Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_P08
(649 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA... 347 1e-95
sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA... 347 1e-95
sp|Q20875|DHX15_CAEEL Putative pre-mRNA splicing factor ATP... 324 1e-88
sp|O22899|DHX15_ARATH Putative pre-mRNA splicing factor ATP... 316 4e-86
sp|P53131|PRP43_YEAST Pre-mRNA splicing factor RNA helicase... 242 7e-64
sp|O42945|DHX15_SCHPO Probable pre-mRNA splicing factor RNA... 229 6e-60
sp|O17438|DHX15_STRPU Putative pre-mRNA splicing factor ATP... 165 1e-40
sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helic... 154 2e-37
sp|O60231|DHX16_HUMAN Putative pre-mRNA splicing factor RNA... 152 7e-37
sp|Q7YR39|DHX16_PANTR Putative pre-mRNA splicing factor RNA... 152 7e-37
>sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
Length = 795
Score = 347 bits (891), Expect = 1e-95
Identities = 161/201 (80%), Positives = 183/201 (91%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHF 180
SITAMLSVPQCFVRPTEA+ AADEAKM FAHIDGDHLT+LNVYHAFKQN E QWCY++F
Sbjct: 589 SITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNF 648
Query: 181 VNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSG 360
+NYRSL +ADNVR QLSRIMDRFNL R STDF+S+DYY+NIRKALV+G+FMQVAHLER+G
Sbjct: 649 INYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTG 708
Query: 361 HYLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDM 540
HYLTVKDNQ+V LHPST LDHKPEWVLYNEFVLTTKN+IRT ++KPEWLVK+APQYYDM
Sbjct: 709 HYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDM 768
Query: 541 SNFPPCAAKEIIERIINRMQN 603
SNFP C AK ++RII ++Q+
Sbjct: 769 SNFPQCEAKRQLDRIIAKLQS 789
>sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
(ATP-dependent RNA helicase #46)
Length = 795
Score = 347 bits (891), Expect = 1e-95
Identities = 161/201 (80%), Positives = 183/201 (91%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHF 180
SITAMLSVPQCFVRPTEA+ AADEAKM FAHIDGDHLT+LNVYHAFKQN E QWCY++F
Sbjct: 589 SITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNF 648
Query: 181 VNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSG 360
+NYRSL +ADNVR QLSRIMDRFNL R STDF+S+DYY+NIRKALV+G+FMQVAHLER+G
Sbjct: 649 INYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTG 708
Query: 361 HYLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDM 540
HYLTVKDNQ+V LHPST LDHKPEWVLYNEFVLTTKN+IRT ++KPEWLVK+APQYYDM
Sbjct: 709 HYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDM 768
Query: 541 SNFPPCAAKEIIERIINRMQN 603
SNFP C AK ++RII ++Q+
Sbjct: 769 SNFPQCEAKRQLDRIIAKLQS 789
>sp|Q20875|DHX15_CAEEL Putative pre-mRNA splicing factor ATP-dependent RNA helicase F56D2.6
Length = 739
Score = 324 bits (830), Expect = 1e-88
Identities = 147/200 (73%), Positives = 175/200 (87%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHF 180
SITAMLSVPQC+VRP E RT ADEAK FAHIDGDHLT+LNVYH+FKQN+ED QWCY++F
Sbjct: 533 SITAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQEDPQWCYDNF 592
Query: 181 VNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSG 360
+NYR++K AD VR QLSR+MD++NLRR STDF S+DYY+NIRKALV+GFFMQVAHLERSG
Sbjct: 593 INYRTMKTADTVRTQLSRVMDKYNLRRVSTDFKSRDYYLNIRKALVAGFFMQVAHLERSG 652
Query: 361 HYLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDM 540
HY+TVKDNQ+V+LHPST LDHKPEW LYNEFVLTTKNFIRTV +V+PEWL+++APQYYD+
Sbjct: 653 HYVTVKDNQLVNLHPSTVLDHKPEWALYNEFVLTTKNFIRTVTDVRPEWLLQIAPQYYDL 712
Query: 541 SNFPPCAAKEIIERIINRMQ 600
NFP K + ++ +Q
Sbjct: 713 DNFPDGDTKRKLTTVMQTLQ 732
>sp|O22899|DHX15_ARATH Putative pre-mRNA splicing factor ATP-dependent RNA helicase
Length = 729
Score = 316 bits (809), Expect = 4e-86
Identities = 142/203 (69%), Positives = 173/203 (85%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHF 180
S++AMLSVP CFVRP EA+ AADEAK F HIDGDHLT+LNVYHA+KQN ED WC+E+F
Sbjct: 520 SVSAMLSVPNCFVRpreAQKAADEAKARFGHIDGDHLTLLNVYHAYKQNNEDPNWCFENF 579
Query: 181 VNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSG 360
VN R++K+ADNVR QL RIM RFNL+ STDF+S+DYYVNIRKA+++G+FMQVAHLER+G
Sbjct: 580 VNNRAMKSADNVRQQLVRIMSRFNLKMCSTDFNSRDYYVNIRKAMLAGYFMQVAHLERTG 639
Query: 361 HYLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDM 540
HYLTVKDNQ+VHLHPS CLDHKPEWV+YNE+VLTT+NFIRTV +++ EWLV VA YYD+
Sbjct: 640 HYLTVKDNQVVHLHPSNCLDHKPEWVIYNEYVLTTRNFIRTVTDIRGEWLVDVAQHYYDL 699
Query: 541 SNFPPCAAKEIIERIINRMQNGK 609
SNFP C AK +E++ + + K
Sbjct: 700 SNFPNCEAKRALEKLYKKREREK 722
>sp|P53131|PRP43_YEAST Pre-mRNA splicing factor RNA helicase PRP43 (Helicase JA1)
Length = 767
Score = 242 bits (617), Expect = 7e-64
Identities = 122/215 (56%), Positives = 157/215 (73%), Gaps = 12/215 (5%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDS----QWC 168
+I AMLSVP F+RPT+ + AD+AK FAH DGDH+T+LNVYHAFK + +WC
Sbjct: 544 TIVAMLSVPNVFIRPTKDKKRADDAKNIFAHPDGDHITLLNVYHAFKSDEAYEYGIHKWC 603
Query: 169 YEHFVNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHL 348
+H++NYRSL AADN+R QL R+M+R+NL ++TD+ S Y+ NIRKAL SGFFMQVA
Sbjct: 604 RDHYLNYRSLSAADNIRSQLERLMNRYNLELNTTDYESPKYFDNIRKALASGFFMQVAK- 662
Query: 349 ERSGH--YLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVA 522
+RSG Y+TVKDNQ V +HPST L H EWV+YNEFVLT+KN+IRTV V+PEWL+++A
Sbjct: 663 KRSGAKGYITVKDNQDVLIHPSTVLGHDAEWVIYNEFVLTSKNYIRTVTSVRPEWLIEIA 722
Query: 523 PQYYDMSNFPPCAAKEIIERI------INRMQNGK 609
P YYD+SNF K +ERI +N ++ GK
Sbjct: 723 PAYYDLSNFQKGDVKLSLERIKEKVDRLNELKQGK 757
>sp|O42945|DHX15_SCHPO Probable pre-mRNA splicing factor RNA helicase prp43
Length = 735
Score = 229 bits (583), Expect = 6e-60
Identities = 108/184 (58%), Positives = 138/184 (75%), Gaps = 1/184 (0%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHF 180
S+TA+LSVP FVRP AR ADE + F H DGDHLT+LNVYHA+K + WC+ HF
Sbjct: 526 SLTALLSVPNVFVRPNSARKLADEMRQQFTHPDGDHLTLLNVYHAYKSGEGTADWCWNHF 585
Query: 181 VNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSG 360
+++R+L +ADNVR QL R M+R + ST F K+YYVNIR+ALVSGFFMQVA +G
Sbjct: 586 LSHRALISADNVRKQLRRTMERQEVELISTPFDDKNYYVNIRRALVSGFFMQVAKKSANG 645
Query: 361 -HYLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYD 537
+Y+T+KDNQ+V LHPS L PEWV+YNEFVLTTK+FIR V ++PEWL+++AP YYD
Sbjct: 646 KNYVTMKDNQVVSLHPSCGLSVTPEWVVYNEFVLTTKSFIRNVTAIRPEWLIELAPNYYD 705
Query: 538 MSNF 549
+ +F
Sbjct: 706 LDDF 709
>sp|O17438|DHX15_STRPU Putative pre-mRNA splicing factor ATP-dependent RNA helicase PRP1
Length = 455
Score = 165 bits (417), Expect = 1e-40
Identities = 75/99 (75%), Positives = 90/99 (90%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHF 180
S+TAMLSVPQCF+RP EA+ ADEAKM FAHIDGDHLT+LNVYHAFKQN ED QWCY++F
Sbjct: 357 SVTAMLSVPQCFLRPNEAKKLADEAKMRFAHIDGDHLTLLNVYHAFKQNNEDPQWCYDNF 416
Query: 181 VNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYV 297
+ YRSLK+AD+VR QL+RIMDRF L+R+ST+F+SKDYY+
Sbjct: 417 IQYRSLKSADSVRQQLARIMDRFALQRTSTNFNSKDYYL 455
>sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helicase HRH1) (DEAH-box protein 8)
Length = 1220
Score = 154 bits (388), Expect = 2e-37
Identities = 77/183 (42%), Positives = 117/183 (63%), Gaps = 1/183 (0%)
Frame = +1
Query: 1 SITAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHF 180
+I +MLSV F RP + + AD+ K F +GDHLT+L VY+++K N+ + WCYE+F
Sbjct: 1007 TIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENF 1066
Query: 181 VNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSG 360
+ RSL+ A ++R Q+ IMDR L S S+ V ++KA+ SGFF A +
Sbjct: 1067 IQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKST----VRVQKAICSGFFRNAAKKDPQE 1122
Query: 361 HYLTVKDNQIVHLHPSTCL-DHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYD 537
Y T+ D Q+V++HPS+ L + +PEWV+Y+E VLTTK ++R V + P WLV+ AP ++
Sbjct: 1123 GYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFK 1182
Query: 538 MSN 546
+S+
Sbjct: 1183 VSD 1185
>sp|O60231|DHX16_HUMAN Putative pre-mRNA splicing factor RNA helicase (ATP-dependent RNA
helicase #3) (DEAH-box protein 16)
Length = 1041
Score = 152 bits (384), Expect = 7e-37
Identities = 82/197 (41%), Positives = 121/197 (61%), Gaps = 2/197 (1%)
Frame = +1
Query: 1 SITAMLSVPQC-FVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEH 177
++ AMLSV F RP + AD A++ F GDHL +LNVY + ++ SQWCYE+
Sbjct: 842 TVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYEN 901
Query: 178 FVNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERS 357
FV +RS++ A +VR QL +++R + SS Y+ +RKA+ +G+F A L RS
Sbjct: 902 FVQFRSMRRARDVREQLEGLLERVEVGLSSCQGD----YIRVRKAITAGYFYHTARLTRS 957
Query: 358 GHYLTVKDNQIVHLHPSTCL-DHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYY 534
G Y TVK Q V +HP++ L + +P W+LY+E VLTTK F+R V E++ WL++VAP YY
Sbjct: 958 G-YRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYY 1016
Query: 535 DMSNFPPCAAKEIIERI 585
AK++ ++I
Sbjct: 1017 KAKELEDPHAKKMPKKI 1033
>sp|Q7YR39|DHX16_PANTR Putative pre-mRNA splicing factor RNA helicase (ATP-dependent RNA
helicase #3) (DEAH-box protein 16)
Length = 1044
Score = 152 bits (384), Expect = 7e-37
Identities = 82/197 (41%), Positives = 121/197 (61%), Gaps = 2/197 (1%)
Frame = +1
Query: 1 SITAMLSVPQC-FVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEH 177
++ AMLSV F RP + AD A++ F GDHL +LNVY + ++ SQWCYE+
Sbjct: 845 TVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYEN 904
Query: 178 FVNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERS 357
FV +RS++ A +VR QL +++R + SS Y+ +RKA+ +G+F A L RS
Sbjct: 905 FVQFRSMRRARDVREQLEGLLERVEVGLSSCQGD----YIRVRKAITAGYFYHTARLTRS 960
Query: 358 GHYLTVKDNQIVHLHPSTCL-DHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYY 534
G Y TVK Q V +HP++ L + +P W+LY+E VLTTK F+R V E++ WL++VAP YY
Sbjct: 961 G-YRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYY 1019
Query: 535 DMSNFPPCAAKEIIERI 585
AK++ ++I
Sbjct: 1020 KAKELEDPHAKKMPKKI 1036
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,420,319
Number of Sequences: 369166
Number of extensions: 1796383
Number of successful extensions: 5103
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4940
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5057
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5316264630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)