Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_P05
(814 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9GZT4|SRR_HUMAN Serine racemase 118 2e-26
sp|Q9QZX7|SRR_MOUSE Serine racemase 115 2e-25
sp|P36007|YKV8_YEAST Hypothetical 34.9 kDa protein in COS9-... 112 2e-24
sp|O59791|YCNE_SCHPO Hypothetical protein C320.14 in chromo... 103 7e-22
sp|O42615|THDH_ARXAD Threonine dehydratase, mitochondrial p... 96 2e-19
sp|P00927|THDH_YEAST Threonine dehydratase, mitochondrial p... 88 2e-17
sp|P46493|THD1_HAEIN Threonine dehydratase biosynthetic (Th... 87 4e-17
sp|P25306|THD1_LYCES Threonine dehydratase biosynthetic, ch... 87 7e-17
sp|Q9ZSS6|THD1_ARATH Threonine dehydratase biosynthetic, ch... 82 2e-15
sp|P20506|THD1_SALTY Threonine dehydratase biosynthetic (Th... 81 4e-15
>sp|Q9GZT4|SRR_HUMAN Serine racemase
Length = 340
Score = 118 bits (295), Expect = 2e-26
Identities = 74/208 (35%), Positives = 111/208 (53%)
Frame = +2
Query: 50 VVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAKIVFSEDTPQSREEL 229
VVTHSSGNHGQA YAAKL IPA IVVP++ P K AI YGA IV+ E + +SRE +
Sbjct: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENV 138
Query: 230 CSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPNLDAVLISISXXXXXXXXXXXXK 409
++ +E GQGT+ +E L Q+P +DA+++ + K
Sbjct: 139 AKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVK 198
Query: 410 NLNPKIRVYCVEPFGKELEESLRSGSRLWKGEQKCLDTVAEGLKVHHPGQLTFPILCDLA 589
L P ++VY EP + + +L +T+A+G+K G T+PI+ DL
Sbjct: 199 ALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYP-PETIADGVK-SSIGLNTWPIIRDLV 256
Query: 590 ERNIFSVTNSEMIEGVKMSMKYLKQVIE 673
+ +IF+VT E+ ++ + +K +IE
Sbjct: 257 D-DIFTVTEDEIKCATQLVWERMKLLIE 283
>sp|Q9QZX7|SRR_MOUSE Serine racemase
Length = 339
Score = 115 bits (287), Expect = 2e-25
Identities = 75/212 (35%), Positives = 114/212 (53%), Gaps = 4/212 (1%)
Frame = +2
Query: 50 VVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAKIVFSEDTPQSREEL 229
VVTHSSGNHGQA YAAKL IPA IVVP++ P K AI YGA IV+ + + +SRE++
Sbjct: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYCDPSDESREKV 138
Query: 230 CSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPNLDAVLISISXXXXXXXXXXXXK 409
++ +E GQGT+ +E L Q+P +DA+++ + K
Sbjct: 139 TQRIMQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIK 198
Query: 410 NLNPKIRVYCVEPFGKELEESLRSGSRLWKGE----QKCLDTVAEGLKVHHPGQLTFPIL 577
L P ++VY EP ++ +S KGE +T+A+G+K G T+PI+
Sbjct: 199 ALKPSVKVYAAEP--SNADDCYQS---KLKGELTPNLHPPETIADGVK-SSIGLNTWPII 252
Query: 578 CDLAERNIFSVTNSEMIEGVKMSMKYLKQVIE 673
DL + ++F+VT E+ ++ +K +IE
Sbjct: 253 RDLVD-DVFTVTEDEIKYATQLVWGRMKLLIE 283
>sp|P36007|YKV8_YEAST Hypothetical 34.9 kDa protein in COS9-JEN1 intergenic region
Length = 326
Score = 112 bits (279), Expect = 2e-24
Identities = 69/223 (30%), Positives = 120/223 (53%), Gaps = 2/223 (0%)
Frame = +2
Query: 11 NILCKL-EKQNINGVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAK 187
N + KL +++ GV+ SSGNH QA A +AKLLN+PA IV+P+ P +K A YGA
Sbjct: 59 NAVSKLSDEKRSKGVIAFSSGNHAQAIALSAKLLNVPATIVMPEDAPALKVAATAGYGAH 118
Query: 188 IVFSEDTPQSREELCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPNLDAVLISI 367
I+ + RE++ ++A E+ GQGT E L+++ LDA+ + +
Sbjct: 119 IIRYNRYTEDREQIGRQLAAEHGFALIPPYDHPDVIAGQGTSAKELLEEVGQLDALFVPL 178
Query: 368 SXXXXXXXXXXXXKNLNPKIRVYCVEP-FGKELEESLRSGSRLWKGEQKCLDTVAEGLKV 544
++L+P +++ VEP G + ++S RSGS + K T+A+G +
Sbjct: 179 GGGGLLSGSALAARSLSPGCKIFGVEPEAGNDGQQSFRSGSIVHINTPK---TIADGAQT 235
Query: 545 HHPGQLTFPILCDLAERNIFSVTNSEMIEGVKMSMKYLKQVIE 673
H G+ TF I+ + + +I +V++ E+++ + + +K V+E
Sbjct: 236 QHLGEYTFAIIRENVD-DILTVSDQELVKCMHFLAERMKVVVE 277
>sp|O59791|YCNE_SCHPO Hypothetical protein C320.14 in chromosome III
Length = 323
Score = 103 bits (256), Expect = 7e-22
Identities = 67/223 (30%), Positives = 111/223 (49%), Gaps = 2/223 (0%)
Frame = +2
Query: 11 NILCKL-EKQNINGVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAK 187
N L +L E Q GV+T SSGNH QA A +AK+L IPA I++P P+ K A YG +
Sbjct: 63 NALSQLNEAQRKAGVLTFSSGNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQ 122
Query: 188 IVFSEDTPQSREELCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPNLDAVLISI 367
++ + RE++ ++++ GQGT E +++ LDA+ + +
Sbjct: 123 VIMYDRYKDDREKMAKEISEREGLTIIPPYDHPHVLAGQGTAAKELFEEVGPLDALFVCL 182
Query: 368 SXXXXXXXXXXXXKNLNPKIRVYCVEP-FGKELEESLRSGSRLWKGEQKCLDTVAEGLKV 544
++ P VY VEP G + ++S R GS + K T+A+G +
Sbjct: 183 GGGGLLSGSALAARHFAPNCEVYGVEPEAGNDGQQSFRKGSIVHIDTPK---TIADGAQT 239
Query: 545 HHPGQLTFPILCDLAERNIFSVTNSEMIEGVKMSMKYLKQVIE 673
H G TF I+ + + +I +V++ E+I+ +K +K V+E
Sbjct: 240 QHLGNYTFSIIKEKVD-DILTVSDEELIDCLKFYAARMKIVVE 281
>sp|O42615|THDH_ARXAD Threonine dehydratase, mitochondrial precursor (Threonine
deaminase)
Length = 550
Score = 95.5 bits (236), Expect = 2e-19
Identities = 66/230 (28%), Positives = 109/230 (47%), Gaps = 3/230 (1%)
Frame = +2
Query: 47 GVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAKIVFSEDTPQSREE 226
GV+ S+GNH Q AY+AK LNIPA IV+P TP IK + + GAK+V + + +
Sbjct: 105 GVIACSAGNHAQGVAYSAKHLNIPATIVMPVVTPAIKYKNVDRLGAKVVLHGNDFDAAKA 164
Query: 227 LCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQI--PNLDAVLISISXXXXXXXXXX 400
C+++++++ GQGT+G+E L+QI +L A+ + I
Sbjct: 165 ECNRLSEKHGLTNIPLFDNPYVIAGQGTIGVELLRQIDVESLKAIFVCIGGGGLIAGVGA 224
Query: 401 XXKNLNPKIRVYCVEPF-GKELEESLRSGSRLWKGEQKCLDTVAEGLKVHHPGQLTFPIL 577
K + P++++ VE + + +SL+ G R+ E + A+G V G+ TF L
Sbjct: 225 YIKRIAPQVKIIGVETYDANAMRQSLQKGERITLSE---VGLFADGAAVKILGEETFR-L 280
Query: 578 CDLAERNIFSVTNSEMIEGVKMSMKYLKQVIEHXXXXXXXXLFKYNKDIP 727
C I V+ E+ +K + ++E L KY + P
Sbjct: 281 CQQVVDEIVLVSTDEICAAIKDVFTETRSIVEPAGALSVAGLVKYVESHP 330
>sp|P00927|THDH_YEAST Threonine dehydratase, mitochondrial precursor (Threonine
deaminase)
Length = 576
Score = 88.2 bits (217), Expect = 2e-17
Identities = 67/240 (27%), Positives = 111/240 (46%), Gaps = 6/240 (2%)
Frame = +2
Query: 11 NILCKLEKQNIN-GVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAK 187
N++ KL+ N GV+ S+GNH Q A+AAK L IPA IV+P TP IK + ++ G++
Sbjct: 115 NMIAKLDDSQRNQGVIACSAGNHAQGVAFAAKHLKIPATIVMPVCTPSIKYQNVSRLGSQ 174
Query: 188 IV-FSEDTPQSREELCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQI---PNLDAV 355
+V + D +++ E C+K+A+E GQGT+ ME L+Q+ + AV
Sbjct: 175 VVLYGNDFDEAKAE-CAKLAEERGLTNIPPFDHPYVIAGQGTVAMEILRQVRTANKIGAV 233
Query: 356 LISISXXXXXXXXXXXXKNLNPKIRVYCVEPF-GKELEESLRSGSRLWKGEQKCLDTVAE 532
+ + K + P I++ VE + L SL+ R + T A+
Sbjct: 234 FVPVGGGGLIAGIGAYLKRVAPHIKIIGVETYDAATLHNSLQRNQRT---PLPVVGTFAD 290
Query: 533 GLKVHHPGQLTFPILCDLAERNIFSVTNSEMIEGVKMSMKYLKQVIEHXXXXXXXXLFKY 712
G V G+ TF + + + + V E+ VK + + ++E + KY
Sbjct: 291 GTSVRMIGEETFRVAQQVVD-EVVLVNTDEICAAVKDIFEDTRSIVEPSGALSVAGMKKY 349
>sp|P46493|THD1_HAEIN Threonine dehydratase biosynthetic (Threonine deaminase)
Length = 513
Score = 87.4 bits (215), Expect = 4e-17
Identities = 66/239 (27%), Positives = 108/239 (45%), Gaps = 3/239 (1%)
Frame = +2
Query: 32 KQNINGVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAKIVFSEDTP 211
+Q GV+ S+GNH Q A +AK L + A+IV+P++TP IK +A+ +G +++
Sbjct: 77 EQKAAGVIAASAGNHAQGVALSAKQLGLKALIVMPQNTPSIKVDAVRGFGGEVLLHGANF 136
Query: 212 QSREELCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPNLDAVLISISXXXXXXX 391
+ +++KE GQGTL ME L+Q+ +LD V + +
Sbjct: 137 DEAKAKAIELSKEKNMTFIPPFDHPLVIAGQGTLAMEMLQQVADLDYVFVQVGGGGLAAG 196
Query: 392 XXXXXKNLNPKIRVYCVEPFGKELEESLRSGSRLWKGEQKCLDTV---AEGLKVHHPGQL 562
K P+I++ G E ++S + L KGE L + A+G+ V G
Sbjct: 197 VAILLKQFMPEIKI-----IGVESKDSACLKAALDKGEPTDLTHIGLFADGVAVKRIGDE 251
Query: 563 TFPILCDLAERNIFSVTNSEMIEGVKMSMKYLKQVIEHXXXXXXXXLFKYNKDIPLECK 739
TF LC ++ V + E+ +K + ++ V E L KY K +E K
Sbjct: 252 TFR-LCQQYLDDMVLVDSDEVCAAMKDLFENVRAVAEPSGALGLAGLKKYVKQNHIEGK 309
>sp|P25306|THD1_LYCES Threonine dehydratase biosynthetic, chloroplast precursor
(Threonine deaminase) (TD)
Length = 595
Score = 86.7 bits (213), Expect = 7e-17
Identities = 55/188 (29%), Positives = 93/188 (49%), Gaps = 2/188 (1%)
Frame = +2
Query: 11 NILCKLEKQNIN-GVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAK 187
N++ L ++ ++ GV+T S+GNH Q A A + LN A IV+P +TPQIK +A+ G
Sbjct: 149 NMMSNLSREELDKGVITASAGNHAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGD 208
Query: 188 IVFSEDTPQSREELCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPNLDAVLISI 367
+V T + ++++++ GQGT+G E +Q+ ++ AV I +
Sbjct: 209 VVLYGKTFDEAQTHALELSEKDGLKYIPPFDDPGVIKGQGTIGTEINRQLKDIHAVFIPV 268
Query: 368 SXXXXXXXXXXXXKNLNPKIRVYCVEPFG-KELEESLRSGSRLWKGEQKCLDTVAEGLKV 544
K + P ++ VEP+G + SL G R+ + +DT A+G+ V
Sbjct: 269 GGGGLIAGVATFFKQIAPNTKIIGVEPYGAASMTLSLHEGHRV---KLSNVDTFADGVAV 325
Query: 545 HHPGQLTF 568
G+ TF
Sbjct: 326 ALVGEYTF 333
>sp|Q9ZSS6|THD1_ARATH Threonine dehydratase biosynthetic, chloroplast precursor
(Threonine deaminase) (TD)
Length = 592
Score = 81.6 bits (200), Expect = 2e-15
Identities = 61/226 (26%), Positives = 103/226 (45%), Gaps = 5/226 (2%)
Frame = +2
Query: 11 NILCKLEKQNI-NGVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAK 187
N++ KL + GV+ S+GNH Q A +A L A+IV+P +TP+IK +A+ GA
Sbjct: 147 NMMVKLPADQLAKGVICSSAGNHAQGVALSASKLGCTAVIVMPVTTPEIKWQAVENLGAT 206
Query: 188 IVFSEDTPQSREELCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPN-LDAVLIS 364
+V D+ + A+E GQGT+GME +Q L A+ +
Sbjct: 207 VVLFGDSYDQAQAHAKIRAEEEGLTFIPPFDHPDVIAGQGTVGMEITRQAKGPLHAIFVP 266
Query: 365 ISXXXXXXXXXXXXKNLNPKIRVYCVEPFGKELEESLRSGSRLWKGEQKCLDTV---AEG 535
+ K ++P++++ VEP ++ L GE+ LD V A+G
Sbjct: 267 VGGGGLIAGIAAYVKRVSPEVKIIGVEP-----ADANAMALSLHHGERVILDQVGGFADG 321
Query: 536 LKVHHPGQLTFPILCDLAERNIFSVTNSEMIEGVKMSMKYLKQVIE 673
+ V G+ TF I +L + + VT + +K + + ++E
Sbjct: 322 VAVKEVGEETFRISRNLMD-GVVLVTRDAICASIKDMFEEKRNILE 366
>sp|P20506|THD1_SALTY Threonine dehydratase biosynthetic (Threonine deaminase)
Length = 514
Score = 80.9 bits (198), Expect = 4e-15
Identities = 62/231 (26%), Positives = 104/231 (45%), Gaps = 3/231 (1%)
Frame = +2
Query: 29 EKQNINGVVTHSSGNHGQATAYAAKLLNIPAIIVVPKSTPQIKCEAITFYGAKIVFSEDT 208
E+Q +GV+T S+GNH Q A+++ L + ++IV+PK+T IK +A+ +G +++
Sbjct: 75 EEQKAHGVITASAGNHAQGVAFSSARLGVKSLIVMPKATADIKVDAVRGFGGEVLLHGAN 134
Query: 209 PQSREELCSKMAKENXXXXXXXXXXXXXXNGQGTLGMEFLKQIPNLDAVLISISXXXXXX 388
+ ++A++ GQGTL +E L+Q +LD V + +
Sbjct: 135 FDEAKAKAIELAQQQGFTWVPPFDHPMVIAGQGTLALELLQQDSHLDRVFVPVGGGGLAA 194
Query: 389 XXXXXXKNLNPKIRVYCVEPFGKELEESLRSGSRLWKGEQKCLDTV---AEGLKVHHPGQ 559
K L P+I+V V E E+S + L G L V AEG+ V G
Sbjct: 195 GVAVLIKQLMPQIKVIAV-----EAEDSACLKAALEAGHPVDLPRVGLFAEGVAVKRIGD 249
Query: 560 LTFPILCDLAERNIFSVTNSEMIEGVKMSMKYLKQVIEHXXXXXXXXLFKY 712
TF LC +I +V + + +K + ++ V E + KY
Sbjct: 250 ETFR-LCQEYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKY 299
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,727,218
Number of Sequences: 369166
Number of extensions: 1640337
Number of successful extensions: 4119
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4034
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4099
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)