Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_C08
(185 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P42765|THIM_HUMAN 3-ketoacyl-CoA thiolase, mitochondrial... 70 1e-12
sp|Q8BWT1|THIM_MOUSE 3-ketoacyl-CoA thiolase, mitochondrial... 70 1e-12
sp|P13437|THIM_RAT 3-ketoacyl-CoA thiolase, mitochondrial (... 69 3e-12
sp|P76461|ATOB_ECOLI Acetyl-CoA acetyltransferase (Acetoace... 61 7e-10
sp|P44873|ATOB_HAEIN Acetyl-CoA acetyltransferase (Acetoace... 61 9e-10
sp|P45359|THLA_CLOAB Acetyl-CoA acetyltransferase (Acetoace... 61 9e-10
sp|P45363|THIL_THIVI Acetyl-CoA acetyltransferase (Acetoace... 60 2e-09
sp|P45369|THIL_CHRVI Acetyl-CoA acetyltransferase (Acetoace... 60 2e-09
sp|P14611|THIL_RALEU Acetyl-CoA acetyltransferase (Acetoace... 60 2e-09
sp|Q9ZHI1|THIL_CHRVO Acetyl-CoA acetyltransferase (Acetoace... 59 3e-09
>sp|P42765|THIM_HUMAN 3-ketoacyl-CoA thiolase, mitochondrial (Beta-ketothiolase)
(Acetyl-CoA acyltransferase) (Mitochondrial
3-oxoacyl-CoA thiolase) (T1)
Length = 397
Score = 70.5 bits (171), Expect = 1e-12
Identities = 31/44 (70%), Positives = 38/44 (86%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIE 132
GHP+G SG+RI AHLVHEL+R K A+GSACIGGGQGIA++I+
Sbjct: 351 GHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394
>sp|Q8BWT1|THIM_MOUSE 3-ketoacyl-CoA thiolase, mitochondrial (Beta-ketothiolase)
(Acetyl-CoA acyltransferase) (Mitochondrial
3-oxoacyl-CoA thiolase)
Length = 397
Score = 70.1 bits (170), Expect = 1e-12
Identities = 31/44 (70%), Positives = 38/44 (86%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIE 132
GHP+G SG+RI AHLVHEL+R K A+GSACIGGGQGIA++I+
Sbjct: 351 GHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIALIIQ 394
>sp|P13437|THIM_RAT 3-ketoacyl-CoA thiolase, mitochondrial (Beta-ketothiolase)
(Acetyl-CoA acyltransferase) (Mitochondrial
3-oxoacyl-CoA thiolase)
Length = 397
Score = 68.9 bits (167), Expect = 3e-12
Identities = 30/44 (68%), Positives = 38/44 (86%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIE 132
GHP+G SG+RI AHLVHEL+R K A+GSACIGGGQGI+++I+
Sbjct: 351 GHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGISLIIQ 394
>sp|P76461|ATOB_ECOLI Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)
Length = 394
Score = 61.2 bits (147), Expect = 7e-10
Identities = 27/46 (58%), Positives = 35/46 (76%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIERV 138
GHP+GASGARI+ L+H +Q L L + CIGGGQGIA++IER+
Sbjct: 348 GHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERL 393
>sp|P44873|ATOB_HAEIN Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)
Length = 393
Score = 60.8 bits (146), Expect = 9e-10
Identities = 26/46 (56%), Positives = 35/46 (76%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIERV 138
GHP+GASGARI+ L+H L KL L + CIGGGQGI++++ER+
Sbjct: 348 GHPIGASGARILVTLLHNLIEKDKKLGLATLCIGGGQGISMIVERL 393
>sp|P45359|THLA_CLOAB Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)
Length = 392
Score = 60.8 bits (146), Expect = 9e-10
Identities = 27/45 (60%), Positives = 34/45 (75%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIER 135
GHP+GASGARI+ LVH +Q+ K L + CIGGGQG AIL+E+
Sbjct: 347 GHPIGASGARILVTLVHAMQKRDAKKGLATLCIGGGQGTAILLEK 391
>sp|P45363|THIL_THIVI Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)
Length = 394
Score = 60.1 bits (144), Expect = 2e-09
Identities = 24/46 (52%), Positives = 36/46 (78%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIERV 138
GHP+GASGAR++ L++E+Q+ K L + CIGGGQG+A+ +ER+
Sbjct: 349 GHPIGASGARVLVTLLYEMQKRDAKKGLATLCIGGGQGVALAVERL 394
>sp|P45369|THIL_CHRVI Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)
Length = 394
Score = 60.1 bits (144), Expect = 2e-09
Identities = 24/46 (52%), Positives = 36/46 (78%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIERV 138
GHP+GASGAR++ L++E+Q+ K L + CIGGGQG+A+ +ER+
Sbjct: 349 GHPIGASGARVLVTLLYEMQKRDAKKGLATLCIGGGQGVALAVERM 394
>sp|P14611|THIL_RALEU Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)
Length = 393
Score = 59.7 bits (143), Expect = 2e-09
Identities = 25/45 (55%), Positives = 33/45 (73%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIER 135
GHP+GASG RI+ L+HE++R K L S CIGGG G+A+ +ER
Sbjct: 348 GHPIGASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVALAVER 392
>sp|Q9ZHI1|THIL_CHRVO Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)
Length = 392
Score = 59.3 bits (142), Expect = 3e-09
Identities = 24/45 (53%), Positives = 33/45 (73%)
Frame = +1
Query: 1 GHPVGASGARIMAHLVHELQRTKNKLALGSACIGGGQGIAILIER 135
GHP+GASG R++ L+HE+QR K L + CIGGG G+A+ +ER
Sbjct: 347 GHPIGASGCRVLVTLLHEMQRRGAKKGLATLCIGGGMGVALAVER 391
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,888,404
Number of Sequences: 369166
Number of extensions: 365037
Number of successful extensions: 976
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 941
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 960
length of database: 68,354,980
effective HSP length: 34
effective length of database: 62,073,990
effective search space used: 1675997730
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)