Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_O16
(777 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 87 5e-17
sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprote... 87 5e-17
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 80 8e-15
sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 79 2e-14
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 47 6e-05
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 45 3e-04
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 45 3e-04
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 45 3e-04
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 44 6e-04
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 43 0.001
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 87.0 bits (214), Expect = 5e-17
Identities = 64/200 (32%), Positives = 102/200 (51%), Gaps = 10/200 (5%)
Frame = +2
Query: 11 SKIKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVE 187
SK+ D +FN+FCLYGNVEK+K +++ +A V+M++ A + + LN +F +++
Sbjct: 358 SKMNCDRVFNVFCLYGNVEKVKF-MKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMN 416
Query: 188 ISISKFTEI---------TDSVPNKDPVESFNSDFYNRXXXXXXXXXXXXXXXQTLHFFN 340
+ +SK I S KD ES N+ F LHFFN
Sbjct: 417 VCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRF---STPEQAAKNRIQHPSNVLHFFN 473
Query: 341 VPSTFTAEEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVVMVN 520
P T E ++ VK P+ V +F K S+R S +GL+E+D+ S+A+E + +N
Sbjct: 474 APLEVTEENFFEICDELGVKRPTSVKVFSGK--SERSS--SGLLEWDSKSDALETLGFLN 529
Query: 521 HTRLLLPQVSHPFHIKLSFS 580
H ++ P +P+ +KL FS
Sbjct: 530 HYQMKNPNGPYPYTLKLCFS 549
>sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 558
Score = 87.0 bits (214), Expect = 5e-17
Identities = 64/200 (32%), Positives = 102/200 (51%), Gaps = 10/200 (5%)
Frame = +2
Query: 11 SKIKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVE 187
SK+ D +FN+FCLYGNVEK+K +++ +A V+M++ A + + LN +F +++
Sbjct: 361 SKMNGDRVFNVFCLYGNVEKVKF-MKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLN 419
Query: 188 ISISKFTEI---------TDSVPNKDPVESFNSDFYNRXXXXXXXXXXXXXXXQTLHFFN 340
+ +SK I S KD ES N+ F LHFFN
Sbjct: 420 VCVSKQPAIMPGQSYGLEDGSCSYKDFSESRNNRF---STPEQAAKNRIQHPSNVLHFFN 476
Query: 341 VPSTFTAEEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVVMVN 520
P T E ++ VK PS V +F K S+R S +GL+E+++ S+A+E + +N
Sbjct: 477 APLEVTEENFFEICDELGVKRPSSVKVFSGK--SERSS--SGLLEWESKSDALETLGFLN 532
Query: 521 HTRLLLPQVSHPFHIKLSFS 580
H ++ P +P+ +KL FS
Sbjct: 533 HYQMKNPNGPYPYTLKLCFS 552
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 79.7 bits (195), Expect = 8e-15
Identities = 53/196 (27%), Positives = 99/196 (50%), Gaps = 7/196 (3%)
Frame = +2
Query: 14 KIKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEI 190
K+ +FNLFCLYGN+EK+K ++T +A V+M + A E + LN + +F K++ +
Sbjct: 346 KMNCSRVFNLFCLYGNIEKVKF-MKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNV 404
Query: 191 SISKFTEITDS--VPNKDPVESFNSDFYNRXXXXXXXXXXXXXXXQ----TLHFFNVPST 352
+SK + S +D S+ ++ Q LH++NVP
Sbjct: 405 CVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLC 464
Query: 353 FTAEEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVVMVNHTRL 532
T E + +V + +F K +++ ++GL+E++ ++A+E + +NH ++
Sbjct: 465 VTEETFTKLCNDHEVLTFIKYKVFDAKPSAKT---LSGLLEWECKTDAVEALTALNHYQI 521
Query: 533 LLPQVSHPFHIKLSFS 580
+P S+P+ +KL FS
Sbjct: 522 RVPNGSNPYTLKLCFS 537
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
Length = 591
Score = 78.6 bits (192), Expect = 2e-14
Identities = 53/196 (27%), Positives = 98/196 (50%), Gaps = 7/196 (3%)
Frame = +2
Query: 14 KIKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEI 190
K+ +FNLFCLYGN+EK+K ++T +A V+M + A E + LN + +F K++ +
Sbjct: 395 KMNCSRVFNLFCLYGNIEKVKF-MKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNV 453
Query: 191 SISKFTEITDS--VPNKDPVESFNSDFYNRXXXXXXXXXXXXXXXQ----TLHFFNVPST 352
+SK + S +D S+ ++ Q LH++NVP
Sbjct: 454 CVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLC 513
Query: 353 FTAEEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVVMVNHTRL 532
T E + +V + +F K +++ ++GL+E+ ++A+E + +NH ++
Sbjct: 514 VTEETFTKLCNDHEVLPFIKYKVFDAKASAKT---LSGLLEWKCKTDAVEALTALNHYQI 570
Query: 533 LLPQVSHPFHIKLSFS 580
+P S+P+ +KL FS
Sbjct: 571 RVPNGSNPYTLKLCFS 586
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 47.0 bits (110), Expect = 6e-05
Identities = 45/198 (22%), Positives = 92/198 (46%), Gaps = 6/198 (3%)
Frame = +2
Query: 17 IKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEIS 193
I LF LF +YG+V ++K+ + +++A VQM++ A+ + L+G ++ K + +
Sbjct: 339 ITPHGLFILFGVYGDVHRVKI-MFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRAT 397
Query: 194 ISKFTEIT---DSVPNKDPVESF-NSDFYNRXXXXXXXXXXXXXXXQTLHFFNVPSTFTA 361
+SK + + ++ + F NS + TLH N+P + T
Sbjct: 398 LSKHQAVQLpreGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTV 457
Query: 362 EEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVV-MVNHTRLLL 538
+++ ++FI A + F +K+ LI+ ++ EAI+ ++ + NH
Sbjct: 458 DDLKNLFIEAGCS--VKAFKFFQKDRKM------ALIQLGSVEEAIQALIELHNH----- 504
Query: 539 PQVSHPFHIKLSFSPTRI 592
+ H+++SFS + I
Sbjct: 505 -DLGENHHLRVSFSKSTI 521
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 44.7 bits (104), Expect = 3e-04
Identities = 43/199 (21%), Positives = 93/199 (46%), Gaps = 6/199 (3%)
Frame = +2
Query: 14 KIKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEI 190
++ +LF LF +YG+V+++K+ + +++A VQM++ A+ + LNG + K + I
Sbjct: 348 RVTPQSLFILFGVYGDVQRVKI-LFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRI 406
Query: 191 SISKFTEIT---DSVPNKDPVESF-NSDFYNRXXXXXXXXXXXXXXXQTLHFFNVPSTFT 358
++SK + + ++ + + NS + TLH N+P + +
Sbjct: 407 TLSKHQNVQLpreGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVS 466
Query: 359 AEEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVV-MVNHTRLL 535
E++ +F S + V F ++ LI+ ++ EA++ ++ + NH
Sbjct: 467 EEDLKVLFSS----NGGVVKGFKFFQKDRK----MALIQMGSVEEAVQALIDLHNH---- 514
Query: 536 LPQVSHPFHIKLSFSPTRI 592
+ H+++SFS + I
Sbjct: 515 --DLGENHHLRVSFSKSTI 531
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 44.7 bits (104), Expect = 3e-04
Identities = 44/198 (22%), Positives = 91/198 (45%), Gaps = 6/198 (3%)
Frame = +2
Query: 17 IKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEIS 193
I LF LF +YG+V ++K+ + +++A VQM++ A+ + L+G ++ K + +
Sbjct: 341 ITPHGLFILFGVYGDVHRVKI-MFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRAT 399
Query: 194 ISKFTEIT---DSVPNKDPVESF-NSDFYNRXXXXXXXXXXXXXXXQTLHFFNVPSTFTA 361
+SK + + ++ + F NS + TLH N+P + T
Sbjct: 400 LSKHQAVQLpreGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTM 459
Query: 362 EEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVV-MVNHTRLLL 538
+++ ++F A + F +K+ LI+ ++ EAI+ ++ + NH
Sbjct: 460 DDLKNLFTEAGCS--VKAFKFFQKDRKM------ALIQLGSVEEAIQALIELHNH----- 506
Query: 539 PQVSHPFHIKLSFSPTRI 592
+ H+++SFS + I
Sbjct: 507 -DLGENHHLRVSFSKSTI 523
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 44.7 bits (104), Expect = 3e-04
Identities = 44/198 (22%), Positives = 91/198 (45%), Gaps = 6/198 (3%)
Frame = +2
Query: 17 IKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEIS 193
I LF LF +YG+V ++K+ + +++A VQM++ A+ + L+G ++ K + +
Sbjct: 341 ITPHGLFILFGVYGDVHRVKI-MFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRAT 399
Query: 194 ISKFTEIT---DSVPNKDPVESF-NSDFYNRXXXXXXXXXXXXXXXQTLHFFNVPSTFTA 361
+SK + + ++ + F NS + TLH N+P + T
Sbjct: 400 LSKHQAVQLpreGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTM 459
Query: 362 EEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVV-MVNHTRLLL 538
+++ ++F A + F +K+ LI+ ++ EAI+ ++ + NH
Sbjct: 460 DDLKNLFTEAGCS--VKAFKFFQKDRKM------ALIQLGSVEEAIQALIELHNH----- 506
Query: 539 PQVSHPFHIKLSFSPTRI 592
+ H+++SFS + I
Sbjct: 507 -DLGENHHLRVSFSKSTI 523
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 43.5 bits (101), Expect = 6e-04
Identities = 42/199 (21%), Positives = 93/199 (46%), Gaps = 6/199 (3%)
Frame = +2
Query: 14 KIKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEI 190
++ +LF LF +YG+V+++K+ + +++A V+M++ A+ + LNG + K V I
Sbjct: 372 RVTPQSLFILFGVYGDVQRVKI-LFNKKENALVEMADGSQAQLAMSHLNGHKLHGKSVRI 430
Query: 191 SISKFTEIT---DSVPNKDPVESFNSDFYNRXXXXXXXXXXXXXXXQ-TLHFFNVPSTFT 358
++SK + + ++ + + S +R TLH N+P + +
Sbjct: 431 TLSKHQSVQLpreGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVS 490
Query: 359 AEEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTGLIEFDTISEAIEGVV-MVNHTRLL 535
+++ +F S + V F ++ LI+ ++ EA++ ++ + NH
Sbjct: 491 EDDLKSLFSS----NGGVVKGFKFFQKDRK----MALIQMGSVEEAVQALIELHNH---- 538
Query: 536 LPQVSHPFHIKLSFSPTRI 592
+ H+++SFS + I
Sbjct: 539 --DLGENHHLRVSFSKSTI 555
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/210 (21%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Frame = +2
Query: 14 KIKSDNLFNLFCLYGNVEKIKMGVETGQKSAFVQMSNREAAEFCLI-LNGITIFNKQVEI 190
++ +LF LF +Y +V+++K+ + +++A VQM++ A+ + LNG + K V I
Sbjct: 374 RVTPQSLFILFGVYCDVQRVKI-LFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRI 432
Query: 191 SISKFTEIT---DSVPNKDPVESF-NSDFYNRXXXXXXXXXXXXXXXQTLHFFNVPSTFT 358
++SK + + ++ + + NS + TLH N+P + +
Sbjct: 433 TLSKHQNVQLpreGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSIS 492
Query: 359 AEEIADVFISAKVKDPSQVVIFPRKNNSQRGSLVTG-----------LIEFDTISEAIEG 505
E++ +F S G +V G LI+ ++ EAI+
Sbjct: 493 EEDLKILF-------------------SSNGGIVKGFKFFQKDRKMALIQMGSVEEAIQA 533
Query: 506 VV-MVNHTRLLLPQVSHPFHIKLSFSPTRI 592
++ + NH + H+++SFS + I
Sbjct: 534 LIDLHNH------DLGENHHLRVSFSKSTI 557
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,598,572
Number of Sequences: 369166
Number of extensions: 1450613
Number of successful extensions: 4057
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3958
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4048
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)