Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_L19
(625 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CZU6|CISY_MOUSE Citrate synthase, mitochondrial precursor 334 9e-92
sp|P00889|CISY_PIG Citrate synthase, mitochondrial precursor 334 1e-91
sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial precursor 330 1e-90
sp|P23007|CISY_CHICK Citrate synthase, mitochondrial 317 1e-86
sp|P34575|CISY_CAEEL Probable citrate synthase, mitochondri... 316 3e-86
sp|P51044|CISY_ASPNG Citrate synthase, mitochondrial precursor 263 2e-70
sp|O00098|CISY_EMENI Citrate synthase, mitochondrial precursor 259 3e-69
sp|P00890|CISY1_YEAST Citrate synthase, mitochondrial precu... 259 4e-69
sp|P79024|CISY_CANTR Citrate synthase, mitochondrial precursor 258 1e-68
sp|P08679|CISY2_YEAST Citrate synthase, peroxisomal 254 1e-67
>sp|Q9CZU6|CISY_MOUSE Citrate synthase, mitochondrial precursor
Length = 464
Score = 334 bits (857), Expect = 9e-92
Identities = 154/208 (74%), Positives = 182/208 (87%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMRG+KGLV ETSVLDP+EGIRFRGYSIPECQK+LPK++GGE+PLPEGLF+LL+TG++
Sbjct: 69 YGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLFWLLVTGQM 128
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PTEEQV W+S+EWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY EG
Sbjct: 129 PTEEQVSWLSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEG 188
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
++++ YWE +YED MDLIAKL VAA IYRNLYR+G+S+G ID+ DWS NF M+GY D
Sbjct: 189 MNRAKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSRLDWSHNFTNMLGYTD 248
Query: 542 PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
P FTELMRLYLTIHSDHEGGNVSAHT H
Sbjct: 249 PQFTELMRLYLTIHSDHEGGNVSAHTSH 276
>sp|P00889|CISY_PIG Citrate synthase, mitochondrial precursor
Length = 464
Score = 334 bits (856), Expect = 1e-91
Identities = 155/208 (74%), Positives = 180/208 (86%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMRG+KGLV ETSVLDP+EGIRFRGYSIPECQK+LPK++GGE+PLPEGLF+LL+TG+I
Sbjct: 69 YGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKMLPKAKGGEEPLPEGLFWLLVTGQI 128
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PTEEQV W+SKEWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY EG
Sbjct: 129 PTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEG 188
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
+ ++ YWE +YED MDLIAKL VAA IYRNLYR+G+S+G ID+ DWS NF M+GY D
Sbjct: 189 IHRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLGYTD 248
Query: 542 PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
FTELMRLYLTIHSDHEGGNVSAHT H
Sbjct: 249 AQFTELMRLYLTIHSDHEGGNVSAHTSH 276
>sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial precursor
Length = 466
Score = 330 bits (847), Expect = 1e-90
Identities = 153/208 (73%), Positives = 180/208 (86%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMRG+KGLV ETSVLDP+EGIRFRG+SIPECQK+LPK++GGE+PLPEGLF+LL+TG I
Sbjct: 69 YGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLFWLLVTGHI 128
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PTEEQV W+SKEWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY +G
Sbjct: 129 PTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESNFARAYAQG 188
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
+S++ YWE +YEDSMDLIAKL VAA IYRNLYR+G+ +G ID++ DWS NF M+GY D
Sbjct: 189 ISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNFTNMLGYTD 248
Query: 542 PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
FTEL RLYLTIHSDHEGGNVSAHT H
Sbjct: 249 HQFTELTRLYLTIHSDHEGGNVSAHTSH 276
>sp|P23007|CISY_CHICK Citrate synthase, mitochondrial
Length = 433
Score = 317 bits (813), Expect = 1e-86
Identities = 150/208 (72%), Positives = 173/208 (83%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMRG+KGLV ETSVLDP+EGIRFRG+SIPECQK+LPK G +PLPEGLF+LL+TG+I
Sbjct: 42 YGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGXGGEPLPEGLFWLLVTGQI 101
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PT QV W+SKEWA RA LP HVV+M++NFP++LHPMSQL AA ALNSES F +AY EG
Sbjct: 102 PTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEG 161
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
+ ++ YWE VYE +MDLIAKL VAA IYRNLYR G+S+G ID+ DWS NF M+GY D
Sbjct: 162 ILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTD 221
Query: 542 PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
FTELMRLYLTIHSDHEGGNVSAHT H
Sbjct: 222 AQFTELMRLYLTIHSDHEGGNVSAHTSH 249
>sp|P34575|CISY_CAEEL Probable citrate synthase, mitochondrial precursor
Length = 468
Score = 316 bits (810), Expect = 3e-86
Identities = 148/208 (71%), Positives = 175/208 (84%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMR +KG+VTETSVLDPEEGIRFRGYSIPECQK+LPK++GGE+PLPE +++LL TG +
Sbjct: 71 YGGMRSMKGMVTETSVLDPEEGIRFRGYSIPECQKLLPKAKGGEEPLPEAIWWLLCTGDV 130
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
P+E Q I+KEW +RADLP HVV M++NFP +LHPM+Q +AA AALN+ESKF AY G
Sbjct: 131 PSEAQTAAITKEWNARADLPTHVVRMLDNFPDNLHPMAQFIAAIAALNNESKFAGAYARG 190
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
V+K+ YWE YEDSMDL+AKL TVAA+IYRNLYRDG++V ID KDWS NF M+GY+D
Sbjct: 191 VAKASYWEYAYEDSMDLLAKLPTVAAIIYRNLYRDGSAVSVIDPKKDWSANFSSMLGYDD 250
Query: 542 PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
P F ELMRLYL IHSDHEGGNVSAHT H
Sbjct: 251 PLFAELMRLYLVIHSDHEGGNVSAHTSH 278
>sp|P51044|CISY_ASPNG Citrate synthase, mitochondrial precursor
Length = 475
Score = 263 bits (673), Expect = 2e-70
Identities = 131/209 (62%), Positives = 160/209 (76%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGG RG+K LV E SVLD EEGIRFRG +IPECQ++LPK+ GG++PLPEGLF+LLLTG+I
Sbjct: 78 YGGARGVKCLVWEGSVLDSEEGIRFRGRTIPECQELLPKAPGGQEPLPEGLFWLLLTGEI 137
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PTE+QV+ +S EWA+R+DLP + +I+ PS+LHPMSQ A AL ES F KAY +G
Sbjct: 138 PTEQQVRDLSAEWAARSDLPKFIEELIDRCPSTLHPMSQFSLAVTALEHESAFAKAYAKG 197
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
++K YW +EDSMDLIAKL T+AA IYRN+++DG V I KD+S N +GY D
Sbjct: 198 INKKDYWNYTFEDSMDLIAKLPTIAAKIYRNVFKDG-KVAPIQKDKDYSYNLANQLGYGD 256
Query: 542 PS-FTELMRLYLTIHSDHEGGNVSAHTCH 625
+ F ELMRLYLTIHSDHEGGNVSAHT H
Sbjct: 257 NNDFVELMRLYLTIHSDHEGGNVSAHTTH 285
>sp|O00098|CISY_EMENI Citrate synthase, mitochondrial precursor
Length = 474
Score = 259 bits (663), Expect = 3e-69
Identities = 128/209 (61%), Positives = 158/209 (75%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGG RG+K LV E SVLD EEGIRFRG +IPECQK+LPK+ GGE+PLPEGLF+LLLTG++
Sbjct: 78 YGGARGVKCLVWEGSVLDSEEGIRFRGLTIPECQKLLPKAPGGEEPLPEGLFWLLLTGEV 137
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
P+E+QV+ +S EWA+R+DLP + +I+ PS+LHPM+Q A AL ES F KA +G
Sbjct: 138 PSEQQVRDLSAEWAARSDLPKFIEELIDRVPSTLHPMAQFSLAVTALEHESAFAKATAKG 197
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
++K YW +EDSMDLIAKL T+AA IYRN+++DG V I KD+S N +G+ D
Sbjct: 198 INKKEYWHYTFEDSMDLIAKLPTIAAKIYRNVFKDG-KVAPIQKDKDYSYNLANQLGFAD 256
Query: 542 -PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
F ELMRLYLTIHSDHEGGNVSAHT H
Sbjct: 257 NKDFVELMRLYLTIHSDHEGGNVSAHTTH 285
>sp|P00890|CISY1_YEAST Citrate synthase, mitochondrial precursor
Length = 479
Score = 259 bits (662), Expect = 4e-69
Identities = 122/208 (58%), Positives = 160/208 (76%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMRGIKGLV E SVLDPEEGIRFRG +IPE Q+ LPK++G +PLPE LF+LLLTG+I
Sbjct: 81 YGGMRGIKGLVWEGSVLDPEEGIRFRGRTIPEIQRELPKAEGSTEPLPEALFWLLLTGEI 140
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PT+ QVK +S + A+R+++P HV+ ++++ P LHPM+Q A AL SESKF KAY +G
Sbjct: 141 PTDAQVKALSADLAARSEIPEHVIQLLDSLPKDLHPMAQFSIAVTALESESKFAKAYAQG 200
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
VSK YW +EDS+DL+ KL +A+ IYRN+++DG + D + D+ +N +++GYE+
Sbjct: 201 VSKKEYWSYTFEDSLDLLGKLPVIASKIYRNVFKDG-KITSTDPNADYGKNLAQLLGYEN 259
Query: 542 PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
F +LMRLYLTIHSDHEGGNVSAHT H
Sbjct: 260 KDFIDLMRLYLTIHSDHEGGNVSAHTTH 287
>sp|P79024|CISY_CANTR Citrate synthase, mitochondrial precursor
Length = 467
Score = 258 bits (658), Expect = 1e-68
Identities = 128/209 (61%), Positives = 159/209 (76%), Gaps = 1/209 (0%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMRGIKGLV E SVLDP EGIRFRG +IP+ QK LPK+ GGE+PLPE LF+LLLTG++
Sbjct: 68 YGGMRGIKGLVWEGSVLDPIEGIRFRGRTIPDIQKELPKAPGGEEPLPEALFWLLLTGEV 127
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PTE Q + +S+E+A+R+ LP HV +I+ PS LHPM+Q A AL SES+F KAY +G
Sbjct: 128 PTEAQTRALSEEFAARSALPKHVEELIDRSPSHLHPMAQFSIAVTALESESQFAKAYAKG 187
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGY-E 538
V KS YW+ YEDS++L+AKL T+AA IYRN++ DG ID+ D+ N ++G+ E
Sbjct: 188 VHKSEYWKYTYEDSIELLAKLPTIAAKIYRNVFHDGKLPAQIDSKLDYGANLASLLGFGE 247
Query: 539 DPSFTELMRLYLTIHSDHEGGNVSAHTCH 625
+ F ELMRLYLTIHSDHEGGNVSAHT H
Sbjct: 248 NKEFLELMRLYLTIHSDHEGGNVSAHTTH 276
>sp|P08679|CISY2_YEAST Citrate synthase, peroxisomal
Length = 460
Score = 254 bits (650), Expect = 1e-67
Identities = 122/208 (58%), Positives = 158/208 (75%)
Frame = +2
Query: 2 YGGMRGIKGLVTETSVLDPEEGIRFRGYSIPECQKVLPKSQGGEQPLPEGLFFLLLTGKI 181
YGGMRGI G V E SVLDPE+GIRFRG +I + QK LPK++G QPLPE LF+LLLTG++
Sbjct: 62 YGGMRGIPGSVWEGSVLDPEDGIRFRGRTIADIQKDLPKAKGSSQPLPEALFWLLLTGEV 121
Query: 182 PTEEQVKWISKEWASRADLPGHVVSMINNFPSSLHPMSQLVAASAALNSESKFVKAYHEG 361
PT+ QV+ +S + SR++LP HVV +++N P LHPM+Q A AL SESKF KAY +G
Sbjct: 122 PTQAQVENLSADLMSRSELPSHVVQLLDNLPKDLHPMAQFSIAVTALESESKFAKAYAQG 181
Query: 362 VSKSVYWETVYEDSMDLIAKLSTVAAMIYRNLYRDGTSVGCIDNSKDWSENFVRMIGYED 541
+SK YW +EDS+DL+ KL +AA IYRN+++DG +G +D + D+++N V +IG +D
Sbjct: 182 ISKQDYWSYTFEDSLDLLGKLPVIAAKIYRNVFKDG-KMGEVDPNADYAKNLVNLIGSKD 240
Query: 542 PSFTELMRLYLTIHSDHEGGNVSAHTCH 625
F +LMRLYLTIHSDHEGGNVSAHT H
Sbjct: 241 EDFVDLMRLYLTIHSDHEGGNVSAHTSH 268
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,844,652
Number of Sequences: 369166
Number of extensions: 1591885
Number of successful extensions: 3869
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3697
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3816
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4926080070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)