Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_M06
(804 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75886|STAM2_HUMAN Signal transducing adapter molecule 2... 80 5e-15
sp|Q92783|STAM1_HUMAN Signal transducing adapter molecule 1... 79 2e-14
sp|O88811|STAM2_MOUSE Signal transducing adapter molecule 2... 79 2e-14
sp|P70297|STAM1_MOUSE Signal transducing adapter molecule 1... 78 3e-14
sp|Q5XHY7|STAM2_RAT Signal transducing adapter molecule 2 (... 76 1e-13
sp|O93436|STAM2_CHICK Signal transducing adapter molecule 2... 68 3e-11
sp|O28996|PUR7_ARCFU Putative phosphoribosylaminoimidazole-... 33 0.70
sp|Q9C4Z3|ACDE2_METTE Acetyl-CoA decarbonylase/synthase com... 32 2.7
sp|P53719|YN87_YEAST Hypothetical 23.1 kDa protein in URK1-... 31 4.5
sp|Q8TRZ5|ADE1_METAC Acetyl-CoA decarbonylase/synthase comp... 30 5.9
>sp|O75886|STAM2_HUMAN Signal transducing adapter molecule 2 (STAM-2)
Length = 525
Score = 80.5 bits (197), Expect = 5e-15
Identities = 55/175 (31%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Frame = +1
Query: 4 PTPV-IDESKVDECILLIEDADPTGELRPDPPELSKLEAQCRVMGPLIDQELEKVDRHYN 180
P PV IDE K+D + +++ DPT + +PD +L LE C+ MGP+ID++LE++DR ++
Sbjct: 287 PEPVYIDEDKMDRALQVLQSIDPT-DSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHS 345
Query: 181 MLVELNRKTIESFQLYNELMTQGGMSRPTNYMWPANMPAAHAQYTS--LPLQDXXXXXXX 354
L ELN K +E+ +LYN+L+ + P ++ P AH S +P+Q
Sbjct: 346 ELSELNVKVLEALELYNKLVNEA----PVYSVYSKLHPPAHYPPASSGVPMQTY------ 395
Query: 355 XXXXXLNDPMMYQTMNYYGNMNRDSLFGQAFAMNKNQQLPNRNYPATSNINQKST 519
P+ NY G Q++++ +Q P R+ P N+N T
Sbjct: 396 --------PVQSHGGNYMGQSIHQVTVAQSYSLGPDQIGPLRSLP--PNVNSSVT 440
>sp|Q92783|STAM1_HUMAN Signal transducing adapter molecule 1 (STAM-1)
Length = 540
Score = 78.6 bits (192), Expect = 2e-14
Identities = 38/85 (44%), Positives = 56/85 (65%)
Frame = +1
Query: 1 PPTPVIDESKVDECILLIEDADPTGELRPDPPELSKLEAQCRVMGPLIDQELEKVDRHYN 180
P IDE K+D+ + +++ DP+ + +PD PEL LEA C MGPLID++LE +DR ++
Sbjct: 297 PEPAFIDEDKMDQLLQMLQSTDPSDD-QPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHS 355
Query: 181 MLVELNRKTIESFQLYNELMTQGGM 255
L ELN K +E+ LY +LM + M
Sbjct: 356 ELSELNVKVMEALSLYTKLMNEDPM 380
>sp|O88811|STAM2_MOUSE Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding
protein)
Length = 523
Score = 78.6 bits (192), Expect = 2e-14
Identities = 41/102 (40%), Positives = 65/102 (63%), Gaps = 1/102 (0%)
Frame = +1
Query: 4 PTPV-IDESKVDECILLIEDADPTGELRPDPPELSKLEAQCRVMGPLIDQELEKVDRHYN 180
P PV IDE K+D + +++ DP E +PD +L LE C+ MGP+ID++LE++DR ++
Sbjct: 287 PEPVYIDEGKMDRALQILQSIDPK-ESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHS 345
Query: 181 MLVELNRKTIESFQLYNELMTQGGMSRPTNYMWPANMPAAHA 306
L ELN K +E+ LYN+L+ + + + + PA+ P A A
Sbjct: 346 ELSELNVKVLEALDLYNKLVNEAPVYSVYSKLHPAHYPPAAA 387
>sp|P70297|STAM1_MOUSE Signal transducing adapter molecule 1 (STAM-1)
Length = 548
Score = 77.8 bits (190), Expect = 3e-14
Identities = 38/85 (44%), Positives = 55/85 (64%)
Frame = +1
Query: 1 PPTPVIDESKVDECILLIEDADPTGELRPDPPELSKLEAQCRVMGPLIDQELEKVDRHYN 180
P IDE K+D+ + +++ DP+ +PD PEL LEA C MGPLID++LE +DR ++
Sbjct: 297 PEPAFIDEDKMDQLLQMLQSTDPSDN-QPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHS 355
Query: 181 MLVELNRKTIESFQLYNELMTQGGM 255
L ELN K +E+ LY +LM + M
Sbjct: 356 ELSELNVKVMEALSLYTKLMNEDPM 380
>sp|Q5XHY7|STAM2_RAT Signal transducing adapter molecule 2 (STAM-2)
Length = 523
Score = 75.9 bits (185), Expect = 1e-13
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +1
Query: 4 PTPV-IDESKVDECILLIEDADPTGELRPDPPELSKLEAQCRVMGPLIDQELEKVDRHYN 180
P PV IDE K+D + +++ DP + +PD +L LE C+ MGP+ID++LE++DR ++
Sbjct: 287 PEPVYIDEGKMDRALQILQSIDPK-DPKPDSQDLLDLEDICQQMGPMIDEKLEEIDRRHS 345
Query: 181 MLVELNRKTIESFQLYNELMTQGGMSRPTNYMWPANMPAAHAQYTSLPLQDXXXXXXXXX 360
L ELN K +E+ +LYN+L+ + M + + PA A A +P+Q
Sbjct: 346 ELSELNVKVLEALELYNKLVNEAPMYSVYSKLHPAPYSATAA---GVPVQTY-------- 394
Query: 361 XXXLNDPMMYQTMNYYGNMNRDSLFGQAFAMNKNQQLPNRNYPATSN 501
P+ NY G+ Q++ + + +R+ P N
Sbjct: 395 ------PVQSHGGNYLGHGIHQVPVAQSYNLGPDPMGSSRSLPPNMN 435
>sp|O93436|STAM2_CHICK Signal transducing adapter molecule 2 (STAM-2) (Epidermal growth
factor receptor-associated protein with SH3 and TAM
domain)
Length = 468
Score = 68.2 bits (165), Expect = 3e-11
Identities = 42/113 (37%), Positives = 67/113 (59%), Gaps = 3/113 (2%)
Frame = +1
Query: 1 PPTPVIDESKVDECILLIEDADPTGELRPDPPELSKLEAQCRVMGPLIDQELEKVDRHYN 180
P IDE K+D+ + +++ DPT +L D +L E C+ MGP+ID++LE++DR ++
Sbjct: 286 PEAVYIDEDKMDKTLQVLQSIDPT-DLNLDT-DLLDSEVICQQMGPMIDEKLEEIDRKHS 343
Query: 181 MLVELNRKTIESFQLYNELMTQGGM-SRPTNYMWPANMP--AAHAQYTSLPLQ 330
L ELN K +E+ +LYN+LM + M S + PA P ++ S P+Q
Sbjct: 344 ELSELNVKVLEALELYNKLMNETPMYSAYSKLHHPAQYPPTSSGVSVQSYPVQ 396
>sp|O28996|PUR7_ARCFU Putative phosphoribosylaminoimidazole-succinocarboxamide synthase
(SAICAR synthetase)
Length = 331
Score = 33.5 bits (75), Expect = 0.70
Identities = 24/85 (28%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
Frame = +1
Query: 4 PTPVIDESKVDECILLIEDADPTGELRPDPPELSKLEAQCRVMGPLID--QELEKVDRH- 174
P +I + + E L+ + GE +P+ L+K+EA R+ P++D +LE VDR+
Sbjct: 117 PLEIIYRNSIPEGSSLLRRIE-RGEAKPEDFGLTKIEAGMRLERPIVDFSTKLEDVDRYL 175
Query: 175 -YNMLVELNRKTIESFQLYNELMTQ 246
++ E++ + E F+ EL+ +
Sbjct: 176 SHSEAKEISGLSDEEFEALKELVVK 200
>sp|Q9C4Z3|ACDE2_METTE Acetyl-CoA decarbonylase/synthase complex epsilon subunit 2 (ACDS
complex epsilon subunit 2)
Length = 170
Score = 31.6 bits (70), Expect = 2.7
Identities = 11/32 (34%), Positives = 20/32 (62%)
Frame = +1
Query: 571 NFQDLRSLPLQNNYSENSFQSLSNMSQQPHFS 666
NF D++S+ + NY +N+ S N+S+ H +
Sbjct: 130 NFSDVKSISIDRNYIQNATMSFGNLSKADHIA 161
>sp|P53719|YN87_YEAST Hypothetical 23.1 kDa protein in URK1-SMM1 intergenic region
Length = 212
Score = 30.8 bits (68), Expect = 4.5
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 4/78 (5%)
Frame = +1
Query: 481 NYPATSNINQKSTFPXXXXXXXXXAVLPAMNF-QDLRSLPLQNNYSE---NSFQSLSNMS 648
NY A S + T P +VLPA +F Q Q SE SF + S+
Sbjct: 91 NYTAASCLTSDPTSPSLLPSSRRNSVLPASDFHQCAHHKNFQRRASEPQLPSFDNRSSSE 150
Query: 649 QQPHFSYVQNDQTFPTQD 702
+ SY Q+ FP D
Sbjct: 151 MKRSVSYAQHSMMFPISD 168
>sp|Q8TRZ5|ADE1_METAC Acetyl-CoA decarbonylase/synthase complex epsilon subunit 1 (ACDS
complex epsilon subunit 1)
Length = 170
Score = 30.4 bits (67), Expect = 5.9
Identities = 10/34 (29%), Positives = 22/34 (64%)
Frame = +1
Query: 565 AMNFQDLRSLPLQNNYSENSFQSLSNMSQQPHFS 666
A NF +L+++ ++ Y +N+ S N+S+ H++
Sbjct: 128 AKNFSNLKTIAIERGYIQNATMSFGNLSKADHYA 161
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,130,719
Number of Sequences: 369166
Number of extensions: 1735936
Number of successful extensions: 4178
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4041
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4164
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)