEGSWEKPNDDSFQNSGAQSSPETSMFEIPSPDFS 301
Query: 361 GEIDEKVHIYVSSVVDCSKFYAHIVGDGITSLDHLIEEMTEHF-SQIPSNTNESFKVGEI 537
DE + +YVS+ + F+ I+G LD L+ EMT+H+ + +P + + VG+I
Sbjct: 302 FHADEYLEVYVSASEHPNHFWIQIIGSRSLQLDKLVSEMTQHYENSLPEDL--TVHVGDI 359
Query: 538 VAGFYEQGGLWQRVKIIG-INNELYEIIYLDYGDSAMLTGNYLRAFEKNSKFLDLPFQAV 714
VA G W R +++G + N ++ ++D+GD+ LRA S FL LPFQA+
Sbjct: 360 VAAPLSTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCALKDLRAL--RSDFLSLPFQAI 417
Query: 715 RLITHGIQPRGDIWTEDDISEF 780
I P G+ W E+ + EF
Sbjct: 418 ECSLARIAPTGEEWEEEALDEF 439
Score = 33.5 bits (75), Expect = 0.67
Identities = 18/63 (28%), Positives = 33/63 (52%)
Frame = +1
Query: 28 MPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKREII 207
M V V IIG++G NI++L++ +IDVD + +R + G + + K I
Sbjct: 57 MRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIH 116
Query: 208 KMI 216
+++
Sbjct: 117 QIL 119
>sp|Q9Y2W6|TDRKH_HUMAN Tudor and KH domain-containing protein
Length = 606
Score = 82.4 bits (202), Expect = 1e-15
Identities = 49/139 (35%), Positives = 75/139 (53%), Gaps = 2/139 (1%)
Frame = +1
Query: 370 DEKVHIYVSSVVDCSKFYAHIVGDGITSLDHLIEEMTEHF-SQIPSNTNESFKVGEIVAG 546
DE + +YVS+ + F+ IVG LD L+ EMT+H+ + +P + + VG+IVA
Sbjct: 305 DEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL--TVHVGDIVAA 362
Query: 547 FYEQGGLWQRVKIIG-INNELYEIIYLDYGDSAMLTGNYLRAFEKNSKFLDLPFQAVRLI 723
G W R +++G + N ++ ++D+GD+ LRA S FL LPFQA+
Sbjct: 363 PLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRAL--RSDFLSLPFQAIECS 420
Query: 724 THGIQPRGDIWTEDDISEF 780
I P GD W E+ + EF
Sbjct: 421 LARIAPSGDQWEEEALDEF 439
Score = 38.1 bits (87), Expect = 0.027
Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Frame = +1
Query: 22 ETMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTN---IQREITFRGTSENIIEC 192
E + V R VG+IIG+ GE IR + + +I DK + + R I GT + +
Sbjct: 127 EQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAA 186
Query: 193 KREII-KMIDSLVIKEKTCNSASSIRVNNDIKPSTSQPENVKTDDI 327
K I+ K+ + ++++ +SA + + QP +V+ +D+
Sbjct: 187 KHLILEKVSEDEELRKRIAHSA-------ETRVPRKQPISVRREDM 225
Score = 33.5 bits (75), Expect = 0.67
Identities = 18/63 (28%), Positives = 33/63 (52%)
Frame = +1
Query: 28 MPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKREII 207
M V V IIG++G NI++L++ +IDVD + +R + G + + K I
Sbjct: 57 MRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIH 116
Query: 208 KMI 216
+++
Sbjct: 117 QIL 119
>sp|Q9BXT4|TDRD1_HUMAN Tudor domain-containing protein 1
Length = 777
Score = 63.9 bits (154), Expect = 5e-10
Identities = 41/140 (29%), Positives = 72/140 (51%), Gaps = 2/140 (1%)
Frame = +1
Query: 367 IDEKVHIYVSSVVDCSKFYAHIVG-DGITSLDHLIEEMTEHFSQIPSNTNESFKVGEIVA 543
+D+ V + V + +FY H++ D + L+ L + + EH Q N ++ ++G+
Sbjct: 309 VDQTVDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGFKA-EIGQPCC 367
Query: 544 GFYEQGGLWQRVKIIGI-NNELYEIIYLDYGDSAMLTGNYLRAFEKNSKFLDLPFQAVRL 720
F+ G W R + I N ++ ++DYG+ +T + LR +S FL+LPFQ +R
Sbjct: 368 AFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMI--SSTFLNLPFQGIRC 425
Query: 721 ITHGIQPRGDIWTEDDISEF 780
IQ R W+E+ I+ F
Sbjct: 426 QLADIQSRNKHWSEEAITRF 445
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Frame = +1
Query: 454 LDHLIEEMTEHFSQIPSNTNESFKVGEIVAGFYEQGGLWQRVKIIGINNELYEII-YLDY 630
L L ++++ Q+P ++ +G+I + + W R ++ +E ++ Y+DY
Sbjct: 117 LAELQASLSKYCDQLPPRSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDY 176
Query: 631 GDSAMLTGNYLRAFEKNSKFLDLPFQAVRLITHGIQPRGDIWTEDDI 771
G+ +L+ +R K L+LP QA++ + G++P IWT + I
Sbjct: 177 GNFEILS--LMRLCPIIPKLLELPMQAIKCVLAGVKPSLGIWTPEAI 221
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 2/125 (1%)
Frame = +1
Query: 367 IDEKVHIYVSSVVDCSKFYAHIVG--DGITSLDHLIEEMTEHFSQIPSNTNESFKVGEIV 540
+D+ + V ++ + FYA G + L L E+ E+ + S ++G+
Sbjct: 535 VDKTIQANVLEIISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRIGDAC 594
Query: 541 AGFYEQGGLWQRVKIIGINNELYEIIYLDYGDSAMLTGNYLRAFEKNSKFLDLPFQAVRL 720
Y W R ++G ++ E++Y DYG+ L R S L LPFQ +R
Sbjct: 595 CAKYTSDDFWYRAVVLGTSDTDVEVLYADYGNIETLP--LCRVQPITSSHLALPFQIIRC 652
Query: 721 ITHGI 735
G+
Sbjct: 653 SLEGL 657
>sp|Q99MV1|TDRD1_MOUSE Tudor domain-containing protein 1
Length = 928
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 2/140 (1%)
Frame = +1
Query: 367 IDEKVHIYVSSVVDCSKFYAHIV-GDGITSLDHLIEEMTEHFSQIPSNTNESFKVGEIVA 543
+DE V + V + +FY H + D + LD L + + ++ +Q P N ++ ++G
Sbjct: 462 VDETVDVVVCMMYSPGEFYCHFLKDDALEKLDDLNQSLADYCAQKPPNGFKA-EIGRPCC 520
Query: 544 GFYEQGGLWQRVKIIGI-NNELYEIIYLDYGDSAMLTGNYLRAFEKNSKFLDLPFQAVRL 720
F+ G W R + I + ++ ++DYG+ +T + L+A +FL LPFQ ++
Sbjct: 521 AFFSGDGNWYRALVKEILPSGNVKVHFVDYGNVEEVTTDQLQAILP--QFLLLPFQGMQC 578
Query: 721 ITHGIQPRGDIWTEDDISEF 780
IQP WT++ + F
Sbjct: 579 WLVDIQPPNKHWTKEATTRF 598
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/107 (24%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Frame = +1
Query: 454 LDHLIEEMTEHFSQIPSNTNESFKVGEIVAGFYEQGGLWQRVKIIGINNELYEII-YLDY 630
L L E ++E+ + ++ +G++ + + W R ++ +E ++ Y+DY
Sbjct: 271 LAELQESLSEYCGHVIPRSDFYPTIGDVCCAQFSEDDQWYRASVLAYASEESVLVGYVDY 330
Query: 631 GDSAMLTGNYLRAFEKNSKFLDLPFQAVRLITHGIQPRGDIWTEDDI 771
G+ +L+ R K LDLP QA+ + G++P IWT + +
Sbjct: 331 GNFEILS--LKRLCPIIPKLLDLPMQALNCVLAGVKPSLGIWTPEAV 375
Score = 37.0 bits (84), Expect = 0.061
Identities = 39/200 (19%), Positives = 82/200 (41%), Gaps = 6/200 (3%)
Frame = +1
Query: 151 EITFRGTSENIIECKREIIKMIDSLVIKEKTCNSASSIRVNNDIKPSTSQPENVKTDDIN 330
EIT G + + K+I ++I+E+ S + + +P+ +Q + + + +
Sbjct: 613 EITANGVGVELTDLSTPYPKIISDVLIREQLVLRCGSPQDSLMSRPA-NQHKQIDSHRVQ 671
Query: 331 NSLI----KFVNYPGEIDEKVHIYVSSVVDCSKFYA--HIVGDGITSLDHLIEEMTEHFS 492
S K + P +++ + V ++ + FYA + + L L E+ EH +
Sbjct: 672 ASPSTEQWKTMELP--VNKTIAANVLEIISPALFYAIPSEMSENQEKLCVLAAELLEHCN 729
Query: 493 QIPSNTNESFKVGEIVAGFYEQGGLWQRVKIIGINNELYEIIYLDYGDSAMLTGNYLRAF 672
+ G+ Y W R ++ + +++Y DYG+ L + ++
Sbjct: 730 AQKGQPAYRPRTGDACCAKYTNDDFWYRAIVLETSESDVKVLYADYGNIETLPLSRVQPI 789
Query: 673 EKNSKFLDLPFQAVRLITHG 732
+ L+LPFQ +R G
Sbjct: 790 P--ASHLELPFQIIRCSLEG 807
Score = 35.4 bits (80), Expect = 0.18
Identities = 26/121 (21%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
Frame = +1
Query: 412 SKFYAHIVGDGIT-SLDHLIEEMTEHFSQIPSNTNESFKVGEIVAGFYEQGGLWQR--VK 582
S FY + + +++ L + E ++ + GE+ Y W R V+
Sbjct: 27 SNFYIQLYSSEVLENMNQLSTSLKETYANVVPEDGYLPVKGEVCVAKYTVDQTWNRAIVQ 86
Query: 583 IIGINNELYEIIYLDYGDSAMLTGNYLRAFEKNSKFLDL-PFQAVRLITHGIQPRGDIWT 759
+ + ++Y+DYG+ M+ + + S+ LDL P A++ G+ P W+
Sbjct: 87 AVDVLQRKAHVLYIDYGNEEMIP---IDSVHPLSRGLDLFPPSAIKCCVSGVIPTAGEWS 143
Query: 760 E 762
E
Sbjct: 144 E 144
>sp|Q8NHU6|TDRD7_HUMAN Tudor domain-containing protein 7 (Tudor repeat associator with
PCTAIRE 2) (Trap)
Length = 1098
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/159 (25%), Positives = 76/159 (47%), Gaps = 2/159 (1%)
Frame = +1
Query: 280 IKPSTSQPENVKTDDINNSLIKFVNYPGEIDEKVHIYVSSVVDCSKFYAHIVGDGITSLD 459
++ S ++ N +DI L+ P E V V + + ++ VG ++
Sbjct: 437 VEESIAESANTFMEDITVPLLMI---PTEASPSV--LVVELSNTNEVVIRYVGKDYSAAQ 491
Query: 460 HLIE-EMTEHFSQIPSNTN-ESFKVGEIVAGFYEQGGLWQRVKIIGINNELYEIIYLDYG 633
L+E EM E++S+ P T ++ VG+++A E+ W R ++I ++ Y+DYG
Sbjct: 492 ELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDA-WLRAQVISTEENKIKVCYVDYG 550
Query: 634 DSAMLTGNYLRAFEKNSKFLDLPFQAVRLITHGIQPRGD 750
S + + +A++ N KF L FQA + G++ D
Sbjct: 551 FSENVEKS--KAYKLNPKFCSLSFQATKCKLAGLEVLSD 587
>sp|Q8VDJ3|VIGLN_MOUSE Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 25/185 (13%)
Frame = +1
Query: 34 VDNRFVGKIIGKKGENIRRLKETYKIQIDV--DKNNTNIQREITFRGTSENIIECKREII 207
+D++F +IGK G NI R+K+ YK+ + + D +N+ I G + + + KRE++
Sbjct: 442 IDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL---IRIEGDPQGVQQAKRELL 498
Query: 208 KMID--------SLVIKEK-----TCNSASSIRVNNDIKPST--SQPENVKTDDI----- 327
++ L+I+++ IR D P + P+ + DI
Sbjct: 499 ELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRG 558
Query: 328 -NNSLIKFVNYPGEI--DEKVHIYVSSVVDCSKFYAHIVGDGITSLDHLIEEMTEHFSQI 498
N + K Y ++ D + Y SV +F+ +I+G G ++ + EE
Sbjct: 559 PKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLP 618
Query: 499 PSNTN 513
N+N
Sbjct: 619 AENSN 623
Score = 38.5 bits (88), Expect = 0.021
Identities = 18/64 (28%), Positives = 35/64 (54%)
Frame = +1
Query: 22 ETMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKRE 201
E +P+D+R +IIG +G+ IR++ + +K+ I ++ +T G EN+ E
Sbjct: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDH 1189
Query: 202 IIKM 213
I+ +
Sbjct: 1190 ILNL 1193
Score = 35.4 bits (80), Expect = 0.18
Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 2/114 (1%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIR--RLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKR 198
T+P+ +IGK GE ++ LK KIQI + +N +I GT E I + +
Sbjct: 154 TVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSN---QIKITGTKEGIEKARH 210
Query: 199 EIIKMIDSLVIKEKTCNSASSIRVNNDIKPSTSQPENVKTDDINNSLIKFVNYP 360
E++ L+ E+ + + V P + P N +I +N P
Sbjct: 211 EVL-----LISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIP 259
Score = 33.9 bits (76), Expect = 0.51
Identities = 18/63 (28%), Positives = 32/63 (50%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKREI 204
++P+ +F IIGK G NI++++E +ID+ N+N I G N + I
Sbjct: 585 SVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSN-SETIIITGKRANCEAARSRI 643
Query: 205 IKM 213
+ +
Sbjct: 644 LSI 646
Score = 33.9 bits (76), Expect = 0.51
Identities = 21/69 (30%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIRRLKETYKIQIDV-DKNNTN-IQREITFRGTSENIIECKR 198
++ VD ++ KIIG+KG I +++ +++ I DK++ N Q +IT G +N +
Sbjct: 1056 SVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQFPDKDDGNQPQDQITITGYEKNTEAARD 1115
Query: 199 EIIKMIDSL 225
I+K++ L
Sbjct: 1116 AILKIVGEL 1124
Score = 30.4 bits (67), Expect = 5.7
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 58 IIGKKGENIRRL-KETYKIQIDVDKNNTNIQREITFRGTSENIIECKREIIKMIDSLVIK 234
IIGKKG+N+ ++ ++ K+ I+ T + +IT G +E++ + +I M+ L+
Sbjct: 379 IIGKKGQNLAKITQQMPKVHIEF----TEGEDKITLEGPTEDVNVAQEQIEGMVKDLI-- 432
Query: 235 EKTCNSASSIRVNNDIK 285
N + +N D K
Sbjct: 433 ----NRMDYVEINIDHK 445
>sp|Q00341|VIGLN_HUMAN Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 45.4 bits (106), Expect = 2e-04
Identities = 43/185 (23%), Positives = 80/185 (43%), Gaps = 25/185 (13%)
Frame = +1
Query: 34 VDNRFVGKIIGKKGENIRRLKETYKIQIDV--DKNNTNIQREITFRGTSENIIECKREII 207
+D++F +IGK G NI R+K+ YK+ + + D +N+ I G + + + KRE++
Sbjct: 442 IDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL---IRIEGDPQGVQQAKRELL 498
Query: 208 KMID--------SLVIKEK-----TCNSASSIRVNNDIKPST--SQPENVKTDDI----- 327
++ L+I+++ IR D P + P+ + DI
Sbjct: 499 ELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRG 558
Query: 328 -NNSLIKFVNYPGEI--DEKVHIYVSSVVDCSKFYAHIVGDGITSLDHLIEEMTEHFSQI 498
N + K Y ++ D + Y SV +F+ +I+G G ++ + EE
Sbjct: 559 PKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLP 618
Query: 499 PSNTN 513
N+N
Sbjct: 619 AENSN 623
Score = 38.5 bits (88), Expect = 0.021
Identities = 18/64 (28%), Positives = 35/64 (54%)
Frame = +1
Query: 22 ETMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKRE 201
E +P+D+R +IIG +G+ IR++ + +K+ I ++ +T G EN+ E
Sbjct: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDH 1189
Query: 202 IIKM 213
I+ +
Sbjct: 1190 ILNL 1193
Score = 33.9 bits (76), Expect = 0.51
Identities = 18/63 (28%), Positives = 32/63 (50%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKREI 204
++P+ +F IIGK G NI++++E +ID+ N+N I G N + I
Sbjct: 585 SVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSN-SETIIITGKRANCEAARSRI 643
Query: 205 IKM 213
+ +
Sbjct: 644 LSI 646
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/69 (28%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIRRLKETYKIQIDV-DKNNTN-IQREITFRGTSENIIECKR 198
++ VD ++ KIIG+KG I +++ + + I DK++ N Q +IT G +N +
Sbjct: 1056 SVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARD 1115
Query: 199 EIIKMIDSL 225
I++++ L
Sbjct: 1116 AILRIVGEL 1124
Score = 30.4 bits (67), Expect = 5.7
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 58 IIGKKGENIRRL-KETYKIQIDVDKNNTNIQREITFRGTSENIIECKREIIKMIDSLVIK 234
IIGKKG+N+ ++ ++ K+ I+ T + +IT G +E++ + +I M+ L+
Sbjct: 379 IIGKKGQNLAKITQQMPKVHIEF----TEGEDKITLEGPTEDVNVAQEQIEGMVKDLI-- 432
Query: 235 EKTCNSASSIRVNNDIK 285
N + +N D K
Sbjct: 433 ----NRMDYVEINIDHK 445
>sp|Q9Z1A6|VIGLN_RAT Vigilin (High density lipoprotein-binding protein) (HDL-binding
protein)
Length = 1268
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 4/140 (2%)
Frame = +1
Query: 34 VDNRFVGKIIGKKGENIRRLKETYKIQIDV--DKNNTNIQREITFRGTSENIIECKREII 207
+D++F +IGK G NI R+K+ YK+ + + D +N+ I G + + + KRE++
Sbjct: 442 IDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL---IRIEGDPQGVQQAKRELL 498
Query: 208 KMIDSLVIKEKTCNSASSIRVNNDIKPSTSQPENVKTDDINNSLIKFVNYPGEIDEKVHI 387
++ S + E+T + R + I + D +I F + P + E V +
Sbjct: 499 ELA-SRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPD-PAQKSEIVQL 556
Query: 388 Y--VSSVVDCSKFYAHIVGD 441
+ V C+K+ +V D
Sbjct: 557 RGPKNEVEKCTKYMQKMVAD 576
Score = 38.5 bits (88), Expect = 0.021
Identities = 18/64 (28%), Positives = 35/64 (54%)
Frame = +1
Query: 22 ETMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKRE 201
E +P+D+R +IIG +G+ IR++ + +K+ I ++ +T G EN+ E
Sbjct: 1130 EDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDH 1189
Query: 202 IIKM 213
I+ +
Sbjct: 1190 ILNL 1193
Score = 35.4 bits (80), Expect = 0.18
Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 2/114 (1%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIR--RLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKR 198
T+P+ +IGK GE ++ LK KIQI + +N +I GT E I + +
Sbjct: 154 TVPIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSN---QIKITGTKEGIEKARH 210
Query: 199 EIIKMIDSLVIKEKTCNSASSIRVNNDIKPSTSQPENVKTDDINNSLIKFVNYP 360
E++ L+ E+ + + V P + P N +I +N P
Sbjct: 211 EVL-----LISAEQDKRAVKRLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIP 259
Score = 34.3 bits (77), Expect = 0.39
Identities = 18/63 (28%), Positives = 32/63 (50%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKREI 204
++P+ +F IIGK G NI++++E +ID+ N+N I G N + I
Sbjct: 585 SVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSN-SETIVITGKRANCEAARSRI 643
Query: 205 IKM 213
+ +
Sbjct: 644 LSI 646
Score = 29.6 bits (65), Expect = 9.7
Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Frame = +1
Query: 58 IIGKKGENIRRL-KETYKIQIDVDKNNTNIQREITFRGTSENIIECKREIIKMIDSLVIK 234
IIGKKG+N+ ++ + K+ I+ T + +IT G +E++ + +I M+ L+
Sbjct: 379 IIGKKGQNLAKITHQMPKVHIEF----TEGEDKITLEGPTEDVNVAQEQIEGMVKDLI-- 432
Query: 235 EKTCNSASSIRVNNDIK 285
N + +N D K
Sbjct: 433 ----NRMDYVEINIDHK 445
>sp|P61407|TDRD6_MOUSE Tudor domain-containing protein 6
Length = 2134
Score = 43.9 bits (102), Expect = 5e-04
Identities = 22/95 (23%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Frame = +1
Query: 376 KVHIYVSSVVDCSKFYAHIVGDGITSLDHLIEEMTEHFSQIPSNTNESFKVGEIVAGFYE 555
K +YVS + D S FY ++ D +++L E + + ++ +T ++ G+++ +
Sbjct: 1312 KTSVYVSHINDLSDFYIQLIEDE-AEINNLSERLNDVRTRPQYHTGPQWQSGDVICAVFP 1370
Query: 556 QGGLWQRVKIIGIN-NELYEIIYLDYGDSAMLTGN 657
+ LW R ++ N L + ++DYG+ +++ N
Sbjct: 1371 EDNLWYRALVMEQQPNGLLSVQFIDYGNMSVVHTN 1405
>sp|P81021|VIGLN_CHICK Vigilin
Length = 1270
Score = 43.1 bits (100), Expect = 8e-04
Identities = 51/235 (21%), Positives = 99/235 (42%), Gaps = 23/235 (9%)
Frame = +1
Query: 34 VDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKREIIKM 213
VD++F +IGK G NI R+K+ YK+ + + +N I G + + + K+E++++
Sbjct: 441 VDHKFHRHLIGKNGANINRIKDLYKVSVRIPPDNEK-SNLIRIEGDPQGVQQAKKELLEL 499
Query: 214 ID--------SLVIKEK-----TCNSASSIRVNNDIKPST--SQPENVKTDDI------N 330
L+I++K IR + P + P+ DI
Sbjct: 500 ASRMENERTKDLIIEQKFHRTIIGQKGERIREIREKFPEVIINFPDPAHKSDIVQLRGPK 559
Query: 331 NSLIKFVNYPGEI--DEKVHIYVSSVVDCSKFYAHIVGDGITSLDHLIEEMTEHFSQIPS 504
N + K Y ++ D + + SV +F+ +I+G G ++ + EE ++I
Sbjct: 560 NEVEKCTKYMQKMVADLVENSFSISVPIFKQFHKNIIGKGGANIKKIREESN---TKIDL 616
Query: 505 NTNESFKVGEIVAGFYEQGGLWQRVKIIGINNELYEIIYLDYGDSAMLTGNYLRA 669
E ++++ EQ R +I+ I EL I ++ + L + + A
Sbjct: 617 PGREQATQRQLLSQGREQTVKLLRHRILAIQKELANITEVEVSIPSKLHNSLIGA 671
Score = 35.8 bits (81), Expect = 0.13
Identities = 23/97 (23%), Positives = 47/97 (48%)
Frame = +1
Query: 22 ETMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKRE 201
E + +D+R +IIG +G+ IR++ + +K+ I ++ +T G EN+ E
Sbjct: 1132 EDVTLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDH 1191
Query: 202 IIKMIDSLVIKEKTCNSASSIRVNNDIKPSTSQPENV 312
I+ ++ + + N A + +KPS+ + V
Sbjct: 1192 ILN-LEEEYLADVVDNEAMQVY----MKPSSHEESKV 1223
Score = 35.4 bits (80), Expect = 0.18
Identities = 16/61 (26%), Positives = 33/61 (54%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKREI 204
++P+ +F IIGK G NI++++E +ID+ QR++ +G + + + I
Sbjct: 584 SVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPGREQATQRQLLSQGREQTVKLLRHRI 643
Query: 205 I 207
+
Sbjct: 644 L 644
Score = 35.4 bits (80), Expect = 0.18
Identities = 21/69 (30%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Frame = +1
Query: 25 TMPVDNRFVGKIIGKKGENIRRLKETYKIQIDV-DKNN-TNIQREITFRGTSENIIECKR 198
T+ VD ++ KIIG+KG I +++ +++ I DK++ + Q +IT G +N +
Sbjct: 1058 TVTVDPKYHPKIIGRKGAVITQIRTEHEVNIQFPDKDDESQAQDQITITGYEKNAEAARD 1117
Query: 199 EIIKMIDSL 225
I+K++ L
Sbjct: 1118 AIMKIVGEL 1126
Score = 34.7 bits (78), Expect = 0.30
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Frame = +1
Query: 58 IIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSENIIECKRE---IIKMIDSLV 228
+IGK G NIR++++ +I + Q IT GT E + E ++E +IK +D++V
Sbjct: 742 LIGKGGGNIRKVRDNTGARIIFPTSEDKDQELITIMGTEEAVKEAQKELEALIKNLDNVV 801
Score = 33.1 bits (74), Expect = 0.87
Identities = 20/80 (25%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = +1
Query: 4 VPIFCIETMPVD-NRFVGKIIGKKGENIRRLKETYKIQIDVDKNNTNIQREITFRGTSEN 180
VP+ +P D +R+ IIG+KG IR++ + +++ I V IT G + N
Sbjct: 972 VPVTIEVEVPFDLHRY---IIGQKGSGIRKMMDEFEVNIQVPAPELQSSDIITITGLAAN 1028
Query: 181 IIECKREIIKMIDSLVIKEK 240
+ K +++ + L +++
Sbjct: 1029 LDRAKAGLLERVKELQAEQE 1048
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,895,510
Number of Sequences: 369166
Number of extensions: 1647722
Number of successful extensions: 5386
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5155
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5367
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7308943600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)