Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_O23
(812 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q91W89|MA2C1_MOUSE Alpha-mannosidase 2C1 (Alpha-D-mannos... 145 2e-34
sp|Q9NTJ4|MA2C1_HUMAN Alpha-mannosidase 2C1 (Alpha-D-mannos... 145 2e-34
sp|P21139|MA2C1_RAT Alpha-mannosidase 2C1 (Alpha-D-mannosid... 130 4e-30
sp|P22855|MAN1_YEAST Alpha-mannosidase (Alpha-D-mannoside m... 118 2e-26
sp|P46081|BXCN_CLOBO Botulinum neurotoxin type C1, nontoxic... 33 0.93
sp|Q64929|VP4_AHSV4 VP4 core protein (Inner capsid protein ... 32 1.6
sp|Q62IJ6|ATKA_BURMA Potassium-transporting ATPase A chain ... 31 3.5
sp|Q63VS3|ATKA_BURPS Potassium-transporting ATPase A chain ... 31 3.5
sp|O67244|FLGB_AQUAE Flagellar basal-body rod protein flgB 31 4.6
sp|P36135|UTH1_YEAST UTH1 protein 30 7.9
>sp|Q91W89|MA2C1_MOUSE Alpha-mannosidase 2C1 (Alpha-D-mannoside mannohydrolase) (Mannosidase
alpha class 2C member 1)
Length = 1039
Score = 145 bits (365), Expect = 2e-34
Identities = 78/199 (39%), Positives = 109/199 (54%)
Frame = +3
Query: 69 NQIMIFDDVPLFWDAWDVMDYHLETGVDIECIPSFRILQEIEVVKSNRSVSLLYKSRLEN 248
NQ ++FDDVPL+WDAWDVMDYHLET P + V + +
Sbjct: 723 NQFVLFDDVPLYWDAWDVMDYHLETRK-----PVLGQAGTLAVGTEGGLRGSAWFLLQIS 777
Query: 249 TQTTIEQSITIYDNVEYCNMCTKVIEWNETHKMMKVKIPTVVNATDAQYCTQTGYLSRPT 428
+ + Q + + Y T+V W+E HK +KV+ P + + A Y Q G+L RPT
Sbjct: 778 PNSRLSQEVVLDVGCPYVRFHTEV-HWHEAHKFLKVEFPARIRSPQATYEIQFGHLQRPT 836
Query: 429 HRNTSWDSAKFEVCGHDWIHIGETNWGVTVLKEAIFGSSVVDGTVYLSLLRSPNSPDATA 608
H NTSWD A++EV H WI + E ++G+ +L +G+SV + LSLLR+P +PDATA
Sbjct: 837 HNNTSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGASVRGNVLSLSLLRAPKAPDATA 896
Query: 609 DKKHIPHVFNYAIYPYDSS 665
D H F YA+ P+ S
Sbjct: 897 DMGR--HEFTYALMPHKGS 913
>sp|Q9NTJ4|MA2C1_HUMAN Alpha-mannosidase 2C1 (Alpha-D-mannoside mannohydrolase) (Mannosidase
alpha class 2C member 1) (Alpha mannosidase 6A8B)
Length = 1040
Score = 145 bits (365), Expect = 2e-34
Identities = 79/199 (39%), Positives = 110/199 (55%)
Frame = +3
Query: 69 NQIMIFDDVPLFWDAWDVMDYHLETGVDIECIPSFRILQEIEVVKSNRSVSLLYKSRLEN 248
NQ ++FDDVPL+WDAWDVMDYHLET P + V + +
Sbjct: 724 NQFVLFDDVPLYWDAWDVMDYHLETRK-----PVLGQAGTLAVGTEGGLRGSAWFLLQIS 778
Query: 249 TQTTIEQSITIYDNVEYCNMCTKVIEWNETHKMMKVKIPTVVNATDAQYCTQTGYLSRPT 428
+ + Q + + Y T+V W+E HK +KV+ P V ++ A Y Q G+L RPT
Sbjct: 779 PNSRLSQEVVLDVGCPYVRFHTEV-HWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPT 837
Query: 429 HRNTSWDSAKFEVCGHDWIHIGETNWGVTVLKEAIFGSSVVDGTVYLSLLRSPNSPDATA 608
H NTSWD A+FEV H W+ + E +G+ +L + +G+SV + LSLLR+P +PDATA
Sbjct: 838 HYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATA 897
Query: 609 DKKHIPHVFNYAIYPYDSS 665
D H F YA+ P+ S
Sbjct: 898 DTGR--HEFTYALMPHKGS 914
>sp|P21139|MA2C1_RAT Alpha-mannosidase 2C1 (Alpha-D-mannoside mannohydrolase) (Mannosidase
alpha class 2C member 1) (AMAN)
Length = 1040
Score = 130 bits (327), Expect = 4e-30
Identities = 72/199 (36%), Positives = 106/199 (53%)
Frame = +3
Query: 69 NQIMIFDDVPLFWDAWDVMDYHLETGVDIECIPSFRILQEIEVVKSNRSVSLLYKSRLEN 248
NQ ++FDDVPL+WDAWDVMDYHLET + + ++ + L +
Sbjct: 724 NQFVLFDDVPLYWDAWDVMDYHLETRKPVRGQAGTLAVGAEGGLRGSAWFLLQI-----S 778
Query: 249 TQTTIEQSITIYDNVEYCNMCTKVIEWNETHKMMKVKIPTVVNATDAQYCTQTGYLSRPT 428
+ + Q + + Y T+V W+ETHK +KV+ P V + A Y Q G+L
Sbjct: 779 PNSRLSQEVVLDVGCPYVRFHTEV-HWHETHKFLKVEFPARVRSPQATYEIQFGHLQEAD 837
Query: 429 HRNTSWDSAKFEVCGHDWIHIGETNWGVTVLKEAIFGSSVVDGTVYLSLLRSPNSPDATA 608
+ SWD A++EV H WI + E ++G+ +L +G+SV + LSLLR+P +PD TA
Sbjct: 838 PQQHSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGTSVRGNVLSLSLLRAPKAPDVTA 897
Query: 609 DKKHIPHVFNYAIYPYDSS 665
D H F YA+ P+ S
Sbjct: 898 DMGR--HEFTYALMPHKGS 914
>sp|P22855|MAN1_YEAST Alpha-mannosidase (Alpha-D-mannoside mannohydrolase)
Length = 1083
Score = 118 bits (296), Expect = 2e-26
Identities = 75/225 (33%), Positives = 117/225 (52%), Gaps = 3/225 (1%)
Frame = +3
Query: 54 NDWPANQIMIFDDVPLFWDAWDVMDYHLETGVDIECIPSFRILQEIEVVKSNRSVSLLYK 233
N ANQ +I+DD PL W AWD Y + + + + +Q K +V ++++
Sbjct: 745 NKLGANQFVIYDDKPLGWQAWDTELYSVN---QYKYVTKPKKVQVSCNTKEKCAVEVIFQ 801
Query: 234 -SRLENTQTTIEQSITIYDNVEYC--NMCTKVIEWNETHKMMKVKIPTVVNATDAQYCTQ 404
S ++ I + T + + ++ T V W+ +K +KV+ P + A Y TQ
Sbjct: 802 ISEKCKIKSVISLNATAVTDAKLSKVDISTTVENWDARNKFLKVEFPVNIRNDFASYETQ 861
Query: 405 TGYLSRPTHRNTSWDSAKFEVCGHDWIHIGETNWGVTVLKEAIFGSSVVDGTVYLSLLRS 584
G RPTH NTSWD AKFEVC H + E + GV++L + +G S + LSLLRS
Sbjct: 862 FGITKRPTHYNTSWDVAKFEVCHHKFADYSEYSKGVSILNDCKYGFSTHGNLMRLSLLRS 921
Query: 585 PNSPDATADKKHIPHVFNYAIYPYDSSITNNKFGAISRLASQYNW 719
P +PDA AD H YAIYP+ +++++ +LA ++N+
Sbjct: 922 PKAPDAHADMG--THEIKYAIYPHRGALSSDTV----KLAHEFNY 960
>sp|P46081|BXCN_CLOBO Botulinum neurotoxin type C1, nontoxic component
Length = 1196
Score = 33.1 bits (74), Expect = 0.93
Identities = 46/202 (22%), Positives = 80/202 (39%), Gaps = 10/202 (4%)
Frame = +3
Query: 147 VDIECIPSFRILQEIEVVKSNRSVSLLYKSRLENTQTT---IEQSITIYDNVEYCNMCTK 317
V I+ I S I +V N S+ + S L+N T+ I + DN +
Sbjct: 988 VSIDQILSIYSTNIISLVNKNNSIYVEELSVLDNPITSEEVIRNYFSYLDNSYIRDSSKS 1047
Query: 318 VIEWNETHKMMKVKIP--TVVNATDAQYCTQTGYLSRPTHRNTSWDSAKFEVCGHDWIHI 491
++E+N+ +++ P ++ D YLS + S KF++ D +
Sbjct: 1048 LLEYNKNYQLYNYVFPETSLYEVND----NNKSYLSLKNTDGINISSVKFKLINIDESKV 1103
Query: 492 GETNWGVTVLKEAIFGSSVVDGTV-YLSLLRSPNSPDATADKKHIPHV-FNYAIYPYDSS 665
W ++ V+DGT YL + N + K + + N ++ D
Sbjct: 1104 YVQKWDECII-------CVLDGTEKYLDISPENNRIQLVSSKDNAKKITVNTDLFRPDC- 1155
Query: 666 IT---NNKFGAISRLASQYNWM 722
IT N+K+ ++S YNWM
Sbjct: 1156 ITFSYNDKYFSLSLRDGDYNWM 1177
>sp|Q64929|VP4_AHSV4 VP4 core protein (Inner capsid protein VP4)
Length = 642
Score = 32.3 bits (72), Expect = 1.6
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 5/72 (6%)
Frame = +1
Query: 550 WTELFIYLFYDHLTVPMPQLTRNTFLMFSIMRFILMIH---R*QIINLVRSLVLPVS--I 714
W E + +FY LT P+P L+ F+ +M L I+ Q+ ++++ L L VS +
Sbjct: 492 WAENYAVIFYHALTSPVPDLSLCRFIGLRLMSSTLRINSDRAHQVTDILKKLGLDVSGHL 551
Query: 715 IGCVPGNMNMSD 750
C+ N ++D
Sbjct: 552 FICLMSNSYVAD 563
>sp|Q62IJ6|ATKA_BURMA Potassium-transporting ATPase A chain (Potassium-translocating
ATPase A chain) (ATP phosphohydrolase
[potassium-transporting] A chain) (Potassium binding and
translocating subunit A)
Length = 602
Score = 31.2 bits (69), Expect = 3.5
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +3
Query: 624 PHVFNYAIYPYDSSITNN--KFGAISRLASQYNWMCA 728
PH F+ +Y + S+ NN FG +S YNWM A
Sbjct: 489 PHGFSEILYAFSSAANNNGSAFGGLSVNTPFYNWMTA 525
>sp|Q63VS3|ATKA_BURPS Potassium-transporting ATPase A chain (Potassium-translocating
ATPase A chain) (ATP phosphohydrolase
[potassium-transporting] A chain) (Potassium binding and
translocating subunit A)
Length = 602
Score = 31.2 bits (69), Expect = 3.5
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Frame = +3
Query: 624 PHVFNYAIYPYDSSITNN--KFGAISRLASQYNWMCA 728
PH F+ +Y + S+ NN FG +S YNWM A
Sbjct: 489 PHGFSEILYAFSSAANNNGSAFGGLSVNTPFYNWMTA 525
>sp|O67244|FLGB_AQUAE Flagellar basal-body rod protein flgB
Length = 124
Score = 30.8 bits (68), Expect = 4.6
Identities = 11/21 (52%), Positives = 14/21 (66%)
Frame = +1
Query: 208 IGLYRCYTNLAWKTHKLLLNN 270
+ LY+ Y N WK HK+LL N
Sbjct: 7 VNLYKKYINFTWKRHKVLLGN 27
>sp|P36135|UTH1_YEAST UTH1 protein
Length = 450
Score = 30.0 bits (66), Expect = 7.9
Identities = 20/61 (32%), Positives = 26/61 (42%)
Frame = +3
Query: 492 GETNWGVTVLKEAIFGSSVVDGTVYLSLLRSPNSPDATADKKHIPHVFNYAIYPYDSSIT 671
G NW VL G+ DG YLS++ +PN+ +A FN I D S
Sbjct: 371 GVGNWAPVVL-----GAGYTDGITYLSIIPNPNNKEAPN--------FNIKIVATDGSTV 417
Query: 672 N 674
N
Sbjct: 418 N 418
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,357,370
Number of Sequences: 369166
Number of extensions: 2162285
Number of successful extensions: 5075
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4879
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5072
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)