Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_N02
(812 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UM11|FZR_HUMAN Fizzy-related protein homolog (Fzr) (Cd... 301 1e-81
sp|Q9R1K5|FZR_MOUSE Fizzy-related protein homolog (Fzr) (Cd... 296 3e-80
sp|O13286|SRW1_SCHPO WD-repeat containing protein srw1 (Sup... 235 1e-61
sp|O94423|MFR1_SCHPO Meiotic fizzy-related protein 1 223 6e-58
sp|P53197|CDH1_YEAST APC/C activator protein CDH1 (CDC20 ho... 215 1e-55
sp|Q62623|CC20_RAT Cell division cycle protein 20 homolog (... 209 7e-54
sp|Q12834|CDC20_HUMAN Cell division cycle protein 20 homolo... 209 9e-54
sp|Q9JJ66|CDC20_MOUSE Cell division cycle protein 20 homolo... 207 4e-53
sp|P78972|SLP1_SCHPO WD-repeat containing protein slp1 184 2e-46
sp|P26309|CDC20_YEAST APC/C activator protein CDC20 (Cell d... 135 1e-31
>sp|Q9UM11|FZR_HUMAN Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog) (hCDH1)
(CDC20-like protein 1)
Length = 496
Score = 301 bits (771), Expect = 1e-81
Identities = 154/250 (61%), Positives = 177/250 (70%), Gaps = 1/250 (0%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEF-KPLKEHRQEVCGLKWSLDKQYLASGGNDNR 177
LAWNAE L+SGSRDR + RD RT + + L+ HRQEVCGLKWS D Q LASGGNDN+
Sbjct: 277 LAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNK 336
Query: 178 LVVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPH 357
L+VWN +S L+P Y H AAVKAIAWSPH
Sbjct: 337 LLVWNHSS------------------------------LSPVQQYTEHLAAVKAIAWSPH 366
Query: 358 QHGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIV 537
QHGLLASGGGTADRCI+FWN LT Q + +DTGSQVCN+AWS H+NELVSTHGYSQNQI+
Sbjct: 367 QHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQIL 426
Query: 538 VWKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFEKQKSTKATTSNR 717
VWKYP T +AKLTGHS RVLYLA+SPDG +VTGAGDETLRFWNVF K +STK +
Sbjct: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESV 486
Query: 718 SSLDLFSGMR 747
S L+LF+ +R
Sbjct: 487 SVLNLFTRIR 496
>sp|Q9R1K5|FZR_MOUSE Fizzy-related protein homolog (Fzr) (Cdh1/Hct1 homolog)
Length = 493
Score = 296 bits (759), Expect = 3e-80
Identities = 153/250 (61%), Positives = 177/250 (70%), Gaps = 1/250 (0%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEF-KPLKEHRQEVCGLKWSLDKQYLASGGNDNR 177
LAWNA+ L+SGSRDR + RD RT + + L+ HRQEVCGLKWS D Q LASGGNDN+
Sbjct: 277 LAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNK 336
Query: 178 LVVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPH 357
L+VWN +S L+P Y H AAVKAIAWSPH
Sbjct: 337 LLVWNHSS------------------------------LSPVQQYTEHLAAVKAIAWSPH 366
Query: 358 QHGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIV 537
QHGLLASGGGTADRCI+FWN LT Q + +DTGSQVCN+AWS H+NELVSTHGYSQNQI+
Sbjct: 367 QHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQIL 426
Query: 538 VWKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFEKQKSTKATTSNR 717
VWKYP T +AKLTGHS RVLYLA+SPDG +VTGAGDETLRFWNVF K +STK +
Sbjct: 427 VWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESV--- 483
Query: 718 SSLDLFSGMR 747
S L+LF+ +R
Sbjct: 484 SVLNLFTRIR 493
>sp|O13286|SRW1_SCHPO WD-repeat containing protein srw1 (Suppressor of rad/wee1)
Length = 556
Score = 235 bits (599), Expect = 1e-61
Identities = 110/236 (46%), Positives = 146/236 (61%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
L+WN +L+SG RD ++ RD R F+ L HRQEVCGL+W+ ++ LASGGNDN L
Sbjct: 339 LSWNDHVLSSGGRDNHILHRDVRAPEHYFRVLTAHRQEVCGLEWNSNENLLASGGNDNAL 398
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
+VW+ + P + NH AAVKAI WSPHQ
Sbjct: 399 MVWD------------------------------KFEEKPLYSFHNHIAAVKAITWSPHQ 428
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIVV 540
G+LASGGGTADR IK WN +H++DTGSQVCN+ WS +NE +STHG+ +N++ +
Sbjct: 429 RGILASGGGTADRTIKLWNTQRGSMLHNIDTGSQVCNLLWSKQTNEFISTHGFMENEVAL 488
Query: 541 WKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFEKQKSTKATT 708
W YP + + L GH+ RVLYLA+SP+G N+VTGA DETLRFW +F+ + A+T
Sbjct: 489 WNYPSVSRVGTLKGHTDRVLYLAMSPNGENIVTGAADETLRFWKLFDSKSKHSAST 544
>sp|O94423|MFR1_SCHPO Meiotic fizzy-related protein 1
Length = 421
Score = 223 bits (567), Expect = 6e-58
Identities = 110/235 (46%), Positives = 141/235 (60%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
LAWN L SG +D + D R + +K H QE+CGL+W LASGGNDN L
Sbjct: 214 LAWNDNTLTSGGKDEVILHHDLRAPGCCAEMMKVHEQEICGLQWDRSLGQLASGGNDNNL 273
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
VW+ S P +E H AAVKAI WSPHQ
Sbjct: 274 FVWDYRSS------------------------------RPLHKFEEHTAAVKAIGWSPHQ 303
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIVV 540
G+LASGGGT DRC+ N LT + + +DTGSQVCN+AWS SNE+V+THG+++NQ+ +
Sbjct: 304 RGILASGGGTIDRCLTIHNTLTGRLQNKLDTGSQVCNMAWSKTSNEIVTTHGFAKNQVSL 363
Query: 541 WKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFEKQKSTKAT 705
WKYP +A LT H+ RVLYL++SPDG ++VTGAGDETLRFW +F K+ ++T
Sbjct: 364 WKYPSLKNIANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKLFNKKPKEEST 418
>sp|P53197|CDH1_YEAST APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty
1)
Length = 566
Score = 215 bits (547), Expect = 1e-55
Identities = 109/249 (43%), Positives = 151/249 (60%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
L+WN +L SGSRD + RD R F+ ++ H QEVCGLKW++ LASGGNDN +
Sbjct: 350 LSWNNHVLTSGSRDHRILHRDVRMPDPFFETIESHTQEVCGLKWNVADNKLASGGNDNVV 409
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
V+ TS+S P + ++ H AAVKA+AWSPH+
Sbjct: 410 HVYEGTSKS------------------------------PILTFDEHKAAVKAMAWSPHK 439
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIVV 540
G+LA+GGGTADR +K WN+ T + +D+GSQ+CN+ WS ++NELV++HGYS+ + +
Sbjct: 440 RGVLATGGGTADRRLKIWNVNTSIKMSDIDSGSQICNMVWSKNTNELVTSHGYSKYNLTL 499
Query: 541 WKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFEKQKSTKATTSNRS 720
W P+A L GHS RVL+L LS DG+ VV+GAGDETLR+W +F+K K+ N
Sbjct: 500 WDCNSMDPIAILKGHSFRVLHLTLSNDGTTVVSGAGDETLRYWKLFDKPKA--KVQPNSL 557
Query: 721 SLDLFSGMR 747
D F+ +R
Sbjct: 558 IFDAFNQIR 566
>sp|Q62623|CC20_RAT Cell division cycle protein 20 homolog (p55CDC)
Length = 499
Score = 209 bits (532), Expect = 7e-54
Identities = 106/245 (43%), Positives = 146/245 (59%), Gaps = 5/245 (2%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
L+WN+ +L+SGSR ++H D R + L H QEVCGL+W+ D ++LASGGNDN +
Sbjct: 274 LSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIV 333
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
VW +G G +G P + H AVKA+AW P Q
Sbjct: 334 NVW---------------PSGPGESGWV-----------PLQTFTQHQGAVKAVAWCPWQ 367
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIVV 540
+LA+GGGT+DR I+ WN+ + + +VD SQVC+I WSPH EL+S HG++QNQ+V+
Sbjct: 368 SNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSPHYKELISGHGFAQNQLVI 427
Query: 541 WKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFE-----KQKSTKAT 705
WKYP +A+L GH+ RVL L +SPDG+ V + A DETLR W FE +++ KA+
Sbjct: 428 WKYPTMAKVAELKGHTARVLSLTMSPDGATVASAAADETLRLWRCFELDPALRREREKAS 487
Query: 706 TSNRS 720
TS S
Sbjct: 488 TSKSS 492
>sp|Q12834|CDC20_HUMAN Cell division cycle protein 20 homolog (p55CDC)
Length = 499
Score = 209 bits (531), Expect = 9e-54
Identities = 107/253 (42%), Positives = 151/253 (59%), Gaps = 4/253 (1%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
L+WN+ +L+SGSR ++H D R + L H QEVCGL+W+ D ++LASGGNDN +
Sbjct: 274 LSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLV 333
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
VW S G GG + P + H AVKA+AW P Q
Sbjct: 334 NVW--PSAPGEGGWV------------------------PLQTFTQHQGAVKAVAWCPWQ 367
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIVV 540
+LA+GGGT+DR I+ WN+ + + +VD SQVC+I WSPH EL+S HG++QNQ+V+
Sbjct: 368 SNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVI 427
Query: 541 WKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFE----KQKSTKATT 708
WKYP +A+L GH+ RVL L +SPDG+ V + A DETLR W FE +++ + +
Sbjct: 428 WKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKAS 487
Query: 709 SNRSSLDLFSGMR 747
+ +SSL + G+R
Sbjct: 488 AAKSSL-IHQGIR 499
>sp|Q9JJ66|CDC20_MOUSE Cell division cycle protein 20 homolog (p55CDC) (mmCdc20)
Length = 499
Score = 207 bits (526), Expect = 4e-53
Identities = 101/227 (44%), Positives = 138/227 (60%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
L+WN+ +L+SGSR ++H D R + L H QEVCGL+W+ D ++LASGGNDN +
Sbjct: 274 LSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIV 333
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
VW +G G +G + P + H AVKA+AW P Q
Sbjct: 334 NVW---------------PSGPGESGWA-----------PLQTFTQHQGAVKAVAWCPWQ 367
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIVV 540
+LA+GGGT+DR I+ WN+ + + +VD SQVC+I WSPH EL+S HG++QNQ+V+
Sbjct: 368 SNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSPHYKELISGHGFAQNQLVI 427
Query: 541 WKYPGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFE 681
WKYP +A+L GH+ RVL L +SPDG+ V + A DETLR W FE
Sbjct: 428 WKYPTMAKVAELKGHTARVLGLTMSPDGATVASAAADETLRLWRCFE 474
>sp|P78972|SLP1_SCHPO WD-repeat containing protein slp1
Length = 488
Score = 184 bits (467), Expect = 2e-46
Identities = 97/229 (42%), Positives = 127/229 (55%), Gaps = 2/229 (0%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
L+WN +L+SGSR +H D R ++ + L+ H EVCGL W D LASGGNDN +
Sbjct: 269 LSWNRHVLSSGSRSGAIHHHDVRIANHQIGTLQGHSSEVCGLAWRSDGLQLASGGNDNVV 328
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
+W+ +RS + P NH AAVKA+AW P Q
Sbjct: 329 QIWD--ARSSI----------------------------PKFTKTNHNAAVKAVAWCPWQ 358
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPHSNELVSTHGYSQNQIVV 540
LLA+GGGT D+ I FWN T V++VD GSQV ++ WSPHS E++STHG+ N + +
Sbjct: 359 SNLLATGGGTMDKQIHFWNAATGARVNTVDAGSQVTSLIWSPHSKEIMSTHGFPDNNLSI 418
Query: 541 WKY--PGCTPLAKLTGHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFE 681
W Y G T + H RVLY ALSPDG + T A DE L+FW V++
Sbjct: 419 WSYSSSGLTKQVDIPAHDTRVLYSALSPDGRILSTAASDENLKFWRVYD 467
>sp|P26309|CDC20_YEAST APC/C activator protein CDC20 (Cell division control protein 20)
Length = 610
Score = 135 bits (340), Expect = 1e-31
Identities = 79/237 (33%), Positives = 116/237 (48%), Gaps = 10/237 (4%)
Frame = +1
Query: 1 LAWNAELLASGSRDRNVHLRDTRTSSTEFKPLKEHRQEVCGLKWSLDKQYLASGGNDNRL 180
L+W L+A+GSR + + D R EH EVCGL + D LASGGNDN +
Sbjct: 350 LSWLDTLIATGSRSGEIQINDVRIKQHIVSTWAEHTGEVCGLSYKSDGLQLASGGNDNTV 409
Query: 181 VVWNLTSRSGMGGTLGDRATGAGTTGSSVNSNAGTYSLNPFIIYENHAAAVKAIAWSPHQ 360
++W+ T + P + H AAVKA++W P+
Sbjct: 410 MIWD------------------------------TRTSLPQFSKKTHTAAVKALSWCPYS 439
Query: 361 HGLLASGGGTADRCIKFWNILTRQAVHSVDTGSQVCNIAWSPH---------SNELVSTH 513
+LASGGG D+ I FWN +T V S++TGSQV ++ W + E+V+T
Sbjct: 440 PNILASGGGQTDKHIHFWNSITGARVGSINTGSQVSSLHWGQSHTSTNGGMMNKEIVATG 499
Query: 514 GYSQNQIVVWKYPGCTPLAKLT-GHSCRVLYLALSPDGSNVVTGAGDETLRFWNVFE 681
G +N I V+ Y +A++ H R+ LSPDG+ + T GDE L+F+ +F+
Sbjct: 500 GNPENAISVYNYETKFKVAEVVHAHEARICCSQLSPDGTTLATVGGDENLKFYKIFD 556
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,528,140
Number of Sequences: 369166
Number of extensions: 2170708
Number of successful extensions: 8181
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5760
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7496
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)