Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_A01
(828 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P00367|DHE3_HUMAN Glutamate dehydrogenase 1, mitochondri... 347 3e-95
sp|P26443|DHE3_MOUSE Glutamate dehydrogenase 1, mitochondri... 345 1e-94
sp|P10860|DHE3_RAT Glutamate dehydrogenase 1, mitochondrial... 345 1e-94
sp|P82264|DHE3_CHAAC GLutamate dehydrogenase (GDH) 343 3e-94
sp|Q64I01|DHE4_GORGO Glutamate dehydrogenase 2, mitochondri... 342 7e-94
sp|P00366|DHE3_BOVIN Glutamate dehydrogenase 1, mitochondri... 341 1e-93
sp|P49448|DHE4_HUMAN Glutamate dehydrogenase 2, mitochondri... 339 6e-93
sp|Q64HZ9|DHE4_HYLLA Glutamate dehydrogenase 2, mitochondri... 339 6e-93
sp|Q64HZ8|DHE4_PANTR Glutamate dehydrogenase 2, mitochondri... 337 2e-92
sp|Q64I00|DHE4_PONPY Glutamate dehydrogenase 2, mitochondri... 337 2e-92
>sp|P00367|DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial precursor (GDH)
Length = 558
Score = 347 bits (889), Expect = 3e-95
Identities = 171/244 (70%), Positives = 203/244 (83%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKCI + E +GSI+N +GI P+ELED+KL+HG+I+GFP AKPY G ++
Sbjct: 314 LHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAASEKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNI+VIPDL+LNAG
Sbjct: 374 ADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I I P+ +F
Sbjct: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
RISGASE+DIVHSGL YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VYNEA
Sbjct: 494 QDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
>sp|P26443|DHE3_MOUSE Glutamate dehydrogenase 1, mitochondrial precursor (GDH)
Length = 558
Score = 345 bits (884), Expect = 1e-94
Identities = 169/244 (69%), Positives = 203/244 (83%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKC+G+ E +GSI+N +GI P+ELED+KL+HG+I+GFP AK Y G ++
Sbjct: 314 LHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAASEKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNI+VIPDL+LNAG
Sbjct: 374 ADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I + P+ +F
Sbjct: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPVVPTAEF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
RISGASE+DIVHSGL YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VYNEA
Sbjct: 494 QDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
>sp|P10860|DHE3_RAT Glutamate dehydrogenase 1, mitochondrial precursor (GDH)
(Memory-related protein 2) (MRG-2)
Length = 558
Score = 345 bits (884), Expect = 1e-94
Identities = 169/244 (69%), Positives = 203/244 (83%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKC+G+ E +GSI+N +GI P+ELED+KL+HG+I+GFP AK Y G ++
Sbjct: 314 LHSMRYLHRFGAKCVGVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKVYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAASEKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNI+VIPDL+LNAG
Sbjct: 374 ADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I + P+ +F
Sbjct: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPVVPTAEF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
RISGASE+DIVHSGL YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VYNEA
Sbjct: 494 QDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
>sp|P82264|DHE3_CHAAC GLutamate dehydrogenase (GDH)
Length = 504
Score = 343 bits (880), Expect = 3e-94
Identities = 163/244 (66%), Positives = 203/244 (83%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKC+GI E +G+I+N +GI P+ LE+YKL++GTIVGFP AKPY G ++
Sbjct: 260 LHSMRYLHRFGAKCVGIGEIDGAIYNADGIDPKALEEYKLQNGTIVGFPGAKPYEGSILE 319
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAA EKQ+T++NA +IKAKI+AEGANGPTTP+AD+I + N++VIPD++LNAG
Sbjct: 320 ADCDILIPAAGEKQLTRNNARRIKAKIIAEGANGPTTPDADKIFLENNVMVIPDMYLNAG 379
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K PI + P+ DF
Sbjct: 380 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKQGGPIPVVPTADF 439
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
R++GASE+DIVHSGL YTMERSA++IM K+NLGLD+RTAAY++ IEK+F VYNEA
Sbjct: 440 QARVAGASEKDIVHSGLAYTMERSARQIMRTASKHNLGLDIRTAAYVNAIEKVFKVYNEA 499
Query: 713 GFLF 724
G F
Sbjct: 500 GLTF 503
>sp|Q64I01|DHE4_GORGO Glutamate dehydrogenase 2, mitochondrial precursor (GDH)
Length = 558
Score = 342 bits (877), Expect = 7e-94
Identities = 169/244 (69%), Positives = 201/244 (82%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKCI + E +GSI+N +GI P+ELED++L+HG+I+GFP AKPY G ++
Sbjct: 314 LHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFRLQHGSILGFPKAKPYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAA+EKQ+TK NA ++KAKI+AEGANGPTTPEAD I Q+RNILVIPDL+LNAG
Sbjct: 374 VDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADRIFQERNILVIPDLYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I I P+ DF
Sbjct: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTADF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
ISGASE+DIVHS L YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VY+EA
Sbjct: 494 QDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVNAIEKVFKVYSEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
>sp|P00366|DHE3_BOVIN Glutamate dehydrogenase 1, mitochondrial precursor (GDH)
Length = 558
Score = 341 bits (875), Expect = 1e-93
Identities = 170/244 (69%), Positives = 201/244 (82%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKCI + E +GSI+N +GI P+ELED+KL+HGTI+GFP AK Y G ++
Sbjct: 314 LHSMRYLHRFGAKCITVGESDGSIWNPDGIDPKELEDFKLQHGTILGFPKAKIYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAASEKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNI+VIPDL+LNAG
Sbjct: 374 VDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWL N+NHVSYGRLTFKYE+DSNY LL SV +SLE K I I P+ +F
Sbjct: 434 GVTVSYFEWLNNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
RISGASE+DIVHSGL YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VYNEA
Sbjct: 494 QDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFRVYNEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
>sp|P49448|DHE4_HUMAN Glutamate dehydrogenase 2, mitochondrial precursor (GDH)
Length = 558
Score = 339 bits (869), Expect = 6e-93
Identities = 168/244 (68%), Positives = 201/244 (82%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKCI + E +GSI+N +GI P+ELED+KL+HG+I+GFP AKPY G ++
Sbjct: 314 LHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAA+EKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNILVIPDL+LNAG
Sbjct: 374 VDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDLYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I I P+ +F
Sbjct: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLSVQESLERKFGKHGGTIPIVPTAEF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
ISGASE+DIVHS L YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VY+EA
Sbjct: 494 QDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVNAIEKVFKVYSEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
>sp|Q64HZ9|DHE4_HYLLA Glutamate dehydrogenase 2, mitochondrial precursor (GDH)
Length = 555
Score = 339 bits (869), Expect = 6e-93
Identities = 167/244 (68%), Positives = 201/244 (82%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKCI + E +GSI+N +GI P+ELED+KL+HG+I+GFP AKPY G ++
Sbjct: 311 LHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILE 370
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAASEKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNI+VIPDL++NAG
Sbjct: 371 ADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYVNAG 430
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I I P+ +F
Sbjct: 431 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEF 490
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
ISGASE+DIVHS L YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VY+EA
Sbjct: 491 QDSISGASEKDIVHSALAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYSEA 550
Query: 713 GFLF 724
G F
Sbjct: 551 GVTF 554
>sp|Q64HZ8|DHE4_PANTR Glutamate dehydrogenase 2, mitochondrial precursor (GDH)
Length = 558
Score = 337 bits (865), Expect = 2e-92
Identities = 166/244 (68%), Positives = 201/244 (82%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKCI + E +GSI+N +GI P+ELED++L+HG+++GFP AKPY G ++
Sbjct: 314 LHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFRLQHGSLLGFPKAKPYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAA+EKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNILVIPDL+LNAG
Sbjct: 374 IDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDLYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I I P+ +F
Sbjct: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
ISGASE+DIVHS L YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VY+EA
Sbjct: 494 QDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVNAIEKVFKVYSEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
>sp|Q64I00|DHE4_PONPY Glutamate dehydrogenase 2, mitochondrial precursor (GDH)
Length = 558
Score = 337 bits (864), Expect = 2e-92
Identities = 165/244 (67%), Positives = 201/244 (82%), Gaps = 3/244 (1%)
Frame = +2
Query: 2 LHSMRYLVRGGAKCIGIVEYNGSIFNENGISpreLEDYKLEHGTIVGFPNAKPYTGDLMC 181
LHSMRYL R GAKC+ + E +GSI+N +GI P+ELED++L+HG+I+GFP AKPY G ++
Sbjct: 314 LHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELEDFRLQHGSILGFPKAKPYEGSILE 373
Query: 182 HECDILVPAASEKQITKDNAHKIKAKIVAEGANGPTTPEADEILQKRNILVIPDLFLNAG 361
+CDIL+PAA+EKQ+TK NA ++KAKI+AEGANGPTTPEAD+I +RNILVIPD++LNAG
Sbjct: 374 ADCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDVYLNAG 433
Query: 362 GVTVSYFEWLKNMNHVSYGRLTFKYEKDSNYMLLDSVSKSLEAKLNI---PIHITPSEDF 532
GVTVSYFEWLKN+NHVSYGRLTFKYE+DSNY LL SV +SLE K I I P+ +F
Sbjct: 434 GVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEF 493
Query: 533 ALRISGASERDIVHSGLEYTMERSAKRIMSIGKKYNLGLDLRTAAYISTIEKIFTVYNEA 712
ISGASE+DIVHS L YTMERSA++IM KYNLGLDLRTAAY++ IEK+F VY+EA
Sbjct: 494 RDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVNAIEKVFKVYSEA 553
Query: 713 GFLF 724
G F
Sbjct: 554 GVTF 557
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,375,179
Number of Sequences: 369166
Number of extensions: 1976518
Number of successful extensions: 4439
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4306
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4395
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8004331590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)