Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_B02
(795 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (Epsin... 117 5e-26
sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (Epsin... 117 5e-26
sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3) 92 2e-18
sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3) 91 5e-18
sp|P78813|YCTB_SCHPO Hypothetical protein C794.11c in chrom... 91 5e-18
sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1)... 90 6e-18
sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1) 90 6e-18
sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1)... 90 6e-18
sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2) 89 1e-17
sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2) 89 2e-17
>sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin
interacting protein localized in the trans-Golgi region)
(Clint)
Length = 625
Score = 117 bits (292), Expect = 5e-26
Identities = 66/189 (34%), Positives = 104/189 (55%), Gaps = 6/189 (3%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ ATNDD WGPSG +M EI+ TF F ++M LW R+ + N RR YK L+LL+Y
Sbjct: 29 REATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVYKSLLLLAY 88
Query: 193 LIINGSDLVAVSCKAHLHEIMKLKSY--IDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
LI NGS+ V S + H++++ L++Y +D H ++IR+K K++ + D RL +E
Sbjct: 89 LIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKELVEFAQDDDRLREE 148
Query: 364 RKRAKQYQTKHRSESAPGVTTFESKPSGNSQSLGDID-DWEPSSRSIPF--VIGESFINF 534
RK+AK+ + K+ S+ V F + + D +W+ + + PF +GE
Sbjct: 149 RKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKI 208
Query: 535 VNTFTQNIS 561
+T IS
Sbjct: 209 GSTIDDTIS 217
>sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin)
Length = 631
Score = 117 bits (292), Expect = 5e-26
Identities = 66/189 (34%), Positives = 104/189 (55%), Gaps = 6/189 (3%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ ATNDD WGPSG +M EI+ TF F ++M LW R+ + N RR YK L+LL+Y
Sbjct: 37 REATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVYKSLLLLAY 96
Query: 193 LIINGSDLVAVSCKAHLHEIMKLKSY--IDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
LI NGS+ V S + H++++ L++Y +D H ++IR+K K++ + D RL +E
Sbjct: 97 LIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKELVEFAQDDDRLREE 156
Query: 364 RKRAKQYQTKHRSESAPGVTTFESKPSGNSQSLGDID-DWEPSSRSIPF--VIGESFINF 534
RK+AK+ + K+ S+ V F + + D +W+ + + PF +GE
Sbjct: 157 RKKAKKNKDKYVGVSSDSVGGFRYNERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKI 216
Query: 535 VNTFTQNIS 561
+T IS
Sbjct: 217 GSTIDDTIS 225
>sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3)
Length = 632
Score = 91.7 bits (226), Expect = 2e-18
Identities = 56/132 (42%), Positives = 75/132 (56%), Gaps = 3/132 (2%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ AT++D WGP S+M EI+D TF+T F +VM LW R+ + N R YK L LL Y
Sbjct: 25 REATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRL-NDSGKNWRHVYKALTLLDY 83
Query: 193 LIINGSDLVAVSCKAHLHEIMKLK--SYIDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
L+ GS+ VA C+ +L+ I LK YID V++R K K + LL D +RL E
Sbjct: 84 LLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQE 143
Query: 364 RKRAKQYQTKHR 399
R A +TK R
Sbjct: 144 RTHA--LKTKER 153
>sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3)
Length = 636
Score = 90.5 bits (223), Expect = 5e-18
Identities = 55/132 (41%), Positives = 75/132 (56%), Gaps = 3/132 (2%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ AT++D WGP S+M EI+D TF+T F +VM +W R+ + N R YK L LL Y
Sbjct: 25 REATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRL-NDSGKNWRHVYKALTLLDY 83
Query: 193 LIINGSDLVAVSCKAHLHEIMKLK--SYIDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
L+ GS+ VA C+ +L+ I LK YID V++R K K + LL D +RL E
Sbjct: 84 LLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQE 143
Query: 364 RKRAKQYQTKHR 399
R A +TK R
Sbjct: 144 RTHA--LKTKER 153
>sp|P78813|YCTB_SCHPO Hypothetical protein C794.11c in chromosome III
Length = 476
Score = 90.5 bits (223), Expect = 5e-18
Identities = 64/198 (32%), Positives = 104/198 (52%), Gaps = 5/198 (2%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNN-RRTYKGLVLLS 189
+ ATN++ WG S S+M EI+ T + S ++++ + YR FTEK R+ YK L LL
Sbjct: 38 REATNNEPWGASTSLMMEIAQGTHNYSQLNEILPMI-YRRFTEKTAEEWRQIYKALQLLE 96
Query: 190 YLIINGSDLVAVSCKAHLHEIMKLKS--YIDSHNVPD--VSIRRKAKDICDLLSDSQRLC 357
+L+ NGS+ V +AH I L++ YID H D +++R +AK++ +LL+DS+R+
Sbjct: 97 FLVKNGSERVVDDARAHQATIKMLRNFHYID-HRQKDQGLNVRTRAKELVELLNDSERIR 155
Query: 358 DERKRAKQYQTKHRSESAPGVTTFESKPSGNSQSLGDIDDWEPSSRSIPFVIGESFINFV 537
ERKRA+Q + K + G + + S G S R+ + G F ++
Sbjct: 156 KERKRARQNRGKFIGVGSDGDSRISTSSKSRFPSFGSS---RGSYRTRVYGDGGGFTDYG 212
Query: 538 NTFTQNISGPPPTETHDN 591
N + + S + DN
Sbjct: 213 NGYHDSSSMSDSRDASDN 230
>sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1) (EH domain-binding mitotic
phosphoprotein)
Length = 551
Score = 90.1 bits (222), Expect = 6e-18
Identities = 53/143 (37%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ AT++D WGPS S+M EI+D T++ F ++M+ +W R+ + N R YK + L+ Y
Sbjct: 25 REATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL-NDHGKNWRHVYKAMTLMEY 83
Query: 193 LIINGSDLVAVSCKAHLHEIMKLK--SYIDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
LI GS+ V+ CK +++ + LK Y+D V++R KAK + LL D RL +E
Sbjct: 84 LIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREE 143
Query: 364 RKRA-----KQYQTKHRSESAPG 417
R A K QT S +A G
Sbjct: 144 RAHALKTKEKLAQTATASSAAVG 166
>sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1)
Length = 575
Score = 90.1 bits (222), Expect = 6e-18
Identities = 53/143 (37%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ AT++D WGPS S+M EI+D T++ F ++M+ +W R+ + N R YK + L+ Y
Sbjct: 25 REATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL-NDHGKNWRHVYKAMTLMEY 83
Query: 193 LIINGSDLVAVSCKAHLHEIMKLK--SYIDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
LI GS+ V+ CK +++ + LK Y+D V++R KAK + LL D RL +E
Sbjct: 84 LIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREE 143
Query: 364 RKRA-----KQYQTKHRSESAPG 417
R A K QT S +A G
Sbjct: 144 RAHALKTKEKLAQTATASSAAVG 166
>sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1) (Intersectin-EH binding
protein 1) (Ibp1)
Length = 566
Score = 90.1 bits (222), Expect = 6e-18
Identities = 53/143 (37%), Positives = 80/143 (55%), Gaps = 8/143 (5%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ AT++D WGPS S+M EI+D T++ F ++M+ +W R+ + N R YK + L+ Y
Sbjct: 16 REATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRL-NDHGKNWRHVYKAMTLMEY 74
Query: 193 LIINGSDLVAVSCKAHLHEIMKLK--SYIDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
LI GS+ V+ CK +++ + LK Y+D V++R KAK + LL D RL +E
Sbjct: 75 LIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREE 134
Query: 364 RKRA-----KQYQTKHRSESAPG 417
R A K QT S +A G
Sbjct: 135 RAHALKTKEKLAQTATASSAAVG 157
>sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2)
Length = 583
Score = 89.0 bits (219), Expect = 1e-17
Identities = 55/140 (39%), Positives = 82/140 (58%), Gaps = 4/140 (2%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ AT++D WGPS S+M EI+D T++ F ++M+ +W R+ + N R YK L LL Y
Sbjct: 25 REATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVWKRL-NDHGKNWRHVYKALTLLDY 83
Query: 193 LIINGSDLVAVSCKAHLHEIMKLK--SYIDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
LI GS+ VA C+ ++ I LK YID +++R K+K + LL D +RL E
Sbjct: 84 LIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVE 143
Query: 364 RKRAKQYQTKHR-SESAPGV 420
R +A +TK R ++ A GV
Sbjct: 144 RVQA--LKTKERMAQVATGV 161
>sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2)
Length = 642
Score = 88.6 bits (218), Expect = 2e-17
Identities = 51/132 (38%), Positives = 78/132 (59%), Gaps = 3/132 (2%)
Frame = +1
Query: 13 KTATNDDNWGPSGSVMKEISDETFSTSNFHDVMTFLWYRIFTEKPPNNRRTYKGLVLLSY 192
+ AT++D WGPS S+M EI+D T++ F ++M+ +W R+ + N R YK L LL Y
Sbjct: 25 REATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRL-NDHGKNWRHVYKALTLLDY 83
Query: 193 LIINGSDLVAVSCKAHLHEIMKLK--SYIDSHNVPD-VSIRRKAKDICDLLSDSQRLCDE 363
LI GS+ VA C+ ++ I LK YID +++R K+K + LL D +RL +
Sbjct: 84 LIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERL--K 141
Query: 364 RKRAKQYQTKHR 399
+RA+ +TK R
Sbjct: 142 AERAQALKTKER 153
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.314 0.132 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,415,088
Number of Sequences: 369166
Number of extensions: 1836653
Number of successful extensions: 3732
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3626
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3715
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7473924075
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)