Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_010_C02 (378 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P39745|SUR1_CAEEL Mitogen-activated protein kinase mpk-1... 40 0.002 sp|P21708|MK03_RAT Mitogen-activated protein kinase 3 (Extr... 37 0.014 sp|Q63844|MK03_MOUSE Mitogen-activated protein kinase 3 (Ex... 37 0.014 sp|P28482|MK01_HUMAN Mitogen-activated protein kinase 1 (Ex... 37 0.014 sp|P63086|MK01_RAT Mitogen-activated protein kinase 1 (Extr... 37 0.014 sp|P46196|MK01_BOVIN Mitogen-activated protein kinase 1 (Ex... 37 0.014 sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 (Ex... 36 0.031 sp|P26696|MK01_XENLA Mitogen-activated protein kinase 1 (My... 36 0.031
>sp|P39745|SUR1_CAEEL Mitogen-activated protein kinase mpk-1 (MAP kinase sur-1) Length = 444 Score = 40.0 bits (92), Expect = 0.002 Identities = 18/32 (56%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVK-YFRQLE 101 PFT E E DDLP EKL+E+IWE + + R++E Sbjct: 399 PFTLEMEFDDLPKEKLKELIWEEAEAHHRRME 430
>sp|P21708|MK03_RAT Mitogen-activated protein kinase 3 (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 37.0 bits (84), Expect = 0.014 Identities = 15/28 (53%), Positives = 22/28 (78%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVKYFR 92 PFTF+ ELDDLP E+L+E+I++ F+ Sbjct: 346 PFTFDMELDDLPKERLKELIFQETARFQ 373
>sp|Q63844|MK03_MOUSE Mitogen-activated protein kinase 3 (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) (MNK1) Length = 380 Score = 37.0 bits (84), Expect = 0.014 Identities = 15/28 (53%), Positives = 22/28 (78%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVKYFR 92 PFTF+ ELDDLP E+L+E+I++ F+ Sbjct: 346 PFTFDMELDDLPKERLKELIFQETARFQ 373
>sp|P28482|MK01_HUMAN Mitogen-activated protein kinase 1 (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 360 Score = 37.0 bits (84), Expect = 0.014 Identities = 16/28 (57%), Positives = 21/28 (75%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVKYFR 92 PF F+ ELDDLP EKL+E+I+E F+ Sbjct: 328 PFKFDMELDDLPKEKLKELIFEETARFQ 355
>sp|P63086|MK01_RAT Mitogen-activated protein kinase 1 (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) sp|P63085|MK01_MOUSE Mitogen-activated protein kinase 1 (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 358 Score = 37.0 bits (84), Expect = 0.014 Identities = 16/28 (57%), Positives = 21/28 (75%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVKYFR 92 PF F+ ELDDLP EKL+E+I+E F+ Sbjct: 326 PFKFDMELDDLPKEKLKELIFEETARFQ 353
>sp|P46196|MK01_BOVIN Mitogen-activated protein kinase 1 (Extracellular signal-regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) Length = 360 Score = 37.0 bits (84), Expect = 0.014 Identities = 16/28 (57%), Positives = 21/28 (75%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVKYFR 92 PF F+ ELDDLP EKL+E+I+E F+ Sbjct: 328 PFKFDMELDDLPKEKLKELIFEETARFQ 355
>sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule-associated protein 2 kinase) Length = 379 Score = 35.8 bits (81), Expect = 0.031 Identities = 15/28 (53%), Positives = 21/28 (75%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVKYFR 92 PFTF ELDDLP E+L+E+I++ F+ Sbjct: 345 PFTFAMELDDLPKERLKELIFQETARFQ 372
>sp|P26696|MK01_XENLA Mitogen-activated protein kinase 1 (Myelin xP42 protein kinase) (Myelin basic protein kinase) (MBP kinase) (M phase MAP kinase) Length = 361 Score = 35.8 bits (81), Expect = 0.031 Identities = 16/28 (57%), Positives = 20/28 (71%) Frame = +3 Query: 9 PFTFEHELDDLPIEKLREMIWERVKYFR 92 PF FE ELDDLP E L+E+I+E F+ Sbjct: 331 PFKFEMELDDLPKETLKELIFEETARFQ 358
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,965,555 Number of Sequences: 369166 Number of extensions: 469128 Number of successful extensions: 1255 Number of sequences better than 10.0: 8 Number of HSP's better than 10.0 without gapping: 1247 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1255 length of database: 68,354,980 effective HSP length: 92 effective length of database: 51,359,360 effective search space used: 1694858880 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)